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Benzofuranilpropilaminopentan

Izvor: Wikipedija
(Preusmjereno sa stranice Benzofuranil propilaminopentan)
Benzofuranilpropilaminopentan
(IUPAC) ime
(2R)-1-(1-Benzofuran-2-il)-N-propilpentan-2-amin
Klinički podaci
Identifikatori
CAS broj 260550-89-8
ATC kod nije dodeljen
PubChem[1][2] 9859674
ChemSpider[3] 7992053
Hemijski podaci
Formula C16H23NO 
Mol. masa 245,37
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća ?
Pravni status

(-)-1-(Benzofuran-2-il)-2-propilaminopentan ((-)-BPAP)[4] je lek sa neobičnim profilom dejstva. On se u izvesnoj meri može grupisanti u familje stimulanata i antidepresiva, mada je njegov mehanizam dejstva veoma različit.[5][6]

Reference

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  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. US Patent 6214859
  5. Shimazu S, Takahata K, Katsuki H, Tsunekawa H, Tanigawa A, Yoneda F, Knoll J, Akaike A. (-)-1-(Benzofuran-2-yl)-2-propylaminopentane enhances locomotor activity in rats due to its ability to induce dopamine release. European Journal of Pharmacology. 2001; 421: 181-189.
  6. Shimazu S, Tsunekawa H, Yoneda F, Katsuki H, Akaike A, Janowsky A. Transporter Mediated Actions of R-(-)-1-(Benzofuran-2-yl)-2-propylaminopentane. European Journal of Pharmacology. 2003; 482: 9-16.

Spoljašnje veze

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