STYK1

STYK1
Identifiers
Aliases	STYK1 , NOK, SuRTK106, serine/threonine/tyrosine kinase 1
External IDs	OMIM: 611433 MGI: 2141396 HomoloGene: 49545 GeneCards: STYK1
Gene location (Human)
Chr.	Chromosome 12 (human)
End	10,674,318 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	131,353,597 bp
RNA expression pattern
	; ;
	More reference expression data
Gene ontology
Molecular function	• transferase activity ; • nucleotide binding ; • protein kinase activity ; • protein tyrosine kinase activity ; • receptor binding ; • non-membrane spanning protein tyrosine kinase activity ; • GO:0001948 protein binding ; • ATP binding ; • kinase activity ;
Cellular component	• integral component of membrane ; • extrinsic component of cytoplasmic side of plasma membrane ; • cell membrane ; • membrane ;
Biological process	• peptidyl-tyrosine autophosphorylation ; • cell differentiation ; • protein phosphorylation ; • innate immune system ; • cell migration ; • regulation of cell proliferation ; • phosphorylation ; • chemotaxis ; • cell adhesion ; • epidermal growth factor receptor signaling pathway ; • regulation of mast cell degranulation ; • peptidyl-tyrosine phosphorylation ;
	Sources:Amigo / QuickGO
Orthologs
	55359
	243659
	ENSG00000060140
	ENSMUSG00000032899
	Q6J9G0
	Q6J9G1
	NM_018423
	NM_172891
	NP_060893
	NP_766479
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 08, 2020

Tyrosine-protein kinase STYK1 is an enzyme that in humans is encoded by the STYK1 gene.^[5]^[6]

Related Research Articles

Sodium-coupled neutral amino acid transporter 3 is a protein that in humans is encoded by the SLC38A3 gene.

NUAK family SNF1-like kinase 2 also known as SNF1/AMP kinase-related kinase (SNARK) is an enzyme that in humans is encoded by the NUAK2 gene.

Ras-related protein Rab-39B is a protein that in humans is encoded by the RAB39B gene.

DCN1-like protein 4 is a protein that in humans is encoded by the DCUN1D4 gene.

AP-1 complex-associated regulatory protein is a protein that in humans is encoded by the AP1AR gene.

TEX35 is a protein that in humans is encoded by the TEX35 gene.

SPATS2-like protein or DNAPTP6 is a protein that in humans is encoded by the SPATS2L gene.

Ectoderm-neural cortex protein 2 is a protein that in humans is encoded by the KLHL25 gene.

Cysteine-rich secretory protein LCCL domain-containing 2 is a cysteine-rich secretory protein that in humans is encoded by the CRISPLD2 gene.

Serine/threonine-protein kinase 40 is an enzyme that in humans is encoded by the STK40 gene.

Pterin-4-alpha-carbinolamine dehydratase 2 is an enzyme that in humans is encoded by the PCBD2 gene.

Polycomb group RING finger protein 5 is a protein that in humans is encoded by the PCGF5 gene.

Solute carrier family 25 member 39 is a protein that in humans is encoded by the SLC25A39 gene.

Tudor domain-containing protein 3 is a protein that in humans is encoded by the TDRD3 gene. It contains a Tudor domain and UBA protein domain and has three distinct Protein isoforms.

Probable ATP-dependent RNA helicase DDX59 is an enzyme that in humans is encoded by the DDX59 gene.

THAP domain-containing protein 2 is a protein that in humans is encoded by the THAP2 gene.

Coiled-coil domain-containing protein 3 is a protein that in humans is encoded by the CCDC3 gene.

UPF0528 protein FAM172A is a protein that in humans is encoded by the FAM172A gene.

Transmembrane protein 117 is a protein that in humans is encoded by the TMEM117 gene.

NudC domain-containing protein 2 is a protein that in humans is encoded by the NUDCD2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000060140 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032899 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ye X, Ji C, Huang Q, Cheng C, Tang R, Xu J, Zeng L, Dai J, Wu Q, Gu S, Xie Y, Mao Y (Jul 2003). "Isolation and characterization of a human putative receptor protein kinase cDNA STYK1". Mol Biol Rep. 30 (2): 91–6. doi:10.1023/A:1023934017174. PMID 12841579. S2CID 29762417.
↑ "Entrez Gene: STYK1 serine/threonine/tyrosine kinase 1".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932.
Liu L, Yu XZ, Li TS, et al. (2004). "A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice". Cancer Res. 64 (10): 3491–9. doi: 10.1158/0008-5472.CAN-03-2106 . PMID 15150103.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Amachika T, Kobayashi D, Moriai R, et al. (2007). "Diagnostic relevance of overexpressed mRNA of novel oncogene with kinase-domain (NOK) in lung cancers". Lung Cancer. 56 (3): 337–40. doi:10.1016/j.lungcan.2007.01.002. PMID 17298854.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000060140 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032899 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12841579-5] Ye X, Ji C, Huang Q, Cheng C, Tang R, Xu J, Zeng L, Dai J, Wu Q, Gu S, Xie Y, Mao Y (Jul 2003). "Isolation and characterization of a human putative receptor protein kinase cDNA STYK1". Mol Biol Rep. 30 (2): 91–6. doi:10.1023/A:1023934017174. PMID 12841579. S2CID 29762417.

[entrez-6] "Entrez Gene: STYK1 serine/threonine/tyrosine kinase 1".

[1]

[2]

[3]

[4]

[5]

[6]

STYK1

Related Research Articles

References

Further reading