GB2203740B - Novel peptides, their preparation and use - Google Patents

Novel peptides, their preparation and use

Info

Publication number
GB2203740B
GB2203740B GB8809228A GB8809228A GB2203740B GB 2203740 B GB2203740 B GB 2203740B GB 8809228 A GB8809228 A GB 8809228A GB 8809228 A GB8809228 A GB 8809228A GB 2203740 B GB2203740 B GB 2203740B
Authority
GB
United Kingdom
Prior art keywords
preparation
novel peptides
peptides
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8809228A
Other versions
GB8809228D0 (en
GB2203740A (en
Inventor
Beat Weidmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB8809228D0 publication Critical patent/GB8809228D0/en
Publication of GB2203740A publication Critical patent/GB2203740A/en
Application granted granted Critical
Publication of GB2203740B publication Critical patent/GB2203740B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GB8809228A 1987-04-23 1988-04-19 Novel peptides, their preparation and use Expired - Lifetime GB2203740B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3713613 1987-04-23

Publications (3)

Publication Number Publication Date
GB8809228D0 GB8809228D0 (en) 1988-05-25
GB2203740A GB2203740A (en) 1988-10-26
GB2203740B true GB2203740B (en) 1991-04-17

Family

ID=6326146

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8809228A Expired - Lifetime GB2203740B (en) 1987-04-23 1988-04-19 Novel peptides, their preparation and use

Country Status (6)

Country Link
JP (1) JPS63295541A (en)
BE (1) BE1002213A5 (en)
CH (1) CH676003A5 (en)
FR (1) FR2614533A1 (en)
GB (1) GB2203740B (en)
IT (1) IT1219542B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90872A0 (en) * 1988-07-08 1990-02-09 Smithkline Beckman Corp Retroviral protease binding peptides
EP0357332A3 (en) * 1988-08-24 1991-07-31 Merck & Co. Inc. Renin inhibitors useful for the treatment of aids by inhibition of hiv protease
EP0374097A3 (en) * 1988-12-15 1991-06-12 Ciba-Geigy Ag Use of peptide isosteres as retroviral protease inhibitors
DE3912829A1 (en) * 1989-04-19 1990-10-25 Bayer Ag USE OF RENININHIBITIC PEPTIDES AS AGENTS AGAINST RETROVIRUS
US5212157A (en) * 1989-06-06 1993-05-18 Bio-Mega, Inc. Enzyme inhibitors
US5126326A (en) * 1989-06-06 1992-06-30 Bio-Mega, Inc. Enzyme inhibiting peptide derivatives
DE3941235A1 (en) * 1989-12-14 1991-06-20 Bayer Ag NEW PEPTIDES, THEIR PREPARATION AND THEIR USE IN MEDICINAL PRODUCTS
DE4001236A1 (en) * 1990-01-18 1991-07-25 Bayer Ag New oligopeptide(s) contg. 2-amino-2-methyl propionic acid residue - are antiviral agents for human or veterinary therapy including treatment of AIDS and ARC
US5071837A (en) * 1990-11-28 1991-12-10 Warner-Lambert Company Novel renin inhibiting peptides
KR100220876B1 (en) * 1991-01-02 1999-10-01 슈테펜엘.네스비트 Anti-viral compounds
ES2094344T3 (en) * 1991-01-02 1997-01-16 Merrell Pharma Inc ANTI-VIRAL COMPOUNDS.
DE4126485A1 (en) * 1991-08-10 1993-02-11 Bayer Ag TRIFLUOROMETHYL-CONTAINING PSEUDOPEPTIDE
KR100316864B1 (en) * 1993-07-08 2002-11-13 메렐 파마슈티칼스 인크. Difluorostarone homologue
KR100308839B1 (en) * 1993-09-09 2002-10-04 메렐 파마슈티칼스 인크. Difluoro startone antiviral analogs
US6114380A (en) * 1995-12-18 2000-09-05 Merrell Pharmaceuticals Inc. Difluoro statone analogs

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206090A2 (en) * 1985-06-17 1986-12-30 Merck & Co. Inc. Peptide renin inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0258289A4 (en) * 1986-01-16 1991-01-02 Joseph Dellaria Peptide analogs

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206090A2 (en) * 1985-06-17 1986-12-30 Merck & Co. Inc. Peptide renin inhibitors

Also Published As

Publication number Publication date
BE1002213A5 (en) 1990-10-16
IT1219542B (en) 1990-05-18
FR2614533A1 (en) 1988-11-04
JPS63295541A (en) 1988-12-01
GB8809228D0 (en) 1988-05-25
GB2203740A (en) 1988-10-26
CH676003A5 (en) 1990-11-30
IT8847871A0 (en) 1988-04-20

Similar Documents

Publication Publication Date Title
JPS6419053A (en) Novel peptide derivative, manufacture and use
IL93055A0 (en) Polyimidesiloxanes,their preparation and use
JPS6454032A (en) Polydisilacyclobutasilazane and its preparation and use
GB2203740B (en) Novel peptides, their preparation and use
ZA881621B (en) Cyclic peptides and their preparation
GB2183638B (en) Polyfluoroalkylisoxazolylamines, their preparation and use
IL85234A0 (en) 1-aminomethyl-3-aryl-4-cyanopyrroles,their preparation and their use as pesticides
IL92281A0 (en) Polyimidesiloxanes,their preparation and use
IL86796A0 (en) Peptide derivatives,their preparation and their use
IL87779A0 (en) 4-azasaccharines,4-aza-dihydro-and-tetrahydro-saccharines and their preparation
IL88393A0 (en) Imidiates,their preparation and their use as insecticides
ZA882852B (en) Pyrrolealdehydes,their preparation and their use
AU8129987A (en) Pyrrolo-benzimidazoles, their preparation and use
AU2738088A (en) Soluble recombinant fce-receptor, the preparation and the use thereof
ZA878917B (en) 1-aryloxy-3-amino-2-propanols,the preparation and use thereof
IL85993A0 (en) 1-aralkylpyrazoles,their preparation and their use as pesticides
ZA872140B (en) Microlide compounds,their preparation and their use
AU8268887A (en) Aminoethylisoxazolidines, their preparation and use
ZA889506B (en) Soluble recombinant fce-receptor,the preparation and the use thereof
ZA885484B (en) N-alkenoyl enamides,their preparation and the use thereof
ZA875294B (en) Novel tetrahydrobenzothiazole-quinolines,their preparation and use
ZA877186B (en) New aryloxy-aminoalkanes,the preparation and use thereof
IL85375A0 (en) Cyclic peptides,their preparation and their use
ZA871007B (en) Aminourethanes,preparation and use thereof
JPS6456650A (en) Vinylchloroformates, manufacture and use

Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee