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Author: Yohn, Samantha E (2)
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28 December 2024






        
        
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American Journal of PsychiatryArticle11 December 2024
The Impact of Xanomeline and Trospium Chloride on Cognitive Impairment in Acute Schizophrenia: Replication in Pooled Data From Two Phase 3 Trials
Objective: Xanomeline and trospium chloride (formerly known as KarXT), a novel M1/M4 muscarinic receptor agonist, demonstrated efficacy across phase 2 and 3 trials as monotherapy for the treatment of inpatients with acute schizophrenia on the Positive and ...
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American Journal of PsychiatryReviews and Overviews27 June 2022
Muscarinic Acetylcholine Receptor Agonists as Novel Treatments for Schizophrenia
Schizophrenia remains a challenging disease to treat effectively with current antipsychotic medications due to their limited efficacy across the entire spectrum of core symptoms as well as their often burdensome side-effect profiles and poor tolerability. ... 
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