ZA928776B - Expression of neurotrophic factors with heterologous prepro regions. - Google Patents

Expression of neurotrophic factors with heterologous prepro regions.

Info

Publication number
ZA928776B
ZA928776B ZA928776A ZA928776A ZA928776B ZA 928776 B ZA928776 B ZA 928776B ZA 928776 A ZA928776 A ZA 928776A ZA 928776 A ZA928776 A ZA 928776A ZA 928776 B ZA928776 B ZA 928776B
Authority
ZA
South Africa
Prior art keywords
expression
neurotrophic factors
heterologous prepro
regions
prepro regions
Prior art date
Application number
ZA928776A
Inventor
Stephen P Squinto
Nancy Ip
David Gies
George D Yancopoulos
Shaw-Fen Sylvia Hu
Original Assignee
Regeneron Pharma
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharma, Amgen Inc filed Critical Regeneron Pharma
Publication of ZA928776B publication Critical patent/ZA928776B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA928776A 1991-11-14 1992-11-13 Expression of neurotrophic factors with heterologous prepro regions. ZA928776B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79249291A 1991-11-14 1991-11-14

Publications (1)

Publication Number Publication Date
ZA928776B true ZA928776B (en) 1993-05-13

Family

ID=25157066

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928776A ZA928776B (en) 1991-11-14 1992-11-13 Expression of neurotrophic factors with heterologous prepro regions.

Country Status (7)

Country Link
JP (1) JPH07501220A (en)
CN (1) CN1078493A (en)
AU (1) AU3074992A (en)
IL (1) IL103751A0 (en)
PT (1) PT101064A (en)
WO (1) WO1993010150A1 (en)
ZA (1) ZA928776B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166317A (en) * 1988-10-31 1992-11-24 Houston Biotechnology Incorporated Neurotrophic factor
WO1996008562A1 (en) * 1994-09-12 1996-03-21 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., Berlin Biologically active molecules derived from neurotrophins
AU2800797A (en) 1996-04-05 1997-10-29 Chiron Corporation Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis
CN1104505C (en) * 1996-11-19 2003-04-02 雅玛山酱油株式会社 Process for producing nucelside 5'-triphosphates and application of same
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923808A (en) * 1985-03-12 1990-05-08 Genentech, Inc. Method for identifying mutants secreting high levels of heterologous proteins

Also Published As

Publication number Publication date
JPH07501220A (en) 1995-02-09
PT101064A (en) 1994-02-28
IL103751A0 (en) 1993-04-04
CN1078493A (en) 1993-11-17
WO1993010150A1 (en) 1993-05-27
AU3074992A (en) 1993-06-15

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