TUBGCP2

Last updated
TUBGCP2
Identifiers
Aliases TUBGCP2 , GCP-2, GCP2, Grip103, SPBC97, Spc97p, h103p, hGCP2, hSpc97, tubulin gamma complex associated protein 2, ALP4, SPC97, PAMDDFS
External IDs OMIM: 617817 MGI: 1921487 HomoloGene: 55980 GeneCards: TUBGCP2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001256617
NM_001256618
NM_006659

NM_001286007
NM_001286009
NM_001286011
NM_133755

RefSeq (protein)

NP_001243546
NP_001243547
NP_006650

NP_001272936
NP_001272938
NP_001272940
NP_598516

Location (UCSC) Chr 10: 133.28 – 133.32 Mb Chr 7: 139.58 – 139.62 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Gamma-tubulin complex component 2 is a protein that in humans is encoded by the TUBGCP2 gene. [5] [6] It is part of the gamma-tubulin complex, which is required for microtubule nucleation at the centrosome.

Contents

See also

Related Research Articles

<span class="mw-page-title-main">Tubulin</span> Superfamily of proteins that make up microtubules

Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division.

<span class="mw-page-title-main">TUBA1B</span> Protein-coding gene in the species Homo sapiens

Tubulin alpha-1B chain is a protein that in humans is encoded by the TUBA1B gene.

<span class="mw-page-title-main">Tubulin beta-4B chain</span> Protein-coding gene in the species Homo sapiens

Tubulin beta-4B chain formerly known as tubulin beta-2C chain is a protein that in humans is encoded by the TUBB4B gene.

<span class="mw-page-title-main">PFDN1</span> Protein-coding gene in the species Homo sapiens

Prefoldin subunit 1 is a protein that in humans is encoded by the PFDN1 gene.

<span class="mw-page-title-main">TUBA8</span> Protein-coding gene in the species Homo sapiens

Tubulin alpha-8 chain is a protein that in humans is encoded by the TUBA8 gene.

<span class="mw-page-title-main">TUBA1C</span> Protein-coding gene in the species Homo sapiens

Tubulin alpha-1C chain is a protein that in humans is encoded by the TUBA1C gene.

<span class="mw-page-title-main">TBCB</span> Protein-coding gene in the species Homo sapiens

Tubulin-folding cofactor B is a protein that in humans is encoded by the TBCB gene.

<span class="mw-page-title-main">TUBG2</span> Protein-coding gene in the species Homo sapiens

Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene.

<span class="mw-page-title-main">TUBGCP3</span> Protein-coding gene in the species Homo sapiens

Gamma-tubulin complex component 3 is a protein that in humans is encoded by the TUBGCP3 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

<span class="mw-page-title-main">TUBGCP5</span> Protein-coding gene in the species Homo sapiens

Gamma-tubulin complex component 5 is a protein that in humans is encoded by the TUBGCP5 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

<span class="mw-page-title-main">CEP70</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 70 kDa is a protein that in humans is encoded by the CEP70 gene. The protein interacts with γ-tubulin through its coiled coil domains to localize at the centrosome. CEP70 is involved in organizing microtubules in interphase cells and is required for proper organization and orientation of the mitotic spindle.

<span class="mw-page-title-main">TUBGCP6</span> Protein-coding gene in the species Homo sapiens

Gamma-tubulin complex component 6 is a protein that in humans is encoded by the TUBGCP6 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

<span class="mw-page-title-main">NEDD1</span> Protein-coding gene in the species Homo sapiens

Neural precursor cell expressed, developmentally down-regulated 1, also known as Nedd1, is a human gene and encodes the protein NEDD1.

<span class="mw-page-title-main">Dystrobrevin beta</span> Protein-coding gene in the species Homo sapiens

Dystrobrevin beta is a protein which in humans is encoded by the DTNB gene.

<span class="mw-page-title-main">CEP192</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 192 kDa, also known as Cep192, is a protein that in humans is encoded by the CEP192 gene. It is the homolog of the C. elegans and D. melanogaster gene SPD-2.

<span class="mw-page-title-main">CEP164</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 164 kDa, also known as CEP164, is a protein that in humans is encoded by the CEP164 gene. Its function appears two be twofold: CEP164 is required for primary cilium formation. Furthermore, it is an important component in the response to DNA damage by UV light.

<span class="mw-page-title-main">CEP76</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 76 kDa, also known as CEP76, is a protein that in humans is encoded by the CEP76 gene.

<span class="mw-page-title-main">CEP78</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 78 kDa, also known as Cep78, is a protein that in humans is encoded by the CEP78 gene.

<span class="mw-page-title-main">CEP152</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 152 kDa, also known as Cep152, is a protein that in humans is encoded by the CEP152 gene. It is the ortholog of the Drosophila melanogaster gene asterless (asl) and both are required for centriole duplication.

<span class="mw-page-title-main">TUBGCP4</span> Protein-coding gene in the species Homo sapiens

Tubulin, gamma complex associated protein 4 is a protein in humans that is encoded by the TUBGCP4 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000130640 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025474 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Murphy SM, Urbani L, Stearns T (Jun 1998). "The Mammalian γ-Tubulin Complex Contains Homologues of the Yeast Spindle Pole Body Components Spc97p and Spc98p". J Cell Biol. 141 (3): 663–74. doi:10.1083/jcb.141.3.663. PMC   2132743 . PMID   9566967.
  6. "Entrez Gene: TUBGCP2 tubulin, gamma complex associated protein 2".

Further reading