US5827533A
(en)
*
|
1997-02-06 |
1998-10-27 |
Duke University |
Liposomes containing active agents aggregated with lipid surfactants
|
JP4467789B2
(en)
|
1997-09-18 |
2010-05-26 |
パシラ ファーマシューティカルズ インコーポレーテッド |
Sustained release liposome anesthetic composition
|
WO1999025319A1
(en)
*
|
1997-11-14 |
1999-05-27 |
Depotech Corporation |
Production of multivesicular liposomes
|
EP1633770B1
(en)
|
2003-06-13 |
2015-04-29 |
Alnylam Europe AG |
Double-stranded ribonucleic acid with increased effectiveness in an organism
|
AU2004305563C1
(en)
|
2003-12-11 |
2011-07-07 |
Sunovion Pharmaceuticals Inc. |
Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
|
CN1921893B
(en)
|
2004-02-24 |
2011-11-09 |
综合医院公司 |
Catalytic radiofluorination
|
US7674778B2
(en)
|
2004-04-30 |
2010-03-09 |
Alnylam Pharmaceuticals |
Oligonucleotides comprising a conjugate group linked through a C5-modified pyrimidine
|
BRPI0511070A
(en)
|
2004-06-17 |
2007-11-27 |
Infinity Pharmaceuticals Inc |
compounds and processes for inhibiting the interaction of bcl proteins with binding partners
|
WO2006124726A2
(en)
|
2005-05-12 |
2006-11-23 |
The General Hospital Corporation |
Novel biotinylated compositions
|
CA2659747C
(en)
|
2006-08-03 |
2015-09-08 |
Trustees Of Tufts College |
Non-flushing niacin analogues, and methods of use thereof
|
EP2065058A1
(en)
|
2007-11-28 |
2009-06-03 |
Koninklijke Philips Electronics N.V. |
Non-spherical contrast agents for CEST MRI based on bulk magnetic susceptibility effect
|
EP2067485A1
(en)
|
2007-12-07 |
2009-06-10 |
Koninklijke Philips Electronics N.V. |
Drug carrier providing MRI contrast enhancement
|
PL2331092T3
(en)
|
2008-08-21 |
2014-08-29 |
Univ Johns Hopkins |
Methods and compositions for administration of 3-halopyruvate and related compounds for the treatment of cancer
|
PT3133160T
(en)
|
2008-10-24 |
2019-03-18 |
Sarepta Therapeutics Inc |
Exon skipping compositions for dmd
|
EP2403863B1
(en)
|
2009-03-02 |
2013-08-28 |
Alnylam Pharmaceuticals Inc. |
Nucleic acid chemical modifications
|
EP2305216A1
(en)
|
2009-09-25 |
2011-04-06 |
Koninklijke Philips Electronics N.V. |
Two step ultrasound protocol for drug delivery
|
BR112012011381B8
(en)
|
2009-11-13 |
2021-05-25 |
Avi Biopharma Inc |
Isolated antiviral antisense oligonucleotide and pharmaceutical composition comprising the same
|
US9068185B2
(en)
|
2010-03-12 |
2015-06-30 |
Sarepta Therapeutics, Inc. |
Antisense modulation of nuclear hormone receptors
|
WO2011123621A2
(en)
|
2010-04-01 |
2011-10-06 |
Alnylam Pharmaceuticals Inc. |
2' and 5' modified monomers and oligonucleotides
|
WO2011133876A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising acyclic and abasic nucleosides and analogs
|
WO2011133868A2
(en)
|
2010-04-22 |
2011-10-27 |
Alnylam Pharmaceuticals, Inc. |
Conformationally restricted dinucleotide monomers and oligonucleotides
|
US9725479B2
(en)
|
2010-04-22 |
2017-08-08 |
Ionis Pharmaceuticals, Inc. |
5′-end derivatives
|
US9238042B2
(en)
|
2010-05-13 |
2016-01-19 |
Sarepta Therapeutics, Inc. |
Antisense modulation of interleukins 17 and 23 signaling
|
AU2011270719B2
(en)
|
2010-06-24 |
2015-09-24 |
Arisaph Pharmaceuticals, Inc. |
Niacin mimetics, and methods of use thereof
|
US8450316B2
(en)
|
2010-06-24 |
2013-05-28 |
Trustees Of Tufts College |
Niacin mimetics, and methods of use thereof
|
EP2407157A1
(en)
|
2010-07-13 |
2012-01-18 |
Koninklijke Philips Electronics N.V. |
Lipid bilayer carrier for drugs or imaging agents
|
CN103338747A
(en)
|
2011-01-28 |
2013-10-02 |
皇家飞利浦电子股份有限公司 |
Carriers for the local release of hydrophilic prodrugs
|
EP2535326A1
(en)
|
2011-06-16 |
2012-12-19 |
Koninklijke Philips Electronics N.V. |
Novel lipidomimetic compounds and uses thereof
|
MX2013015434A
(en)
|
2011-06-22 |
2014-10-14 |
Vyome Biosciences Pvt Ltd |
Conjugate-based antifungal and antibacterial prodrugs.
|
EP2732035A2
(en)
|
2011-07-15 |
2014-05-21 |
Sarepta Therapeutics, Inc. |
Methods and compositions for manipulating translation of protein isoforms from alternative initiation start sites
|
PT2788487T
(en)
|
2011-12-08 |
2018-07-03 |
Sarepta Therapeutics Inc |
Oligonucleotide analogues targeting human lmna
|
EP2794591A1
(en)
|
2011-12-23 |
2014-10-29 |
Novartis AG |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
CN104125953A
(en)
|
2011-12-23 |
2014-10-29 |
诺华股份有限公司 |
Compounds for inhibiting interaction of bcl2 with binding partners
|
AU2012355619A1
(en)
|
2011-12-23 |
2014-07-17 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
BR112014015442A8
(en)
|
2011-12-23 |
2017-07-04 |
Novartis Ag |
compounds and compositions for inhibiting bcl2 interaction with binding partners
|
MX2014007729A
(en)
|
2011-12-23 |
2015-01-12 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners.
|
EA201492007A1
(en)
|
2012-05-15 |
2015-03-31 |
Новартис Аг |
DERIVATIVES OF BENZAMIDE FOR INHIBITION OF ABL1, ABL2 AND BCR-ABL1 ACTIVITY
|
JP6080947B2
(en)
|
2012-05-15 |
2017-02-15 |
ノバルティス アーゲー |
Compounds and compositions for inhibiting the activity of ABL1, ABL2 and BCR-ABL1
|
WO2013171640A1
(en)
|
2012-05-15 |
2013-11-21 |
Novartis Ag |
Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1
|
NZ701626A
(en)
|
2012-05-15 |
2016-02-26 |
Novartis Ag |
Benzamide derivatives for inhibiting the activity of abl1, abl2 and bcr-abl1
|
US9789193B2
(en)
|
2012-06-15 |
2017-10-17 |
The Brigham And Women's Hospital, Inc. |
Compositions for treating cancer and methods for making the same
|
US9655977B2
(en)
|
2012-08-31 |
2017-05-23 |
The General Hospital Corporation |
Biotin complexes for treatment and diagnosis of alzheimer's disease
|
CN106414739A
(en)
|
2012-12-20 |
2017-02-15 |
萨雷普塔医疗公司 |
Improved exon skipping compositions for treating muscular dystrophy
|
LT2958907T
(en)
|
2013-02-19 |
2018-04-25 |
Novartis Ag |
Benzothiophene derivatives and compositions thereof as selective estrogen receptor degraders
|
RS58529B1
(en)
|
2013-03-14 |
2019-04-30 |
Sarepta Therapeutics Inc |
Exon skipping compositions for treating muscular dystrophy
|
EP2970963B1
(en)
|
2013-03-14 |
2019-10-23 |
Sarepta Therapeutics, Inc. |
Exon skipping compositions for treating muscular dystrophy
|
BR112015022998A2
(en)
|
2013-03-15 |
2017-11-14 |
Sarepta Therapeutics Inc |
improved compositions for treating muscular dystrophy
|
US10017531B2
(en)
|
2013-06-14 |
2018-07-10 |
Invictus Oncology Pvt. Ltd. |
Lipid-based platinum-N-heterocyclic carbene compounds and nanoparticles
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
WO2015092634A1
(en)
|
2013-12-16 |
2015-06-25 |
Novartis Ag |
1,2,3,4-tetrahydroisoquinoline compounds and compositions as selective estrogen receptor antagonists and degraders
|
JO3517B1
(en)
|
2014-01-17 |
2020-07-05 |
Novartis Ag |
N-azaspirocycloalkane substituted n-heteroaryl compounds and compositions for inhibiting the activity of shp2
|
EP3094629B1
(en)
|
2014-01-17 |
2018-08-22 |
Novartis AG |
1-(triazin-3-yl/pyridazin-3-yl)-piper(-azine)idine derivatives and compositions thereof for inhibiting the activity of shp2
|
ES2699351T3
(en)
|
2014-01-17 |
2019-02-08 |
Novartis Ag |
Derivatives of 1-pyridazin / triazin-3-yl-piper (-azine) / idine / pyrolidine and compositions thereof to inhibit the activity of SHP2
|
CN113559105A
(en)
|
2014-01-29 |
2021-10-29 |
维奥姆治疗有限公司 |
Treatment of resistant acne
|
UA120849C2
(en)
|
2014-03-12 |
2020-02-25 |
Ніппон Шин'Яку Ко., Лтд. |
Antisense nucleic acid
|
KR20160132496A
(en)
|
2014-04-03 |
2016-11-18 |
인빅터스 온콜로지 피비티. 엘티디. |
Supramolecular combinatorial therapeutics
|
CA2970795A1
(en)
|
2014-12-18 |
2016-06-23 |
Alnylam Pharmaceuticals, Inc. |
Reversir compounds
|
ES2918385T3
(en)
|
2015-05-19 |
2022-07-15 |
Akamara Therapeutics Inc |
Process for the preparation of supramolecular compounds based on platinum
|
WO2016196664A1
(en)
|
2015-06-01 |
2016-12-08 |
Cedars-Sinai Medical Center |
Methods and use of compounds that bind to rela of nf-kb
|
JP6878316B2
(en)
|
2015-06-19 |
2021-05-26 |
ノバルティス アーゲー |
Compounds and compositions for inhibiting the activity of SHP2
|
ES2741746T3
(en)
|
2015-06-19 |
2020-02-12 |
Novartis Ag |
Compounds and compositions to inhibit SHP2 activity
|
CN107922388B
(en)
|
2015-06-19 |
2020-12-29 |
诺华股份有限公司 |
Compounds and compositions for inhibiting SHP2 activity
|
TW201722965A
(en)
|
2015-08-16 |
2017-07-01 |
葛蘭素史密斯克藍智慧財產發展有限公司 |
Compounds for use in antibacterial applications
|
EP3355892A4
(en)
|
2015-09-30 |
2019-05-22 |
Sarepta Therapeutics, Inc. |
Methods for treating muscular dystrophy
|
WO2017064657A1
(en)
|
2015-10-16 |
2017-04-20 |
Invictus Oncology Pvt. Ltd. |
Fluorescent anticancer platinum drugs
|
EP3370712A4
(en)
|
2015-11-06 |
2019-10-09 |
The Johns Hopkins University |
Methods of treating liver fibrosis by administering 3-bromopyruvate
|
MA45616A
(en)
|
2016-04-29 |
2019-03-06 |
Sarepta Therapeutics Inc |
TARGET OLIGONUCLEOTIDE ANALOGUES LMNA HUMAN
|
ES2849560T3
(en)
|
2016-05-04 |
2021-08-19 |
Genoscience Pharma Sas |
Substituted 2,4-diamino-quinoline derivatives for use in the treatment of proliferative diseases
|
CA3023216A1
(en)
|
2016-06-14 |
2017-12-21 |
Novartis Ag |
Compounds and compositions for inhibiting the activity of shp2
|
EP3478697A1
(en)
|
2016-06-30 |
2019-05-08 |
Sarepta Therapeutics, Inc. |
Exon skipping oligomers for muscular dystrophy
|
ES2927079T3
(en)
|
2016-12-19 |
2022-11-02 |
Sarepta Therapeutics Inc |
Exon skipping oligomer conjugates for muscular dystrophy
|
AU2017382773A1
(en)
|
2016-12-19 |
2019-08-01 |
Sarepta Therapeutics, Inc. |
Exon skipping oligomer conjugates for muscular dystrophy
|
PT3554554T
(en)
|
2016-12-19 |
2022-11-08 |
Sarepta Therapeutics Inc |
Exon skipping oligomer conjugates for muscular dystrophy
|
AU2018256435A1
(en)
|
2017-04-20 |
2019-11-07 |
Atyr Pharma, Inc. |
Compositions and methods for treating lung inflammation
|
EA201991450A1
(en)
|
2017-09-22 |
2019-12-30 |
Сарепта Терапьютикс, Инк. |
OLIGOMER CONJUGATES FOR EXONISM SKIP IN MUSCULAR DYSTROPHY
|
EP3687547A1
(en)
|
2017-09-28 |
2020-08-05 |
Sarepta Therapeutics, Inc. |
Combination therapies for treating muscular dystrophy
|
EP3687577A1
(en)
|
2017-09-28 |
2020-08-05 |
Sarepta Therapeutics, Inc. |
Combination therapies for treating muscular dystrophy
|
EP3687519A1
(en)
|
2017-09-28 |
2020-08-05 |
Sarepta Therapeutics, Inc. |
Combination therapies for treating muscular dystrophy
|
US10765760B2
(en)
|
2018-05-29 |
2020-09-08 |
Sarepta Therapeutics, Inc. |
Exon skipping oligomer conjugates for muscular dystrophy
|
EP3806868A4
(en)
|
2018-06-13 |
2022-06-22 |
Sarepta Therapeutics, Inc. |
Exon skipping oligomers for muscular dystrophy
|
TW202020153A
(en)
|
2018-07-27 |
2020-06-01 |
美商薩羅塔治療公司 |
Exon skipping oligomers for muscular dystrophy
|
EP3620164A1
(en)
|
2018-09-05 |
2020-03-11 |
Genoscience Pharma SAS |
Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins b (ctsb), l (ctsl) and d (ctsd) related diseases
|
JP2022511055A
(en)
|
2018-12-13 |
2022-01-28 |
サレプタ セラピューティクス, インコーポレイテッド |
Exon skipping oligomer conjugate for muscular dystrophy
|
GB201821269D0
(en)
|
2018-12-28 |
2019-02-13 |
Nippon Shinyaku Co Ltd |
Myostatin signal inhibitor
|
WO2020168283A1
(en)
|
2019-02-14 |
2020-08-20 |
Akamara Therapeutics, Inc. |
Compounds and methods for managing cancer through immune system
|
SG11202108757XA
(en)
|
2019-03-28 |
2021-10-28 |
Sarepta Therapeutics Inc |
Methods for treating muscular dystrophy with casimersen
|
EP3955966A1
(en)
|
2019-04-18 |
2022-02-23 |
Sarepta Therapeutics, Inc. |
Compositions for treating muscular dystrophy
|
JP2022536495A
(en)
|
2019-06-19 |
2022-08-17 |
サレプタ セラピューティクス, インコーポレイテッド |
How to treat muscular dystrophy
|
IL294271A
(en)
|
2019-12-26 |
2022-08-01 |
Nippon Shinyaku Co Ltd |
Antisense nucleic acid that induces skipping of exon 50
|
CN115210376A
(en)
|
2020-02-28 |
2022-10-18 |
日本新药株式会社 |
Antisense nucleic acids inducing skipping of exon 51
|
US11357727B1
(en)
|
2021-01-22 |
2022-06-14 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
US11278494B1
(en)
|
2021-01-22 |
2022-03-22 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
US11033495B1
(en)
|
2021-01-22 |
2021-06-15 |
Pacira Pharmaceuticals, Inc. |
Manufacturing of bupivacaine multivesicular liposomes
|
AU2023235302A1
(en)
|
2022-03-17 |
2024-10-24 |
Sarepta Therapeutics, Inc. |
Phosphorodiamidate morpholino oligomer conjugates
|
WO2024073570A1
(en)
|
2022-09-28 |
2024-04-04 |
Altos Labs, Inc. |
Expression of regeneration factors in aged/senescent cells
|
WO2024155957A1
(en)
|
2023-01-19 |
2024-07-25 |
Altos Labs, Inc. |
Use of regeneration factors in organ transplantation
|
WO2024168010A2
(en)
|
2023-02-09 |
2024-08-15 |
Alnylam Pharmaceuticals, Inc. |
Reversir molecules and methods of use thereof
|