TSPAN2

Last updated
TSPAN2
Identifiers
Aliases TSPAN2 , NET3, TSN2, TSPAN-2, tetraspanin 2
External IDs OMIM: 613133 MGI: 1917997 HomoloGene: 21169 GeneCards: TSPAN2
Orthologs
SpeciesHumanMouse
Entrez

10100

70747

Ensembl

ENSG00000134198

ENSMUSG00000027858

UniProt

O60636

Q922J6

RefSeq (mRNA)

NM_001308315
NM_001308316
NM_005725

NM_001243132
NM_027533

RefSeq (protein)

NP_001295244
NP_001295245
NP_005716

NP_001230061
NP_081809

Location (UCSC) Chr 1: 115.05 – 115.09 Mb Chr 3: 102.64 – 102.71 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tetraspanin-2 is a protein that in humans is encoded by the TSPAN2 gene. [5] [6] [7]

Contents

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [7]

Related Research Articles

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<span class="mw-page-title-main">TM4SF5</span> Protein-coding gene in the species Homo sapiens

Transmembrane 4 L6 family member 5 is a protein that in humans is encoded by the TM4SF5 gene.

<span class="mw-page-title-main">CNIH</span> Protein-coding gene in the species Homo sapiens

Protein cornichon homolog is a protein that in humans is encoded by the CNIH gene.

<span class="mw-page-title-main">HMGN4</span> Protein-coding gene in the species Homo sapiens

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000134198 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027858 - Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Todd SC, Doctor VS, Levy S (Sep 1998). "Sequences and expression of six new members of the tetraspanin/TM4SF family". Biochim Biophys Acta. 1399 (1): 101–4. doi: 10.1016/s0167-4781(98)00087-6 . PMID   9714763.
  6. ↑ Berditchevski F (Dec 2001). "Complexes of tetraspanins with integrins: more than meets the eye". J Cell Sci. 114 (Pt 23): 4143–51. doi:10.1242/jcs.114.23.4143. PMID   11739647.
  7. 1 2 "Entrez Gene: TSPAN2 tetraspanin 2".

Further reading


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