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依哌唑胺

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依哌唑胺
Skeletal formula of eperezolid
Space-filling model of the eperezolid molecule
臨床資料
ATC碼
  • 未分配
识别信息
  • (S)-N-[[3-[3-Fluoro-4-[4-(2-hydroxyacetyl)piperazin-
    1-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
CAS号165800-04-4  checkY
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C18H23FN4O5
摩尔质量394.40
3D模型(JSmol英语JSmol
  • CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCN(CC3)C(=O)CO)F
  • InChI=1S/C18H23FN4O5/c1-12(25)20-9-14-10-23(18(27)28-14)13-2-3-16(15(19)8-13)21-4-6-22(7-5-21)17(26)11-24/h2-3,8,14,24H,4-7,9-11H2,1H3,(H,20,25)/t14-/m0/s1 ☒N
  • Key:SIMWTRCFFSTNMG-AWEZNQCLSA-N ☒N

依哌唑胺(英語:Eperezolid)是一种噁唑烷酮抗生素

合成

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依哌唑胺的合成[1]

另见

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参考文献

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  1. ^ Brickner, S. J.; Hutchinson, D. K.; Barbachyn, M. R.; Manninen, P. R.; Ulanowicz, D. A.; Garmon, S. A.; Grega, K. C.; Hendges, S. K.; Toops, D. S.; Ford, C. W.; Zurenko, G. E. Synthesis and Antibacterial Activity of U-100592 and U-100766, Two Oxazolidinone Antibacterial Agents for the Potential Treatment of Multidrug-Resistant Gram-Positive Bacterial Infections. Journal of Medicinal Chemistry. 1996, 39 (3): 673–9. PMID 8576909. doi:10.1021/jm9509556.