GB2236852B - DNA probe based assays and intermediates useful in the synthesis of cleavable nucleic acids for use in such assays - Google Patents

DNA probe based assays and intermediates useful in the synthesis of cleavable nucleic acids for use in such assays

Info

Publication number
GB2236852B
GB2236852B GB8921605A GB8921605A GB2236852B GB 2236852 B GB2236852 B GB 2236852B GB 8921605 A GB8921605 A GB 8921605A GB 8921605 A GB8921605 A GB 8921605A GB 2236852 B GB2236852 B GB 2236852B
Authority
GB
United Kingdom
Prior art keywords
assays
synthesis
nucleic acids
dna probe
intermediates useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB8921605A
Other versions
GB8921605D0 (en
GB2236852A (en
Inventor
Frank Carr
R Cosstick
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SCOTGEN Ltd
Original Assignee
SCOTGEN Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SCOTGEN Ltd filed Critical SCOTGEN Ltd
Priority to GB8921605A priority Critical patent/GB2236852B/en
Publication of GB8921605D0 publication Critical patent/GB8921605D0/en
Publication of GB2236852A publication Critical patent/GB2236852A/en
Application granted granted Critical
Publication of GB2236852B publication Critical patent/GB2236852B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GB8921605A 1989-09-25 1989-09-25 DNA probe based assays and intermediates useful in the synthesis of cleavable nucleic acids for use in such assays Expired - Fee Related GB2236852B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB8921605A GB2236852B (en) 1989-09-25 1989-09-25 DNA probe based assays and intermediates useful in the synthesis of cleavable nucleic acids for use in such assays

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8921605A GB2236852B (en) 1989-09-25 1989-09-25 DNA probe based assays and intermediates useful in the synthesis of cleavable nucleic acids for use in such assays

Publications (3)

Publication Number Publication Date
GB8921605D0 GB8921605D0 (en) 1989-11-08
GB2236852A GB2236852A (en) 1991-04-17
GB2236852B true GB2236852B (en) 1994-04-06

Family

ID=10663576

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8921605A Expired - Fee Related GB2236852B (en) 1989-09-25 1989-09-25 DNA probe based assays and intermediates useful in the synthesis of cleavable nucleic acids for use in such assays

Country Status (1)

Country Link
GB (1) GB2236852B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7960119B2 (en) 1999-05-20 2011-06-14 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
USRE43097E1 (en) 1994-10-13 2012-01-10 Illumina, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
US8329404B2 (en) 2005-02-01 2012-12-11 Applied Biosystems Llc Reagents, methods, and libraries for bead-based sequencing
US8361713B2 (en) 1997-05-23 2013-01-29 Illumina, Inc. System and apparatus for sequential processing of analytes

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU187991A (en) * 1990-12-11 1994-09-09 Hoechst Aktiengesellschaft 3- (2) -AMINO-ALI THIOL-MODIFIED, FLUORESCENT-DYED NUCLEOSIDES, NUCLEOTIDS AND OLIGONUCLEOTIDES, PROCESS FOR THEIR OBTAINING AND THEIR USE
DE10142643A1 (en) * 2001-08-31 2003-04-24 Clondiag Chip Tech Gmbh Detection of interactions on probe arrays
CN102180926A (en) * 2011-04-28 2011-09-14 东南大学 Monomers of 3'thio-hypoxanthine deoxyribonucleoside phosphoramidite and application thereof
CN118043333A (en) * 2021-09-29 2024-05-14 国立研究开发法人科学技术振兴机构 Method and apparatus for cutting nucleic acid strand, and method and apparatus for producing double-stranded DNA

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2019562A (en) * 1978-04-05 1979-10-31 Syva Co Ligand-receptor assay method
WO1986004684A1 (en) * 1985-02-06 1986-08-14 Labsystems Oy Method for the determination of antibodies or antigens
WO1986006493A1 (en) * 1985-04-29 1986-11-06 Labsystems Oy Method and device for carrying out immunological assays
EP0362042A1 (en) * 1988-09-26 1990-04-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for the analysis of a specific sequence of DNA or RNA, reagents and kits therefor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2019562A (en) * 1978-04-05 1979-10-31 Syva Co Ligand-receptor assay method
WO1986004684A1 (en) * 1985-02-06 1986-08-14 Labsystems Oy Method for the determination of antibodies or antigens
WO1986006493A1 (en) * 1985-04-29 1986-11-06 Labsystems Oy Method and device for carrying out immunological assays
EP0362042A1 (en) * 1988-09-26 1990-04-04 Institut National De La Sante Et De La Recherche Medicale (Inserm) Method for the analysis of a specific sequence of DNA or RNA, reagents and kits therefor

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43097E1 (en) 1994-10-13 2012-01-10 Illumina, Inc. Massively parallel signature sequencing by ligation of encoded adaptors
US8361713B2 (en) 1997-05-23 2013-01-29 Illumina, Inc. System and apparatus for sequential processing of analytes
US8728729B2 (en) 1997-05-23 2014-05-20 Illumina, Inc. Method for sequential sequencing nucleic acids
US9273354B2 (en) 1997-05-23 2016-03-01 Illumina, Inc. System and apparatus for sequential processing of analytes
US7960119B2 (en) 1999-05-20 2011-06-14 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
US8206917B2 (en) 1999-05-20 2012-06-26 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
US8563246B2 (en) 1999-05-20 2013-10-22 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
US9163283B2 (en) 1999-05-20 2015-10-20 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
US8329404B2 (en) 2005-02-01 2012-12-11 Applied Biosystems Llc Reagents, methods, and libraries for bead-based sequencing
US8431691B2 (en) 2005-02-01 2013-04-30 Applied Biosystems Llc Reagents, methods, and libraries for bead-based sequencing
US9217177B2 (en) 2005-02-01 2015-12-22 Applied Biosystems, Llc Methods for bead-based sequencing
US9493830B2 (en) 2005-02-01 2016-11-15 Applied Biosystems, Llc Reagents, methods, and libraries for bead-based sequencing

Also Published As

Publication number Publication date
GB8921605D0 (en) 1989-11-08
GB2236852A (en) 1991-04-17

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19960925