Duran-Ortiz et al., 2020 - Google Patents

Tissue-specific disruption of the growth hormone receptor (GHR) in mice: An update

Duran-Ortiz et al., 2020

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Document ID
4939053822859282383
Author
Duran-Ortiz S
Noboa V
Kopchick J
Publication year
Publication venue
Growth Hormone & IGF Research

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The Growth hormone receptor (GHR) is expressed in many cells/tissues in the body. To investigate the specific metabolic effects of GH action in distinct tissues, several tissue- specific GHR gene disrupted or knockout (KO) mouse lines have been generated …
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    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1825—Fibroblast growth factor [FGF]
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    • A61K38/22—Hormones
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