Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone (Q24313179)

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title

Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone (English)

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cytochrome P450 family 3 subfamily A member 4

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main subject

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cytochrome P450 family 2 subfamily A member 6

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cytochrome P450 family 2 subfamily E member 1

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cytochrome P450 family 1 subfamily A member 2

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cytochrome P450 family 2 subfamily C member 9

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cytochrome P450 family 2 subfamily D member 6

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cytochrome P450 family 2 subfamily B member 6

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cytochrome P450 family 2 subfamily C member 19

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steroid hydroxylase activity

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author

Miia Turpeinen

2

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5

Olavi Pelkonen

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author name string

Tuomas Korhonen

1

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Ari Tolonen

3

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Kari Laine

4

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language of work or name

English

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publication date

15 February 2008

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The Journal of Steroid Biochemistry and Molecular Biology

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published in

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volume

110

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issue

1-2

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page(s)

56-66

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Kinetics of norethindrone in women; I. Radioimmunoassay and concentrations during multiple dosing

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Kinetics of norethindrone in women. II. Single-dose kinetics

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Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations

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The effect of rifampicin on norethisterone pharmacokinetics

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Pharmacokinetics of norethindrone acetate in women

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Intraindividual comparison of pharmacokinetic parameters of d-norgestrel, lynestrenol and cyproterone acetate in 6 women

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7 January 2021

Serum levels and pharmacokinetics of norethisterone after ingestion of lynestrenol: its relation to dose and stage of the menstrual cycle

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Pharmacokinetics, pharmacodynamic and endometrial effects of a single dose of 200 mg norethisterone enanthate

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Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids

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The interaction between St John's wort and an oral contraceptive

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Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

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Cytochrome P450 (CYP) inhibition screening: comparison of three tests

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Classification and pharmacology of progestins

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Cytochrome P-450-linked monooxygenase system and drug-induced spectral interactions in human liver microsomes

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The effects of rifampin and rifabutin on the pharmacokinetics and pharmacodynamics of a combination oral contraceptive

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Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

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Substrate SARs in human P450s

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Gastrointestinal and systemic uptake of bismuth in mice after oral exposure

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Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian populations

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Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers

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Effect of topiramate or carbamazepine on the pharmacokinetics of an oral contraceptive containing norethindrone and ethinyl estradiol in healthy obese and nonobese female subjects

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Identifiers

DOI

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4 January 2020

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