DE60231309D1 - Nanopartikelabbildungssystem und -verfahren - Google Patents
Nanopartikelabbildungssystem und -verfahrenInfo
- Publication number
- DE60231309D1 DE60231309D1 DE60231309T DE60231309T DE60231309D1 DE 60231309 D1 DE60231309 D1 DE 60231309D1 DE 60231309 T DE60231309 T DE 60231309T DE 60231309 T DE60231309 T DE 60231309T DE 60231309 D1 DE60231309 D1 DE 60231309D1
- Authority
- DE
- Germany
- Prior art keywords
- substrate
- module
- spots
- imaging
- automatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nanotechnology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Colloid Chemistry (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement Of Radiation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31010201P | 2001-08-03 | 2001-08-03 | |
US36673202P | 2002-03-22 | 2002-03-22 | |
PCT/US2002/024604 WO2003053535A2 (en) | 2001-08-03 | 2002-08-02 | Nanoparticle imaging system and method |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60231309D1 true DE60231309D1 (de) | 2009-04-09 |
Family
ID=26977210
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60231309T Expired - Lifetime DE60231309D1 (de) | 2001-08-03 | 2002-08-02 | Nanopartikelabbildungssystem und -verfahren |
Country Status (9)
Country | Link |
---|---|
US (4) | US7110585B2 (de) |
EP (1) | EP1412536B1 (de) |
JP (1) | JP4347053B2 (de) |
AT (1) | ATE423975T1 (de) |
AU (1) | AU2002365247B2 (de) |
CA (1) | CA2455118C (de) |
DE (1) | DE60231309D1 (de) |
NZ (1) | NZ531212A (de) |
WO (1) | WO2003053535A2 (de) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7098320B1 (en) | 1996-07-29 | 2006-08-29 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US6506564B1 (en) * | 1996-07-29 | 2003-01-14 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US6582921B2 (en) * | 1996-07-29 | 2003-06-24 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses thereof |
US7169556B2 (en) * | 1996-07-29 | 2007-01-30 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US6750016B2 (en) * | 1996-07-29 | 2004-06-15 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US6984491B2 (en) * | 1996-07-29 | 2006-01-10 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
US20050037397A1 (en) * | 2001-03-28 | 2005-02-17 | Nanosphere, Inc. | Bio-barcode based detection of target analytes |
US6974669B2 (en) * | 2000-03-28 | 2005-12-13 | Nanosphere, Inc. | Bio-barcodes based on oligonucleotide-modified nanoparticles |
US20030096321A1 (en) * | 1999-05-19 | 2003-05-22 | Jose Remacle | Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips |
AU774593C (en) * | 2000-01-13 | 2005-06-23 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
AU7687001A (en) * | 2000-07-11 | 2002-01-21 | Nanospherre Inc | Method of detection by enhancement of silver staining |
US20060040286A1 (en) * | 2001-03-28 | 2006-02-23 | Nanosphere, Inc. | Bio-barcode based detection of target analytes |
US20030113740A1 (en) * | 2001-04-26 | 2003-06-19 | Mirkin Chad A. | Oligonucleotide-modified ROMP polymers and co-polymers |
US7147687B2 (en) * | 2001-05-25 | 2006-12-12 | Nanosphere, Inc. | Non-alloying core shell nanoparticles |
WO2002096262A2 (en) * | 2001-05-25 | 2002-12-05 | Northwestern University | Non-alloying core shell nanoparticles |
DE60231309D1 (de) | 2001-08-03 | 2009-04-09 | Nanosphere Inc | Nanopartikelabbildungssystem und -verfahren |
US20040146917A1 (en) * | 2001-08-03 | 2004-07-29 | Nanosphere, Inc. | Nanoparticle imaging system and method |
CN100354430C (zh) | 2001-09-06 | 2007-12-12 | 基因描绘系统有限公司 | 一种检测样品中靶细胞或病毒的方法 |
EP1466015B1 (de) | 2001-11-09 | 2008-08-06 | Nanosphere, Inc. | Biokonjugat-nanopartikelsonden |
US7361310B1 (en) * | 2001-11-30 | 2008-04-22 | Northwestern University | Direct write nanolithographic deposition of nucleic acids from nanoscopic tips |
AU2002360446A1 (en) * | 2001-11-30 | 2003-06-17 | Northwestern University | Direct write nanolithographic deposition of nucleic acids from nanoscopic tips |
US20030211488A1 (en) | 2002-05-07 | 2003-11-13 | Northwestern University | Nanoparticle probs with Raman spectrocopic fingerprints for analyte detection |
US7227988B2 (en) * | 2002-07-01 | 2007-06-05 | Xerox Corporation | Prioritized PDL segmentation producing two bit selector |
CA2490413C (en) * | 2002-07-02 | 2011-08-30 | Nanosphere, Inc. | Nanoparticle polyanion conjugates and methods of use thereof in detecting analytes |
WO2005001143A2 (en) * | 2003-02-27 | 2005-01-06 | Nanosphere, Inc. | Label-free gene expression profiling with universal nanoparticle probes in microarray assay format |
US20050250094A1 (en) * | 2003-05-30 | 2005-11-10 | Nanosphere, Inc. | Method for detecting analytes based on evanescent illumination and scatter-based detection of nanoparticle probe complexes |
EP1704405A1 (de) | 2003-12-31 | 2006-09-27 | The President and Fellows of Harvard College | Testvorrichtung und verfahren |
US7555154B2 (en) * | 2004-03-10 | 2009-06-30 | Biomedical Photometrics Inc. | Fully automated segmentation of genetic micro-array images |
DE102004013052A1 (de) * | 2004-03-10 | 2005-09-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Charakterisierung von technischen Oberflächen |
WO2006028601A2 (en) * | 2004-07-26 | 2006-03-16 | Nanosphere, Inc. | Method for distinguishing methicillin resistant s. aureus from methicillin sensitive s. aureus in a mixed culture |
US7612769B2 (en) * | 2004-09-14 | 2009-11-03 | E.I. Du Pont De Nemours And Company | Computer-implemented methods for organizing image data produced by resonant Mie scattering of light from microparticles and resulting data structures |
US20070154903A1 (en) * | 2005-06-23 | 2007-07-05 | Nanosphere, Inc. | Selective isolation and concentration of nucleic acids from complex samples |
EP1748030B1 (de) * | 2005-07-07 | 2016-04-20 | Fei Company | Verfahren und Apparat zur statistischen Charakterisierung von Nano-Partikeln |
ATE489482T1 (de) * | 2005-08-19 | 2010-12-15 | Nanosphere Inc | Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon |
US20070105125A1 (en) * | 2005-11-08 | 2007-05-10 | Tsai George P | Chemical array housing having a gas delivery element and methods of using the same |
JP4991252B2 (ja) * | 2006-11-10 | 2012-08-01 | 株式会社日立ハイテクノロジーズ | 電気泳動装置、及び電気泳動分析方法 |
US8040959B2 (en) * | 2006-12-11 | 2011-10-18 | Texas Instruments Incorporated | Dynamic resource allocation to improve MIMO detection performance |
US8194920B2 (en) * | 2007-02-16 | 2012-06-05 | Ford Global Technologies, Llc | Method and system for detecting objects using far infrared images |
US7692785B2 (en) * | 2007-03-29 | 2010-04-06 | General Electric Company | System and method for optical power management |
US20090116696A1 (en) * | 2007-05-29 | 2009-05-07 | Mckernan Steffen | System, method and machine-readable medium for characterizing nanotube materials |
TWI384214B (zh) * | 2008-01-18 | 2013-02-01 | Nat Univ Chung Cheng | Biological sensing device and its system |
KR101435522B1 (ko) | 2008-01-23 | 2014-09-02 | 삼성전자 주식회사 | 바이오 칩 |
CN101978073B (zh) | 2008-01-25 | 2014-12-10 | 诊疗实验室 | 用于评估药物反应的方法和组合物 |
JP2009229103A (ja) * | 2008-03-19 | 2009-10-08 | Toshiba Corp | 金属コロイドの定量方法 |
EP2344679B1 (de) * | 2008-09-24 | 2018-05-23 | First Light Biosciences, Inc. | Kits und vorrichtungen zur erkennung von analyten |
GB2464747B (en) * | 2008-10-10 | 2013-05-15 | Hai Kang Life Corp Ltd | Method for detection of analyte in microarray of samples and apparatus for performing such method |
US8306780B2 (en) * | 2009-01-26 | 2012-11-06 | Exelis Inc. | Data quality and ancillary data checking for Raman sensor |
WO2010111656A2 (en) | 2009-03-27 | 2010-09-30 | Life Technologies Corporation | Systems and methods for assessing images |
JP5288634B2 (ja) | 2010-03-31 | 2013-09-11 | 富士フイルム株式会社 | 呈色測定装置および方法 |
ES2614181T3 (es) | 2010-08-14 | 2017-05-30 | University Of Massachusetts | Partícula de pared celular de levadura para suministro de nanopartículas direccionadas al receptor |
CN102297965A (zh) * | 2011-05-23 | 2011-12-28 | 无锡安迪生物工程有限公司 | 一种氯吡脲快速检测卡及其检测方法 |
JP5914992B2 (ja) * | 2011-06-02 | 2016-05-11 | ソニー株式会社 | 表示制御装置、表示制御方法、およびプログラム |
US20140072959A1 (en) | 2012-09-12 | 2014-03-13 | Force Diagnostics, Inc. | Rapid tests for insurance underwriting |
SG10201703538UA (en) | 2012-10-17 | 2017-06-29 | Bio Rad Laboratories Inc | Image capture for large analyte arrays |
EP2979092B1 (de) | 2013-03-29 | 2018-05-30 | Nima Labs, Inc. | Tragbare vorrichtung zum nachweis von schadstoffen |
US10466236B2 (en) | 2013-03-29 | 2019-11-05 | Nima Labs, Inc. | System and method for detecting target substances |
US10254279B2 (en) | 2013-03-29 | 2019-04-09 | Nima Labs, Inc. | System and method for detection of target substances |
US8736685B1 (en) * | 2013-12-11 | 2014-05-27 | Anritsu Company | Systems and methods for measuring brightness response of a camera operating in automatic exposure mode |
WO2017059103A1 (en) * | 2015-09-30 | 2017-04-06 | Nima Labs, Inc. | System and method for detecting target substances |
US9835842B2 (en) * | 2015-12-04 | 2017-12-05 | Omnivision Technologies, Inc. | Microscope attachment |
US10878562B2 (en) * | 2015-12-10 | 2020-12-29 | Qiagen GmgH | Method for determining the overall brightness of at least one object in a digital image |
CN105738294B (zh) * | 2016-03-01 | 2018-11-06 | 江苏大学 | 基于单目多视成像的穗状水果自动检测装置及方法 |
CN106442238B (zh) * | 2016-07-22 | 2023-06-23 | 华北电力大学 | 一种检测空气中颗粒浓度的装置 |
JP6317003B2 (ja) * | 2017-02-27 | 2018-04-25 | 株式会社Screenホールディングス | 撮像装置および撮像方法 |
CN107167478A (zh) * | 2017-04-25 | 2017-09-15 | 明基材料有限公司 | 片材面内标记检测方法及装置 |
CN109061797B (zh) * | 2017-06-13 | 2020-03-27 | 京东方科技集团股份有限公司 | 导光结构、显示装置及视角调节方法 |
WO2019204784A1 (en) | 2018-04-19 | 2019-10-24 | First Light Biosciences, Inc. | Detection of targets |
WO2020014296A1 (en) | 2018-07-12 | 2020-01-16 | Luminex Corporation | Systems and methods for performing variable sample preparation and analysis processes |
CN113227342A (zh) * | 2019-01-09 | 2021-08-06 | 株式会社日立高新技术 | 核酸分析用基板、核酸分析用流动池以及图像分析方法 |
CN110177280A (zh) * | 2019-04-02 | 2019-08-27 | 苏州摩比信通智能系统有限公司 | 二维解码器的曝光调节方法 |
US20220276235A1 (en) * | 2019-07-18 | 2022-09-01 | Essenlix Corporation | Imaging based homogeneous assay |
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US4202037A (en) * | 1977-04-22 | 1980-05-06 | Der Loos Hendrik Van | Computer microscope apparatus and method for superimposing an electronically-produced image from the computer memory upon the image in the microscope's field of view |
GB2196219A (en) * | 1986-10-11 | 1988-04-20 | Astromed Ltd | Imaging of light-opaque specimens by transmission of radiation therethrough |
JPH07104943B2 (ja) * | 1988-02-29 | 1995-11-13 | 株式会社日立製作所 | 物体認識装置 |
US5428690A (en) * | 1991-09-23 | 1995-06-27 | Becton Dickinson And Company | Method and apparatus for automated assay of biological specimens |
US5820879A (en) * | 1993-02-12 | 1998-10-13 | Access Pharmaceuticals, Inc. | Method of delivering a lipid-coated condensed-phase microparticle composition |
US5753261A (en) * | 1993-02-12 | 1998-05-19 | Access Pharmaceuticals, Inc. | Lipid-coated condensed-phase microparticle composition |
US5654006A (en) * | 1993-02-12 | 1997-08-05 | Mayo Foundation For Medical Education And Research | Condensed-phase microparticle composition and method |
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US6361944B1 (en) * | 1996-07-29 | 2002-03-26 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses therefor |
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WO1998037417A1 (en) * | 1997-02-20 | 1998-08-27 | The Regents Of The University Of California | Plasmon resonant particles, methods and apparatus |
JPH10241625A (ja) | 1997-02-24 | 1998-09-11 | Hitachi Ltd | プラズマイオン源質量分析装置及び方法 |
KR100540314B1 (ko) | 1997-03-31 | 2006-01-10 | 마이크로썸, 엘엘씨 | 광학 검사 모듈, 및 통합 처리 도구 내에서 기판 상의 입자 및 결함을 검출하기 위한 방법 |
US6294327B1 (en) * | 1997-09-08 | 2001-09-25 | Affymetrix, Inc. | Apparatus and method for detecting samples labeled with material having strong light scattering properties, using reflection mode light and diffuse scattering |
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JP2000241120A (ja) * | 1999-02-23 | 2000-09-08 | Fanuc Ltd | 計測装置 |
CA2371658C (en) * | 1999-05-19 | 2012-01-31 | Advanced Array Technologies S.A. | Method for the identification and/or the quantification of a target compound |
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JP2001168159A (ja) * | 1999-12-03 | 2001-06-22 | Sony Corp | 検査装置及び検査方法 |
AU2001233200A1 (en) * | 2000-01-31 | 2001-08-07 | Board Of Regents, The University Of Texas System | Portable sensor array system |
US20020107640A1 (en) * | 2000-11-14 | 2002-08-08 | Ideker Trey E. | Methods for determining the true signal of an analyte |
AU2002249994A1 (en) | 2001-04-19 | 2002-11-05 | Maven Technologies Llc. | Imaging apparatus and method |
DE60231309D1 (de) | 2001-08-03 | 2009-04-09 | Nanosphere Inc | Nanopartikelabbildungssystem und -verfahren |
US6707958B2 (en) | 2001-11-20 | 2004-03-16 | Agilent Technologies, Inc. | Biochemical assay device using frustrated total internal reflection modulator with an imaging optical waveguide |
WO2003060446A1 (en) | 2002-01-12 | 2003-07-24 | Maven Technologies, Llc | Apparatus and method for imaging |
US7163823B2 (en) | 2002-01-28 | 2007-01-16 | Nanosphere, Inc. | DNA hybridization device and method |
AU2003299508A1 (en) | 2002-05-14 | 2004-06-07 | Nanosphere, Inc. | Electrical detection of dna hybridization and specific binding events |
-
2002
- 2002-08-02 DE DE60231309T patent/DE60231309D1/de not_active Expired - Lifetime
- 2002-08-02 AU AU2002365247A patent/AU2002365247B2/en not_active Ceased
- 2002-08-02 AT AT02805501T patent/ATE423975T1/de not_active IP Right Cessation
- 2002-08-02 EP EP02805501A patent/EP1412536B1/de not_active Expired - Lifetime
- 2002-08-02 WO PCT/US2002/024604 patent/WO2003053535A2/en active IP Right Grant
- 2002-08-02 CA CA2455118A patent/CA2455118C/en not_active Expired - Lifetime
- 2002-08-02 US US10/210,959 patent/US7110585B2/en not_active Expired - Lifetime
- 2002-08-02 NZ NZ531212A patent/NZ531212A/en not_active IP Right Cessation
- 2002-08-02 JP JP2003554291A patent/JP4347053B2/ja not_active Expired - Lifetime
-
2006
- 2006-09-08 US US11/530,138 patent/US20070148665A1/en not_active Abandoned
- 2006-09-08 US US11/530,110 patent/US7773790B2/en active Active
-
2010
- 2010-08-09 US US12/853,047 patent/US20120063653A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2003053535B1 (en) | 2003-11-06 |
EP1412536B1 (de) | 2009-02-25 |
US7110585B2 (en) | 2006-09-19 |
AU2002365247B2 (en) | 2006-06-08 |
WO2003053535A3 (en) | 2003-09-12 |
US20120063653A1 (en) | 2012-03-15 |
EP1412536A2 (de) | 2004-04-28 |
NZ531212A (en) | 2006-01-27 |
JP4347053B2 (ja) | 2009-10-21 |
US20030068638A1 (en) | 2003-04-10 |
WO2003053535A9 (en) | 2003-12-24 |
JP2005521033A (ja) | 2005-07-14 |
US7773790B2 (en) | 2010-08-10 |
WO2003053535A2 (en) | 2003-07-03 |
EP1412536A4 (de) | 2005-12-28 |
ATE423975T1 (de) | 2009-03-15 |
US20070041624A1 (en) | 2007-02-22 |
CA2455118C (en) | 2012-01-17 |
US20070148665A1 (en) | 2007-06-28 |
CA2455118A1 (en) | 2003-07-03 |
AU2002365247A1 (en) | 2003-07-09 |
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