Walters et al., 1987 - Google Patents

Purification of a ciliary neurotrophic factor from bovine heart

Walters et al., 1987

Document ID
8181728205156264676
Author
Walters D
Hendry I
Publication year
Publication venue
Journal of neurochemistry

External Links

Snippet

A neurotrophic factor that promotes the survival of cholinergic parasympathetic ciliary neurons has been purified∼ 20,000‐fold from bovine cardiac tissue under nondenaturing conditions using heparin‐affinity chromatography. Up to 22 μg of purified factor having a …
Continue reading at onlinelibrary.wiley.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factors [FGF]
    • C07K14/503—Fibroblast growth factors [FGF] basic FGF [bFGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates

Similar Documents

Publication Publication Date Title
Walters et al. Purification of a ciliary neurotrophic factor from bovine heart
US5441937A (en) Neurotrophic factor
Wagner et al. Neurite outgrowth induced by an endothelial cell mitogen isolated from retina.
Hollenbeck The distribution, abundance and subcellular localization of kinesin.
Moscatelli et al. Both normal and tumor cells produce basic fibroblast growth factor
Manthorpe et al. Purification of adult rat sciatic nerve ciliary neuronotrophic factor
Murphy et al. Secretion of a nerve growth factor by mouse neuroblastoma cells in culture.
Eckenstein et al. Purification and characterization of a trophic factor for embryonic peripheral neurons: comparison with fibroblast growth factors
Manthorpe et al. Laminin promotes neuritic regeneration from cultured peripheral and central neurons.
Hewitt et al. Photoreceptor survival-promoting activity in interphotoreceptor matrix preparations: characterization and partial purification
Shirao et al. Two acidic proteins associated with brain development in chick embryo
Caday et al. Fibroblast growth factor (FGF) levels in the developing rat brain
Longo et al. Nerve growth factor in rat glioma cells
Lindsay et al. Developmentally regulated induction of neurite outgrowth from immature chick sensory neurons (DRG) by homogenates of avian or mammalian heart, liver and brain
Kessler et al. Isolated plasma membranes regulate neurotransmitter expression and facilitate effects of a soluble brain cholinergic factor.
Schubert et al. Isolation of an adhesion-mediating protein from chick neural retina adherons.
Westermann et al. Neuronotrophic factors released by C6 glioma cells
Asai et al. A novel glial growth inhibitory factor, gliostatin, derived from neurofibroma
Hayashi et al. Purification and characterization of a neurite outgrowth factor from chicken gizzard smooth muscle.
Hofmann Ciliary neuronotrophic factor stimulates choline acetyltransferase activity in cultured chicken retina neurons
Manthorpe et al. Cholinergic neuronotrophic factors. Concurrent activities on certain nerve growth factor‐responsive neurons
Ebendal et al. Nerve growth factors in chick and rat tissues
Nishi Target‐derived molecules that influence the development of neurons in the avian ciliary ganglion
Schwartz et al. Factor (s) from goldfish brain induce neuritic outgrowth from explanted regenerating retinas
Bonyhady et al. Reversible dissociation of a bovine cardiac factor that supports survival of avian ciliary ganglionic neurones