IN2015DN01301A - - Google Patents

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Publication number
IN2015DN01301A
IN2015DN01301A IN1301DEN2015A IN2015DN01301A IN 2015DN01301 A IN2015DN01301 A IN 2015DN01301A IN 1301DEN2015 A IN1301DEN2015 A IN 1301DEN2015A IN 2015DN01301 A IN2015DN01301 A IN 2015DN01301A
Authority
IN
India
Application number
Inventor
Ulf Grawunder
Original Assignee
Nbe Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nbe Therapeutics Llc filed Critical Nbe Therapeutics Llc
Publication of IN2015DN01301A publication Critical patent/IN2015DN01301A/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1055Protein x Protein interaction, e.g. two hybrid selection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1082Preparation or screening gene libraries by chromosomal integration of polynucleotide sequences, HR-, site-specific-recombination, transposons, viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241Nucleotidyltransferases (2.7.7)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IN1301DEN2015 2012-07-18 2015-02-17 IN2015DN01301A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261673144P 2012-07-18 2012-07-18
EP12178529.9A EP2692865B1 (en) 2012-07-30 2012-07-30 Transposition-mediated identification of specific binding or functional proteins
PCT/EP2013/065214 WO2014013026A1 (en) 2012-07-18 2013-07-18 Transposition-mediated identification of specific binding or functional proteins

Publications (1)

Publication Number Publication Date
IN2015DN01301A true IN2015DN01301A (en) 2015-07-03

Family

ID=49775745

Family Applications (1)

Application Number Title Priority Date Filing Date
IN1301DEN2015 IN2015DN01301A (en) 2012-07-18 2015-02-17

Country Status (19)

Country Link
US (2) US10174309B2 (en)
EP (2) EP2692865B1 (en)
JP (1) JP6043431B2 (en)
CN (1) CN104640985B (en)
AU (1) AU2013291971B2 (en)
BR (1) BR112015000836B1 (en)
CA (1) CA2878982C (en)
DK (1) DK2692865T3 (en)
ES (1) ES2528892T3 (en)
HK (1) HK1209779A1 (en)
IL (1) IL236771A (en)
IN (1) IN2015DN01301A (en)
MX (1) MX338911B (en)
NZ (1) NZ705074A (en)
PT (1) PT2692865E (en)
SG (1) SG11201500280XA (en)
SI (1) SI2692865T1 (en)
WO (1) WO2014013026A1 (en)
ZA (1) ZA201500203B (en)

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SG11201806120WA (en) 2016-01-20 2018-08-30 Scripps Research Inst Ror1 antibody compositions and related methods
JP2019509023A (en) 2016-01-20 2019-04-04 ザ・スクリップス・リサーチ・インスティテュート ROR2 antibody composition and related methods
CA3017678A1 (en) 2016-04-04 2017-10-12 Eth Zurich Mammalian cell line for protein production and library generation
MX2019006573A (en) 2016-12-09 2019-11-18 Gliknik Inc Manufacturing optimization of gl-2045, a multimerizing stradomer.
BR112019009495A2 (en) 2016-12-09 2019-08-06 Gliknik Inc methods of treating inflammatory disorders with multivalent fc compounds
KR102523318B1 (en) 2016-12-16 2023-04-18 비-모젠 바이오테크놀로지스, 인크. Enhanced HAT family transposon-mediated gene delivery and associated compositions, systems, and methods
US11278570B2 (en) 2016-12-16 2022-03-22 B-Mogen Biotechnologies, Inc. Enhanced hAT family transposon-mediated gene transfer and associated compositions, systems, and methods
US11447546B2 (en) 2017-07-20 2022-09-20 Nbe-Therapeutics Ag Human antibodies binding to ROR2
CN111133002B (en) 2017-08-07 2024-05-24 恩比伊治疗股份公司 Anthracycline-based antibody drug conjugates with high in vivo tolerability
JP7407425B2 (en) * 2018-05-18 2024-01-04 ソルボンヌ・ユニヴェルシテ Molecular tools and methods for transgene integration and their transposition-dependent expression
EP3810764A2 (en) 2018-06-21 2021-04-28 B-Mogen Biotechnologies, Inc. Enhanced hat family transposon-mediated gene transfer and associated compositions, systems, and methods
EP3870604B1 (en) * 2018-10-26 2022-11-23 F. Hoffmann-La Roche AG Multispecific antibody screening method using recombinase mediated cassette exchange
JP2020146014A (en) * 2019-03-15 2020-09-17 株式会社東芝 Vector for measuring transposase activity, kit for measuring transposase activity, method for measuring transposase activity and method for cell separation
GB2605276B (en) 2019-09-03 2024-08-07 Myeloid Therapeutics Inc Methods and compositions for genomic integration
CN111139264B (en) * 2020-01-20 2021-07-06 天津达济科技有限公司 Method for constructing single-domain antibody library in mammalian cell line based on linear double-stranded DNA molecules
CN111471714A (en) * 2020-05-07 2020-07-31 西南大学 Eukaryotic transgenic cell line mediated by Minos transposon system and construction method
KR20230137340A (en) 2020-12-30 2023-10-04 알로노스 테라퓨틱스 인코포레이티드 Recombinant vector containing polycistronic expression cassette and method of using same
JP2024507929A (en) 2021-02-25 2024-02-21 アラウノス セラピューティクス インコーポレイテッド Recombinant vectors containing polycistronic expression cassettes and methods for their use
MX2023011638A (en) * 2021-03-31 2023-10-13 Ddbio Co Ltd Shang Hai Vector and method for screening functional antigen-binding protein.
WO2023150562A1 (en) 2022-02-01 2023-08-10 Alaunos Therapeutics, Inc. Methods for activation and expansion of t cells
WO2024102954A1 (en) 2022-11-10 2024-05-16 Massachusetts Institute Of Technology Activation induced clipping system (aics)

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Also Published As

Publication number Publication date
SG11201500280XA (en) 2015-02-27
BR112015000836B1 (en) 2021-12-21
CN104640985A (en) 2015-05-20
CA2878982C (en) 2017-01-03
US20190153433A1 (en) 2019-05-23
WO2014013026A1 (en) 2014-01-23
DK2692865T3 (en) 2015-02-16
WO2014013026A8 (en) 2014-12-04
CA2878982A1 (en) 2014-01-23
NZ705074A (en) 2017-04-28
EP2687599A1 (en) 2014-01-22
AU2013291971A1 (en) 2015-02-05
CN104640985B (en) 2021-05-11
AU2013291971B2 (en) 2016-02-04
SI2692865T1 (en) 2015-03-31
MX2015000885A (en) 2015-07-14
JP6043431B2 (en) 2016-12-14
MX338911B (en) 2016-05-05
HK1209779A1 (en) 2016-04-08
EP2692865B1 (en) 2014-12-10
JP2015522286A (en) 2015-08-06
US10174309B2 (en) 2019-01-08
US20150152406A1 (en) 2015-06-04
PT2692865E (en) 2015-02-06
IL236771A (en) 2016-09-29
BR112015000836A2 (en) 2017-12-12
ZA201500203B (en) 2015-12-23
EP2692865A1 (en) 2014-02-05
ES2528892T3 (en) 2015-02-13

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