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American Journal of PsychiatryArticles15 December 2017

Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group

Premika S.W. Boedhoe, M.Sc.,
Lianne Schmaal, Ph.D.,
Yoshinari Abe, M.D.,
Pino Alonso, M.D., Ph.D.,
Stephanie H. Ameis, M.D., M.Sc.,
Alan Anticevic, Ph.D.,
Paul D. Arnold, M.D., Ph.D.,
Marcelo C. Batistuzzo, Ph.D.,
Francesco Benedetti, M.D.,
Jan C. Beucke, Ph.D.,
Irene Bollettini, Ph.D.,
Anushree Bose, M.A.,
Silvia Brem, Ph.D.,
Anna Calvo, M.Sc.,
Rosa Calvo, M.D., Ph.D.,
Yuqi Cheng, Ph.D.,
Kang Ik K. Cho, Ph.D.,
Valentina Ciullo, Ph.D.,
Sara Dallaspezia, M.D.,
Damiaan Denys, M.D., Ph.D.,
Jamie D. Feusner, M.D.,
Kate D. Fitzgerald, M.D.,
Jean-Paul Fouche, Ph.D.,
Egill A. Fridgeirsson, M.Sc.,
Patricia Gruner, Ph.D.,
Gregory L. Hanna, M.D.,
Derrek P. Hibar, Ph.D.,
Marcelo Q. Hoexter, M.D., Ph.D.,
Hao Hu, Ph.D.,
Chaim Huyser, M.D., Ph.D.,
Neda Jahanshad, Ph.D.,
Anthony James, M.D.,
Norbert Kathmann, Ph.D.,
Christian Kaufmann, Ph.D.,
Kathrin Koch, Ph.D.,
Jun Soo Kwon, M.D., Ph.D.,
Luisa Lazaro, M.D., Ph.D.,
Christine Lochner, Ph.D.,
Rachel Marsh, Ph.D.,
Ignacio Martínez-Zalacaín, M.Sc.,
David Mataix-Cols, Ph.D.,
José M. Menchón, M.D., Ph.D.,
Luciano Minuzzi, M.D., Ph.D.,
Astrid Morer, M.D., Ph.D.,
Takashi Nakamae, M.D., Ph.D.,
Tomohiro Nakao, M.D., Ph.D.,
Janardhanan C. Narayanaswamy, M.D.,
Seiji Nishida, M.D., Ph.D.,
Erika Nurmi, M.D., Ph.D.,
Joseph O’Neill, Ph.D.,
John Piacentini, Ph.D.,
Fabrizio Piras, Ph.D.,
Federica Piras, Ph.D.,
Y.C. Janardhan Reddy, M.D.,
Tim J. Reess, M.A.,
Yuki Sakai, M.D., Ph.D.,
Joao R. Sato, Ph.D.,
H. Blair Simpson, M.D., Ph.D.,
Noam Soreni, M.D.,
Carles Soriano-Mas, Ph.D.,
Gianfranco Spalletta, M.D., Ph.D.,
Michael C. Stevens, Ph.D.,
Philip R. Szeszko, Ph.D.,
David F. Tolin, Ph.D.,
Guido A. van Wingen, Ph.D.,
Ganesan Venkatasubramanian, M.D., Ph.D.,
Susanne Walitza, M.D., M.Sc.,
Zhen Wang, M.D., Ph.D.,
Je-Yeon Yun, M.D., Ph.D.,
ENIGMA-OCD Working Group,
Paul M. Thompson, Ph.D.,
Dan J. Stein, M.D., Ph.D.,
Odile A. van den Heuvel, M.D., Ph.D.,
Premika S.W. Boedhoe,
Lianne Schmaal,
Yoshinari Abe,
Pino Alonso,
Stephanie H. Ameis,
Alan Anticevic,
Paul D. Arnold,
Nuria Bargalló,
Marcelo C. Batistuzzo,
Francesco Benedetti,
Jan C. Beucke,
Irene Bollettini,
Anushree Bose,
Daniel Brandeis,
Silvia Brem,
Elizabeth Buimer,
Geraldo F. Busatto,
Anna Calvo,
Rosa Calvo,
Yuqi Cheng,
Kang Ik K. Cho,
Valentina Ciullo,
Sara Dallaspezia,
Froukje E. de Vries,
Stella J. de Wit,
Damiaan Denys,
Renate Drechsler,
Andrea Falini,
Yu Fang,
Jamie D. Feusner,
Martijn Figee,
Kate D. Fitzgerald,
Martine Fontaine,
Jean-Paul Fouche,
Egill A. Fridgeirsson,
Patricia Gruner,
Gregory L. Hanna,
Tobias U. Hauser,
Derrek P. Hibar,
Marcelo Q. Hoexter,
Hao Hu,
Chaim Huyser,
Mariangela Iorio,
Neda Jahanshad,
Anthony James,
Norbert Kathmann,
Christian Kaufmann,
Sabin Khadka,
Kathrin Koch,
Jun Soo Kwon,
Luisa Lazaro,
Yanni Liu,
Christine Lochner,
Rachel Marsh,
Ignacio Martínez-Zalacaín,
David Mataix-Cols,
James T. McCracken,
José M. Menchón,
Euripedes C. Miguel,
Luciano Minuzzi,
Astrid Morer,
Takashi Nakamae,
Tomohiro Nakao,
Janardhanan C. Narayanaswamy,
Jin Narumoto,
Seiji Nishida,
Erika Nurmi,
Joseph O’Neill,
Jose C. Pariente,
John Piacentini,
Christopher Pittenger,
Fabrizio Piras,
Federica Piras,
Sara Poletti,
Y.C. Janardhan Reddy,
Tim J. Reess,
Oana G. Rus,
Yuki Sakai,
Joao R. Sato,
H. Blair Simpson,
Noam Soreni,
Carles Soriano-Mas,
Gianfranco Spalletta,
Michael C. Stevens,
Philip R. Szeszko,
Jinsong Tang,
David F. Tolin,
Ysbrand D. van der Werf,
Guido A. van Wingen,
Daniela Vecchio,
Dick J. Veltman,
Ganesan Venkatasubramanian,
Susanne Walitza,
Zhen Wang,
Anri Watanabe,
Jian Xu,
Xiufeng Xu,
Kei Yamada,
Je-Yeon Yun,
Mojtaba Zarei,
Qing Zhao,
Paul M. Thompson,
Dan J. Stein, and
Odile A. van den Heuvel

Objective: Brain imaging studies of structural abnormalities in OCD have yielded inconsistent results, partly because of limited statistical power, clinical heterogeneity, and methodological differences. The authors conducted meta- and mega-analyses ...

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Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group

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Cortical Abnormalities Associated With Pediatric and Adult Obsessive-Compulsive Disorder: Findings From the ENIGMA Obsessive-Compulsive Disorder Working Group