KR20160116071A

KR20160116071A - Stent

Info

Publication number: KR20160116071A
Application number: KR1020150041214A
Authority: KR
Inventors: 전용표; 정성민; 정현용; 정인권; 안덕환; 김대은
Original assignee: 주식회사 제노스; 서강대학교산학협력단
Priority date: 2015-03-25
Filing date: 2015-03-25
Publication date: 2016-10-07
Also published as: KR101708859B1; WO2016153293A1

Abstract

According to the present invention, a plurality of struts are arranged in a zigzag arrangement along a circumferential direction to form one cell; And a bridge connecting the one cell and another cell adjacent to the one cell, wherein in each of the one cell and the other cell, the plurality of struts comprises an adjacent pair of struts having a first spacing A first strut pair provided; And a second strut pair having an adjacent pair of struts having a second spacing different from the first spacing.

Description

Stent {STENT}

The present invention relates to a stent used for vasodilation.

In general, complications such as restenosis are recurrent in patients who have been treated for arteriosclerosis in the form of medical procedures such as percutaneous transluminal coronary angioplasty (PTCA).

Restenosis is often treated by a procedure known as stenting. At this time, a medical device is implanted surgically into the involved artery to prevent the vessel from occluding after the procedure.

Stents are typically cylindrical in shape and are made primarily of biocompatible metals such as titanium or surge steel. Most stents are collapsible and delivered to the occluded artery through a catheter.

The stent may be attached to the catheter and expanded by inflation of the balloon within the stent that is self-expanding or removed with the catheter once the device is in place.

It is an object of the present invention to provide a stent capable of uniform expansion when inserted into a blood vessel.

It is another object of the present invention to provide a stent that coordinates the performance in terms of both radial strength and flexibility.

Still another object of the present invention is to provide a stent that can minimize the interference problem between struts.

According to an aspect of the present invention, there is provided a stent comprising: a plurality of struts arranged in a zigzag arrangement along a circumferential direction to form a single cell; And a bridge connecting the one cell and another cell adjacent to the one cell, wherein in each of the one cell and the other cell, the plurality of struts comprises an adjacent pair of struts having a first spacing A first strut pair provided; And a second strut pair having an adjacent pair of struts having a second spacing different from the first spacing.

Here, the first strut pair and the second strut pair may be separately disposed on both sides of the first bridge, which is one of the bridges.

Wherein the first strut pair comprises a first strut and a second strut on one side of the first bridge and a fourth strut and a fifth strut and the second strut pair comprises a first strut and a second strut, The first strut and the second strut, and the fourth strut and the fifth strut.

Here, the bridge may include a second bridge connected to a portion where a fifth strut and a sixth strut meet at one side of the first bridge; And a third bridge connected to a portion where the fifth strut and the sixth strut meet on the other side of the first bridge.

Here, the first bridge may be disposed parallel to the second bridge and the third bridge.

Here, the bridge may be arranged to be inclined with respect to a direction in which the one cell and the other cell are arranged successively.

Here, in the one cell and the other cell, the arrangement of the plurality of struts is the same but may have a phase difference along the circumferential direction.

Here, the phase difference between the one cell and the other cell may correspond to an angle along the circumferential direction between the first bridge and the second bridge.

According to the stent of the present invention configured as described above, the stent inserted into the blood vessel can be uniformly expanded.

According to the above stent, the stent performance in terms of radial strength and flexibility can be coordinated with each other.

According to the above stent, the interference problem between struts is minimized.

1 is a plan view showing a stent 100 according to an embodiment of the present invention.
2 is an enlarged view of a portion of the stent 100 of FIG.
FIG. 3 is an image of an appearance evaluation photograph of a sample produced for the stent 100 of FIG.

Hereinafter, a stent according to a preferred embodiment of the present invention will be described in detail with reference to the accompanying drawings. In the present specification, the same or similar reference numerals are given to different embodiments in the same or similar configurations.

1 is a plan view showing a stent 100 according to an embodiment of the present invention.

The stent 100 may have cells 110-170, struts 210-270, and bridges 310-360.

Each of the cells 110 to 170 is substantially in the form of a ring. By staggering the cells 110 to 170 along the longitudinal direction L, the stent 10 is generally pipe-shaped. The structure of the stent 100 is suitable for being inserted into the blood vessel and used to widen the cross-sectional area of blood flow in the blood vessel.

The struts 210 to 270 are the basic members forming each of the cells 110 to 170. The struts 210 to 270 may be formed in the form of wires made of a biocompatible metal such as titanium or surge steel. The struts 210 to 270 are disposed in a plurality of cells 110 to 170 to form cells 110 to 170, respectively. To this end, the plurality of struts 210 to 270 are arranged in a jig manner along the circumferential direction C of the stent 100.

The bridges 310 to 360 are structures for connecting adjacent ones of the cells 110 to 170. Specifically, the bridges 310 to 360 connect the struts 210 to 270 of the cells 110 to 170 with the adjacent struts 210 to 270 of the cells 110 to 170, respectively.

The specific structure of the stent 100 is described with reference to FIG.

2 is an enlarged view of a portion of the stent 100 of FIG.

In the figure, a second cell 120, a third cell 130, and a fourth cell 140 are illustrated as a plurality of cells 110 to 170 for convenience of explanation.

The strut pattern of one section in the second cell 120 has five struts 221a, 221b, 222, 223a, 223b / 226a, 226b, 227, 228a arranged on both sides with respect to the first bridge 311 , 228b.

At this time, part of the struts 221a, 221b, 222, 223a, 223b on one side of the first bridge 311 are arranged so as to have a first spacing between adjacent struts. On the other hand, some of the struts 226a, 226b, 227, 228a, 228b on the other side of the first bridge 311 are arranged to have a second spacing between adjacent struts. The first spacing may be greater than the second spacing.

Further, adjacent struts having a first spacing may be referred to as a first strut pair. Specifically, the first and second struts 221a and 221b on one side of the first bridge 311 and the fourth and fifth struts 223a and 223b are first strut pairs, respectively.

Similarly, adjacent struts having a second spacing may be referred to as a second strut pair. Specifically, the first and second struts 226a and 226b on the other side of the first bridge 311, and the fourth and fifth struts 228a and 228b, respectively, become a second strut pair.

In the third cell 130, which is another cell adjacent to the second cell 120, a strut pattern of one section in the third cell 130 is divided into five strands each disposed on both sides with respect to the second bridge 322 Struts 231a, 231b, 232, 233a, 223b / 236a, 236b, 237, 238a, 238b.

At this time, the strut pattern in the third cell 130 is the same as that of the second cell 120. However, the strut pattern of the third cell 130 has a phase difference from the second cell 120 along the circumferential direction C. Specifically, the phase difference corresponds to the angle between the first bridge 311 and the second bridge 322.

The bridges 310 to 360 may have the first bridge 311, the second bridge 322, and the third bridge 323 described above.

The first bridge 311 is the center of the strut pattern of the second cell 120.

The second bridge 322 is the center of the strut pattern of the third cell 130. The second bridge 322 is also connected to the fifth and sixth struts 223b and 224 of the first bridge 311 of the second cell 120.

The third bridge 323 is connected to the fifth and sixth struts 228b and 229 on the other side of the first bridge 311 of the second cell 120.

The first bridge 311, the second bridge 322, and the third bridge 323 may all be parallel to each other. Further, they may be arranged to be inclined with respect to the longitudinal direction L. [

The operation of the stent 100 according to such a configuration can be described with reference to the second cell 120.

First, when the stent 100 is inflated, the struts 221a, 221b, 222, 223a, 223b of the first bridge 311 are relatively compressed and the struts 226a of the other side of the first bridge 311 , 226b, 227, 228a, 228b are relatively inflated. At this time, since the first interval is larger than the second interval, the struts can be uniformly expanded.

Further, since the bridges 310 to 360 are inclined in the longitudinal direction L, the flexibility of the stent 100 is improved. Further, by the connection of these bridges 310-360, adjacent ones of the cells 110-170 have a phase difference in the strut pattern. Due to this phase difference, the possibility that struts of adjacent cells interfere with each other at the time of stent 100 deformation is lowered.

In addition, since the bridges 310 to 360 all have the same size and orientation, the forces received by the struts 210 to 270 have the advantage that they are the same in all struts, whether tensile or compressive.

In the specific design of the stent 100, the struts 210 to 270 were determined to have a length of 1.449 mm and a width of 0.1415 mm. This is confirmed by the finite element analysis and the experiment to have the optimum radial strength and flexibility.

Further, three bridges 310 to 360 are staggered in the circumferential direction C so as to have maximum flexibility while expanding the blood vessel with sufficient mechanical strength without causing injury after deploying the blood vessel with many bends Respectively. The more the number of bridges 310 to 360 is, the more the uniform expansion can be achieved. However, since more than three bridges lower the flexibility of the stent 100, three bridges are suitable.

In addition, the size of the cells 110 to 170 can be adjusted by adjusting the number and angles of the struts 210 to 270. At this time, 30 struts 210 to 270 are designed in the circumferential direction (C).

The evaluation of the appearance of the strut thus manufactured can be referred to the photographic image of Fig.

Referring to FIG. 3, it can be seen that after stenting, the stent is sufficiently spaced apart from struts of adjacent cells and does not overlap with each other.

Further, even when the stent is bent, it can be seen that there is no problem that the adjacent cells overlap each other.

The stent is not limited to the configuration and operation of the embodiments described above. The embodiments may be configured so that all or some of the embodiments may be selectively combined so that various modifications may be made.

100: stent 110 to 170: cell
210 to 270: Stent 310 to 360: Bridge

Claims

A plurality of struts arranged in a zigzag arrangement along the circumferential direction to form one cell; And a bridge connecting the one cell and another cell adjacent to the one cell,
The plurality of struts in each of the one cell and the other cell,
A first strut pair having an adjacent pair of struts having a first spacing; And
And a second strut pair having an adjacent pair of struts having a second spacing different from the first spacing.

The method according to claim 1,
The first strut pair and the second strut pair each comprise a first strut pair,
And one of the bridges, which is one of the bridges.

3. The method of claim 2,
The first strut pair comprises:
A first strut and a second strut on one side of the first bridge, and a fourth strut and a fifth strut on one side of the first bridge,
The second strut pair comprises:
A first strut and a second strut on the other side of the first bridge, and a fourth strut and a fifth strut on the other side of the first bridge.

The method of claim 3,
The bridge includes:
A second bridge connected to a portion where a fifth strut and a sixth strut meet at one side of the first bridge; And
Further comprising a third bridge connected to a portion of the fifth strut on the other side of the first bridge where the sixth strut meets.

5. The method of claim 4,
The first bridge
The first bridge, the second bridge, and the third bridge.

The method according to claim 1,
The bridge includes:
Wherein the one cell and the other cell are disposed obliquely with respect to the direction in which they are arranged one after the other.

The method according to claim 1,
Wherein the one cell and the other cell comprise:
Wherein the plurality of struts are the same in arrangement but have a phase difference along the circumferential direction.

5. The method of claim 4,
Wherein the phase difference between the one cell and the other cell,
And an angle along the circumferential direction between the first bridge and the second bridge.