Elmowafy et al., 2019 - Google Patents

Biocompatibility, biodegradation and biomedical applications of poly (lactic acid)/poly (lactic-co-glycolic acid) micro and nanoparticles

Elmowafy et al., 2019

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Document ID
17480516502377627647
Author
Elmowafy E
Tiboni M
Soliman M
Publication year
Publication venue
Journal of Pharmaceutical Investigation

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Background Poly (lactic acid)(PLA) and poly (lactic-co-glycolic acid)(PLGA) are among the well-documented FDA-approved polymers used for the preparation of safe and effective vaccine, drug and gene delivery systems using well-described reproducible methods of …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
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    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61K9/1605—Excipients; Inactive ingredients
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    • A61K47/48884—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a particulate, powder, adsorbate, bead, sphere the form being a solid micro- or nanoparticle having no hollow or gas-filled core the form being a nanoparticle, e.g. an immuno-nanoparticle
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