Gu et al., 2018 - Google Patents
Single molecule profiling of molecular recognition at a model electrochemical biosensorGu et al., 2018
View PDF- Document ID
- 2782256582268563490
- Author
- Gu Q
- Nanney W
- Cao H
- Wang H
- Ye T
- Publication year
- Publication venue
- Journal of the American Chemical Society
External Links
Snippet
The spatial arrangement of target and probe molecules on the biosensor is a key aspect of the biointerface structure that ultimately determines the properties of interfacial molecular recognition and the performance of the biosensor. However, the spatial patterns of single …
- 229920003013 deoxyribonucleic acid 0 abstract description 304
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the means of detection
- C12Q1/6825—Nucleic acid detection involving sensors
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Gu et al. | Single molecule profiling of molecular recognition at a model electrochemical biosensor | |
Josephs et al. | Nanoscale spatial distribution of thiolated DNA on model nucleic acid sensor surfaces | |
Rowe et al. | Electrochemical biosensors employing an internal electrode attachment site and achieving reversible, high gain detection of specific nucleic acid sequences | |
Du et al. | Reagentless, ratiometric electrochemical DNA sensors with improved robustness and reproducibility | |
Chen et al. | Ultrasensitive electrochemical detection of prostate-specific antigen by using antibodies anchored on a DNA nanostructural scaffold | |
Idili et al. | Folding-upon-binding and signal-on electrochemical DNA sensor with high affinity and specificity | |
White et al. | Exploiting binding-induced changes in probe flexibility for the optimization of electrochemical biosensors | |
Huang et al. | Random walk on a leash: a simple single-molecule diffusion model for surface-tethered redox molecules with flexible linkers | |
Rant et al. | Structural properties of oligonucleotide monolayers on gold surfaces probed by fluorescence investigations | |
Zhou et al. | Nanogold-functionalized DNAzyme concatamers with redox-active intercalators for quadruple signal amplification of electrochemical immunoassay | |
Yang et al. | Comparison of the stem-loop and linear probe-based electrochemical DNA sensors by alternating current voltammetry and cyclic voltammetry | |
Zhang et al. | Amperometric aptasensor for amyloid-β oligomer detection by optimized stem-loop structures with an adjustable detection range | |
Zhang et al. | Dual 3D DNA nanomachine-mediated catalytic hairpin assembly for ultrasensitive detection of MicroRNA | |
Watkins et al. | Entropic and electrostatic effects on the folding free energy of a surface-attached biomolecule: an experimental and theoretical study | |
Uzawa et al. | A mechanistic study of electron transfer from the distal termini of electrode-bound, single-stranded DNAs | |
Lin et al. | Photoresponsive electrochemical DNA biosensors achieving various dynamic ranges by using only-one capture probe | |
Bian et al. | An enzyme-free “ON-OFF” electrochemiluminescence biosensor for ultrasensitive detection of PML/RARα based on target-switched DNA nanotweezer | |
Abel Jr et al. | A switchable surface enables visualization of single DNA hybridization events with atomic force microscopy | |
Choi et al. | Detection of silver ions using dielectrophoretic tweezers-based force spectroscopy | |
Yang et al. | Fluorescent nanoparticle beacon for logic gate operation regulated by strand displacement | |
Su et al. | Electrochemical analysis of target-induced hairpin-mediated aptamer sensors | |
Leung et al. | Measuring and controlling the local environment of surface-bound DNA in self-assembled monolayers on gold when prepared using potential-assisted deposition | |
Veselinovic et al. | Anomalous trends in nucleic acid-based electrochemical biosensors with nanoporous gold electrodes | |
Veselinovic et al. | Interplay of effective surface area, mass transport, and electrochemical features in nanoporous nucleic acid sensors | |
Zanut et al. | DNA-Based nanoswitches: insights into electrochemiluminescence signal enhancement |