SPR1A

SPR1A
식별자
에일리어스	SPRR1A, SPRK, 소프롤린 리치 단백질 1A
외부 ID	OMIM : 182265 MGI : 106660 HomoloGene : 105698 Gene Card : SPRR1A
유전자 위치(인간)
크르.	1번 염색체(인간)
끝.	152,985,814 bp
유전자 위치(마우스)
크르.	3번 염색체(마우스)
끝.	92,393,194 bp
RNA발현패턴
	상단 표시 위치:
	잇몸; ; 설체; ; 인간의 음경; ; 구강; ; 외음부; ; 양수; ; 혀 윗면; ; 복부 피부; ; 니플; ; 치주 섬유;
	추가 참조 표현식 데이터
	; ;
	추가 참조 표현식 데이터
유전자 존재론
분자 함수	단백질 고분자 어댑터 활성; GO:0001948 단백질 결합; 구조 분자 활성; 피부 표피의 구조 성분;
셀룰러 컴포넌트	세포질; 각질 봉투; 세포;
생물학적 과정	펩티드 가교체; 케라티네이션; 각질세포분화; 표피 발달; 옥수수화;
	출처:아미고 / QuickGO
맞춤법
	6698
	20753
	ENSG00000169474
	ENSMUSG000050359
	P35321
	Q62266
	NM_005987; NM_001199828
	NM_009264
	NP_001186757; NP_005978
	NP_033290
	위키데이터
인간 보기/편집	마우스 표시/편집

코르니핀A는 SPRR1A ^[5]^[6]유전자에 의해 인간에게 암호화되는 단백질이다.

레퍼런스

^ ^a ^b ^c GRCh38: 앙상블 릴리즈 89: ENSG00000169474 - 앙상블, 2017년 5월
^ ^a ^b ^c GRCm38: 앙상블 릴리즈 89: ENSMUSG000050359 - 앙상블, 2017년 5월
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (June 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins". Genomics. 16 (3): 630–7. doi:10.1006/geno.1993.1240. PMID 8325635.
^ "Entrez Gene: SPRR1A small proline-rich protein 1A".

추가 정보

Greco MA, Lorand L, Lane WS, Baden HP, Parameswaran KN, Kvedar JC (February 1995). "The pancornulins: a group of small proline rich-related cornified envelope precursors with bifunctional capabilities in isopeptide bond formation". The Journal of Investigative Dermatology. 104 (2): 204–10. doi:10.1111/1523-1747.ep12612759. PMID 7829876.
Robinson PA, Marley JJ, High AS, Hume WJ (March 1994). "Differential expression of protease inhibitor and small proline-rich protein genes between normal human oral tissue and odontogenic keratocysts". Archives of Oral Biology. 39 (3): 251–9. doi:10.1016/0003-9969(94)90051-5. PMID 8018055.
Fujimoto W, Nakanishi G, Arata J, Jetten AM (February 1997). "Differential expression of human cornifin alpha and beta in squamous differentiating epithelial tissues and several skin lesions". The Journal of Investigative Dermatology. 108 (2): 200–4. doi:10.1111/1523-1747.ep12334240. PMID 9008234.
Robinson NA, Lapic S, Welter JF, Eckert RL (May 1997). "S100A11, S100A10, annexin I, desmosomal proteins, small proline-rich proteins, plasminogen activator inhibitor-2, and involucrin are components of the cornified envelope of cultured human epidermal keratinocytes". The Journal of Biological Chemistry. 272 (18): 12035–46. doi:10.1074/jbc.272.18.12035. PMID 9115270.
Reddy SP, Konkin T, Wu R (December 1998). "Structure and organization of the genes encoding mouse small proline-rich proteins, mSPRR1A and 1B". Gene. 224 (1–2): 59–66. doi:10.1016/S0378-1119(98)00507-1. PMID 9931436.
Candi E, Tarcsa E, Idler WW, Kartasova T, Marekov LN, Steinert PM (March 1999). "Transglutaminase cross-linking properties of the small proline-rich 1 family of cornified cell envelope proteins. Integration with loricrin". The Journal of Biological Chemistry. 274 (11): 7226–37. doi:10.1074/jbc.274.11.7226. PMID 10066784.
Lee CH, Marekov LN, Kim S, Brahim JS, Park MH, Steinert PM (July 2000). "Small proline-rich protein 1 is the major component of the cell envelope of normal human oral keratinocytes". FEBS Letters. 477 (3): 268–72. doi:10.1016/S0014-5793(00)01806-8. PMID 10908733.
Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Cabral A, Voskamp P, Cleton-Jansen AM, South A, Nizetic D, Backendorf C (June 2001). "Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function". The Journal of Biological Chemistry. 276 (22): 19231–7. doi:10.1074/jbc.M100336200. PMID 11279051.
Bonilla IE, Tanabe K, Strittmatter SM (February 2002). "Small proline-rich repeat protein 1A is expressed by axotomized neurons and promotes axonal outgrowth". The Journal of Neuroscience. 22 (4): 1303–15. doi:10.1523/JNEUROSCI.22-04-01303.2002. PMC 6757578. PMID 11850458.

인간 염색체 1번 유전자에 대한 이 기사는 뭉툭한 것이다.위키피디아를 확장함으로써 위키피디아를 도울 수 있습니다.

[refGRCh38Ensembl-1] GRCh38: 앙상블 릴리즈 89: ENSG00000169474 - 앙상블, 2017년 5월

[refGRCm38Ensembl-2] GRCm38: 앙상블 릴리즈 89: ENSMUSG000050359 - 앙상블, 2017년 5월

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8325635-5] Gibbs S, Fijneman R, Wiegant J, van Kessel AG, van De Putte P, Backendorf C (June 1993). "Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins". Genomics. 16 (3): 630–7. doi:10.1006/geno.1993.1240. PMID 8325635.

[entrez-6] "Entrez Gene: SPRR1A small proline-rich protein 1A".

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SPR1A

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