The 2010 season was the Arizona Cardinals' 91st in the National Football League (NFL) and their 23rd in Arizona. The Cardinals attempted to improve on their 10–6 record from 2009. But after a modest 3–2 start, the Cardinals fell apart by losing 9 of their remaining 11 contests. They were eliminated from postseason contention for the first time since 2007 in Week 15.
The 2011 Dallas Cowboys season was the franchise's 52nd season in the National Football League (NFL), the third playing their home games at Cowboys Stadium and the first full season under head coach Jason Garrett. The team improved on their 6–10 record from 2010, but missed the playoffs for the second consecutive season due to their week 17 loss to the eventual Super Bowl champion New York Giants.
The 2012 season was the St. Louis Rams' 75th in the National Football League (NFL), their 18th in St. Louis and their first under head coach Jeff Fisher. Finishing at 7–8–1, they improved on their 2–14 record from 2011. In Week 10 against the San Francisco 49ers, the game ended in a 24–24 tie, the first since the 2008 NFL season. It was Sam Bradford's second and final full season as the Rams starting quarterback as two torn ACLs sidelined him for much of the next season and the entire 2014 season.
The 2012 season was the Arizona Cardinals' 93rd in the National Football League (NFL), their 25th in Arizona, and their sixth and final season under head coach Ken Whisenhunt. After a surprising 4–0 start, which included a major upset of the New England Patriots in week 2, the Cardinals lost 11 of their final 12 games, and missed the playoffs for a third consecutive season, resulting in the firing of head coach Ken Whisenhunt after six seasons. This was Rod Graves' last season as general manager of the Cardinals. A day after the final game of the regular season, he was fired after 6 seasons.
The 2013 Houston Texans season was the franchise's 12th season in the National Football League (NFL). The Texans failed to improve upon their 12–4 record from 2012, suffering through a season-ending 14-game losing streak following a 2–0 start and missing the playoffs for the first time since 2010. Head coach Gary Kubiak was fired after eight seasons following their eleventh loss. Defensive coordinator Wade Phillips was named the interim head coach for the final three games of the season. Out of the 14 games lose by the Texans this year, 9 of them were by one score, marking a record amount of one score losses for the franchise. Their 14-game losing streak is the worst in team history. Coming off a franchise-best 12–4 record just the year before, the Texans tie a league record with the Houston Oilers for the biggest season-to-season decline in win total. On January 3, 2014, claiming that "I'm ready to kick 2013 the hell out the door", Texans owner Robert McNair announced that former Penn State head coach Bill O'Brien would be the Texans' third head coach.
The 2013 season was the Arizona Cardinals' 94th in the National Football League (NFL), their 26th in Arizona and their first under head coach Bruce Arians. The team finished with a 10–6 record, which was the second time in 37 years that the team finished with at least 10 wins. The Cardinals doubled their win total from 2012, and were in playoff contention heading into the Week 17 regular season finale, but missed the playoffs for a fourth consecutive season.
The 2013 season was the St. Louis Rams' 76th in the National Football League (NFL), their 19th in St. Louis and their second under head coach Jeff Fisher. The Rams equaled their win total from 2012, but missed the playoffs for a ninth consecutive season.
The 2014 season was the Arizona Cardinals' 95th in the National Football League (NFL), their 27th in Arizona and their second under head coach Bruce Arians. Following an explosive 9–1 start to the regular season, they finished at 11–5, achieving their highest win total since 1975 when they were still in St. Louis. The Cardinals clinched their first playoff berth since 2009, and had a chance to become the first team to try to play the Super Bowl on their own home field, University of Phoenix Stadium. However, after season-ending injuries to Carson Palmer and Drew Stanton, they were forced to start third-string quarterback Ryan Lindley in the wild-card round, losing to the Carolina Panthers, 27–16, which was the first time since 1982 when they were in St. Louis that the Cardinals went one-and-done.
The 2015 season was the Arizona Cardinals' 96th in the National Football League (NFL), their 117th overall, their 28th in Arizona, their 10th playing home games at University of Phoenix Stadium and their third under head coach Bruce Arians. The Cardinals clinched their first NFC West title since 2009, in addition to the first 13-win season in franchise history. They also clinched a first round bye for the first time in franchise history.
The 2015 season was the New Orleans Saints' 49th in the National Football League (NFL), their 40th playing home games at the Mercedes-Benz Superdome and their ninth under head coach Sean Payton. On November 16, 2015, the Saints hired Dennis Allen to replace fired defensive coordinator Rob Ryan. However, the Saints still missed the playoffs for the second consecutive season. The Saints set a new league record for the most passing touchdowns allowed with 45.
The 2016 season was the New Orleans Saints' 50th in the National Football League (NFL), their 41st playing home games at the Mercedes-Benz Superdome, and their 10th under head coach Sean Payton. The Saints matched their 7–9 record from 2014 and 2015, and missed the playoffs for the third year in a row. One highlight from the season includes quarterback Drew Brees' first return to San Diego for the first time since the Chargers released him at the end of the 2005 season, also where Brees played his first five seasons in. This came 10 years after the Chargers released Brees after the Saints' previous regular season meetings with the Chargers were home games for the Saints, and including a 2008 meeting at Wembley Stadium in London, a game which New Orleans was designated as the home team.
The 2016 season was the Arizona Cardinals' 97th in the National Football League (NFL), their 118th overall, their 29th in Arizona, their 11th at University of Phoenix Stadium and their fourth under head coach Bruce Arians.
The 2017 season was the Arizona Cardinals' 98th in the National Football League (NFL), their 30th in Arizona and their 12th at University of Phoenix Stadium. It was also the fifth and final season under head coach Bruce Arians. The Cardinals played one road game in London at Twickenham Stadium against the Los Angeles Rams as one of the NFL London Games. They improved on a 7–8–1 season they had in 2016, finishing 8–8 as they spent most of the season alternating between wins and losses. However, they missed the playoffs for the second straight season.
The 2017 Dallas Cowboys season was the franchise's 58th season in the National Football League (NFL), the ninth playing their home games at AT&T Stadium and the seventh full season under head coach Jason Garrett. It was also the 29th season under owner Jerry Jones.
The 2018 season was the Arizona Cardinals' 99th in the National Football League (NFL), their 31st in Arizona, and their only season under head coach Steve Wilks. During the off-season, State Farm purchased the naming rights to the Cardinals' home stadium and it was renamed from University of Phoenix Stadium to State Farm Stadium. Although former head coach Bruce Arians retired before the season began, he came out of retirement on January 8, 2019 to become the new coach of the Tampa Bay Buccaneers.
The 2019 season was the Arizona Cardinals' 100th in the National Football League (NFL), their 32nd in Arizona and their first under head coach Kliff Kingsbury, following the firing of former head coach Steve Wilks the previous season. During the offseason, the Cardinals' home stadium was renamed from University of Phoenix Stadium to State Farm Stadium. The Cardinals were one of two current teams, along with the Chicago Bears, who were among the 14 charter members of the American Professional Football Association, which later became the NFL, that celebrated its 100th season in 2019.
The 2020 season was the Arizona Cardinals' 101st in the National Football League (NFL), their 33rd in Arizona and their second under head coach Kliff Kingsbury. It was also the first full season since 1971 without the ownership of Bill Bidwill, who died during the 2019 season.
The 2021 season was the Arizona Cardinals' 102nd season in the National Football League (NFL), their 34th in Arizona and their third under head coach Kliff Kingsbury. They improved from their 8–8 season from the previous year with a 23–13 victory over the Seattle Seahawks in Week 11. The Cardinals started 7–0 for the first time in 47 years when they were based in St. Louis. With their week 11 win over their division rivals, the Seattle Seahawks, the Cardinals improved on their record from the previous year and clinched their first winning season since 2015. Despite a loss to the Indianapolis Colts in Week 16, the Cardinals clinched a playoff berth for the first time since 2015 after the Minnesota Vikings lost to the Los Angeles Rams.
The 2022 season was the Arizona Cardinals' 103rd in the National Football League (NFL), their 35th in Arizona, and their fourth and final under head coach Kliff Kingsbury. They attempted to become the third straight team in NFL history to host and win the Super Bowl as that year's Super Bowl was held at State Farm Stadium. However, they failed to improve upon their 11–6 record from the previous year after a Week 11 loss to the San Francisco 49ers and missed the postseason after a Week 15 loss against the Denver Broncos.
The 2023 season was the Arizona Cardinals' 104th season in the National Football League (NFL) and the first under new head coach Jonathan Gannon and general manager Monti Ossenfort. The Cardinals matched their 4–13 record from the previous year after an upset win over the Philadelphia Eagles in Week 17. The team also introduced new uniforms for the first time since the 2005 season.