US6645969B1
(en)
|
1991-05-10 |
2003-11-11 |
Aventis Pharmaceuticals Inc. |
Aryl and heteroaryl quinazoline compounds which inhibit CSF-1R receptor tyrosine kinase
|
TW321649B
(en)
*
|
1994-11-12 |
1997-12-01 |
Zeneca Ltd |
|
GB9424233D0
(en)
*
|
1994-11-30 |
1995-01-18 |
Zeneca Ltd |
Quinazoline derivatives
|
GB9508538D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
EP0824525B1
(en)
*
|
1995-04-27 |
2001-06-13 |
AstraZeneca AB |
Quinazoline derivatives
|
GB9508537D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
GB9508565D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quiazoline derivative
|
GB9508535D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivative
|
GB9624482D0
(en)
*
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
WO1998014431A1
(en)
*
|
1996-10-01 |
1998-04-09 |
Kyowa Hakko Kogyo Co., Ltd. |
Nitrogenous heterocyclic compounds
|
US5760041A
(en)
*
|
1996-02-05 |
1998-06-02 |
American Cyanamid Company |
4-aminoquinazoline EGFR Inhibitors
|
JP4471404B2
(en)
|
1996-02-13 |
2010-06-02 |
アストラゼネカ ユーケイ リミテッド |
Quinazoline derivatives as VEGF inhibitors
|
GB9603095D0
(en)
*
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
GB9603097D0
(en)
*
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline compounds
|
DE69709319T2
(en)
|
1996-03-05 |
2002-08-14 |
Astrazeneca Ab, Soedertaelje |
4-ANILINOQUINAZOLINE DERIVATIVES
|
AU725533B2
(en)
|
1996-04-12 |
2000-10-12 |
Warner-Lambert Company |
Irreversible inhibitors of tyrosine kinases
|
GB9607729D0
(en)
*
|
1996-04-13 |
1996-06-19 |
Zeneca Ltd |
Quinazoline derivatives
|
FR2750862B1
(en)
*
|
1996-07-12 |
1998-10-16 |
Dupin Jean Pierre |
USE OF FUSED DIAZOTA HETEROCYCLES WITH AN AROMATIC OR HETEROAROMATIC SYSTEM FOR THE TREATMENT OF THROMBO-EMBOLIC DISEASES
|
HRP970371A2
(en)
|
1996-07-13 |
1998-08-31 |
Kathryn Jane Smith |
Heterocyclic compounds
|
DK0912559T3
(en)
|
1996-07-13 |
2003-03-10 |
Glaxo Group Ltd |
Condensed heterocyclic compounds as protein tyrosine kinase inhibitors
|
US6004967A
(en)
*
|
1996-09-13 |
1999-12-21 |
Sugen, Inc. |
Psoriasis treatment with quinazoline compounds
|
WO1998010767A2
(en)
*
|
1996-09-13 |
1998-03-19 |
Sugen, Inc. |
Use of quinazoline derivatives for the manufacture of a medicament in the treatment of hyperproliferative skin disorders
|
US6809097B1
(en)
*
|
1996-09-25 |
2004-10-26 |
Zeneca Limited |
Quinoline derivatives inhibiting the effect of growth factors such as VEGF
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
US6225318B1
(en)
|
1996-10-17 |
2001-05-01 |
Pfizer Inc |
4-aminoquinazolone derivatives
|
EP0837063A1
(en)
*
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
UA73073C2
(en)
*
|
1997-04-03 |
2005-06-15 |
Уайт Холдінгз Корпорейшн |
Substituted 3-cyan chinolines
|
US6002008A
(en)
*
|
1997-04-03 |
1999-12-14 |
American Cyanamid Company |
Substituted 3-cyano quinolines
|
US5929080A
(en)
*
|
1997-05-06 |
1999-07-27 |
American Cyanamid Company |
Method of treating polycystic kidney disease
|
ZA986729B
(en)
*
|
1997-07-29 |
1999-02-02 |
Warner Lambert Co |
Irreversible inhibitors of tyrosine kinases
|
ZA986732B
(en)
*
|
1997-07-29 |
1999-02-02 |
Warner Lambert Co |
Irreversible inhibitiors of tyrosine kinases
|
US6251912B1
(en)
|
1997-08-01 |
2001-06-26 |
American Cyanamid Company |
Substituted quinazoline derivatives
|
TW436485B
(en)
*
|
1997-08-01 |
2001-05-28 |
American Cyanamid Co |
Substituted quinazoline derivatives
|
US6323209B1
(en)
|
1997-11-06 |
2001-11-27 |
American Cyanamid Company |
Method of treating or inhibiting colonic polyps
|
RS49779B
(en)
|
1998-01-12 |
2008-06-05 |
Glaxo Group Limited, |
Byciclic heteroaromatic compounds as protein tyrosine kinase inhibitors
|
GB9800575D0
(en)
*
|
1998-01-12 |
1998-03-11 |
Glaxo Group Ltd |
Heterocyclic compounds
|
ATE413386T1
(en)
|
1998-01-29 |
2008-11-15 |
Amgen Inc |
PPAR-GAMMA MODULATORS
|
WO1999051582A1
(en)
|
1998-03-31 |
1999-10-14 |
Kyowa Hakko Kogyo Co., Ltd. |
Nitrogenous heterocyclic compounds
|
US6706721B1
(en)
|
1998-04-29 |
2004-03-16 |
Osi Pharmaceuticals, Inc. |
N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
|
HUP0102793A3
(en)
|
1998-05-28 |
2002-07-29 |
Parker Hughes Inst St Paul |
Quinazolines for treating brain tumor and medicaments containing them
|
US6800649B1
(en)
|
1998-06-30 |
2004-10-05 |
Parker Hughes Institute |
Method for inhibiting c-jun expression using JAK-3 inhibitors
|
US7354894B2
(en)
|
1998-08-18 |
2008-04-08 |
The Regents Of The University Of California |
Preventing airway mucus production by administration of EGF-R antagonists
|
JP2002539072A
(en)
|
1998-08-18 |
2002-11-19 |
ザ・レジェンツ・オブ・ザ・ユニバーシティー・オブ・カリフォルニア |
Prevention of airway mucus production by administration of EGF-R antagonists
|
EP1510212A1
(en)
*
|
1998-08-21 |
2005-03-02 |
Parker Hughes Institute |
Use of 4-substituted-quinazoline derivatives for producing therapeutic agents
|
HUP0103386A3
(en)
*
|
1998-08-21 |
2002-07-29 |
Parker Hughes Inst St Paul |
Use of quinazoline derivatives for producing pharmaceutical compositions having jak 3-inhibitor effect
|
US6288082B1
(en)
|
1998-09-29 |
2001-09-11 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
AU2012209038B2
(en)
*
|
1998-09-29 |
2013-09-26 |
Wyeth Holdings Corporation |
Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors
|
SK287767B6
(en)
*
|
1998-09-29 |
2011-09-05 |
Wyeth Holdings Corporation |
Substituted 3-cyanoquinolines
|
US6297258B1
(en)
|
1998-09-29 |
2001-10-02 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
GB9824579D0
(en)
*
|
1998-11-10 |
1999-01-06 |
Novartis Ag |
Organic compounds
|
PL204856B1
(en)
*
|
1999-01-22 |
2010-02-26 |
Kirin Pharma Kk |
Quinoline derivatives and quinazoline derivatives
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
JP3270834B2
(en)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
Heteroaromatic bicyclic derivatives useful as anticancer agents
|
GB9904103D0
(en)
|
1999-02-24 |
1999-04-14 |
Zeneca Ltd |
Quinoline derivatives
|
US6258820B1
(en)
|
1999-03-19 |
2001-07-10 |
Parker Hughes Institute |
Synthesis and anti-tumor activity of 6,7-dialkoxy-4-phenylamino-quinazolines
|
GB9910579D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
GB9910580D0
(en)
|
1999-05-08 |
1999-07-07 |
Zeneca Ltd |
Chemical compounds
|
US7041691B1
(en)
|
1999-06-30 |
2006-05-09 |
Amgen Inc. |
Compounds for the modulation of PPARγ activity
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
WO2001004111A1
(en)
*
|
1999-07-09 |
2001-01-18 |
Glaxo Group Limited |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
US6432979B1
(en)
|
1999-08-12 |
2002-08-13 |
American Cyanamid Company |
Method of treating or inhibiting colonic polyps and colorectal cancer
|
CA2384291A1
(en)
|
1999-09-21 |
2001-03-29 |
Astrazeneca Ab |
Quinazoline derivatives and their use as pharmaceuticals
|
HUP0204413A3
(en)
*
|
1999-09-21 |
2003-07-28 |
Astrazeneca Ab |
Quinazoline compounds, their preparation, their use and pharmaceutical compositions containing them
|
UA72946C2
(en)
|
1999-11-05 |
2005-05-16 |
Астразенека Аб |
Quinasoline derivatives as inhibitors of vascular endothelial growth factor (vegf)
|
US7087613B2
(en)
|
1999-11-11 |
2006-08-08 |
Osi Pharmaceuticals, Inc. |
Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
|
UA74803C2
(en)
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
A stable polymorph of n-(3-ethynylphenyl)-6,7-bis(2-methoxyetoxy)-4-quinazolinamine hydrochloride, a method for producing thereof (variants) and pharmaceutical use
|
UA75055C2
(en)
*
|
1999-11-30 |
2006-03-15 |
Пфайзер Продактс Інк. |
Benzoimidazole derivatives being used as antiproliferative agent, pharmaceutical composition based thereon
|
US6638929B2
(en)
|
1999-12-29 |
2003-10-28 |
Wyeth |
Tricyclic protein kinase inhibitors
|
US6977259B2
(en)
|
2000-01-28 |
2005-12-20 |
Astrazeneca Ab |
Quinoline derivatives and their use as aurora 2 kinase inhibitors
|
US6593324B2
(en)
|
2000-03-01 |
2003-07-15 |
Orion Corporation |
Dervatives of quinoline as alpha-2 antagonists
|
FI20000480A0
(en)
*
|
2000-03-01 |
2000-03-01 |
Orion Yhtymae Oyj |
Quinoline and naphthalene derivatives as alpha-2 antagonists
|
US6608048B2
(en)
|
2000-03-28 |
2003-08-19 |
Wyeth Holdings |
Tricyclic protein kinase inhibitors
|
US6521618B2
(en)
|
2000-03-28 |
2003-02-18 |
Wyeth |
3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
|
GB0007657D0
(en)
|
2000-03-29 |
2000-05-17 |
Celltech Therapeutics Ltd |
Chemical compounds
|
AU2001246850A1
(en)
*
|
2000-04-06 |
2001-10-23 |
Kyowa Hakko Kogyo Co. Ltd. |
Diagnostics and remedies for rheumatoid arthritis
|
ATE334973T1
(en)
|
2000-04-07 |
2006-08-15 |
Astrazeneca Ab |
QUINAZOLINE COMPOUNDS
|
US6653332B2
(en)
|
2000-05-03 |
2003-11-25 |
Tularik Inc. |
Combination therapeutic compositions and method of use
|
DE10023484A1
(en)
*
|
2000-05-09 |
2001-11-22 |
Schering Ag |
New 2-((cycloalkyl- or heterocyclyl-alkyl)-amino)-benzamide derivatives, are VEGF receptor, KDR kinase and FLT kinase inhibitors useful e.g. for treating tumors, psoriasis, arthritis or renal or ophthalmological diseases
|
UA73993C2
(en)
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Quinazoline derivatives for the treatment of tumours and a pharmaceutical composition
|
CA2413134C
(en)
*
|
2000-06-30 |
2010-05-11 |
Glaxo Group Limited |
Quinazoline ditosylate salt compounds
|
EP1315715B1
(en)
|
2000-08-18 |
2008-07-23 |
Millennium Pharmaceuticals, Inc. |
Quinazoline derivatives as kinase inhibitors
|
CZ2003486A3
(en)
|
2000-08-21 |
2003-05-14 |
Astrazeneca Ab |
Quinazoline derivatives, process of their preparation and pharmaceutical preparation in which the derivatives are comprised
|
DE10042059A1
(en)
*
|
2000-08-26 |
2002-03-07 |
Boehringer Ingelheim Pharma |
Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
|
HU230302B1
(en)
|
2000-10-20 |
2015-12-28 |
Eisai R&D Management Co., Ltd. |
Nitrogenous aromatic ring compounds and pharmaceutical compositions containing them
|
DE60144284D1
(en)
|
2000-11-01 |
2011-05-05 |
Millennium Pharm Inc |
NITROGENIC HETEROCYCLIC COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
|
AU2002210714A1
(en)
|
2000-11-02 |
2002-06-11 |
Astrazeneca Ab |
Substituted quinolines as antitumor agents
|
AU2001295791A1
(en)
*
|
2000-11-02 |
2002-05-15 |
Astrazeneca Ab |
4-substituted quinolines as antitumor agents
|
GB0104422D0
(en)
*
|
2001-02-22 |
2001-04-11 |
Glaxo Group Ltd |
Quinoline derivative
|
GB0110797D0
(en)
*
|
2001-05-02 |
2001-06-27 |
Celltech R&D Ltd |
Chemical compounds
|
US20060004437A1
(en)
|
2001-08-29 |
2006-01-05 |
Swaminathan Jayaraman |
Structurally variable stents
|
JP4383870B2
(en)
*
|
2001-10-17 |
2009-12-16 |
協和発酵キリン株式会社 |
Quinoline derivatives and quinazoline derivatives that inhibit fibroblast growth factor receptor autophosphorylation and pharmaceutical compositions containing them
|
GB0126433D0
(en)
*
|
2001-11-03 |
2002-01-02 |
Astrazeneca Ab |
Compounds
|
EP1444210B1
(en)
*
|
2001-11-03 |
2009-02-18 |
AstraZeneca AB |
Qunazoline derivatives as antitumor agents
|
OA12735A
(en)
*
|
2001-12-12 |
2006-06-29 |
Pfizer Prod Inc |
Salts forms of E-2-methoxy-N-(3-(4-(3-methyl-pyridin-3-yloxy)-phenylamino)-quinazolin-6-YL)-allyl)-acetamide, its preparation ant its use against cancer.
|
ATE446093T1
(en)
|
2001-12-24 |
2009-11-15 |
Astrazeneca Ab |
SUBSTITUTED QUINAZOLINE DERIVATIVES AS AURORA KINASE INHIBITORS
|
TW200406390A
(en)
|
2002-01-17 |
2004-05-01 |
Neurogen Corp |
Substituted quinazolin-4-ylamine analogues
|
EP1481971B1
(en)
*
|
2002-02-06 |
2011-11-16 |
Ube Industries, Ltd. |
Process for producing 4-aminoquinazoline compound
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
US7504408B2
(en)
|
2002-07-09 |
2009-03-17 |
Astrazeneca Ab |
Quinzoline derivatives for use in the treatment of cancer
|
GB0215823D0
(en)
|
2002-07-09 |
2002-08-14 |
Astrazeneca Ab |
Quinazoline derivatives
|
WO2004006846A2
(en)
|
2002-07-15 |
2004-01-22 |
Exelixis, Inc. |
Receptor-type kinase modulators and methods of use
|
EP1542989B1
(en)
|
2002-07-31 |
2007-04-18 |
Critical Outcome Technologies, Inc. |
Protein tyrosine kinase inhibitors
|
US7615565B2
(en)
|
2002-07-31 |
2009-11-10 |
Bayer Schering Pharma Aktiengesellschaft |
VEGFR-2 and VEGFR-3 inhibitory anthranilamide pyridines
|
US7629347B2
(en)
|
2002-10-09 |
2009-12-08 |
Critical Outcome Technologies, Inc. |
Protein tyrosine kinase inhibitors
|
GB0225579D0
(en)
|
2002-11-02 |
2002-12-11 |
Astrazeneca Ab |
Chemical compounds
|
SI1562955T1
(en)
|
2002-11-04 |
2008-06-30 |
Astrazeneca Ab |
Quinazoline derivatives as src tyrosine kinase inhibitors
|
US7488823B2
(en)
|
2003-11-10 |
2009-02-10 |
Array Biopharma, Inc. |
Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
|
PT1625121E
(en)
|
2002-12-20 |
2010-03-11 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
ATE370958T1
(en)
|
2002-12-24 |
2007-09-15 |
Astrazeneca Ab |
PHOSPHONOOXY-QUINAZOLINE DERIVATIVES AND THEIR PHARMACEUTICAL USE
|
GB0309850D0
(en)
*
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
WO2004106308A1
(en)
*
|
2003-05-27 |
2004-12-09 |
Pfizer Products Inc. |
Quinazolines and pyrido [3,4-d] pyrimidines as receptor tyrosine kinase inhibitors
|
PA8603801A1
(en)
*
|
2003-05-27 |
2004-12-16 |
Janssen Pharmaceutica Nv |
DERIVATIVES OF QUINAZOLINE
|
WO2006074147A2
(en)
|
2005-01-03 |
2006-07-13 |
Myriad Genetics, Inc. |
Nitrogen containing bicyclic compounds and therapeutical use thereof
|
US8309562B2
(en)
|
2003-07-03 |
2012-11-13 |
Myrexis, Inc. |
Compounds and therapeutical use thereof
|
TW200510373A
(en)
|
2003-07-14 |
2005-03-16 |
Neurogen Corp |
Substituted quinolin-4-ylamine analogues
|
US7329664B2
(en)
|
2003-07-16 |
2008-02-12 |
Neurogen Corporation |
Substituted (7-pyridyl-4-phenylamino-quinazolin-2-yl)-methanol analogues
|
US7501427B2
(en)
|
2003-08-14 |
2009-03-10 |
Array Biopharma, Inc. |
Quinazoline analogs as receptor tyrosine kinase inhibitors
|
NZ545459A
(en)
|
2003-08-14 |
2009-12-24 |
Array Biopharma Inc |
Quinazoline analogs as receptor tyrosine kinase inhibitors
|
ATE395346T1
(en)
|
2003-09-16 |
2008-05-15 |
Astrazeneca Ab |
QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
SI2392564T1
(en)
|
2003-09-26 |
2014-02-28 |
Exelixis, Inc. |
c-Met modulators and methods of use
|
JP4795022B2
(en)
*
|
2003-09-30 |
2011-10-19 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
Novel antifungal agent containing a heterocyclic compound
|
US7223761B2
(en)
|
2003-10-03 |
2007-05-29 |
Amgen Inc. |
Salts and polymorphs of a potent antidiabetic compound
|
AU2004282179B2
(en)
|
2003-10-14 |
2011-05-19 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein kinase inhibitors
|
US20090099165A1
(en)
|
2003-10-14 |
2009-04-16 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Protein Kinase Inhibitors
|
CN100450998C
(en)
|
2003-11-11 |
2009-01-14 |
卫材R&D管理有限公司 |
Urea derivative and process for producing the same
|
US7750160B2
(en)
|
2003-11-13 |
2010-07-06 |
Ambit Biosciences Corporation |
Isoxazolyl urea derivatives as kinase modulators
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
MXPA06007017A
(en)
|
2003-12-18 |
2006-08-31 |
Janssen Pharmaceutica Nv |
Pyrido- and pyrimidopyrimidine derivatives as anti- proliferative agents.
|
NZ547009A
(en)
|
2003-12-23 |
2009-09-25 |
Pfizer |
Novel quinoline derivatives
|
ATE413389T1
(en)
|
2004-02-03 |
2008-11-15 |
Astrazeneca Ab |
QUINAZOLINE DERIVATIVES
|
TW200529846A
(en)
|
2004-02-20 |
2005-09-16 |
Wyeth Corp |
3-quinolinecarbonitrile protein kinase inhibitors
|
JP2007532658A
(en)
*
|
2004-04-16 |
2007-11-15 |
スミスクライン ビーチャム コーポレーション |
How to treat cancer
|
US20080311076A1
(en)
*
|
2004-04-28 |
2008-12-18 |
Arrow Therapeutics Limited |
Morpholinylanilinoquinazoline Derivatives For Use As Antiviral Agents
|
ES2374553T3
(en)
|
2004-05-06 |
2012-02-17 |
Warner-Lambert Company Llc |
4-PHENYLAMINE-QUINAZOLIN-6-IL-AMIDAS.
|
KR20070038500A
(en)
*
|
2004-06-04 |
2007-04-10 |
아스트라제네카 아베 |
Quinazoline derivatives as erbb receptor tyrosine kinases
|
EP1797881B1
(en)
|
2004-09-17 |
2009-04-15 |
Eisai R&D Management Co., Ltd. |
Medicinal composition with improved stability and reduced gelation properties
|
TW200621251A
(en)
|
2004-10-12 |
2006-07-01 |
Neurogen Corp |
Substituted biaryl quinolin-4-ylamine analogues
|
ATE540935T1
(en)
|
2004-10-12 |
2012-01-15 |
Astrazeneca Ab |
CHINAZOLINE DERIVATIVES
|
US7906533B2
(en)
|
2004-11-03 |
2011-03-15 |
Bayer Schering Pharma Ag |
Nicotinamide pyridinureas as vascular endothelial growth factor (VEGF) receptor kinase inhibitors
|
EP1657241A1
(en)
|
2004-11-03 |
2006-05-17 |
Schering Aktiengesellschaft |
Novel anthranilamide pyridinureas as VEGF receptor kinase inhibitors
|
EP1655295A1
(en)
|
2004-11-03 |
2006-05-10 |
Schering Aktiengesellschaft |
Anthranilamide pyridinureas as VEGF receptor kinase inhibitors
|
NI200700147A
(en)
|
2004-12-08 |
2019-05-10 |
Janssen Pharmaceutica Nv |
QUINAZOLINE DERIVATIVES KINE INHIBITORS TARGETING MULTIP
|
CN101124228B
(en)
|
2004-12-14 |
2011-06-15 |
阿斯利康(瑞典)有限公司 |
Pyrazolopyrimidine compounds as antitumor agents
|
US8258145B2
(en)
|
2005-01-03 |
2012-09-04 |
Myrexis, Inc. |
Method of treating brain cancer
|
BRPI0607432A2
(en)
|
2005-02-26 |
2009-09-01 |
Astrazeneca Ab |
quinazoline derivative or a pharmaceutically acceptable salt thereof, compound, pharmaceutical composition, use of a quinazoline derivative or a pharmaceutically acceptable salt thereof, and process for the preparation of a quinazoline derivative or a pharmaceutically acceptable salt thereof
|
DE602006016564D1
(en)
*
|
2005-03-03 |
2010-10-14 |
Santen Pharmaceutical Co Ltd |
NEW CYCLIC COMPOUND WITH CHINOLYL ALKYLTHIOGROUP
|
EP1864980A4
(en)
|
2005-03-30 |
2010-08-18 |
Eisai R&D Man Co Ltd |
Antifungal agent containing pyridine derivative
|
US7825244B2
(en)
|
2005-06-10 |
2010-11-02 |
Janssen Pharmaceutica Nv |
Intermediates useful in the synthesis of alkylquinoline and alkylquinazoline kinase modulators, and related methods of synthesis
|
US8071768B2
(en)
|
2005-06-10 |
2011-12-06 |
Janssen Pharmaceutica, N.V. |
Alkylquinoline and alkylquinazoline kinase modulators
|
ES2341489T3
(en)
|
2005-07-27 |
2010-06-21 |
F.Hoffmann-La Roche Ag |
DERIVATIVES OF 4-ARILOXI QUINOLINA AS MODULATORS OF 5-HT6.
|
EP2281901B1
(en)
|
2005-08-02 |
2013-11-27 |
Eisai R&D Management Co., Ltd. |
Anti-tumour pharmaceutical composition with angiogenesis inhibitors
|
DE602006018331D1
(en)
|
2005-09-20 |
2010-12-30 |
Astrazeneca Ab |
4- (1H-INDAZOL-5-YLAMINO) CHINAZOLINE COMPOUNDS AS INHIBITORS OF ERBB RECEPTORT ROSINKINASE FOR THE TREATMENT OF CANCER
|
GB0520475D0
(en)
*
|
2005-10-07 |
2005-11-16 |
Arrow Therapeutics Ltd |
Chemical compounds
|
TWI385169B
(en)
|
2005-10-31 |
2013-02-11 |
Eisai R&D Man Co Ltd |
Heterocyclic substituted pyridine derivatives and antifungal agent containing same
|
DK1971601T3
(en)
|
2005-11-15 |
2010-02-08 |
Array Biopharma Inc |
N4-phenylquinazoline-4-amine derivatives and related compounds as ERBB Type 1 receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
|
US7960545B2
(en)
|
2005-11-23 |
2011-06-14 |
Natco Pharma Limited |
Process for the prepartion of erlotinib
|
DE602006015861D1
(en)
|
2005-12-21 |
2010-09-09 |
Abbott Lab |
ANTIVIRAL CONNECTIONS
|
WO2007081517A2
(en)
|
2005-12-21 |
2007-07-19 |
Abbott Laboratories |
Anti-viral compounds
|
JP2009521479A
(en)
|
2005-12-21 |
2009-06-04 |
アボット・ラボラトリーズ |
Antiviral compounds
|
CN101003514A
(en)
|
2006-01-20 |
2007-07-25 |
上海艾力斯医药科技有限公司 |
Derivative of quinazoline, preparation method and usage
|
UY30183A1
(en)
|
2006-03-02 |
2007-10-31 |
Astrazeneca Ab |
QUINOLINE DERIVATIVES
|
US8173806B2
(en)
|
2006-03-17 |
2012-05-08 |
Mitsubishi Gas Chemical Company, Inc. |
Method for production of quinazolin-4-one derivative
|
MEP43308A
(en)
|
2006-05-09 |
2011-02-10 |
Pfizer Prod Inc |
Cycloalkylamino acid derivatives and pharmaceutical compositions thereof
|
JP5190361B2
(en)
|
2006-05-18 |
2013-04-24 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
Antitumor agent for thyroid cancer
|
US8492377B2
(en)
|
2006-07-13 |
2013-07-23 |
Janssen Pharmaceutica Nv |
MTKI quinazoline derivatives
|
WO2008026748A1
(en)
|
2006-08-28 |
2008-03-06 |
Eisai R & D Management Co., Ltd. |
Antitumor agent for undifferentiated gastric cancer
|
WO2008035726A1
(en)
|
2006-09-21 |
2008-03-27 |
Eisai R & D Management Co., Ltd. |
Pyridine derivative substituted by heteroaryl ring, and antifungal agent comprising the same
|
EP1921070A1
(en)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclic heterocycles, medicaments comprising them, their use and process for their preparation
|
MX2009005252A
(en)
|
2006-11-17 |
2009-05-28 |
Abbott Lab |
Aminopyrrolidines as chemokine receptor antagonists.
|
CA2672737A1
(en)
|
2006-12-20 |
2008-11-06 |
Abbott Laboratories |
Anti-viral compounds
|
US8138191B2
(en)
|
2007-01-11 |
2012-03-20 |
Critical Outcome Technologies Inc. |
Inhibitor compounds and cancer treatment methods
|
KR101445892B1
(en)
|
2007-01-29 |
2014-09-29 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
Composition for treatment of undifferentiated-type of gastric cancer
|
KR20090116782A
(en)
|
2007-02-06 |
2009-11-11 |
베링거 인겔하임 인터내셔날 게엠베하 |
Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
|
CN101245050A
(en)
*
|
2007-02-14 |
2008-08-20 |
上海艾力斯医药科技有限公司 |
4-aniline quinazoline derivative salt
|
MX2009011090A
(en)
|
2007-04-18 |
2009-11-02 |
Pfizer Prod Inc |
Sulfonyl amide derivatives for the treatment of abnormal cell growth.
|
CN102702185A
(en)
|
2007-04-27 |
2012-10-03 |
卫材R&D管理有限公司 |
Heterocycle-substituted pyridine derivative's salt or crystal thereof
|
JP5460589B2
(en)
*
|
2007-07-13 |
2014-04-02 |
アイカジェン, インコーポレイテッド |
Sodium channel inhibitor
|
EP2185562B1
(en)
|
2007-07-27 |
2015-12-02 |
Janssen Pharmaceutica, N.V. |
Pyrrolopyrimidines useful for the treatment of proliferative diseases
|
CA2703767A1
(en)
|
2007-10-29 |
2009-05-07 |
Natco Pharma Limited |
Novel 4-(tetrazol-5-yl)-quinazoline derivatives as anti cancer agents
|
WO2009058937A2
(en)
*
|
2007-11-01 |
2009-05-07 |
Wyeth |
Heteroaryl ethers and processes for their preparation
|
JP5638244B2
(en)
|
2007-11-09 |
2014-12-10 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
Combination of angiogenesis inhibitors and antitumor platinum complexes
|
WO2009079797A1
(en)
|
2007-12-26 |
2009-07-02 |
Critical Outcome Technologies, Inc. |
Compounds and method for treatment of cancer
|
US8513287B2
(en)
|
2007-12-27 |
2013-08-20 |
Eisai R&D Management Co., Ltd. |
Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
|
PL2245026T3
(en)
|
2008-02-07 |
2013-01-31 |
Boehringer Ingelheim Int |
Spirocyclic heterocycles, medicaments containing said compounds, use thereof and method for their production
|
JP5746015B2
(en)
*
|
2008-04-16 |
2015-07-08 |
マックス プランク ゲゼルシャフト ツゥアー フェデルゥン デル ヴィッセンシャフテン エー フォー |
Quinoline derivatives as AXL kinase inhibitors
|
US8252805B2
(en)
|
2008-05-07 |
2012-08-28 |
Teva Pharmaceutical Industries Ltd. |
Forms of lapatinib ditosylate and processes for preparation thereof
|
BRPI0912170A2
(en)
|
2008-05-13 |
2015-10-13 |
Astrazeneca Ab |
compound, form, process for preparation thereof, pharmaceutical composition, use of a compound, and method for treating cancer in a warm-blooded animal
|
US8426430B2
(en)
|
2008-06-30 |
2013-04-23 |
Hutchison Medipharma Enterprises Limited |
Quinazoline derivatives
|
JP2010018531A
(en)
*
|
2008-07-09 |
2010-01-28 |
Sumitomo Seika Chem Co Ltd |
Method for producing 3-benzyloxybenzenethiol
|
CA2733153C
(en)
|
2008-08-08 |
2016-11-08 |
Boehringer Ingelheim International Gmbh |
Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
|
EP2241565A1
(en)
|
2009-01-15 |
2010-10-20 |
Universität Leipzig |
Aurora kinase inhibitors compounds
|
NZ594594A
(en)
|
2009-01-16 |
2013-11-29 |
Exelixis Inc |
Malate salt of n-(4-{ [6,7-bis(methyloxy)quinolin-4-yl]oxy} phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide, and crystalline forms thereof for the treatment of cancer
|
KR101106050B1
(en)
|
2009-03-25 |
2012-01-18 |
한국과학기술연구원 |
Aminoquinoline derivatives, preparation method thereof and pharmaceutical composition comprising the same
|
UA108618C2
(en)
|
2009-08-07 |
2015-05-25 |
|
APPLICATION OF C-MET-MODULATORS IN COMBINATION WITH THEMOSOLOMID AND / OR RADIATION THERAPY FOR CANCER TREATMENT
|
CA2772194A1
(en)
|
2009-09-01 |
2011-03-10 |
Pfizer Inc. |
Benzimidazole derivatives
|
PT3575288T
(en)
|
2009-09-03 |
2021-12-09 |
Bristol Myers Squibb Co |
Quinazolines as potassium ion channel inhibitors
|
US9180127B2
(en)
*
|
2009-12-29 |
2015-11-10 |
Dana-Farber Cancer Institute, Inc. |
Type II Raf kinase inhibitors
|
US8987272B2
(en)
|
2010-04-01 |
2015-03-24 |
Critical Outcome Technologies Inc. |
Compounds and method for treatment of HIV
|
ES2552977T3
(en)
*
|
2010-05-07 |
2015-12-03 |
Glaxosmithkline Intellectual Property Development Limited |
Amino-quinolines as kinase inhibitors
|
MX2012014776A
(en)
|
2010-06-25 |
2013-01-29 |
Eisai R&D Man Co Ltd |
Antitumor agent using compounds having kinase inhibitory effect in combination.
|
WO2012052948A1
(en)
|
2010-10-20 |
2012-04-26 |
Pfizer Inc. |
Pyridine- 2- derivatives as smoothened receptor modulators
|
AU2012225735B2
(en)
|
2011-03-04 |
2016-03-10 |
Glaxosmithkline Intellectual Property Development Limited |
Amino-quinolines as kinase inhibitors
|
RU2580609C2
(en)
|
2011-04-18 |
2016-04-10 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Anticancer therapeutic agent
|
ES2841809T3
(en)
|
2011-06-03 |
2021-07-09 |
Eisai R&D Man Co Ltd |
Biomarkers to predict and evaluate the degree of response of subjects with thyroid and kidney cancer to lenvatinib compounds
|
CN102850280B
(en)
*
|
2011-06-30 |
2015-06-10 |
陕西师范大学 |
6,7-dialkyloxy-4-substituted phenylamino quinazoline compounds and preparation methods
|
WO2013013614A1
(en)
*
|
2011-07-28 |
2013-01-31 |
南京英派药业有限公司 |
4-(3-heteroarylarylamino)quinazoline and 1-(3-heteroarylarylamino)isoquinoline as hedgehog pathway inhibitor and use thereof
|
TWI547494B
(en)
*
|
2011-08-18 |
2016-09-01 |
葛蘭素史克智慧財產發展有限公司 |
Amino quinazolines as kinase inhibitors
|
KR20140059246A
(en)
|
2011-09-22 |
2014-05-15 |
화이자 인코포레이티드 |
Pyrrolopyrimidine and purine derivatives
|
AR092529A1
(en)
|
2012-09-13 |
2015-04-22 |
Glaxosmithkline Llc |
AMINOQUINAZOLINE COMPOUND, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND USE OF THIS COMPOSITE FOR THE PREPARATION OF A MEDICINAL PRODUCT
|
AR092530A1
(en)
|
2012-09-13 |
2015-04-22 |
Glaxosmithkline Llc |
AMINO-QUINOLINE COMPOSITE, PHARMACEUTICAL COMPOSITION THAT INCLUDES IT AND USE OF THIS COMPOUND FOR THE PREPARATION OF A MEDICINAL PRODUCT
|
CN104755463A
(en)
|
2012-12-21 |
2015-07-01 |
卫材R&D管理有限公司 |
Amorphous form of quinoline derivative, and method for producing same
|
KR20210007046A
(en)
*
|
2013-02-01 |
2021-01-19 |
웰스태트 테러퓨틱스 코포레이션 |
Amine compounds having anti-inflammatory, antifungal, antiparasitic, and anticancer activity
|
ES2654100T3
(en)
|
2013-02-21 |
2018-02-12 |
Glaxosmithkline Intellectual Property Development Limited |
Quinazolines as kinase inhibitors
|
SG11201509278XA
(en)
|
2013-05-14 |
2015-12-30 |
Eisai R&D Man Co Ltd |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
ES2784423T3
(en)
|
2013-09-16 |
2020-09-25 |
Astrazeneca Ab |
Therapeutic polymer nanoparticles and methods for their manufacture and use
|
UA115388C2
(en)
|
2013-11-21 |
2017-10-25 |
Пфайзер Інк. |
2,6-substituted purine derivatives and their use in the treatment of proliferative disorders
|
WO2015155624A1
(en)
|
2014-04-10 |
2015-10-15 |
Pfizer Inc. |
Dihydropyrrolopyrimidine derivatives
|
AP2016009530A0
(en)
|
2014-04-30 |
2016-10-31 |
Pfizer |
Cycloalkyl-linked diheterocycle derivatives
|
WO2016001789A1
(en)
|
2014-06-30 |
2016-01-07 |
Pfizer Inc. |
Pyrimidine derivatives as pi3k inhibitors for use in the treatment of cancer
|
TWI721954B
(en)
|
2014-08-28 |
2021-03-21 |
日商衛材R&D企管股份有限公司 |
High-purity quinoline derivative and production method thereof
|
RU2017128583A
(en)
|
2015-02-25 |
2019-03-25 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
METHOD FOR REDUCING THE BITTER OF A QUINOLINE DERIVATIVE
|
CA2978226A1
(en)
|
2015-03-04 |
2016-09-09 |
Merck Sharpe & Dohme Corp. |
Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer
|
EP3283466A4
(en)
*
|
2015-04-16 |
2018-09-12 |
Icahn School of Medicine at Mount Sinai |
Ksr antagonists
|
KR102705821B1
(en)
|
2015-06-16 |
2024-09-12 |
가부시키가이샤 프리즘 바이오랩 |
Anticancer drug
|
WO2017009751A1
(en)
|
2015-07-15 |
2017-01-19 |
Pfizer Inc. |
Pyrimidine derivatives
|
CN108473435A
(en)
|
2015-10-05 |
2018-08-31 |
纽约市哥伦比亚大学理事会 |
The treatment of the removing and protein sickness of the activator of autophagy tide and phospholipase D and the protein masses including TAU
|
CN105384699B
(en)
|
2015-10-23 |
2016-10-12 |
中国人民解放军南京军区南京总医院 |
A kind of novel quinazoline quinoline derivant LU1501 and its preparation method and application
|
CN105503747B
(en)
*
|
2015-12-03 |
2017-12-19 |
中国人民解放军南京军区南京总医院 |
A kind of quinazoline derivant LU1507 and its preparation method and application
|
CN105669567A
(en)
*
|
2015-12-28 |
2016-06-15 |
上海应用技术学院 |
Tyrosine kinase inhibitor, preparation method and application thereof
|
JP7128204B2
(en)
|
2017-04-27 |
2022-08-30 |
アストラゼネカ・アクチエボラーグ |
C5-anilinoquinazoline compounds and their use in treating cancer
|
CN110546147B
(en)
*
|
2017-04-27 |
2023-05-23 |
阿斯利康(瑞典)有限公司 |
Phenoxyquinazoline compounds and their use in the treatment of cancer
|
US20200290978A1
(en)
*
|
2017-09-26 |
2020-09-17 |
The Regents Of The University Of California |
Compositions and methods for treating cancer
|
CN108373452B
(en)
*
|
2018-02-09 |
2020-10-27 |
安庆奇创药业有限公司 |
Preparation method of lapatinib key intermediate
|
CN111303024B
(en)
*
|
2018-12-12 |
2023-03-28 |
安徽中科拓苒药物科学研究有限公司 |
Quinoline-structured pan-KIT kinase inhibitor and application thereof
|
CN112778217B
(en)
*
|
2019-11-08 |
2024-01-26 |
沈阳化工研究院有限公司 |
Quinazoline compound and application thereof
|
WO2022258057A1
(en)
*
|
2021-06-11 |
2022-12-15 |
Jingrui Biopharma Co., Ltd. |
Compounds as anticancer agents
|
CN114436975B
(en)
*
|
2022-01-26 |
2023-10-31 |
贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) |
2-trifluoromethyl-4-aminoquinazoline compound and application thereof
|