Ryanodine receptor 2 (Q3415811)

From Wikidata
Jump to navigation Jump to search
mammalian protein found in Homo sapiens
  • cardiac muscle ryanodine receptor-calcium release channel
  • cardiac-type ryanodine receptor
  • ryanodine receptor 2
  • kidney-type ryanodine receptor
  • ryanodine receptor 2 (cardiac)
  • type 2 ryanodine receptor
  • Cardiac muscle ryanodine receptor
  • RYR2
  • islet-type ryanodine receptor
edit
Language Label Description Also known as
English
Ryanodine receptor 2
mammalian protein found in Homo sapiens
  • cardiac muscle ryanodine receptor-calcium release channel
  • cardiac-type ryanodine receptor
  • ryanodine receptor 2
  • kidney-type ryanodine receptor
  • ryanodine receptor 2 (cardiac)
  • type 2 ryanodine receptor
  • Cardiac muscle ryanodine receptor
  • RYR2
  • islet-type ryanodine receptor

Statements

part of
molecular function
protein binding
determination method or standard
IPI
7 references
retrieved
8 April 2019
stated in
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
In cardiomyocytes, binding of unzipping peptide activates ryanodine receptor 2 and reciprocally inhibits calmodulin binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
A comprehensive resource of interacting protein regions for refining human transcription factor networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
FKBP binding characteristics of cardiac microsomes from diverse vertebrates
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
calmodulin binding
determination method or standard
IDA
IEA
IMP
IPI
ISS
8 references
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
ISS
retrieved
8 April 2019
stated in
Mutations in calmodulin cause ventricular tachycardia and sudden cardiac death
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IPI
retrieved
8 April 2019
stated in
Ca(2+)-calmodulin can activate and inactivate cardiac ryanodine receptors
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IEA
retrieved
8 April 2019
stated in
Distinctive malfunctions of calmodulin mutations associated with heart RyR2-mediated arrhythmic disease
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IDA
retrieved
8 April 2019
stated in
FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IDA
retrieved
8 April 2019
stated in
Novel CPVT-Associated Calmodulin Mutation in CALM3 (CALM3-A103V) Activates Arrhythmogenic Ca Waves and Sparks
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IDA
ryanodine-sensitive calcium-release channel activity
determination method or standard
IBA
IDA
IEA
TAS
5 references
retrieved
10 September 2018
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92736&geneProductId=UniProtKB:Q92736
determination method or standard
TAS
retrieved
10 September 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92736&geneProductId=UniProtKB:Q92736
determination method or standard
IEA
retrieved
10 September 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92736&geneProductId=UniProtKB:Q92736
determination method or standard
IEA
retrieved
10 September 2018
stated in
Removal of FKBP12.6 does not alter the conductance and activation of the cardiac ryanodine receptor or the susceptibility to stress-induced ventricular arrhythmias
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92736&geneProductId=UniProtKB:Q92736
determination method or standard
IDA
retrieved
10 September 2018
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q92736&geneProductId=UniProtKB:Q92736
determination method or standard
IBA
cell component
sarcoplasmic reticulum membrane
determination method or standard
IBA
IEA
ISS
TAS
6 references
retrieved
8 April 2019
stated in
GOA
curator
Reactome
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
TAS
retrieved
8 April 2019
stated in
New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
TAS
retrieved
8 April 2019
stated in
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
ISS
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q92736
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IEA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q92736
determination method or standard
IBA
biological process
has part(s)

Identifiers

 
edit
    edit
      edit
        edit
          edit
            edit
              edit
                edit
                  edit
                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q3415811&oldid=2161804491"