Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties (Q24299572)

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English	Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties	scientific article

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Tumor suppressor Alpha B-crystallin (CRYAB) associates with the cadherin/catenin adherens junction and impairs NPC progression-associated properties (English)

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author name string

Z Huang

1

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Y Cheng

2

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P M Chiu

3

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F M F Cheung

4

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J M Nicholls

5

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D L-W Kwong

6

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A W M Lee

7

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E R Zabarovsky

8

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E J Stanbridge

9

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H L Lung

10

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M L Lung

11

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publication date

9 August 2012

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31

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32

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3709-20

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Convergence of Wnt, beta-catenin, and cadherin pathways

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A functional investigation of tumor suppressor gene activities in a nasopharyngeal carcinoma cell line HONE1 using a monochromosome transfer approach

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Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis

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Interactive sequences in the stress protein and molecular chaperone human alphaB crystallin recognize and modulate the assembly of filaments

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Intercellular junction assembly, dynamics, and homeostasis

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Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.

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Epstein-Barr virus-encoded LMP2A induces an epithelial-mesenchymal transition and increases the number of side population stem-like cancer cells in nasopharyngeal carcinoma

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Molecular and cytogenetic changes involved in the immortalization of nasopharyngeal epithelial cells by telomerase

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Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene

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Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome

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Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion.

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TSLC1 is a tumor suppressor gene associated with metastasis in nasopharyngeal carcinoma

1 reference

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Identification of tumor suppressive activity by irradiation microcell-mediated chromosome transfer and involvement of alpha B-crystallin in nasopharyngeal carcinoma

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alpha-Crystallin localizes to the leading edges of migrating lens epithelial cells

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Analysis of the alphaB-crystallin domain responsible for inhibiting tubulin aggregation

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Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions

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Human cell lines engineered for tetracycline-regulated expression of tumor suppressor candidate genes from a frequently affected chromosomal region, 3p21.

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Emerging roles for p120-catenin in cell adhesion and cancer

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alpha B-crystallin is a cytoplasmic interaction partner of the kidney-specific cadherin-16.

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Tumor suppressor dual-specificity phosphatase 6 (DUSP6) impairs cell invasion and epithelial-mesenchymal transition (EMT)-associated phenotype

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Abrogated expression of DEC1 during oesophageal squamous cell carcinoma progression is age- and family history-related and significantly associated with lymph node metastasis

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Interactions between important regulatory proteins and human alphaB crystallin

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THY1 is a candidate tumour suppressor gene with decreased expression in metastatic nasopharyngeal carcinoma.

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