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  1. Breast cancer (BC) is the most common cancer in women worldwide. Early diagnosis of BC could considerably improve outcomes. Since health literacy could influence preventive behaviors and women’s ability to mak...

    Authors: Sedighe Rezaie-Chamani, Minoor Lamyian, Fazlollah Ahmadi and Ali Montazeri
    Citation: BMC Cancer 2024 24:1201
    Content type: Research Published on:

  2. Acute promyelocytic leukemia (APL) is the sub-type of Acute myeloid leukemia (AML) which is described by differentiation block at promyelocytic stage and t(15; 17) translocation with All trans retinoic acid (A...

    Authors: Bazla Binte Nadeem, Aysha Bibi, Mudassir Khan, Gul Rukh Sajjad, Fazal Adnan, Zaheer Ahmad and Dilawar Khan
    Citation: BMC Cancer 2024 24:1200
    Content type: Research Published on:

  3. Colorectal cancer, a prevalent malignancy worldwide, poses a significant challenge due to the lack of effective prognostic tools. In this study, we aimed to develop a functional gene signature to stratify colo...

    Authors: Ziyan Zhu, Jikun Li, Zhenzhong Fa, Xuezhong Xu, Yue Wang, Jie Zhou and Yixin Xu
    Citation: BMC Cancer 2024 24:1199
    Content type: Research Published on:

  4. A dosimetric evaluation is still lacking in terms of clinical target volume (CTV) omission in stage III patients treated with 4D-CT Intensity-Modulated Radiation Therapy (IMRT).

    Authors: Wenxin Ding, Tian Xu, Hui Xiang, Jing Liang, Weiwei Liang, Nan Xiang, Jingsheng Zhao, Guoyin Li and Zewen Song
    Citation: BMC Cancer 2024 24:1198
    Content type: Research Published on:

  5. Physiologic MRI-based tumor habitat analysis has the potential to predict patient outcomes by identifying the spatiotemporal habitats of glioblastoma. This study aims to prospectively validate the cut-off for ...

    Authors: Hye Hyeon Moon, Ji Eun Park, NakYoung Kim, Young-Hoon Kim, Sang Woo Song, Chang Ki Hong, Jeong Hoon Kim and Ho Sung Kim
    Citation: BMC Cancer 2024 24:1197
    Content type: Study Protocol Published on:

  6. Lung cancer (LC) is the most common cancer among males and the third most common cancer among females worldwide. Focusing on primary prevention may be the main strategy for reducing the overall mortality of LC...

    Authors: Fatemeh Toorang, Monireh Sadat Seyyedsalehi, Bahareh Sasanfar, Hamideh Rashidian, Maryam Hadji, Mahin Gholipour, Maryam Marzban, Mahdieh Bakhshi, Abbas Rezaianzadeh, Paolo Boffetta and Kazem Zendehdel
    Citation: BMC Cancer 2024 24:1196
    Content type: Research Published on:

  7. Although malnutrition is common in cancer patients, its molecular mechanisms has not been fully clarified. This study aims to identify significantly differential metabolites, match the corresponding metabolic ...

    Authors: Liang Fu, Lixin Song, Xi Zhou, Lin Chen, Lushan Zheng, Dandan Hu, Sha Zhu, Yanting Hu, Daojun Gong, Chun-Liang Chen, Xianghong Ye and Shian Yu
    Citation: BMC Cancer 2024 24:1195
    Content type: Research Published on:

  8. Robot-assisted radical prostatectomy (RARP) gains increasing popularity in the surgical management of prostate cancer (PCa) but is challenged by its prohibitive expense. A domestic robotic system has been deve...

    Authors: Jie Dong, Ruoyu Ji, Liang Cui, Guanghua Liu, Yi Xie, Jingmin Zhou, Huizhen Wang, Weifeng Xu and Zhigang Ji
    Citation: BMC Cancer 2024 24:1194
    Content type: Research Published on:

  9. Combining immune checkpoint and proton pump inhibitors is widely used in cancer treatment. However, the drug-drug interactions of these substances are currently unknown. This study aimed to explore drug-drug i...

    Authors: Xiayang Ren, Lu Li, Yiran Chen, Xiangli Cui, Rui Wan and Yanfeng Wang
    Citation: BMC Cancer 2024 24:1193
    Content type: Research Published on:

  10. The association between gallstones/cholecystectomy and cancer remains inconclusive in the current literature. This study aimed to explore the causal connections between gallstones/cholecystectomy and cancer ri...

    Authors: Fei Teng, Youyin Tang, Zhangyu Lu, Kefei Chen and Zheyu Chen
    Citation: BMC Cancer 2024 24:1192
    Content type: Research Published on:

  11. Identifying primary hepatic angiosarcoma (PHA) preoperatively is challenging, often relying on postoperative pathology. Invasive biopsy increases bleeding risk, emphasizing the importance of early PHA diagnosi...

    Authors: Lei Jiang, Lijun Xie, Zhenheng Wu, Qiming Ke, Mo Chen, Wei Pan, Fuxiu Zhong, Haijie Hong, Jiangzhi Chen, Xinran Cai, Shun Chen, Ling Gan and Yanling Chen
    Citation: BMC Cancer 2024 24:1191
    Content type: Research Published on:

  12. Immune checkpoint inhibitors (ICIs) have become the recommended first-line treatment for advanced non-small cell lung cancer (NSCLC) without driver gene mutations. However, data on the failure patterns of firs...

    Authors: Jia-Yi Deng, Ming-Yi Yang, Xiao-Rong Yang, Zhi-Hong Chen, Chong-Rui Xu and Qing Zhou
    Citation: BMC Cancer 2024 24:1190
    Content type: Research Published on:

  13. Histone acetylation plays a critical role in the progression of acute myeloid leukemia (AML). This study aimed to explore the prognostic significance and biological implications of histone acetylation-related ...

    Authors: Xiaojuan Guo, Guinian Huang, Dafa Qiu, Huiqing He, Xiaomin Niu, Ziwen Guo and Yongbin Ye
    Citation: BMC Cancer 2024 24:1189
    Content type: Research Published on:

  14. Independent and valid prognostic predictors for locally advanced gastric cancer (LAGC) patients with non-elevated serum tumor markers (Triple-negative: CA199 < 37U/ml, CEA < 5 Âµg/ml and CA125 < 35U/ml) before ...

    Authors: Hua-Long Zheng, Ling-Kang Zhang, Chen-Bin Lv, Bin-Bin Xu, Jian-Xian Lin, Chao-Hui Zheng, Chang-Ming Huang and Jian-Wei Xie
    Citation: BMC Cancer 2024 24:1188
    Content type: Research Published on:

  15. N6-methyladenosine (m6A) is a prevalent mRNA modification known for its implications in various cancer types, yet its role in chromophobe renal cell carcinoma (chRCC) remains largely unexplored. In this study, we...

    Authors: Zhigang Chen, Junbo Yang, Wei Zhang, Yang Qian, Nan Zhang, Zixin Chen, Min Lu, Liyuan Ge, Cheng Liu, Xiaojun Tian, Guifang Jia, Lulin Ma and Baoguo Li
    Citation: BMC Cancer 2024 24:1187
    Content type: Research Published on:

  16. Breast cancer is the most common malignancy among women in the UK. Reconstruction – of which implant-based breast reconstruction (IBBR) is the most common – forms a core part of surgical management of breast c...

    Authors: Hannah I. Cook, Sevasti P. Glynou, Sara Sousi, David Zargaran, Stephen Hamilton and Afshin Mosahebi
    Citation: BMC Cancer 2024 24:1186
    Content type: Research Published on:

  17. The occurrence of complications following radical gastrectomy for gastric cancer significantly impacts patients’ quality of life. Elderly patients are susceptible to postoperative complications. This study see...

    Authors: Zhe-kui Liu, Wen-xing Ma, Jun-jie Zhang, Si-da Liu, Xiang-long Duan and Ze-zheng Wang
    Citation: BMC Cancer 2024 24:1185
    Content type: Research Published on:

  18. This study analyzed and discussed the characteristics of peripheral blood lymphocytes (PBLs) in patients with endometrial carcinoma (EC) to explore the PBLs’ clinical application value.

    Authors: Yingyu Tian, Yuchun Zhang, Xi Tang, Jing Liu, Qin Huang, Yi Chen, Qian Zhan and Hui Wang
    Citation: BMC Cancer 2024 24:1184
    Content type: Research Published on:

  19. Teaching effective methods for breast self-examination (BSE) to adolescent females is essential for promoting early detection and improving outcomes in breast cancer management. This study therefore aimed to c...

    Authors: Eunice Oluwakemi Ogunmodede, Dolapo Emmanuel Ajala, Joel Ojo Aluko, Rafiat Ajoke Anokwuru, Titilope Abisola Awotunde, Adetunmise Oluseyi Olajide, Taiwo Omotayo Dosumu, Oluwaseyi Isaiah Olabisi and Ronke Gbonjubola Ajala
    Citation: BMC Cancer 2024 24:1183
    Content type: Research Published on:

  20. Patients with small-cell lung cancer (SCLC) have few treatment options and dismal overall survival (OS) after failed platinum-based chemotherapy.

    Authors: Wei Wang, Guixian Wu, Wujun Luo, Ling Lin, Chao Zhou, Guifei Yao, Meifang Chen, Xiaomai Wu, Ziran Chen, Junhui Ye, Haihua Yang and Dongqing Lv
    Citation: BMC Cancer 2024 24:1182
    Content type: Research Published on:

  21. Comprehensive analysis of clinical evidence for breast cancer adipogenesis with prognosis is lacking. This study aims to consolidate the latest evidence on the relationship between adipogenesis and breast canc...

    Authors: Shihang Hu, Sze Keong Tey and Ava Kwong
    Citation: BMC Cancer 2024 24:1181
    Content type: Research Published on:

  22. To establish the pathological diagnosis of UTUC before treatment is profitable. At present, the conventional pathological diagnostic methods have certain problems. Besides, the urine-based DNA methylation test...

    Authors: Wei Wei, Panhong Fan, Zhishu Zhang, Danting Wu, Junfeng Liu, Lingdian Wang, Xiaoyu Duan, Xiaoli Zhang and Degang Ding
    Citation: BMC Cancer 2024 24:1180
    Content type: Research Published on:

  23. Several inflammatory indicators have been reported to have predictive value in many types of malignant cancer. This research was aimed to explore the ability of the monocyte-to-lymphocyte ratio (MLR) to predic...

    Authors: Bin-Feng Tao, Hai-Qiang Zhu, Lu-Nan Qi, Jian-Hong Zhong, Rong-yun Mai and Liang Ma
    Citation: BMC Cancer 2024 24:1179
    Content type: Research Published on:

  24. Lung cancer (LC), a paramount global life-threatening condition causing significant mortality, is most commonly characterized by its subtype, lung adenocarcinoma (LUAD). Concomitant with LC, pulmonary fibrosis...

    Authors: Haiyang Li, Xing Fu, Mingtao Liu, Jiaxi Chen, Wenhan Cao, Zhiman Liang, Zhangkai J. Cheng and Baoqing Sun
    Citation: BMC Cancer 2024 24:1178
    Content type: Research Published on:

  25. The brachytherapy (BT) and radical prostatectomy (RP) are two methods recommended in current guidelines for the treatment of localized prostate cancer (PCa). It is difficult to compare the oncological results ...

    Authors: Zaisheng Zhu, Yiyi Zhu, Hongqi Shi, Penfei Zhou, Yadong Xue, Ke Dong and Shengye Hu
    Citation: BMC Cancer 2024 24:1177
    Content type: Research Published on:

  26. To develop radiomics models based on multi-sequence MRI from two centers for the preoperative prediction of the WHO/ISUP grade of Clear Cell Renal Cell Carcinoma (ccRCC).

    Authors: Ruihong Chen, Qiaona Su, Yangyang Li, Pengxin Shen, Jianxin Zhang and Yan Tan
    Citation: BMC Cancer 2024 24:1176
    Content type: Research Published on:

  27. Long noncoding RNAs (lncRNAs) are crucial regulators of biological processes such as transcription interference and activation, chromatin remodeling, and mRNA translation. Uncontrolled gene expression could re...

    Authors: Neveen A. Hussein, Samia A. Ebied, Abdel Aziz M. Belal, Mohamad A. Ahmad and El Sayed A. Weheida
    Citation: BMC Cancer 2024 24:1175
    Content type: Research Published on:

  28. Salivary duct carcinoma (SDC) is a rare and aggressive subtype of salivary gland cancer, frequently associated with incurable recurrences and distant metastases (R/M). Proliferation of SDC relies on androgen r...

    Authors: Jetty A. M. Weijers, Gerald W. Verhaegh, G. Lassche, Adriana C. H. van Engen-van Grunsven, Chantal M. L. Driessen, Nielka P. van Erp, Marianne A. Jonker, Jack A. Schalken and Carla M. L. van Herpen
    Citation: BMC Cancer 2024 24:1174
    Content type: Study Protocol Published on:

  29. Exosomes are closely associated with different aspects of tumor-progression in patients with head and neck squamous cell carcinoma (HNSCC), such as angiogenesis or immune regulation. As extracellular vesicles ...

    Authors: Marie-Nicole Theodoraki, Diana Huber, Linda Hofmann, Lotte Werner, Christian Idel, Jonas Fleckner, Kirstin Plötze-Martin, Lutz Schütt, Cornelia Brunner, Reinhard Depping, Thomas K. Hoffmann, Karl-Ludwig Bruchhage and Ralph Pries
    Citation: BMC Cancer 2024 24:1173
    Content type: Research Published on:

  30. In the era of tyrosine kinase inhibitor (TKI) treatment, the progression of chronic myeloid leukemia (CML) remains a significant clinical challenge, and genetic biomarkers for the early identification of CML p...

    Authors: Jingwei Zhao, Guiran Wang, Guiling Yan, Mengting Zheng, Hongshuang Li, Yuanyuan Bai, Xiaoqun Zheng and Zhanguo Chen
    Citation: BMC Cancer 2024 24:1172
    Content type: Research Published on:

  31. The risk of cervical cancer progression in high-risk human papillomavirus (HR-HPV)-positive women is associated with cervical lesion severity and molecular heterogeneity. Classification systems based on p16 an...

    Authors: Haijun Luo, Yixiang Lian, Hong Tao, Yan Zhao, Zhigan Wang, Jing Zhou, Zirong Zhang and Shali Jiang
    Citation: BMC Cancer 2024 24:1171
    Content type: Research Published on:

  32. To retrospectively explore the clinical significance of radiotherapy to the distant metastatic lymph nodes (cervical/ clavicular/ mediastinal et al.) in metastatic cervical cancer. Hereinto, these cervicothora...

    Authors: Chi Fang, Suping Liu, Jie Xia, Xiaohua Wu, Jun Zhu and Guihao Ke
    Citation: BMC Cancer 2024 24:1170
    Content type: Research Published on:

  34. Tri-combination therapy based on hepatic arterial infusion chemotherapy (HAIC) of infusion fluorouracil, leucovorin, and oxaliplatin (FOLFOX-HAIC) plus immune checkpoint inhibitors (ICIs) and tyrosine kinase i...

    Authors: Liyang Sun, Zhiwen Hu, Wa Xie, Zhenyun Yang, Huilan Zeng, Yaojun Zhang, Minshan Chen, Dandan Hu, Zhongguo Zhou and Yangxun Pan
    Citation: BMC Cancer 2024 24:1168
    Content type: Research Published on:

  35. Metastatic pancreatic ductal adenocarcinoma (mPDAC) patients have very poor prognosis highlighting the urgent need of novel treatments. In this regard, repurposing non-oncology already-approved drugs might be ...

    Authors: Alfredo Budillon, Alessandra Leone, Eugenia Passaro, Lucrezia Silvestro, Francesca Foschini, Federica Iannelli, Maria Serena Roca, Marina Macchini, Francesca Bruzzese, Maria Laura Garcia Bermejo, Mercedes Rodriguez Garrote, Giampaolo Tortora, Michele Milella, Michele Reni, Claudia Fuchs, Eve Hewitt…
    Citation: BMC Cancer 2024 24:1167
    Content type: Study Protocol Published on:

  36. The prognosis of breast cancer patients with visceral metastasis (VM) is significantly worse than that of patients without VM. We aimed to evaluate EZH2 (enhancer of zeste homolog 2) mutation as a biomarker as...

    Authors: Fan Wu, Nani Li, Xiufeng Wu, Mulan Chen, Weiwei Huang, Xinhua Chen, Yi Hong, Lili Wang, Kan Chen, Lin Lin, Minjin You and Jian Liu
    Citation: BMC Cancer 2024 24:1166
    Content type: Research Published on:

  37. Cancer-associated fibroblasts (CAFs), as key cell populations in the tumor microenvironment (TME), play a crucial role in tumor regulation. Previous studies on a prognostic signature of 8 CAF-related genes in ...

    Authors: Lei Dong, Yumei Li, Xiaoyu Song, Caiyu Sun and Xicheng Song
    Citation: BMC Cancer 2024 24:1165
    Content type: Research Published on:

  38. The intricate interplay of cancer stem cell plasticity, along with the bidirectional transformation between epithelial-mesenchymal states, introduces further intricacy to offer insights into newer therapeutic ...

    Authors: Ankit Mathur, Chanchal Bareja, Milky Mittal, Anjali Singh and Daman Saluja
    Citation: BMC Cancer 2024 24:1164
    Content type: Research Published on:

  39. Breast cancer (BC) is the most common cancer in women, and its progression is closely related to the phenomenon of anoikis. Anoikis, the specific programmed death resulting from a lack of contact between cells...

    Authors: Mingzheng Tang, Yao Rong, Xiaofeng Li, Haibang Pan, Pengxian Tao, Zhihang Wu, Songhua Liu, Renmei Tang, Zhilong Liu and Hui Cai
    Citation: BMC Cancer 2024 24:1163
    Content type: Research Published on:

  40. Despite a high incidence of colorectal carcinoma, data regarding genetic aberrations in colorectal carcinoma (CRC) patients in Pakistan is scarce. This study aimed to determine the frequency of BRAFV600E mutation...

    Authors: Sobia Hassan, Talat Mirza, Ambrina Khatoon, Uzma Bukhari, Fouzia Shaikh and Asad Karim
    Citation: BMC Cancer 2024 24:1162
    Content type: Research Published on:

  41. Many studies have explored the clinicopathological features and prognosis between colorectal mucinous adenocarcinoma (MAC) and adenocarcinoma (AC) and have given different results. This meta-analysis summarize...

    Authors: Xiao Wang, Haoran Wang, Haoqing He, Kai Lv, Wenguang Yuan, Jingbo Chen and Hui Yang
    Citation: BMC Cancer 2024 24:1161
    Content type: Research Published on:

  42. To investigate the values of apparent diffusion coefficient (ADC) for the treatment response evaluation in pancreatic cancer (PC) patients receiving neoadjuvant therapy (NAT).

    Authors: Yufei Chen, Chao Ma, Panpan Yang, Kuanzheng Mao, Yisha Gao, Luguang Chen, Zhen Wang, Yun Bian, Chengwei Shao and Jianping Lu
    Citation: BMC Cancer 2024 24:1160
    Content type: Research Published on:

  43. eHealth may help closing gaps in the long-term follow-up care of former young age cancer patients. While its introduction to medical aftercare appears promising, it also faces obstacles in the course of its im...

    Authors: Tjorven Stamer, Pia Traulsen, Johannes Rieken, Teresa Schmahl, Ingo Menrath and Jost Steinhäuser
    Citation: BMC Cancer 2024 24:1159
    Content type: Research Published on:

  44. Post-translational modification pathway of protein ubiquitination is intricately associated with tumorigenesis. We previously reported elevated ubiquitin-conjugating enzyme 2T (UBE2T) as an independent risk fa...

    Authors: Yujie Deng, Xiaohui Chen, Xuzheng Chen, Chuanzhong Huang, Zhiguang Zhang, Zhenguo Xu, Xiurong Wang, Jiamin Wu, Li Li, Jun Song and Ruixiang Zhou
    Citation: BMC Cancer 2024 24:1158
    Content type: Research Published on:

  46. Absolute lymphocyte count (ALC) is a predictive and prognostic factor for various tumor types, including breast cancer. Palbociclib is a CDK4/6 inhibitor widely used for the treatment of metastatic estrogen re...

    Authors: Takayuki Kobayashi, Meiko Nishimura, Mari Hosonaga, Rika Kizawa, Saori Kawai, Yosuke Aoyama, Yukinori Ozaki, Ippei Fukada, Fumikata Hara, Toshimi Takano and Takayuki Ueno
    Citation: BMC Cancer 2024 24:1156
    Content type: Research Published on:

  47. The response of patients with colorectal cancer to chemotherapy is tightly correlated with their genomic variation. Among these, APC, TP53, KRAS, PIK3CA are the most frequently mutated genes in advanced colore...

    Authors: YiMeng Tang and Yao Fan
    Citation: BMC Cancer 2024 24:1155
    Content type: Research Published on:

  49. Effects of confounders on associations between diet and colorectal cancer (CRC) in observational studies can be minimized in Mendelian randomization (MR) approach. This study aimed to investigate observational...

    Authors: Tung Hoang, Sooyoung Cho, Ji-Yeob Choi, Daehee Kang and Aesun Shin
    Citation: BMC Cancer 2024 24:1153
    Content type: Research Published on:

  50. Tumor-infiltrating lymphocytes (TILs) are significantly implicated in regulating the tumor immune microenvironment (TIME) and immunotherapeutic response. However, little is known about the impact of the reside...

    Authors: Anning Zuo, Jinxiang Lv, Wenlong Jia, Yuhao Ba, Shutong Liu, Yuyuan Zhang, Siyuan Weng, Hui Xu, Long Liu, Libo Wang, Xinwei Han and Zaoqu Liu
    Citation: BMC Cancer 2024 24:1152
    Content type: Research Published on:

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