Ehrlich et al., 2010 - Google Patents

Exonuclease III action on microarrays: Observation of DNA degradation by fluorescence correlation spectroscopy

Ehrlich et al., 2010

Document ID
12009273408035485405
Author
Ehrlich N
Anhalt K
Hübner C
Brakmann S
Publication year
Publication venue
Analytical biochemistry

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Snippet

DNA with all cytosines, thymines, or all pyrimidines of one strand substituted by fluorescently labeled analogs shows diminished solubility in aqueous media and a strong tendency to aggregation that hampers enzymatic downstream processing. In this study, immobilization of …
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