Amy gets inadvertently caught in the middle of a fight between Sheldon and Penny over a chair. Leonard tries to add some spice to his long-distance relationship with Priya.
Penny sets up Raj with a deaf friend, not knowing that she's actually a gold digger, and Sheldon decides to let his minor decisions rest on the roll of the dice.
Sheldon takes offense when Leonard wants to attend a party with Wil Wheaton, while Bernadette tries to block Howard's opportunity to go into outer space.
Sheldon tries to get into the spirit of Halloween by trying to scare the guys after they prank him. Leonard seeks Penny's advice when an attractive comic book artist takes an interest in him.
When Stuart asks Amy on a date, Sheldon considers having a more serious relationship with her. Meanwhile, the guys become obsessed with a new card game involving Wild West heroes and witches.
Penny helps Sheldon work on his relationship with Amy when he trivializes one of her accomplishments. Howard is irked by Bernadette's dislike of children.
Leonard and Penny develop a system to ensure their dates go smoothly. Raj finally finds a woman he can talk to - the virtual assistant on his mobile phone.
Leonard signs out of his roommate agreement, reducing himself and Sheldon to mere acquaintances, while Howard tries to think of a cool astronaut nickname for himself.
When the university forces Sheldon to use vacation days, he decides to hang out in Amy's lab. Howard becomes upset when he hears Bernadette wants him to sign a prenuptial agreement.
NASA cancel, and later reinstate Howard's mission into space, coinciding with his wedding. Leonard inadvertently jeopardizes his relationship with Penny.