Etokszolamid
(IUPAC ) ime
6-etoksi-1,3-benzotiazol-2-sulfonamid
Klinički podaci
Identifikatori
CAS broj
452-35-7
ATC kod
nije dodeljen
PubChem [ 1] [ 2] 3295
DrugBank
DB00311
ChemSpider [ 3] 3179
UNII
Z52H4811WX Y
KEGG [ 4] D02441 Y
ChEBI
CHEBI:101096 Y
ChEMBL [ 5] CHEMBL18 Y
Hemijski podaci
Formula
C 9 H 10 N 2 O 3 S 2
Mol. masa
258,319 g /mol
SMILES
eMolekuli PubHem
InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) Y Y
Farmakokinetički podaci
Vezivanje za proteine plazme
~89%
Poluvreme eliminacije
2,5-5,5 sata
Farmakoinformacioni podaci
Trudnoća
?
Pravni status
Etokszolamid ili Etoksizolamid je sulfonamidni lek koji deluje kao inhibitor karbonatne dehidrataze .[ 6] [ 7] glaukoma , čireva dvanaestopalačnog creva , i kao diuretik . On takođe nalazi primenu u tretmanu pojednih formi epilepsije .
↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.” . Drug Discov Today 15 (23-24): 1052-7. DOI :10.1016/j.drudis.2010.10.003 . PMID 20970519 . edit ↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4 : 217-241. DOI :10.1016/S1574-1400(08)00012-1 . ↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining” . J Cheminform 2 (1): 3. DOI :10.1186/1758-2946-2-3 . PMID 20331846 . edit ↑ Joanne Wixon, Douglas Kell (2000). „Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG” . Yeast 17 (1): 48–55. DOI :10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H . ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI :10.1093/nar/gkr777 . PMID 21948594 . edit ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. PMID 21059682 . ↑ Wishart DS, Knox C, Guo AC, Cheng D, Shrivastava S, Tzur D, Gautam B, Hassanali M (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. PMID 18048412 .
