CAMK2D

Last updated
CAMK2D
Protein CAMK2D PDB 2VN9.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases CAMK2D , CAMKD, calcium/calmodulin dependent protein kinase II delta
External IDs OMIM: 607708; MGI: 1341265; HomoloGene: 55561; GeneCards: CAMK2D; OMA:CAMK2D - orthologs
Orthologs
SpeciesHumanMouse
Entrez

817

108058

Ensembl

ENSG00000145349

ENSMUSG00000053819

UniProt

Q13557

Q6PHZ2

RefSeq (mRNA)
RefSeq (protein)
Location (UCSC) Chr 4: 113.42 – 113.76 Mb Chr 3: 126.39 – 126.64 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Calcium/calmodulin-dependent protein kinase type II delta chain is an enzyme that in humans is encoded by the CAMK2D gene. [5]

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca2+/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a delta chain. Four alternatively spliced transcript variants that encode three different isoforms have been characterized to date. Distinct isoforms of this chain have different expression patterns. [5]

Related Research Articles

<span class="mw-page-title-main">Calcium/calmodulin-dependent protein kinase type II subunit alpha</span> Protein found in humans

Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMKIIα), a.k.a.Ca2+/calmodulin-dependent protein kinase II alpha, is one subunit of CamKII, a protein kinase (i.e., an enzyme which phosphorylates proteins) that in humans is encoded by the CAMK2A gene.

<span class="mw-page-title-main">CAMK2B</span> Protein-coding gene in humans

Calcium/calmodulin-dependent protein kinase type II beta chain is an enzyme that in humans is encoded by the CAMK2B gene.

<span class="mw-page-title-main">ATF1</span> Protein-coding gene in humans

Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene.

<span class="mw-page-title-main">CAMK4</span> Protein-coding gene in humans

Calcium/calmodulin-dependent protein kinase type IV is an enzyme that in humans is encoded by the CAMK4 gene.

<span class="mw-page-title-main">CAMK2G</span> Protein-coding gene in humans

Calcium/calmodulin-dependent protein kinase type II gamma chain is an enzyme that in humans is encoded by the CAMK2G gene.

<span class="mw-page-title-main">CDK5R1</span> Protein-coding gene in the species Homo sapiens

Cyclin-dependent kinase 5 activator 1 is an enzyme that in humans is encoded by the CDK5R1 gene.

<span class="mw-page-title-main">Alpha-actinin-4</span> Protein-coding gene in the species Homo sapiens

Alpha-actinin-4 is a protein that in humans is encoded by the ACTN4 gene.

<span class="mw-page-title-main">RPS6KA2</span> Enzyme found in humans

Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene.

<span class="mw-page-title-main">AKAP5</span> Protein-coding gene in the species Homo sapiens

A-kinase anchor protein 5 is a protein that in humans is encoded by the AKAP5 gene.

<span class="mw-page-title-main">CAMK1</span> Protein-coding gene in humans

Calcium/calmodulin-dependent protein kinase type 1 is an enzyme that in humans is encoded by the CAMK1 gene.

<span class="mw-page-title-main">ATP2B2</span> Protein-coding gene in the species Homo sapiens

Plasma membrane calcium-transporting ATPase 2 is an enzyme that in humans is encoded by the ATP2B2 gene.

<span class="mw-page-title-main">ADD2</span> Protein-coding gene in the species Homo sapiens

Beta-adducin is a protein that in humans is encoded by the ADD2 gene.

<span class="mw-page-title-main">RRAD (gene)</span> Protein-coding gene in the species Homo sapiens

Ras Related Glycolysis Inhibitor and Calcium Channel Regulator (RRAD) is a protein that in humans is encoded by the RRAD gene. RRAD is a Ras-related small GTPase that is regulated by p53 and plays a role in the regulation of aerobic glycolysis.

<span class="mw-page-title-main">PDE1A</span> Protein-coding gene in the species Homo sapiens

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A is an enzyme that in humans is encoded by the PDE1A gene.

<span class="mw-page-title-main">CAMKK1</span> Protein-coding gene in humans

Calcium/calmodulin-dependent protein kinase kinase 1 is an enzyme that in humans is encoded by the CAMKK1 gene.

<span class="mw-page-title-main">CAMKK2</span> Protein-coding gene in humans

Calcium/calmodulin-dependent protein kinase kinase 2 is an enzyme that in humans is encoded by the CAMKK2 gene.

<span class="mw-page-title-main">GEM (gene)</span> Protein-coding gene in humans

GTP-binding protein GEM is a protein that in humans is encoded by the GEM gene.

<span class="mw-page-title-main">PPM1F</span> Protein-coding gene in the species Homo sapiens

Protein phosphatase 1F is an enzyme that in humans is encoded by the PPM1F gene.

<span class="mw-page-title-main">MYLK</span> Gene of the immunoglobulin superfamily

Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is encoded by the MYLK gene.

<span class="mw-page-title-main">MAPK12</span> Protein-coding gene in the species Homo sapiens

Mitogen-activated protein kinase 12, also known as extracellular signal-regulated kinase 6 (ERK6) or stress-activated protein kinase 3 (SAPK3), is an enzyme that in humans is encoded by the MAPK12 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000145349 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053819 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. 1 2 "Entrez Gene: CAMK2D calcium/calmodulin-dependent protein kinase (CaM kinase) II delta".

Further reading


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