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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Individualized Plastic and Reconstructive Surgery

edited by

Paul Immanuel Heidekrueger

, Peter Niclas Broer and Denis C. Ehrl

submission deadline 20 Jan 2025 | 10 articles | Viewed by 15155 | Submission Open

Keywords: patient-specific reconstructive procedures; microsurgical precision techniques; autologous tissue transplantation; digital imaging and customization; biomaterials in reconstructive surgery; tissue engineering for plastic reconstruction; flap surgery innovations; personalized cleft surgery; personalized aesthetic surgery

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Epilepsy: Causes, Symptoms, Diagnosis, and Treatment

edited by

Emanuele Bartolini

submission deadline 20 Jan 2025 | 7 articles | Viewed by 14850 | Submission Open

Keywords: neurological diseases; brain; neurology; neuroscience; neuroimaging; fMRI; EEG; genetics

(This special issue belongs to the Section Clinical Neurology)

Clinical Advances and Future Perspectives in Vascular Surgery

edited by

George N. Kouvelos

Konstantinos Spanos

and

Petroula N. Nana

submission deadline 20 Jan 2025 | 8 articles | Viewed by 12507 | Submission Open

Keywords: vascular surgery; endovascular surgery; aortic surgery; peripheral arterial disease; carotid artery disease; EVAR; vascular access; aneurysm; complex aneurysm

(This special issue belongs to the Section General Surgery)

Total Joint Arthroplasty: Management and Future Opportunities

edited by

Riccardo Giorgino

and

Laura Mangiavini

submission deadline 20 Jan 2025 | 8 articles | Viewed by 11105 | Submission Open

Keywords: total joint arthroplasty; joint replacement; surgical techniques; robotic-assisted surgery; implant materials; post-operative care; patient outcomes; future opportunities; orthopedic surgery; innovation in arthroplasty

(This special issue belongs to the Section Orthopedics)

Non-small Cell Lung Cancer: Current Updates and Perspectives

edited by

Athina N. Markou

submission deadline 20 Jan 2025 | 3 articles | Viewed by 8277 | Submission Open

Keywords: non-small cell lung cancer (NSCLC); liquid biopsy; cell-free DNA (cfDNA); minimal residual disease (MRD); circulating tumor cells (CTCs); heterogeneity; epithelial– mesenchymal transition (EMT); tyrosine kinase inhibitor (TKI)

(This special issue belongs to the Section Pulmonology)

Clinical Advances in Pulmonary Heart Disease

edited by

Alexandra D. Arvanitaki

and Stephen John Wort

submission deadline 20 Jan 2025 | 3 articles | Viewed by 5666 | Submission Open

Keywords: pulmonary heart disease; pulmonary hypertension; diagnosis; treatment; clinical advances

(This special issue belongs to the Section Cardiovascular Medicine)

Guidelines for the Management of Severe Aortic Stenosis

edited by Srikanth Koneru

submission deadline 20 Jan 2025 | 2 articles | Viewed by 3521 | Submission Open

Keywords: aortic stenosis; low flow low gradient AS; TAVR; SAVR; multimodality imaging; valve in valve TAVR; patient prosthesis mismatch

(This special issue belongs to the Section Clinical Guidelines)

The Changing Landscape of Fertility Diagnosis and Treatment

edited by

Amanda N. Kallen

and

David B. Seifer

submission deadline 20 Jan 2025 | 3 articles | Viewed by 3329 | Submission Open

Keywords: infertility; reproductive aging; in vitro fertilization; fertility; ovarian aging; ovary; uterus; sperm; tubal factor infertility; male factor infertility; biomarkers

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Abdominal Hernia Repair: Current Strategies for the Management of Abdominal Wall Hernias

edited by

Sergio Huerta

submission deadline 20 Jan 2025 | 3 articles | Viewed by 3149 | Submission Open

Keywords: inguinal hernia; ventral hernia; femoral hernia; pantaloon hernia; parastomal hernia

(This special issue belongs to the Section General Surgery)

Novel Epidemiological Approaches in Clinical Pharmacology and Toxicology

edited by

Niccolò Lombardi

and

Giada Crescioli

submission deadline 20 Jan 2025 | 2 articles | Viewed by 2614 | Submission Open

Keywords: clinical pharmacology; toxicology; epidemiology; the value of real-world evidence; adverse drug reactions; drug safety

(This special issue belongs to the Section Pharmacology)

Review Special Issue Series: Recent Advances in Pharmacology

edited by

Alfredo Vannacci

and

Giada Crescioli

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1950 | Submission Open

Keywords: clinical pharmacology; pharmacovigilance; pharmacokinetics; pharmacodynamics; pharmacogenetics; pharmacoepidemiology; pharmacometrics; pregnancy and pediatrics; adults and elderly; safety; toxic and side effects; drug reactions

(This special issue belongs to the Section Pharmacology)

New Insights into Infectious Skin and Mucosal Diseases

edited by

Giulia Ciccarese

Sebastiano Recalcati

and Astrid Herzum

submission deadline 20 Jan 2025 | 2 articles | Viewed by 1501 | Submission Open

Keywords: exanthem; latent viruses; infectious diseases; skin eruptions; sexually transmitted infections

(This special issue belongs to the Section Dermatology)

New Advances in Cardiovascular Diseases: The Cutting Edge

edited by

Fabiana Lucà

submission deadline 20 Jan 2025 | 1 articles | Viewed by 1107 | Submission Open

Keywords: cardiovascular disease (CVD); preventive cardiology; cardiac pharmacology; coronary artery disease (CAD); heart failure (HF); atrial fibrillation (AF); supraventricular and ventricular arrhythmias

(This special issue belongs to the Section Cardiovascular Medicine)

Workplace Bullying and Health Outcomes

edited by

Giuseppe La Torre

and

Gabriele D’Ettorre

submission deadline 20 Jan 2025 | Viewed by 355 | Submission Open

Keywords: epidemiology; public health; occupational medicine; workplace bullying; mental health; patient outcomes; economic assessment

(This special issue belongs to the Section Epidemiology & Public Health)

Type 2 Diabetes: Advances and Challenges

edited by Ken-ichi Aihara

submission deadline 22 Jan 2025 | 1 articles | Viewed by 1078 | Submission Open

Keywords: type 2 diabetes; clinical research; innovative treatment; biomarker; diabetic complications; glucose monitoring

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Management of Liver Cancers

edited by Jayant Kumar and

Isabella Reccia

submission deadline 23 Jan 2025 | 2 articles | Viewed by 3807 | Submission Open

Keywords: hepatocellular carcinoma; cholangiocarcinoma; mixed hepatocellular carcinoma– cholangiocarcinoma; combined hepatocellular carcinoma-cholangiocarcinoma; liver cancers

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Management of Pelvic Organ Prolapse

edited by

Barbara Bodner-Adler

submission deadline 23 Jan 2025 | 1 articles | Viewed by 1515 | Submission Open

Keywords: pelvic organ prolapse; pessary treatment; uterus-preserving prolapse surgery; clinical management; clinical treatment

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights into Kidney Transplantation

edited by Sami Alasfar

submission deadline 23 Jan 2025 | 1 articles | Viewed by 1014 | Submission Open

Keywords: rejection; organ optimization; transplantation; immunosuppressants; biomarkers; AI; innovation

(This special issue belongs to the Section Nephrology & Urology)

Rheumatoid Arthritis: Clinical Updates on Diagnosis and Treatment

edited by

Shunsuke Mori

submission deadline 24 Jan 2025 | 5 articles | Viewed by 5341 | Submission Open

Keywords: rheumatoid arthritis; disease-modifying antirheumatic drugs (DMARDs); biological therapies; Janus kinase inhibitors (JAK inhibitors); treatment strategies; joint destruction; comorbidity; drug safety

(This special issue belongs to the Section Immunology)

Future Trends in the Diagnosis and Management of Celiac Disease

edited by

Carolina Ciacci

and

Antonella Santonicola

submission deadline 24 Jan 2025 | 1 articles | Viewed by 1948 | Submission Open

Keywords: celiac disease; gluten; autoimmune disease; extraintestinal manifestations; serologic diagnosis; gluten-free diet

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Outcome and Risk Factors for Thoracic Surgery

edited by

Andrea Dell’Amore

and

Alessio Campisi

submission deadline 24 Jan 2025 | 1 articles | Viewed by 1645 | Submission Open

Keywords: thoracic surgery; ERAS; lung diseases; lung cancer; pulmonary rehabilitation; pharmacological treatments and clinical trials; immunotherapy; minimally invasive surgery; postoperative complication; pulmonary function; preoperative evaluation

(This special issue belongs to the Section General Surgery)

Artificial Intelligence (AI)-Based Diagnosis in Clinical Practice

edited by

Takao Fujisawa

submission deadline 24 Jan 2025 | 1 articles | Viewed by 1297 | Submission Open

Keywords: artificial intelligence; AI; diagnosis; clinical medicine; practice

(This special issue belongs to the Section Epidemiology & Public Health)

Cleft Lip and Palate: Current Treatment and Future Options

edited by Rami S. Kantar

submission deadline 25 Jan 2025 | 8 articles | Viewed by 12775 | Submission Open

Keywords: cleft; cleft lip; cleft palate; cleft surgery; lip; palate; plastic surgery; reconstructive surgery; craniofacial surgery

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Current Perspectives and Future Directions in Oral and Maxillofacial Surgery

edited by Oreste Iocca

submission deadline 25 Jan 2025 | 6 articles | Viewed by 8101 | Submission Open

Keywords: head and neck cancer; maxillofacial trauma; orthognathic surgery; implantology; temporomandibular joint; facial plastic surgery; reconstructive surgery; oncology

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Osteoarticular Infections: New Challenges and Current Concepts in Antibiotic Therapy

edited by

Andreas G. Tsantes

Dimitrios V. Papadopoulos

and

Christos Koutserimpas

submission deadline 25 Jan 2025 | 3 articles | Viewed by 6665 | Submission Open

Keywords: ostoarticular infections; osteomyelitis; septic arthritis; periprosthetic infections; antibiotics; therapy

(This special issue belongs to the Section Orthopedics)

Recent Advances in Acne, Rosacea and Hidradenitis Suppurativa

edited by

Aikaterini I. Liakou

and Alexandros Stratigos

submission deadline 25 Jan 2025 | 2 articles | Viewed by 4104 | Submission Open

Keywords: acne; rosacea; hidradenitis suppurativa; inflammatory skin diseases; papules; pustules; nodules; cysts; scars; topical medications; oral therapies; biological treatments; surgery; laser and light therapy; challenges; diagnosis; treatment; management; challenges

(This special issue belongs to the Section Dermatology)

Cardiac Electrophysiology: New Insights and Future Directions

edited by

Michael Spartalis

submission deadline 25 Jan 2025 | 4 articles | Viewed by 3849 | Submission Open

Keywords: cardiac arrhythmias; atrial fibrillation; ventricular arrhythmias; remote monitoring; implantable cardioverter– defibrillators; cardiac resynchronization therapy; catheter ablation; channelopathies

(This special issue belongs to the Section Cardiology)

Cystic Fibrosis: Clinical Manifestations and Treatment

edited by

Laura Trandafir

and

Lǎcrǎmioara Ionela Butnariu

submission deadline 25 Jan 2025 | 2 articles | Viewed by 2169 | Submission Open

Keywords: cystic fibrosis; modifier genes; CFTR modulator; CF newborn screening; CF nutrition; CF complications

(This special issue belongs to the Section Pulmonology)

Respiratory Cardiology and Cardiopulmonary Rehabilitation: Insights into Cardiovascular and Pulmonary Interactions

edited by

Yoshitaka Iso

and Ssu-Yuan Chen

submission deadline 25 Jan 2025 | 2 articles | Viewed by 2159 | Submission Open

Keywords: cardiovascular diseases; pulmonary circulation; cardiopulmonary rehabilitation; cardiopulmonary exercise testing; lung diseases; venous thromboembolism; cardio-oncology; sleep apnea

(This special issue belongs to the Section Cardiology)

Multidisciplinary Endocarditis Perspectives: 2nd Edition

edited by

Giovanni La Canna

submission deadline 25 Jan 2025 | 1 articles | Viewed by 2086 | Submission Open

Keywords: endocarditis; clinical diagnostic; multimodality imaging; cardiology; clinical phenotypes

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Advances in Hemodialysis

edited by Maurizio Bossola

submission deadline 25 Jan 2025 | 3 articles | Viewed by 2051 | Submission Open

Keywords: hemodialysis; interdialytic weight gain; symptom burden and quality of life; impaired cognitive function; fatigue; dietary restrictions; depression; anxiety; frailty; polypharmacy

(This special issue belongs to the Section Nephrology & Urology)

Recent Advances in Clinical Management of Ischemic Stroke: 2nd Edition

edited by

Laurent Suissa

and

Anthony Faivre

submission deadline 25 Jan 2025 | 1 articles | Viewed by 1453 | Submission Open

Keywords: ischemic stroke; thrombolysis; mechanical thrombectomy; atrial fibrillation; cerebrovascular disorders; stroke; secondary prevention

(This special issue belongs to the Section Clinical Neurology)

Arterial Calcification as a Repair Mechanism in Health and Disease

edited by

Willem P. T. M. Mali

submission deadline 25 Jan 2025 | 1 articles | Viewed by 1253 | Submission Open

Keywords: arterial calcification; repair mechanism; general population; rare diseases; vascular disease

(This special issue belongs to the Section Nuclear Medicine & Radiology)

Female Infertility: Clinical Diagnosis and Treatment

edited by

Laurie Henry

submission deadline 25 Jan 2025 | 1 articles | Viewed by 881 | Submission Open

Keywords: infertility; assisted reproductive techniques; diagnosis; implantation; gametes

(This special issue belongs to the Section Obstetrics & Gynecology)

Multiple Myeloma: Advances in Diagnosis and Treatment

edited by

Martina Kleber

submission deadline 25 Jan 2025 | Viewed by 290 | Submission Open

Keywords: multiple myeloma; early intervention; novel therapies; treatment approach; prognosis; bispecific antibodies; CAR T-cells

(This special issue belongs to the Section Oncology)

Therapeutic Advancements in Psoriasis and Psoriatic Arthritis

edited by

Vincenzo Picone

and

Sara Cacciapuoti

submission deadline 25 Jan 2025 | Viewed by 277 | Submission Open

Keywords: psoriasis; psoriatic arthritis; biologics; small molecules; cytokines

(This special issue belongs to the Section Immunology)

Clinical Updates on Lung Cancer Approaches

edited by

Ramon Andrade De Mello

submission deadline 25 Jan 2025 | Viewed by 239 | Submission Open

Keywords: targeted therapies; immunotherapy; biomarkers; lung cancer; thoracic oncology

(This special issue belongs to the Section Oncology)

Exploring Recent Advancements in Migraine Treatment: Insights from Clinical Neurology

edited by Pablo Irimia and

Dimos-Dimitrios Mitsikostas

submission deadline 26 Jan 2025 | 3 articles | Viewed by 3647 | Submission Open

Keywords: migraine; chronic migraine; treatment; progression; stigma

(This special issue belongs to the Section Clinical Neurology)

New Challenges in Reconstructive Microsurgery: Technological Advances

edited by Giulio Menichini

submission deadline 26 Jan 2025 | 1 articles | Viewed by 1508 | Submission Open

Keywords: microsurgery; robotic-assisted device; outcomes; improvements; technological advances; complications defection

(This special issue belongs to the Section Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine)

Research Progress and Challenges in Acute Abdominal Surgery

edited by Matteo Cimino

submission deadline 26 Jan 2025 | 1 articles | Viewed by 900 | Submission Open

Keywords: acute abdominal emergencies; urgent surgical interventions; minimally invasive techniques; robotic surgery in emergency surgery; open surgery; complications; pain management; postoperative rehabilitation; acute appendicitis; acute biliary disease; intraoperative ultrasonography in emergency surgery

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Corneal and Cataract Surgery: Clinical Updates

edited by

Gracia María Castro de Luna

submission deadline 28 Jan 2025 | 6 articles | Viewed by 8137 | Submission Open

Keywords: cataract surgery; intraocular lens; intraocular lens power calculation; cornea; corneal topography; corneal aberrations; keratoconus; corneal transplant

(This special issue belongs to the Section Ophthalmology)

New Insights into Diabetic Foot

edited by Prashanth Vas and

Marco Meloni

submission deadline 28 Jan 2025 | Viewed by 209 | Submission Open

Keywords: diabetic foot syndrome; diabetic foot infection; diabetic foot osteomyelitis; peripheral arterial disease; ischaemic ulcer; diabetic neuropathy

(This special issue belongs to the Section Endocrinology & Metabolism)

Clinical Consequences of COVID-19: 2nd Edition

edited by

Francesco Alessandri

Francesco Pugliese

and

Giovanni Giordano

submission deadline 30 Jan 2025 | 15 articles | Viewed by 20258 | Submission Open

Keywords: COVID-19; long COVID-19; SARS-CoV-2; mental health; COVID-19 health consequences

(This special issue belongs to the Section Epidemiology & Public Health)

Assisted Reproductive Technology and Infertility Treatment: Current Updates and Perspectives

edited by Nikos Nikolettos and

Angeliki Tiptiri-Kourpeti

submission deadline 30 Jan 2025 | 8 articles | Viewed by 11445 | Submission Open

Keywords: assisted reproduction technology (ART); infertility; treatment; reproduction; IVF

(This special issue belongs to the Section Reproductive Medicine & Andrology)

Physical Therapy in Neurorehabilitation

edited by Marianna Papadopoulou and

George K. Papadimas

submission deadline 30 Jan 2025 | 5 articles | Viewed by 5795 | Submission Open

Keywords: physical therapy; transcutaneous electrical nerve stimulation (TENS); muscle strengthening; balance exercising; pain; quality of life; neurodegenerative disorders; neuromuscular disorders; stroke; demyelinating disorders

(This special issue belongs to the Section Clinical Neurology)

Clinical Challenges in Endocarditis—2nd Edition

edited by

Antonio Salsano

submission deadline 30 Jan 2025 | 5 articles | Viewed by 5174 | Submission Open

Keywords: cardiovascular surgery; infective endocarditis; heart valves pathology; diagnosis; management; therapy

(This special issue belongs to the Section Cardiovascular Medicine)

Clinical Application of Endoscopic Surgery in Gastrointestinal Diseases

edited by Makoto Nishimura and

Hirotsugu Sakamoto

submission deadline 30 Jan 2025 | 1 articles | Viewed by 1049 | Submission Open

Keywords: endoscopy training; GI Fellowship; advanced GI fellowship; mentoring GI training; diagnostic endoscopy training; advanced endoscopy training; AI diagnosis; third space endoscopy training

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Cataract and Refractive Surgery, and Intraocular Lens (IOL) Implantation: Recent Advances and Perspectives

edited by Ehud I. Assia

submission deadline 30 Jan 2025 | 1 articles | Viewed by 851 | Submission Open

Keywords: premium IOLs (multifocal and toric); IOL power calculation; biometry and imaging; complications and management; laser vision correction; phakic IOLs; femtosecond-laser-assisted cataract surgery; AI (artificial intelligence) and cataract/refractive surgery; accommodative lenses

(This special issue belongs to the Section Ophthalmology)

Acute Myocardial Infarction: Clinical Advances in Prognostic Stratification, Diagnosis, and Treatment

edited by

Matteo Armillotta

Luca Bergamaschi

and

Carmine Pizzi

submission deadline 30 Jan 2025 | Viewed by 312 | Submission Open

Keywords: acute myocardial infarction (AMI); atherosclerosis; ST segment elevation myocardial infarction (STEMI); non-ST elevation myocardial infarction (NSTEMI); acute coronary syndrome (ACS); prognosis; coronary CT angiography (CCTA); cardiac magnetic resonance (CMR); reperfusion therapy; antiplatelet therapy

(This special issue belongs to the Section Cardiology)

Spinal Disorders: Current Treatment and Future Opportunities: Part II

edited by

Bassel G. Diebo

and

Alan H Daniels

submission deadline 31 Jan 2025 | 13 articles | Viewed by 22431 | Submission Open

Keywords: spine; spine surgery; spondylolisthesis; scoliosis; cervical myelopathy; spine surgery training; disc replacement; spine trauma; spine infection; spine fracture; spinal epidural abscess

(This special issue belongs to the Section Orthopedics)

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