Racemorphan: Difference between revisions
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'''Racemorphan''', or '''morphanol''', is the [[racemic mixture]] of the two [[stereoisomer]]s of 17-methylmorphinan-3-ol, each with differing [[pharmacology]] and [[therapeutic effect|effect]]s: |
'''Racemorphan''', or '''morphanol''', is the [[racemic mixture]] of the two [[stereoisomer]]s of 17-methylmorphinan-3-ol, each with differing [[pharmacology]] and [[therapeutic effect|effect]]s: |
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* [[Dextrorphan]] |
* [[Dextrorphan]]{{snd}} an [[antitussive]] and [[dissociative drug|dissociative]] [[hallucinogen]] ([[NMDA receptor antagonist]]) |
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* [[Levorphanol]] |
* [[Levorphanol]]{{snd}} an [[opioid]] [[analgesic]] |
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Racemorphan itself is under international control per the Single Convention on Narcotic Drugs 1961 and is therefore listed as a Schedule II Narcotic controlled substance in the US Controlled Substances Act 1970; it has an ACSCN of 9733 and in 2014 it had an aggregate annual manufacturing quota of zero. <ref>{{cite web|url=http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html|title=Conversion Factors for Controlled Substances|website=www.deadiversion.usdoj.gov}}</ref> The salts in use are hydrobromide (free base conversion ratio 0.741), hydrochloride (0.876), and tartrate (0.632). |
Racemorphan itself is under international control per the Single Convention on Narcotic Drugs 1961 and is therefore listed as a Schedule II Narcotic controlled substance in the US Controlled Substances Act 1970; it has an ACSCN of 9733 and in 2014 it had an aggregate annual manufacturing quota of zero. <ref>{{cite web|url=http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html|title=Conversion Factors for Controlled Substances|website=www.deadiversion.usdoj.gov}}</ref> The salts in use are hydrobromide (free base conversion ratio 0.741), hydrochloride (0.876), and tartrate (0.632). |
Latest revision as of 00:30, 26 March 2024
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Identifiers | |
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CAS Number | |
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ChEMBL | |
ECHA InfoCard | 100.005.499 |
Chemical and physical data | |
Formula | C17H23NO |
Molar mass | 257.377 g·mol−1 |
3D model (JSmol) | |
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Racemorphan, or morphanol, is the racemic mixture of the two stereoisomers of 17-methylmorphinan-3-ol, each with differing pharmacology and effects:
- Dextrorphan – an antitussive and dissociative hallucinogen (NMDA receptor antagonist)
- Levorphanol – an opioid analgesic
Racemorphan itself is under international control per the Single Convention on Narcotic Drugs 1961 and is therefore listed as a Schedule II Narcotic controlled substance in the US Controlled Substances Act 1970; it has an ACSCN of 9733 and in 2014 it had an aggregate annual manufacturing quota of zero. [2] The salts in use are hydrobromide (free base conversion ratio 0.741), hydrochloride (0.876), and tartrate (0.632).
See also
[edit]See also
[edit]- Cough syrup
- Noscapine
- Codeine; Pholcodine
- Dextromethorphan; Dimemorfan
- Dextrorphan; Levorphanol
- Butamirate
- Pentoxyverine
- Tipepidine
- Cloperastine
- Levocloperastine
References
[edit]- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). Diário Oficial da União (published 2023-04-04). Archived from the original on 2023-08-03. Retrieved 2023-08-16.
- ^ "Conversion Factors for Controlled Substances". www.deadiversion.usdoj.gov.
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