DUSP22

DUSP22
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WRM, 4WOH
Identifiers
Aliases	DUSP22 , JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX, dual specificity phosphatase 22
External IDs	OMIM: 616778; MGI: 1915926; HomoloGene: 86039; GeneCards: DUSP22; OMA:DUSP22 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	351,355 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	30,895,214 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; gingival epithelium; ; hair follicle; ; visceral pleura; ; monocyte; ; gonad; ; parietal pleura; ; Brodmann area 23; ; tibia; ; endothelial cell;
	Top expressed in
	lip; ; esophagus; ; spermatid; ; skin of external ear; ; digastric muscle; ; cumulus cell; ; cornea; ; skeletal muscle tissue; ; thoracic diaphragm; ; extraocular muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein tyrosine phosphatase activity ; phosphatase activity ; phosphoprotein phosphatase activity ; hydrolase activity ; protein tyrosine/serine/threonine phosphatase activity ; non-membrane spanning protein tyrosine phosphatase activity ; protein tyrosine kinase binding ;
Cellular component	cytoplasm ; nucleus ; cytosol ; plasma membrane ; filamentous actin ; leading edge of lamellipodium ;
Biological process	multicellular organism development ; negative regulation of T cell mediated immunity ; protein dephosphorylation ; peptidyl-tyrosine dephosphorylation ; cell population proliferation ; negative regulation of T cell activation ; negative regulation of transcription by RNA polymerase II ; transforming growth factor beta receptor signaling pathway ; regulation of cell population proliferation ; positive regulation of JNK cascade ; negative regulation of T cell receptor signaling pathway ; dephosphorylation ; apoptotic process ; negative regulation of cell migration ; negative regulation of focal adhesion assembly ; cellular response to epidermal growth factor stimulus ; negative regulation of non-membrane spanning protein tyrosine kinase activity ;
	Sources:Amigo / QuickGO
Orthologs
	56940
	105352
	ENSG00000112679
	ENSMUSG00000069255
	Q9NRW4
	Q99N11
	NM_001286555 ; NM_020185
	NM_001037955 ; NM_134068
	NP_001273484 ; NP_064570
	NP_001033044 ; NP_598829
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated July 09, 2024

Dual specificity protein phosphatase 22 is an enzyme that in humans is encoded by the DUSP22 gene.^[5]^[6]^[7]

Related Research Articles

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Dual specificity protein phosphatase CDC14A is an enzyme that in humans is encoded by the CDC14A gene.

Tyrosine-protein phosphatase non-receptor type 18 is an enzyme that in humans is encoded by the PTPN18 gene.

Dual specificity protein phosphatase 10 is an enzyme that in humans is encoded by the DUSP10 gene.

Dual specificity protein phosphatase 2 is an enzyme that in humans is encoded by the DUSP2 gene.

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 is an enzyme that in humans is encoded by the MAGI3 gene.

Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene.

Inositol-tetrakisphosphate 1-kinase is an enzyme that in humans is encoded by the ITPK1 gene.

Rh family, B glycoprotein, also known as RHBG, is an ammonia transporter protein which in humans is encoded by the RHBG gene.

Dual specificity protein phosphatase 16 is an enzyme that in humans is encoded by the DUSP16 gene.

Receptor-type tyrosine-protein phosphatase H is an enzyme that in humans is encoded by the PTPRH gene.

Tensin-1 is a protein that in humans is encoded by the TNS1 gene.

Dual specificity protein phosphatase 12 is an enzyme that in humans is encoded by the DUSP12 gene.

Dual specificity protein phosphatase 15 is an enzyme that in humans is encoded by the DUSP15 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000112679 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000069255 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Smith A, Price C, Cullen M, Muda M, King A, Ozanne B, Arkinstall S, Ashworth A (Sep 1997). "Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7)". Genomics. 42 (3): 524–7. doi:10.1006/geno.1997.4756. PMID 9205128.
↑ Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK (Nov 2001). "Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1". Proc Natl Acad Sci U S A. 98 (24): 13613–8. Bibcode:2001PNAS...9813613S. doi: 10.1073/pnas.231499098 . PMC 61089 . PMID 11717427.
↑ "Entrez Gene: DUSP22 dual specificity phosphatase 22".

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Dual specificity protein phosphatase 22

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000112679 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000069255 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9205128-5] Smith A, Price C, Cullen M, Muda M, King A, Ozanne B, Arkinstall S, Ashworth A (Sep 1997). "Chromosomal localization of three human dual specificity phosphatase genes (DUSP4, DUSP6, and DUSP7)". Genomics. 42 (3): 524–7. doi:10.1006/geno.1997.4756. PMID 9205128.

[pmid11717427-6] Shen Y, Luche R, Wei B, Gordon ML, Diltz CD, Tonks NK (Nov 2001). "Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1". Proc Natl Acad Sci U S A. 98 (24): 13613–8. Bibcode:2001PNAS...9813613S. doi: 10.1073/pnas.231499098 . PMC 61089 . PMID 11717427.

[entrez-7] "Entrez Gene: DUSP22 dual specificity phosphatase 22".

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DUSP22

Contents

Related Research Articles

References

Further reading

External links