Gu et al., 2018 - Google Patents

Single molecule profiling of molecular recognition at a model electrochemical biosensor

Gu et al., 2018

View PDF
Document ID
2782256582268563490
Author
Gu Q
Nanney W
Cao H
Wang H
Ye T
Publication year
Publication venue
Journal of the American Chemical Society

External Links

Snippet

The spatial arrangement of target and probe molecules on the biosensor is a key aspect of the biointerface structure that ultimately determines the properties of interfacial molecular recognition and the performance of the biosensor. However, the spatial patterns of single …
Continue reading at escholarship.org (PDF) (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay
    • G01N33/543Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the means of detection
    • C12Q1/6825Nucleic acid detection involving sensors

Similar Documents

Publication Publication Date Title
Gu et al. Single molecule profiling of molecular recognition at a model electrochemical biosensor
Josephs et al. Nanoscale spatial distribution of thiolated DNA on model nucleic acid sensor surfaces
Rowe et al. Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences
Du et al. Reagentless, ratiometric electrochemical DNA sensors with improved robustness and reproducibility
Chen et al. Ultrasensitive electrochemical detection of prostate-specific antigen by using antibodies anchored on a DNA nanostructural scaffold
Idili et al. Folding-upon-binding and signal-on electrochemical DNA sensor with high affinity and specificity
White et al. Exploiting binding-induced changes in probe flexibility for the optimization of electrochemical biosensors
Huang et al. Random walk on a leash: a simple single-molecule diffusion model for surface-tethered redox molecules with flexible linkers
Rant et al. Structural properties of oligonucleotide monolayers on gold surfaces probed by fluorescence investigations
Zhou et al. Nanogold-functionalized DNAzyme concatamers with redox-active intercalators for quadruple signal amplification of electrochemical immunoassay
Yang et al. Comparison of the stem-loop and linear probe-based electrochemical DNA sensors by alternating current voltammetry and cyclic voltammetry
Zhang et al. Amperometric aptasensor for amyloid-β oligomer detection by optimized stem-loop structures with an adjustable detection range
Zhang et al. Dual 3D DNA nanomachine-mediated catalytic hairpin assembly for ultrasensitive detection of MicroRNA
Watkins et al. Entropic and electrostatic effects on the folding free energy of a surface-attached biomolecule: an experimental and theoretical study
Uzawa et al. A mechanistic study of electron transfer from the distal termini of electrode-bound, single-stranded DNAs
Lin et al. Photoresponsive electrochemical DNA biosensors achieving various dynamic ranges by using only-one capture probe
Bian et al. An enzyme-free “ON-OFF” electrochemiluminescence biosensor for ultrasensitive detection of PML/RARα based on target-switched DNA nanotweezer
Abel Jr et al. A switchable surface enables visualization of single DNA hybridization events with atomic force microscopy
Choi et al. Detection of silver ions using dielectrophoretic tweezers-based force spectroscopy
Yang et al. Fluorescent nanoparticle beacon for logic gate operation regulated by strand displacement
Su et al. Electrochemical analysis of target-induced hairpin-mediated aptamer sensors
Leung et al. Measuring and controlling the local environment of surface-bound DNA in self-assembled monolayers on gold when prepared using potential-assisted deposition
Veselinovic et al. Anomalous trends in nucleic acid-based electrochemical biosensors with nanoporous gold electrodes
Veselinovic et al. Interplay of effective surface area, mass transport, and electrochemical features in nanoporous nucleic acid sensors
Zanut et al. DNA-Based nanoswitches: insights into electrochemiluminescence signal enhancement