KCNK12

KCNK12
Identifiers
Aliases	KCNK12 , K2p12.1, THIK-2, THIK2, potassium two pore domain channel subfamily K member 12
External IDs	OMIM: 607366 MGI: 2684043 HomoloGene: 11107 GeneCards: KCNK12
Gene location (Human)
Chr.	Chromosome 2 (human)
End	47,570,985 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	88,105,422 bp
RNA expression pattern
	Top expressed in
	olfactory bulb; ; trigeminal ganglion; ; spinal ganglia; ; inferior olivary nucleus; ; cerebellum; ; cerebellar cortex; ; cerebellar hemisphere; ; sural nerve; ; entorhinal cortex; ; middle temporal gyrus;
	Top expressed in
	cerebellar cortex; ; superior frontal gyrus; ; anterior horn of spinal cord; ; olfactory bulb; ; hippocampus proper; ; yolk sac; ; neural tube; ; bone marrow; ; mesencephalon; ; islet of Langerhans;
	More reference expression data
	n/a
Gene ontology
Molecular function	potassium channel activity ; voltage-gated ion channel activity ; potassium ion leak channel activity ;
Cellular component	integral component of membrane ; membrane ; integral component of plasma membrane ;
Biological process	potassium ion transport ; regulation of ion transmembrane transport ; ion transport ; stabilization of membrane potential ; potassium ion transmembrane transport ;
	Sources:Amigo / QuickGO
Orthologs
	56660
	210741
	ENSG00000184261
	ENSMUSG00000050138
	Q9HB15
	Q76M80
	NM_022055
	NM_199251
	NP_071338
	NP_954859
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 18, 2024

Potassium channel, subfamily K, member 12, also known as KCNK12 is a human gene. The protein encoded by this gene, K_2P12.1, is a potassium channel containing two pore-forming P domains.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000184261 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050138 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C (March 2001). "THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels". J. Biol. Chem. 276 (10): 7302–11. doi: 10.1074/jbc.M008985200 . PMID 11060316.

External links

KCNK12+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000184261 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000050138 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11060316-5] Rajan S, Wischmeyer E, Karschin C, Preisig-Müller R, Grzeschik KH, Daut J, Karschin A, Derst C (March 2001). "THIK-1 and THIK-2, a novel subfamily of tandem pore domain K+ channels". J. Biol. Chem. 276 (10): 7302–11. doi: 10.1074/jbc.M008985200 . PMID 11060316.

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KCNK12

Contents

See also

Related Research Articles

References

Further reading

External links