FR2643262B1 - PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS - Google Patents

PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS

Info

Publication number
FR2643262B1
FR2643262B1 FR9002086A FR9002086A FR2643262B1 FR 2643262 B1 FR2643262 B1 FR 2643262B1 FR 9002086 A FR9002086 A FR 9002086A FR 9002086 A FR9002086 A FR 9002086A FR 2643262 B1 FR2643262 B1 FR 2643262B1
Authority
FR
France
Prior art keywords
cyclosporins
pharmaceutical compositions
compositions based
pharmaceutical
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9002086A
Other languages
French (fr)
Other versions
FR2643262A1 (en
Inventor
Ulrich Posanski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10651981&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR2643262(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2643262A1 publication Critical patent/FR2643262A1/en
Application granted granted Critical
Publication of FR2643262B1 publication Critical patent/FR2643262B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR9002086A 1989-02-20 1990-02-19 PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS Expired - Lifetime FR2643262B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898903804A GB8903804D0 (en) 1989-02-20 1989-02-20 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
FR2643262A1 FR2643262A1 (en) 1990-08-24
FR2643262B1 true FR2643262B1 (en) 1993-06-11

Family

ID=10651981

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9002086A Expired - Lifetime FR2643262B1 (en) 1989-02-20 1990-02-19 PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS

Country Status (9)

Country Link
JP (1) JPH0611703B2 (en)
BE (1) BE1005236A3 (en)
CH (1) CH680650A5 (en)
CY (1) CY1886A (en)
DE (1) DE4005190A1 (en)
FR (1) FR2643262B1 (en)
GB (2) GB8903804D0 (en)
HK (1) HK149595A (en)
IT (1) IT1240765B (en)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639724A (en) 1984-07-24 1997-06-17 Sandoz Ltd. Cyclosporin galenic forms
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
HU208491B (en) * 1990-11-27 1993-11-29 Gyogyszerkutato Intezet Process for producing oral pharmaceutical composition containing cyclosporin
IL102236A0 (en) * 1991-06-27 1993-01-14 Ltt Inst Co Ltd Topical preparations containing cyclosporin
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
GB9113872D0 (en) * 1991-06-27 1991-08-14 Sandoz Ag Improvements in or relating to organic compounds
AU688920B2 (en) * 1991-06-27 1998-03-19 Novartis Ag Transesterified corn oil products
ES2098739T3 (en) 1992-05-13 1997-05-01 Sandoz Ltd OPHTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN.
US5759566A (en) * 1992-07-28 1998-06-02 Poli Industria Chimica Spa Microemulsion pharmaceutical compositions for the delivery of pharmaceutically active agents
ES2168271T3 (en) * 1992-09-25 2002-06-16 Novartis Ag PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINS.
DE4412201A1 (en) * 1993-04-20 1994-11-10 Rentschler Arzneimittel New pharmaceutical preparations for oral administration containing cyclosporin
CA2161143A1 (en) † 1993-04-20 1994-10-27 Monika Fleck New pharmaceutical preparations comprising cyclosporin for oral administration
NZ247516A (en) * 1993-04-28 1995-02-24 Bernard Charles Sherman Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant
DE4322826A1 (en) * 1993-07-08 1995-01-12 Galenik Labor Freiburg Gmbh Pharmaceutical preparation
DE4340781C3 (en) * 1993-11-30 2000-01-27 Novartis Ag Liquid preparations containing cyclosporin and process for their preparation
EP0694308A4 (en) * 1994-02-17 1997-09-10 Shiseido Co Ltd Cyclosporin-containing emulsion composition
US5891846A (en) * 1994-02-17 1999-04-06 Shiseido Company, Ltd. Cyclosporin-containing emulsion composition
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
US5474979A (en) * 1994-05-17 1995-12-12 Allergan, Inc. Nonirritating emulsions for sensitive tissue
BR9509550A (en) 1994-11-03 1997-09-16 Dresden Arzneimittel Cyclosporine formulations for oral administration with simple composition and high bioavailability and process for their production
US5603951A (en) * 1994-11-09 1997-02-18 Hanmi Pharm. Ind. Co., Ltd. Cyclosporin-containing soft capsule compositions
KR0167613B1 (en) * 1994-12-28 1999-01-15 한스 루돌프 하우스, 니콜 케르커 Cyclosporin-containing soft capsule compositions
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
CZ288631B6 (en) * 1996-01-18 2001-08-15 Galena, A. S. Therapeutic preparations containing cyclosporin
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
ES2229473T3 (en) 1997-01-30 2005-04-16 Novartis Ag PHARMACEUTICAL COMPOSITIONS WITHOUT OIL CONTAINING CYCLOSPORINE A.
CA2284000C (en) * 1997-03-12 2012-01-03 Abbott Laboratories Hydrophilic binary systems for the administration of cyclosporine
WO1998040051A1 (en) * 1997-03-12 1998-09-17 Abbott Laboratories Lipophilic binary systems for the administration of lipophilic compounds
CN1112927C (en) 1997-07-29 2003-07-02 法玛西雅厄普约翰美国公司 Self-emulsifying formulation for lipophilic compounds
BR9810866B1 (en) * 1997-07-29 2010-07-13 pharmaceutical composition in a self-emulsifying formulation form for lipophilic compounds.
US6346511B1 (en) 1997-09-08 2002-02-12 Panacea Biotec Limited Pharmaceutical composition comprising cyclosporin
US6008191A (en) * 1997-09-08 1999-12-28 Panacea Biotec Limited Pharmaceutical compositions containing cyclosporin
US6187747B1 (en) 1997-09-08 2001-02-13 Panacea Biotech Limited Pharmaceutical composition comprising cyclosporin
US5981607A (en) * 1998-01-20 1999-11-09 Allergan Emulsion eye drop for alleviation of dry eye related symptoms in dry eye patients and/or contact lens wearers
ID25908A (en) * 1998-03-06 2000-11-09 Novartis Ag EMULSION PRACTONCENTRATES CONTAINING CYCLOSPORINE OR MACROLIDES
DE19859910C2 (en) * 1998-12-23 2001-03-22 Ratiopharm Gmbh Oral medicine
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
GB9912476D0 (en) 1999-05-28 1999-07-28 Novartis Ag Organic compounds
AU2127400A (en) * 1999-11-02 2001-05-14 Cipla Limited A pharmaceutical composition for the administration of water-insoluble pharmaceutically active substances and process for preparation thereof
GB2362573A (en) * 2000-05-25 2001-11-28 Cipla Ltd Cyclosporin formulation
DK1151755T3 (en) * 2000-05-04 2005-06-27 Panacea Biotec Ltd Pharmaceutical preparation containing cyclosporin as active ingredient
DE10030378A1 (en) * 2000-06-21 2002-03-14 Audit Inst For Medical Service New pharmaceutical composition for topical application of water-insoluble and / or poorly water-soluble active ingredients
US6979672B2 (en) 2002-12-20 2005-12-27 Polichem, S.A. Cyclosporin-based pharmaceutical compositions
JP4381037B2 (en) 2003-06-04 2009-12-09 花王株式会社 Oil composition
ES2573539T3 (en) 2005-03-21 2016-06-08 Teva Czech Industries S.R.O. Crystallization inhibitor and its use in gelatin capsules
RU2623206C2 (en) 2005-04-15 2017-06-22 Кларус Терапьютикс, Инк. Pharmaceutical delivery systems for hydrophobic medicinal products and compositions containing them
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
FR2914188B1 (en) * 2007-03-28 2012-06-22 Trophos NEW CHOLEST-4-EN-3-ONE OXIME COMPOSITION
GB2451811A (en) 2007-08-09 2009-02-18 Ems Sa Delivery composition for solubilising water-insoluble pharmaceutical active ingredients
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
CA2690490C (en) * 2010-01-19 2012-06-26 Accucaps Industries Limited Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
JP6448553B2 (en) * 2014-01-16 2019-01-09 マルホ株式会社 External preparation for transdermal administration
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
US20170246187A1 (en) 2014-08-28 2017-08-31 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
WO2018098501A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
CN113966223A (en) * 2019-04-11 2022-01-21 R·P·舍勒科技有限责任公司 Formulations for oral delivery of proteins, peptides and small molecules with poor permeability

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2907460A1 (en) * 1978-03-07 1979-09-13 Sandoz Ag NEW RESORBABLE GALENIC COMPOSITIONS
CH641356A5 (en) * 1979-02-27 1984-02-29 Sandoz Ag Pharmaceutical compositions containing cyclosporin
BE895724A (en) * 1982-02-01 1983-07-28 Sandoz Sa NEW THERAPEUTIC USE OF DIHYDROCYCLOSPORIN D

Also Published As

Publication number Publication date
CY1886A (en) 1996-04-05
IT9047650A1 (en) 1990-08-21
IT1240765B (en) 1993-12-17
JPH02255623A (en) 1990-10-16
GB8903804D0 (en) 1989-04-05
DE4005190A1 (en) 1990-08-23
BE1005236A3 (en) 1993-06-08
GB2228198A (en) 1990-08-22
FR2643262A1 (en) 1990-08-24
GB9003616D0 (en) 1990-04-11
HK149595A (en) 1995-09-29
CH680650A5 (en) 1992-10-15
IT9047650A0 (en) 1990-02-20
JPH0611703B2 (en) 1994-02-16
GB2228198B (en) 1992-12-16

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Legal Events

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