GR3004199T3 - - Google Patents
Info
- Publication number
- GR3004199T3 GR3004199T3 GR920400570T GR920400570T GR3004199T3 GR 3004199 T3 GR3004199 T3 GR 3004199T3 GR 920400570 T GR920400570 T GR 920400570T GR 920400570 T GR920400570 T GR 920400570T GR 3004199 T3 GR3004199 T3 GR 3004199T3
- Authority
- GR
- Greece
- Prior art keywords
- cyclosporins
- cyclodextrin
- fungal
- admixture
- rendered
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14070387 | 1987-06-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3004199T3 true GR3004199T3 (el) | 1993-03-31 |
Family
ID=15274767
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR920400570T GR3004199T3 (el) | 1987-06-04 | 1992-03-31 |
Country Status (10)
Country | Link |
---|---|
US (1) | US5051402A (el) |
EP (1) | EP0294239B1 (el) |
JP (1) | JP2577049B2 (el) |
AT (1) | ATE72629T1 (el) |
AU (1) | AU607506B2 (el) |
CA (1) | CA1325973C (el) |
DE (1) | DE3868438D1 (el) |
ES (1) | ES2033429T3 (el) |
GR (1) | GR3004199T3 (el) |
HK (1) | HK28097A (el) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5997856A (en) * | 1988-10-05 | 1999-12-07 | Chiron Corporation | Method and compositions for solubilization and stabilization of polypeptides, especially proteins |
JPH07111785B2 (ja) | 1990-01-19 | 1995-11-29 | 富士通株式会社 | 光ディスク |
US5227372A (en) * | 1990-03-07 | 1993-07-13 | Children's Medical Center Corporation | Method for retaining ophthalmological agents in ocular tissues |
HU208491B (en) * | 1990-11-27 | 1993-11-29 | Gyogyszerkutato Intezet | Process for producing oral pharmaceutical composition containing cyclosporin |
FR2670629B1 (fr) * | 1990-12-17 | 1995-03-10 | Moving Magnet Tech | Actionneur electromagnetique monophase rotatif. |
JP3099365B2 (ja) * | 1991-01-25 | 2000-10-16 | 藤沢薬品工業株式会社 | シクロスポリンaおよび/またはcの製造法 |
ES2098739T3 (es) * | 1992-05-13 | 1997-05-01 | Sandoz Ltd | Composiciones oftalmicas conteniendo una cyclosporin. |
US5494901A (en) * | 1993-01-05 | 1996-02-27 | Javitt; Jonathan C. | Topical compositions for the eye comprising a β-cyclodextrin derivative and a therapeutic agent |
NZ247516A (en) * | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
US5474979A (en) * | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
KR0167613B1 (ko) * | 1994-12-28 | 1999-01-15 | 한스 루돌프 하우스, 니콜 케르커 | 사이클로스포린-함유 연질캅셀제 조성물 |
JP3934705B2 (ja) * | 1995-05-26 | 2007-06-20 | ノバルティス ファーマ株式会社 | サイクロデキストリン組成物 |
JP2007056045A (ja) * | 1995-05-26 | 2007-03-08 | Nobaruteisu Fuaama Kk | サイクロデキストリン組成物 |
US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
US5766629A (en) | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
US5858401A (en) * | 1996-01-22 | 1999-01-12 | Sidmak Laboratories, Inc. | Pharmaceutical composition for cyclosporines |
US5968895A (en) * | 1996-12-11 | 1999-10-19 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US20070185032A1 (en) * | 1996-12-11 | 2007-08-09 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
DE29824679U1 (de) * | 1997-01-30 | 2002-03-28 | Novartis Ag, Basel | Pharmazeutische Zusammensetzungen |
NZ328751A (en) | 1997-09-16 | 1999-01-28 | Bernard Charles Sherman | Solid medicament containing an anionic surfactant and cyclosporin |
US20030220234A1 (en) * | 1998-11-02 | 2003-11-27 | Selvaraj Naicker | Deuterated cyclosporine analogs and their use as immunodulating agents |
DE69840586D1 (de) | 1997-10-08 | 2009-04-02 | Isotechnika Inc | Deuterierte Cyclosporin-analoga und ihre Verwendung als immunmodulierende Agenzien |
TW581681B (en) * | 1998-02-20 | 2004-04-01 | Nektar Therapeutics | Liquid crystal forms of cyclosporin |
WO2000012137A1 (en) | 1998-09-02 | 2000-03-09 | Allergan Sales, Inc. | Preserved cyclodextrin-containing compositions |
US20040152664A1 (en) * | 1998-09-02 | 2004-08-05 | Allergan, Inc. | Prednisolone compositions |
US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
WO2003033526A2 (en) * | 2001-10-19 | 2003-04-24 | Isotechnika Inc. | Synthesis of cyclosporin analogs |
JP2005506990A (ja) * | 2001-10-19 | 2005-03-10 | アイソテクニカ インコーポレーテッド | 新規のシクロスポリン類似体のマイクロエマルションプレコンセントレート |
US7354574B2 (en) | 2002-11-07 | 2008-04-08 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US20050112087A1 (en) * | 2003-04-29 | 2005-05-26 | Musso Gary F. | Pharmaceutical formulations for sustained drug delivery |
US7083802B2 (en) | 2003-07-31 | 2006-08-01 | Advanced Ocular Systems Limited | Treatment of ocular disease |
US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
US7087237B2 (en) | 2003-09-19 | 2006-08-08 | Advanced Ocular Systems Limited | Ocular solutions |
TW200517114A (en) | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
CA2546347A1 (en) | 2003-11-21 | 2005-06-09 | Combinatorx, Incorporated | Methods and reagents for the treatment of inflammatory disorders |
US7691812B2 (en) * | 2004-11-04 | 2010-04-06 | Trustees Of The University Of Pennsylvania | Methods for inhibiting growth of prolactin-responsive cancer cells with cyclosporine A or other cyclophilin inhibitors |
US7202209B2 (en) | 2005-07-13 | 2007-04-10 | Allergan, Inc. | Cyclosporin compositions |
US7297679B2 (en) * | 2005-07-13 | 2007-11-20 | Allergan, Inc. | Cyclosporin compositions |
US7276476B2 (en) * | 2005-07-13 | 2007-10-02 | Allergan, Inc. | Cyclosporin compositions |
US20070015693A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
US20070015691A1 (en) * | 2005-07-13 | 2007-01-18 | Allergan, Inc. | Cyclosporin compositions |
US7288520B2 (en) * | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
CA2615990A1 (en) | 2005-07-18 | 2007-01-25 | Minu, L.L.C. | Enhanced ocular neuroprotection/neurostimulation |
US7501393B2 (en) | 2005-07-27 | 2009-03-10 | Allergan, Inc. | Pharmaceutical compositions comprising cyclosporins |
US9839667B2 (en) | 2005-10-14 | 2017-12-12 | Allergan, Inc. | Prevention and treatment of ocular side effects with a cyclosporin |
US7745400B2 (en) * | 2005-10-14 | 2010-06-29 | Gregg Feinerman | Prevention and treatment of ocular side effects with a cyclosporin |
EP2218442A1 (en) | 2005-11-09 | 2010-08-18 | CombinatoRx, Inc. | Methods, compositions, and kits for the treatment of ophthalmic disorders |
DE102006051512A1 (de) | 2005-12-06 | 2007-06-14 | Pari GmbH Spezialisten für effektive Inhalation | Pharmazeutische Medikamentenzusammensetzungen mit Cyclosporin |
FI118537B (fi) * | 2006-03-08 | 2007-12-14 | Kuopion Yliopisto | Menetelmä syklodekstriinin kompleksoitumisen lisäämiseksi |
AU2016203191B2 (en) * | 2006-07-25 | 2018-03-01 | Allergan, Inc. | Cyclosporin compositions |
US9561178B2 (en) * | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
US20080146497A1 (en) * | 2006-07-25 | 2008-06-19 | Graham Richard S | Cyclosporin Compositions |
CN101896160A (zh) * | 2006-10-17 | 2010-11-24 | 阿勒根公司 | 环胞菌素组合物 |
CN101918019B (zh) | 2007-10-08 | 2014-11-26 | 奥里尼亚制药有限公司 | 包含钙调神经磷酸酶抑制剂或mTOR抑制剂的眼科组合物 |
US20100016219A1 (en) * | 2008-07-19 | 2010-01-21 | Jerry Zhang | Ophthalmic compositions containing solubilized cyclosporin |
CA2764635C (en) | 2009-06-09 | 2018-05-22 | Lux Biosciences, Inc. | Topical drug delivery systems for ophthalmic use |
CA2840734A1 (en) * | 2011-06-29 | 2013-01-03 | Allergan, Inc. | Macrogol 15 hydroxystearate formulations |
RU2017146716A (ru) * | 2015-05-29 | 2019-07-02 | Окулис Эхф. | Способ образования наночастиц циклоспорина а/ циклодекстрина |
CN105997863B (zh) * | 2016-07-21 | 2018-09-04 | 河南省眼科研究所 | 环孢素a滴眼液及其制备方法 |
US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
EP3993807A1 (en) | 2019-07-01 | 2022-05-11 | Oculis SA | Method for stabilizing the ph of an aqueous composition comprising a drug |
CN112724200B (zh) * | 2019-10-28 | 2022-09-27 | 上海云泽生物科技有限公司 | 一种稳定环孢霉素a的稀释液及其应用 |
JP2023548966A (ja) | 2020-11-09 | 2023-11-21 | スカイ・セラピューティクス・カンパニー・リミテッド | 固相のシクロスポリンa及びこれを含む分散組成物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
DE2907460A1 (de) * | 1978-03-07 | 1979-09-13 | Sandoz Ag | Neue resorbierbare galenische kompositionen |
PH19156A (en) * | 1982-02-01 | 1986-01-15 | Sandoz Ltd | Dihydrocyclosporin d in the treatment of multiple sclerosis |
DE3372705D1 (en) * | 1982-04-30 | 1987-09-03 | Takeda Chemical Industries Ltd | Pharmaceutical composition and its use |
DE3346123A1 (de) * | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
DE3580717D1 (de) * | 1984-08-02 | 1991-01-10 | Sandoz Ag | Pharmazeutische anwendung von (nva)2-cyclosporine. |
-
1988
- 1988-06-02 JP JP63136250A patent/JP2577049B2/ja not_active Expired - Lifetime
- 1988-06-03 AU AU17386/88A patent/AU607506B2/en not_active Expired
- 1988-06-06 AT AT88305138T patent/ATE72629T1/de not_active IP Right Cessation
- 1988-06-06 ES ES198888305138T patent/ES2033429T3/es not_active Expired - Lifetime
- 1988-06-06 CA CA000568734A patent/CA1325973C/en not_active Expired - Lifetime
- 1988-06-06 EP EP88305138A patent/EP0294239B1/en not_active Expired - Lifetime
- 1988-06-06 DE DE8888305138T patent/DE3868438D1/de not_active Expired - Lifetime
-
1990
- 1990-09-21 US US07/587,580 patent/US5051402A/en not_active Expired - Lifetime
-
1992
- 1992-03-31 GR GR920400570T patent/GR3004199T3/el unknown
-
1997
- 1997-03-06 HK HK28097A patent/HK28097A/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE72629T1 (de) | 1992-03-15 |
AU607506B2 (en) | 1991-03-07 |
CA1325973C (en) | 1994-01-11 |
US5051402A (en) | 1991-09-24 |
EP0294239A1 (en) | 1988-12-07 |
HK28097A (en) | 1997-03-06 |
JP2577049B2 (ja) | 1997-01-29 |
ES2033429T3 (es) | 1993-03-16 |
DE3868438D1 (de) | 1992-03-26 |
AU1738688A (en) | 1988-12-22 |
EP0294239B1 (en) | 1992-02-19 |
JPS6485921A (en) | 1989-03-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
GR3004199T3 (el) | ||
AU610636B2 (en) | Stabilised human protein preparations | |
IT1232243B (it) | Composizioni farmaceutiche a base di ciclosporine | |
CA2076663A1 (en) | Recessed Patellar Prosthesis | |
MY102660A (en) | Therapeutic system for sparingly soluble active ingredients | |
MY101593A (en) | Sustained release preparation. | |
DE68917129D1 (de) | Wasserlösliche antineoplastische taxolderivate. | |
GB8922026D0 (en) | Novel anti-viral and cytotoxic agent | |
ES2065906T3 (es) | Produccion de proteinas en formas activas. | |
WO1991015512A3 (en) | Hiv envelope polypeptides | |
GB8622012D0 (en) | Solid iodophor composition | |
GR3004303T3 (el) | ||
JPS6485990A (en) | Antihypertestoeronemia agent | |
FR2572932B1 (fr) | Medicament insoluble administre localement dans l'oreille | |
JPS6461429A (en) | Remedy for cancer | |
TR26166A (tr) | SUDA CÖZüLEBILEN FTALOSIYANIN 'LI BOYAR MADDELER, BUNLARIN üRETILMESINE MAHSUS USUL VE KULLANILMA- LARI. | |
RU96114157A (ru) | Способ лечения острых отравлений | |
Seo | Recommendations for the Improvement of the Medical Licensing Examination | |
PT968717E (pt) | Preparacao sob a forma galenica simples visando limitar os efeitos ocorridos durante a menopausa, e posteriormente, e tratamento com esta preparacao | |
IT1238692B (it) | Composizioni farmaceutiche a base di calcitonina per la somministrazione sublinguale | |
IT8723080A0 (it) | Componente d'arredamento, in particolare del tipo poltrona o simile. | |
JPS6429320A (en) | Drug composition | |
IT8620504A0 (it) | Derivati dell'1,2,4-triazolo farmacologicamente attivi. | |
MX6414A (es) | Pirrolo[1,2-a] [4,1]benzoxazepinas y procedimientopara su preparacion. | |
ATE100814T1 (de) | 19-nor-progesteron-derivate, ihre herstellung und anwendung. |