CA2184900C - Optical waveguide with flexible tips - Google Patents

Optical waveguide with flexible tips Download PDF

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Publication number
CA2184900C
CA2184900C CA002184900A CA2184900A CA2184900C CA 2184900 C CA2184900 C CA 2184900C CA 002184900 A CA002184900 A CA 002184900A CA 2184900 A CA2184900 A CA 2184900A CA 2184900 C CA2184900 C CA 2184900C
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Canada
Prior art keywords
core
tip
light
distal end
catheter
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Expired - Fee Related
Application number
CA002184900A
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French (fr)
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CA2184900A1 (en
Inventor
Daniel R. Doiron
Hugh L. Narciso, Jr.
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PDT Systems Inc
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PDT Systems Inc
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Publication date
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Priority to CA002184900A priority Critical patent/CA2184900C/en
Priority claimed from PCT/US1993/009656 external-priority patent/WO1995009574A1/en
Publication of CA2184900A1 publication Critical patent/CA2184900A1/en
Application granted granted Critical
Publication of CA2184900C publication Critical patent/CA2184900C/en
Anticipated expiration legal-status Critical
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Laser Surgery Devices (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

A flexible tip (10) for a medical catheter suit- able for the transmission of light and dimensionned to pass through extremely small tubular members is described. The flexible tip, preferably made of optically transparent silicone elastomer (13), is af- fixed to the terminal end of a conventional optical fiber. In a preferred embodiment, the flexible tip comprises a central silicone core (11) surrounded by a cladding (12) having an index of refraction less than that of the core (11), permitting internal reflection. The flexible tip is provided with an outer jacket (13) which serves two purposes: (1) it pro- vides structural integrity for the tip; and (2) it re- inforces the union between the flexible tip and the optical fiber to which it is abutted. The tip (10) en- ables the delivery of a comparable amount of light as a large glass fiber of equal core diameter but pos- sesses much greater flexibility. The tip (10) has the flexibility to be able to enter tortuous tubular mem- bers while retaining the light transmitting capabili- ties of relatively inflexible glass optical waveguides of the same diameter.

Description

wo 95/09571 2 1 ~ 4 9 o o PCT~S93,096~

OPTICAL WAVEGUIDE WITH FLEXIBLE TIPS
2 1. Field of the Invention 3 The invention relates generally to the field of 4 interventional optical catheters and, more specifically, to a flexible terminus or tip for transluminal surgical catheters and 6 the like.
7 2. Prior Art 8 The use of energy delivered from a light source, for g example, a laser, for surgical and industrial applications is well documented. Typically, optical waveguides such as silica 11 optical fibers (alternatively referred to herein as "fiber 12 optics") are used to deliver light energy to internal areas of 13 the human body not readily aCc~cc~ directly by the light source.
14 A growing number of procedures, such as laparoscopic lS cholecystectomy, laparoscopic appendectomy, lithotripsy of 16 calculi of the biliary, salivary and urinary tracts, and a host 17 of other light energy surgeries require flexible fiber optics to 18 access and deliver substantial energy to the treatment sight.
19 Often, fiber optics which are flexible enough to access deep, tortuous internal areas of the body are so small in 21 diameter that they lack the rigidity required to push them 22 through the lumen and/or excessive energy density in the fiber 23 causes damage to the fiber rendering such thin fiber optics 24 impractical. Moreover, transmitting higher powers, on the order of 10 or more watts, is inefficient in small fibers due to W095/0957~ 2 1 8 4 9 00 PCT~S93/096~6 1 the difficulty of coupling. Energy density at the fiber optic 2 tip is the total energy delivered divided by the cross sectional 3 area of the optical fiber.
4 High energy densities cause undesired damage to the tip of the fiber. The solution to this problem, with present 6 technology, is either using larger core diameter optical fibers, 7 which while reducing the energy densi~y, substantially reduces 8 the flexibility (doubling the core size reduces the flexibility 9 fourfold), or using a bundle of small core diameter fiber optics creating a large ~LU~O~ ~ion of dead space- Dead space, as used 11 herein, refers to the portion of the cross sectional area of a 12 fiber optic catheter which does not transmit light energy.
13 Large core fiber optics permit the relatively efficient 14 coupling of energy from an external source into the fiber; even if the source is divergent. This is not true of small core 16 fibers. the coupling efficiency of large cores together with 17 their rigidity enables them to be readily advanced through a 18 straight lumen and conduct a large amount of light energy to the 19 tip. The disadvantage is that the tip lacks the flexibility to follow a tortuous path.
21 With conventional laser catheter tips heat buildup is a 22 significant problem. Sapphire or another expensive heat-stable 23 material is frequently used at the tip of such catheters to 24 prevent heat-induced fracturing and subsequent disintegration.
Laser surgery is conveniently done by using a flexible quartz woss/oss7~ 2 1 8 4 q U O PCT~S93/096~

1 fiber for transmitting the laser energy, usually from a Nd:YAG
2 laser source, to the tissue undergoing treatment. In a typical 3 laser surgery system the end or tip of the silica fiber optic 4 serves as the probe for radiating the tissue to effect incision or coagulation thereof. With some fiber optic tips it is 6 desirable to hold the tip away from direct contact with the 7 tissue to avoid fouling of the fiber and, importantly, to avoid 8 heat damage to the fiber end. Non-contact laser systems g employing a light transmitting member at the output end of the fiber to focus or otherwise alter the radiation characteristics 11 of the fiber have also been ~pG~ed, for example, by Enderly in 12 U.S. Patent 4,273,109, and by Daikuzono in U.S. Patent 4,736,743.
13 Microlenses may also be employed to distribute the light exiting 14 the catheter. The problem with the foregoing termini for laser catheters is that they lack the flexibility to enter small 16 tortuous tubular members such as blood vessels, vas deferens, 17 ureters and so forth.
18 SU~MA~Y OF THE lNv~:Nl~loN
19 It is an object of this invention to provide a minimally invasive medical, light transmitting catheter having the light 21 transmitting capability of a large core conventional silica fiber 22 dimensioned to fit within very small tubular members but having 23 much greater flexibility at the distal end that a comparable 24 silica fiber optic.
It is yet another object of this invention to provide a tip woss/0957~ 2 1 8 4 q 00 PCT~S93/096~6 1 having substantially the same light transmitting capabilities as 2 silica tips having a much larger diameter while exhibiting 3 greater flexibility at the tip than can be achieved with silica.
4 It is still another object of this invention to provide a transluminal catheter for conducting light from a source to a 6 distal target which has the advantages of a large core silica 7 fiber for coupling light from a source into the fiber and 8 permitting advancement of the catheter through the lumen and 9 having a tip which has the flexibility of a small core silica fiber.
11 It is yet another object of this invention to provide a 12 flexible tip for a medical light delivery catheter of a 13 composition amenable to being formed in many different geometries 14 or configurations.
These and other objects of the invention will soon become 16 apparent as we turn now to the descriptions of the preferred 17 embodiment.

19 Figure 1 is a perspective view of the tip of the catheter of the present invention.
21 Figure 2 is a partially cutaway view of the tip of Figure 22 1.
23 Figure 3 is a longitll~; nA 1 cutaway view of the catheter of 24 the present invention with a first preferred embodiment of the tip in place.

woss/0957~ 2 1 8 4 ~ O O PCT~Sg3/096~fi 1 Figure 4 is a longitudinal cutaway view of the catheter of 2 the present invention with a second preferred embodiment of the 3 diffuser tip in place.
4 Figure 5 is another longitudinal, cross sectional view of an embodiment of the catheter of the current invention with the 6 core of the flexible tip spaced from the core of the optical 7 fiber.
8 Figure 6 is the same as Figure 5 except a cladding surrounds 9 the core material of the tip.
Figure 7 is a partially cutaway schematic view of an 11 embodiment of the invention used with a divergent light source.
12 Figure 8 shows the embodiment of Figure 7 with the flexible 13 tip fitted with a terminus configured as (a) a pointed probe, (b) 14 a rounded smooth terminus, and (c) a focusing lens.
DESCRIPTION OF THE PREFERRED EMBODIMENT
16 A flexible tip for use with the invasive catheter of the 17 present invention is shown in Figure 1, generally indicated at 18 10. The central core 11 of the flexible tip 10 is made from an 19 optically transmissive material such as silicone, silicone copolymer, or any variety of elastomers. Surrounding the central 21 core 11 is a cladding layer 12, again fabricated from silicone, 22 silicone copolymer or elastomer. The cladding layer 12 and the 23 core 11 are specifically chosen for their refractive indices.
24 The refractive index of the cladding 12, which may be a length of tubing, is preferably less than the refractive index of the woss/0957~ 2 1 8 4 9 00 PCT~S93/096~

1 core 11. Correctly choosing the refractive indices of the 2 materials will insure total internal reflection of the light 3 energy while also controlling the solid angle of the exiting 4 light energy (not shown). The tip 10 shown in Figure 1 is abutted to a single fiber (not shown) or fiber bundle (not shown) 6 to receive the light from the optical fiber(s) (not shown) and 7 ultimately to deliver the light energy to the treatment site.
8 The tip core 11 and the cladding 12 are held in position relative g to the fiber optic (not shown) by a structural tube 13 made with flexible elastomeric material such as Teflon~ or polyurethane.

12 Figure 2 is a cut away view of the tip of Figure 1. It is 13 clear that the optically transmissive tip core 11 is suLLouded 14 by a cladding layer 12 which in turn is ~LLoul.ded by a structural tube 13 made of flexible elastomeric material. The 16 outer tube 13 may, of course, be made from a variety of flexible 17 elastomers including Teflon~ and polyethylene. The catheter of 18 the present invention, showing the flexible tip abutted to the 19 terminus of the fiber optic is shown in Figure 3. The catheter, generally indicated at numeral 30, has a fiber optic portion 34 21 abutted to the flexible tip portion 10. The fiber optic portion 22 34 of the catheter 30 comprises a fiber central core 31 23 surrounded by a cladding 32. The core 31 and cl~;ng 32 are 24 enclosed in a jacket 33. The distal tip, or terminus, 35 of the optical fiber portion 34 is abutted against the tip core 11 of -woss/0957~ 2 1 8 4 ~ o o PCT~S93~96~6 1 the flexible tip 10. The tip core 11 is surrounded by tip an 2 outer sheath 13. Treatment light (not shown) exits the tip of 3 the catheter 30 in Figure 3 in the forward direction towards the 4 right. The flexible tip 10 may also include a cladding 12 surrounding the tip core 11 as shown in emhoAiment 40 in Figure 6 4.
7 A second preferred embodiment of the catheter of the present 8 is generally indicated at 50 in Figure 5. In this embodiment the 9 distal tip 35 of the optical fiber portion 34 is spaced from the flexible tip core 11 of the tip portion 10 by means of a liquid 11 or gas-filled space 51. The fluid gap 51 allows greater power 12 handling capabilities by substantially reducing the power density 13 of the transmissive core 11/fluid gap 51 interface compared to 14 the transmissive core 11/fiber optic 31 interface. The fluid space 51 may be filled with a gas or a fluid.
16 Figure 6 shows yet another emhoAiment 60 of the catheter 17 shown in Figure 5 except that the flexible tip has a cladding 18 material 12 surrolln~inq the flexible tip core ll of the flexible 19 tip 10.
It is important that the fiber optic core 31 retain its 21 cladding 32 during fabrication of the catheter. If the cladding 22 32 is stripped from around the core 31 of the fiber optic 34, the 23 catheter will be vulnerable to breakage at the point where the 24 cladding has been stripped from the core. The material chosen for the fiber optic core is less elastic of flexible than the W095/0957~ 2 1 8 4 ~ 00 PCT~S93/09656 1 material chosen for the core of the flexible tip.
2 The advantage of combining a large core silica fiber with 3 an elastomer tip is seen by looking now to Figure 7. Divergent 4 light 70 from a divergent source such as a diode laser 71 readily enters the large core 75 of the silica fiber 72 which conducts 6 the light to the core 78 of the flexible elastomeric tip 74.
7 optically transparent silicone rubber is preferably employed as 8 a material of choice for the tip 74 due to its biocompatibility.
g The index of refraction of the material comprising the flexible tip 74 is preferably close to that of the core 75 of the fiber 11 optic. Alternatively, the space 51 in the embodiment shown in 12 Figures 5 and 6 may be filled with a optically transparent 13 material having an index of refraction between the index of the 14 tip core 74 and the fiber core 75. The relative stiffness of the large diameter silica core 75, enh~ceA by the presence of 16 cladding jacket 76 and outer sheath 77, permits advancement of 17 the catheter through constricted tubular tissue but has a large 18 minimum radius of curvature A. The silicone core tip 74, being 19 relatively short compared to the silica core fiber optic 72 portion, is pushed ahead of the fiber portion 72 during 21 advancement. The silicone core tip, being more flexible, has a 22 much smaller minimum radius curvature, shown at B in Figure 7, 23 enabling it to track sharp turns, guiding the silicone core 24 portion 72 during advancement. The silicone core tip 74 and the silica core 75 of the fiber optic portion 72 of the waveguide wo 9s/09s7~ 2 1 8 4 9 00 PCT~S93109656 1 form a high coupling efficiency union 73. This union 73 can 2 conveniently be made by ext~nAing the sheath (not shown) surround 3 the silica core portion beyond the silica core portion and 4 filling the sheath with uncured silicone followed by curing.
Figure 8 shows the emh~iment of the flexible tipped 6 waveguide of Figure 7 with a variety of flexible tip terminus 7 configurations. Since the flexible tip 74 is elastomeric, it 8 readily bonds to various other plastics. Figure 8(a) shows the 9 flexible tip 74 with a pointed terminus 81 suitable for interstitial use. A rounded or beveled terminus 82 (Figure 8(b) 11 is useful for intraluminal use. Figure 8(c) shows a focusing 12 lens 83 affixed to the flexible tip 74. The termini 81-83 may 13 be fabricated from any transparent material or they may be opaque 14 if the light reaching the flexible tip 74 tip need not exit the tip in the forward direction.
16 It will be appreciated that, while a preferred emho~iment 17 of the invention has been described herein, various modifications 18 will suggest themselves to those skilled in the art. For 19 example, variations in materials may be required for certain industrial applications. The essential feature of the invention 21 is the placement of a flexible tip on a relatively rigid, large 22 core optical fiber to confer the advantages of both materials to 23 a combination product while minimizing their disadvantages.
24 Rigid, large core fibers having relatively inflexible cores comprising a transparent material other than silica such as a wogs/09571 2 1 8 4 9 ~ PCT~S93/09656 1 plastic may be used. Flexible elastomers other than silicone may 2 also be used for the tip. These and other modifications that may 3 suggest themselves to those skilled in the art are considered to 4 be within the spirit and scope of the present invention as set forth in the following claims.

Claims (11)

What I claim is:
1. An optical waveguide for conducting light from a light source to a target, said waveguide comprising:
(a) a fiber optic portion having a proximal and a distal end and a first light conducting core consisting of a first core material coextensive with said fiber optic portion; and (b) a tip portion comprising a light conducting second core having a proximal and distal end, the proximal end of said second core being in optical communication with the distal end of said first core and wherein the second core material is more flexible than said first core material.
2. A medical catheter for coveying light energy from a source of said light energy to a tissue undergoing light treatment, the catheter comprising:
(a) a fiber optic portion having a proximal and distal end and a light transmitting first core coextensive therewith; and (b) a tip portion, said tip portion comprising a light-transmitting second core having a proximal and distal end, said second core consisting of a substantially transparent elastomer having a flexibility greater than said first core, the proximal end of said second core being in optical communication with said distal end of said first core, and wherein said proximal end of said tip portion is affixed to the distal end of said optical fiber portion of said catheter.
3. The medical catheter of Claim 2 further comprising an outer sheath surrounding said second core.
4. The medical catheter of Claim 3 further comprising a layer of cladding interposed between said elastomeric second core and said outer sheath.
5. The medical catheter of Claim 4 wherein said cladding consists of silicone elastomer.
6. The medical catheter of Claim 2 wherein said elastomer comprises optically transparent silicone.
7. The optical waveguide of claim 2 further comprising a pointed terminus, affixed to said distal end of said tip portion.
8. The optical waveguide of claim 2 further comprising a rounded terminus affixed to said distal end of said tip portion.
9. The optical waveguide of claim 2 further comprising a focusing lens affixed to the distal end of said tip portion.
10. A medical catheter for conveying light energy from a source of said light energy to a tissue undergoing light treatment, the catheter comprising:
(a) a fiber optic portion having a proximal and distal end and a light transmitting first core coextensive with said fiber optic portion; and (b) a tip portion comprising a light-transmitting second core consisting of a substantially transparent elastomer having a proximal and distal end, said proximal end of second core being in optical communication with said distal end of said first core, and wherein a space is interposed between said proximal end of said tip portion and the distal end of said optical fiber portion of said catheter.
11. The medical catheter of claim 10 wherein said space is filled with a material having an index of refraction intermediate to the index of refraction of said first and second cores.
CA002184900A 1993-10-07 1993-10-07 Optical waveguide with flexible tips Expired - Fee Related CA2184900C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA002184900A CA2184900C (en) 1993-10-07 1993-10-07 Optical waveguide with flexible tips

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1993/009656 WO1995009574A1 (en) 1992-09-01 1993-10-07 Optical waveguide with flexible tips
CA002184900A CA2184900C (en) 1993-10-07 1993-10-07 Optical waveguide with flexible tips

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CA2184900A1 CA2184900A1 (en) 1995-04-13
CA2184900C true CA2184900C (en) 2003-12-30

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