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The end of 2005 was supposed to mark the achievement of a critical goal in the treatment of HIV in poor countries. The goal hasn't been met, but it is now within sight.
Earth scientists should find better mechanisms to disseminate facts about the risks of natural disasters, to help local populations make the necessary preparations.
Prenatal genetic tests can now check for abnormalities in developing fetuses, but there is still no regulatory framework for them in the United States.
Web tools now allow data sharing and informal debate to take place alongside published papers. But to take full advantage, scientists must embrace a culture of sharing and rethink their vision of databases.
The future of science and technology in Africa depends on the development of mutually supportive networks. Two examples show how imaginative initiatives can be turned into models for others.
Replicating the success of the US Defense Advanced Research Projects Agency (DARPA), in an organization devoted to energy research, will be easier said than done.