Rehn, 2011 - Google Patents

THE HYPOXIC HEMATOPOIETIC STEM CELL NICHE Consequences of Hypoxia-induced Transcription on Stem Cell Fate

Rehn, 2011

View PDF
Document ID
17283628886695577552
Author
Rehn M
Publication year

External Links

Snippet

Hematopoiesis is the process of blood formation that originates with the hematopoietic stem cell (HSC), a cell type that is responsible for the life-long supply of mature blood cells. HSCs are defined by their ability to self-renew as well as giving rise to differentiated cells of all …
Continue reading at portal.research.lu.se (PDF) (other versions)

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0647Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027New breeds of vertebrates

Similar Documents

Publication Publication Date Title
Wilkinson et al. Haematopoietic stem cell self-renewal in vivo and ex vivo
Fröbel et al. The hematopoietic bone marrow niche ecosystem
Coşkun et al. Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells
Boulais et al. Making sense of hematopoietic stem cell niches
Dumble et al. The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging
Chen et al. Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells
Boulais et al. The majority of CD45–Ter119–CD31–bone marrow cell fraction is of hematopoietic origin and contains erythroid and lymphoid progenitors
Mazzon et al. The critical role of agrin in the hematopoietic stem cell niche
Chabi et al. Hypoxia regulates lymphoid development of human hematopoietic progenitors
Abidin et al. Frizzled-6 regulates hematopoietic stem/progenitor cell survival and self-renewal
WO2014132032A1 (en) Culture of leukemia initiating cells
Kovacic et al. Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells
Rector et al. Comprehensive hematopoietic stem cell isolation methods
Calés et al. Role of Polycomb RYBP in maintaining the B-1-to-B-2 B-cell lineage switch in adult hematopoiesis
Xu et al. Loss of the Rho GTPase activating protein p190-B enhances hematopoietic stem cell engraftment potential
Eaves et al. Anatomy and physiology of hematopoiesis
Rehn THE HYPOXIC HEMATOPOIETIC STEM CELL NICHE Consequences of Hypoxia-induced Transcription on Stem Cell Fate
Pronk et al. Deciphering developmental stages of adult myelopoiesis
US12129487B2 (en) Method to obtain lymphoid progenitors
Zhao et al. Hematopoietic Stem Cells: Keystone of Tissue Development and Regenerative Medicine
Arcangeli et al. Biology of hematopoietic stem cells in the adult
Rörby Regulation of Hematopoietic Stem Cells
Rydström Hematopoietic stem cell dynamics during regenerative stress
Haddad et al. Biology of Hematopoietic Stem Cells in the Adult
Alzahrani Exploring the role of Zeb1 in the haematopoietic system