CN108040465A - Aggregating apparatus for single or multiple containers - Google Patents
Aggregating apparatus for single or multiple containers Download PDFInfo
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- CN108040465A CN108040465A CN201680035766.0A CN201680035766A CN108040465A CN 108040465 A CN108040465 A CN 108040465A CN 201680035766 A CN201680035766 A CN 201680035766A CN 108040465 A CN108040465 A CN 108040465A
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- aggregating apparatus
- fluid
- container
- pin
- aggregating
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- 230000004931 aggregating effect Effects 0.000 title claims description 318
- 239000012530 fluid Substances 0.000 claims abstract description 377
- 238000003780 insertion Methods 0.000 claims abstract description 25
- 230000037431 insertion Effects 0.000 claims abstract description 25
- 239000012080 ambient air Substances 0.000 claims abstract description 15
- 239000003570 air Substances 0.000 claims description 80
- 230000007246 mechanism Effects 0.000 claims description 40
- 238000007789 sealing Methods 0.000 claims description 32
- 230000002209 hydrophobic effect Effects 0.000 claims description 30
- 230000000295 complement effect Effects 0.000 claims description 22
- 238000004891 communication Methods 0.000 claims description 20
- 238000009423 ventilation Methods 0.000 claims description 11
- 239000011324 bead Substances 0.000 claims description 6
- 230000001737 promoting effect Effects 0.000 claims description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 2
- 238000002347 injection Methods 0.000 description 12
- 239000007924 injection Substances 0.000 description 12
- 238000005086 pumping Methods 0.000 description 12
- 238000001802 infusion Methods 0.000 description 9
- 238000010276 construction Methods 0.000 description 6
- 241000723353 Chrysanthemum Species 0.000 description 5
- 235000007516 Chrysanthemum Nutrition 0.000 description 5
- 108060003951 Immunoglobulin Proteins 0.000 description 5
- 239000007789 gas Substances 0.000 description 5
- 102000018358 immunoglobulin Human genes 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000000354 decomposition reaction Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 239000000645 desinfectant Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000001990 intravenous administration Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000036961 partial effect Effects 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- 238000004659 sterilization and disinfection Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 230000003213 activating effect Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
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- 230000002708 enhancing effect Effects 0.000 description 2
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- 239000007788 liquid Substances 0.000 description 2
- 230000000474 nursing effect Effects 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 230000000284 resting effect Effects 0.000 description 2
- 230000002441 reversible effect Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000003915 air pollution Methods 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229920001971 elastomer Polymers 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 239000011259 mixed solution Substances 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000000149 penetrating effect Effects 0.000 description 1
- 230000002572 peristaltic effect Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
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- 229920003002 synthetic resin Polymers 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2013—Piercing means having two piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
- A61J1/2058—Connecting means having multiple connecting ports
- A61J1/2062—Connecting means having multiple connecting ports with directional valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2079—Filtering means
- A61J1/2082—Filtering means for gas filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/1407—Infusion of two or more substances
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Pulmonology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Stackable Containers (AREA)
- External Artificial Organs (AREA)
- Supplying Of Containers To The Packaging Station (AREA)
- Sampling And Sample Adjustment (AREA)
- Nozzles (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Harvester Elements (AREA)
- Filling Of Jars Or Cans And Processes For Cleaning And Sealing Jars (AREA)
Abstract
A kind of device (10) for being used to collect the fluid for coming from the container unit (12) with least one container (14,16) is provided, and the device includes：Ingress port (18) with least one access road (22,24), the ingress port are configured for receiving fluid or ambient air；And the outlet port (26) with least one exit passageway (32,34), the outlet port are configured for transporting fluid into annex.Ingress port and outlet port (18,26) are all arranged in described device (10).Cavity (40) is arranged to be used for accommodating the insertion of container unit (12), to collect the fluid for coming from least one container (14,16).At least one pin (48,50) is arranged in the cavity, and is configured for piercing through the plug (44,46) of at least one container when container unit is transferred to lower position from upper position.
Description
Cross reference
This application claims enjoy in the U.S. Provisional Patent Application sequence number 62/182,099 submitted on June 19th, 2015 35
U.S.C. the priority under § 119 (e), the U.S. Provisional Patent Application are merged in by reference.
Technical field
The disclosure relates generally to the aggregating apparatus for the treatment of purpose, and relates more specifically to be configured for converging
Collect the inclusion from pharmaceutical containers for device used at the same time.
Background technology
In many cases, pharmaceutical preparation or fluid are since their chemically and physically stability is separation before use.
Therefore, fluid is individually packed and stored, mixed until by fluid with venoclysis to patient.Traditionally, by curing
Professional is treated by injecting first fluid in vial or container with second fluid to realize the mixing of fluid.
After mixing first fluid and second fluid, mixed solution is retracted in injection tube and is injected intravenously and arrives patient's body.At certain
In a little situations, before patient is conveyed to, two kinds of solution are mixed in larger container, or the solution of mixing is transferred to
Larger container, such as intravenous (IV) infusion bag of the larger container or external member.
Some medical fluids are transfused without mixing successively.For example, first fluid can be transfused first to improve second
Body is delivered to patient or the condition handled by patient.Described in commonly assigned U.S. Patent number 8,684,433 for defeated
Exemplary double containers for medical use units of the first and second fluid of note, the United States Patent (USP) are incorporated herein by reference.In some situations
In, it is necessary to the medical fluid of several bottles is combined to provide correct dosage for patient.With some immune deficiency illness
Patient treated by injecting relatively great amount of immunoglobulin (IG) fluid.Apply first fluid medicament to strengthen pair
Body as the opposite high viscosity IG fluids of second medicament receives.Routinely, the medical professional for being transfused fluid verifies stream
The characteristic and concentration of body, wipe the corresponding plug of each container using disinfectant (such as alcohol), by each container
Plug pierce through so as to trandfer fluid, using multiple injection tubes and collect bag and collect fluid, Ran Houyi from cell therefor respectively
It is secondary that fluid infusion is carried out to patient.In some cases, twin containers unit by hand hoisting or is suspended on IV pole, is made
Obtain one or more fluids and be transported to by gravity flowing and collect bag.
Due to the process (being in alternately by patient in some cases) of this multi-step, conventional infusion methods are held
Easily there is maloperation and mistake.For example, bottle, bottle or other containers may be misused, in some instances it may even be possible to damage or rupture.This
Outside, several manual steps are needed at present to realize required infusion order in gnotobasis, due to substantial amounts of manual step
The substantial amounts of time is wasted, and needs substantial amounts of space to carry out the stock of storage device during use.If medical fluid
Sterile infusion may be affected, then may cause bacterium or environmental pollution.These any problems all may be to by fluid infusion
Health to patient and patient has a negative impact.
Therefore, it is necessary to research and develop a kind of improved aggregating apparatus, it is in a manner of simpler and is more reliable to be single or multiple
Pharmaceutical containers provide improved infusion methods.
The content of the invention
The present invention relates to the aggregating apparatus for collecting the medical fluid from least one containers for medical use, it is by above-mentioned hand
Many steps integration in dynamic step.The importance of the aggregating apparatus of the present invention, which has been to provide, to be configured for receiving
The center cavity of containers for medical use, to collect medical fluid from containers for medical use, and without loading different containers for medical use repeatedly.
The inner lumen pin of the plug for piercing through each containers for medical use is provided with the cavity, and is provided with locking mechanism, is used
Containers for medical use to be reliably held in the cavity of the aggregating apparatus of the present invention.
In certain embodiments, two or more aggregating apparatus of the invention can be linked or connected with complementary relationship,
So that individually containers for medical use is sequentially transfused to user or patient automatically, without replacing medical appearance during operation
Device.Only as an example, the outlet of the aggregating apparatus of the present invention is linked to or chrysanthemum is linked to the entrance of another aggregating apparatus,
To promote the uninterrupted connection of the fluid path between the aggregating apparatus of all-links.In such configuration, can be not
Interrupt or do not manipulate and be transfused two kinds to user with relatively high volume (in 100 milliliters of scope) in the case of containers for medical use
Or more kind medical fluid.Contemplating the aggregating apparatus of link can reverse from above-mentioned orientation.
In one embodiment, there is provided a kind of remittance for being used to collect fluid from the container unit with least one container
Acquisition means, and the aggregating apparatus is including the ingress port with least one access road and with least one exit passageway
Outlet port, which, which is configured for receiving fluid or ambient air, the outlet port, is configured to use
In transporting fluid into annex.Ingress port and outlet port are all set on such devices.It is provided with for accommodating container
The cavity of the insertion of unit, to collect fluid from least one container.At least one pin is arranged in the cavity,
And at least one pin is configured for when container unit is transferred to lower position from upper position described in puncture
The plug of at least one container.
It is used to collect the aggregating apparatus of medical fluid, and the aggregating apparatus another embodiment provides a kind of
Including container unit, which has at least one container for being configured for storage fluid, wherein, container unit quilt
It is pre-attached to aggregating apparatus.The ingress port with least one access road is further included in aggregating apparatus, the arrival end
Mouth is configured for receiving fluid or ambient air.Outlet port with least one exit passageway is configured to use
In transporting fluid into annex.Ingress port and outlet port are all arranged on aggregating apparatus.It is provided with for accommodating container
Unit is from the cavity of the insertion of pre-attached position, to collect the fluid from least one container.At least one pin
It is arranged in the cavity, and at least one pin is configured for when container unit is transferred to lower portion from upper position
The plug of at least one container is pierced through when putting.
In yet another embodiment, there is provided a kind of device for being used to collect medical fluid, and the device includes container
Unit, the container unit have at least one container for being configured for storage fluid, wherein, the container unit is by attached in advance
It is connected to aggregating apparatus.Ingress port with least one access road is arranged for receiving fluid or surrounding environment is empty
Gas.Outlet port with least one exit passageway is arranged for transporting fluid into annex.Ingress port and outlet
Port is all arranged on aggregating apparatus.The cavity for accommodating insertion of the container unit from pre-attached position is provided with, to
Collect the fluid from least one container.At least one pin is arranged in the cavity, and at least one pin
Nail is configured for piercing through the plug of at least one container when container unit is transferred to lower position from upper position.
Aggregating apparatus can complementally be linked relative to the longitudinal axis of each aggregating apparatus with arranged in series and another aggregating apparatus,
To establish the uninterrupted supply of the fluid of aggregating apparatus of the fluid from link.
In yet another embodiment, there is provided a kind of to be used to collect fluid from the container unit with least one container
Aggregating apparatus, and the aggregating apparatus includes the ingress port with least one access road, and the ingress port is constructed
Into for receiving fluid or ambient air.The port of export with least one exit passageway is further included in aggregating apparatus
Mouthful, the outlet port is configured for transporting fluid into annex, and ingress port and outlet port are arranged on remittance
On acquisition means.Cavity is configured for accommodating the insertion of container unit, to collect the stream from least one container
Body.At least one pin is arranged in the cavity, and at least one pin is configured for when container unit is from upper
The plug of at least one container is pierced through when being transferred to lower position in portion position.
More specifically, ingress port is fluidly coupled to the port of export via corresponding pipe and at least one pin
Mouthful, and at least one pin has the first pin passage for being connected at least one access road.It is in addition, described
At least one pin has the second pin passage for being connected at least one exit passageway.In ingress port and outlet port
It is at least one there is protection cap, to protect corresponding access road and exit passageway from pollution, and described at least one
A pin is vertically protruded from the inner surface of the base portion of aggregating apparatus.
Locking mechanism is set for aggregating apparatus, and the locking mechanism is configured for container unit during use
It is firmly held in cavity, and locking mechanism is preferably provided on the inner wall of cavity.The cavity is configured for holding
The insertion of container unit is received, to collect the fluid from single container.At least one container is configured to storage fluid, and
Container unit is attached to aggregating apparatus.Lockable mechanism is set for aggregating apparatus, and the lockable mechanism is configured for
Container unit is prevented to be transferred to lower position from upper position.
For container unit, include lock pin, and the lock pin is inserted into being arranged on the body of container unit
On slot in.Press strip is provided with the top of container unit, makes container unit from top by pushing down on the press strip
Position transfer is to lower position.Advantageously, aggregating apparatus can be connected with another aggregating apparatus with complementary relationship and be linked, and be used
To establish the uninterrupted supply of the fluid of the aggregating apparatus from link.Preferably, the ingress port of the first aggregating apparatus is by structure
Cause to be inserted into complementary relationship in the outlet port of the second aggregating apparatus.First aggregating apparatus and the second aggregating apparatus phase
Linked together for the longitudinal axis of each aggregating apparatus with complementary relationship series connection.
Be provided with cap remover for aggregating apparatus, and the cap remover be attached at least one container and by
It is configured to the top cap for removing at least one container.Anti-leakage mechanism has：Fluid connection assembly, it is configured to use
In controlling the fluid path in aggregating apparatus；And component is air connected, it is configured for logical in control aggregating apparatus
Gas circuit footpath.Being air connected component includes air path connector, which is connected to remittance via hydrophobic filter
The ingress port of acquisition means.
Include first fluid check-valves and second fluid check-valves in fluid connection assembly, the first fluid check-valves quilt
The outlet port of aggregating apparatus is connected to, to be selectively adjusted the flowing of the orientation fluid of fluid, the second fluid check-valves
The ingress port of aggregating apparatus is connected to, to be selectively adjusted the flowing of the orientation fluid of fluid.First fluid check-valves
With first fluid path connector, which is configured to be releasably connected in complementary fashion another
The second check-valve of one aggregating apparatus, and second fluid check-valves has second fluid path connector, the second fluid
Path connector is configured to be releasably connected to the first fluid check-valves of another aggregating apparatus in complementary fashion.First
Opening pressure with second fluid check-valves is in the scope of 3-5 pound per square inches.
Include air path connector or end piece component with blind chamber, the air path connector being air connected component
Or end piece component is configured to be releasably connected to the air path connector of another aggregating apparatus in complementary fashion.
Fluid connection assembly includes the first female component with the first female member openings, which is configured to
Insertion for the first male member for accommodating fluid connection assembly.Moreover, fluid connection assembly includes component locking mechanism, should
Component locking mechanism is configured for being releasably attached the first female component and male member of fluid connection assembly.Specifically
For, the first female component has the first sealing clamp, which is configured for preventing the oriented flow of fluid
Body flows, and the first male member has the second sealing clamp, which is configured for preventing fluid
Orient fluid flowing.In addition, the first female component has the column to dangle from the inside upper surface of the first female component, and first
Male member has supporting bead, which has central through hole, which is sized to receive the first female
The insertion of the column of component.The second female component with the second female member openings is further included in component is air connected, this
Two female member openings are configured for accommodating the insertion for the second male member for being air connected component.
Hydrophobic filter is arranged in the second female member openings of the second female component, and the second male member quilt
It is configured to for forming airtight interference fit between sheath and the second female component.Preferably, the second male member is had
The sheath for having annular projection surrounds.Multiple fluids and air path pipeline are arranged in aggregating apparatus, and the path tube
What road was constructed and arranged to make in the ventilation path and fluid path of aggregating apparatus at least one is in fluid communication with each other.
Preferably, it is air connected component and is connected at least two containers of aggregating apparatus at the same time and by described at least two
A container shares, and fluid connection assembly includes the first power actuating valve, and first power actuating valve is connected to aggregating apparatus
Outlet port, to be selectively adjusted the bi-directional fluid flow of fluid.In addition, fluid connection assembly is activated including the second power
Valve, second power actuating valve is connected to the ingress port of aggregating apparatus, to be selectively adjusted the orientation fluid stream of fluid
It is dynamic.Include one way stop peturn valve in fluid connection assembly, which is connected to the ingress port of aggregating apparatus, to
It is selectively adjusted the orientation fluid flowing of fluid.
At least one pin is surrounded by pin sheath, which is configured for the ingress port of aggregating apparatus
Communication is connected with outlet port.Fluid connection assembly includes pin connector and access dome valve.Specifically, access
Dome valve has opening, which is configured for accommodating the insertion of pin connector with complementary relationship.Fluid connection assembly
Including at least one in hydrophobic filter and hydrophilic filter.Preferably, hydrophobic filter is connected to aggregating apparatus
Ingress port, to be selectively adjusted the orientation air flow of aggregating apparatus.Alternatively or additionally, hydrophilic filter quilt
The outlet port of aggregating apparatus is connected to, to be selectively adjusted the flowing of the orientation fluid of aggregating apparatus.
Tray component includes at least one aggregating apparatus that fluid flow communication is attached in tray component.Preferably, pallet
Component includes flowing and covers, which has at least one flow passage and be attached to tray component to promote fluid to connect
It is logical.In addition, tray component includes normal valve, which is configured for being selectively adjusted from least one container
Flow path.At least one hydrophobic filter is connected at least one in ingress port and outlet port.Similarly, at least
One hydrophilic filter is connected at least one in ingress port and outlet port.In another embodiment, pallet structure
Part includes multiple aggregating apparatus that fluid flow communication is attached in tray component.In this configuration, it is preferred that tray component bag
Two independent pipes are included, which is configured for two kinds of independent fluids are defeated from the multiple aggregating apparatus
It is sent to outlet port.
In yet another embodiment, there is provided a kind of aggregating apparatus for being used to collect medical fluid, and the aggregating apparatus
Including container unit, which has at least one container for being configured to storage fluid, which is attached to
Aggregating apparatus.Ingress port has at least one access road, which is configured for receiving fluid
Or ambient air.Outlet port has at least one exit passageway, which is configured for conveying fluid
To annex, wherein ingress port and outlet port is arranged on aggregating apparatus.Cavity is configured for accommodate container unit
Insertion, to collect the fluid from least one container.At least one pin is arranged in the cavity, and should
At least one pin is configured for piercing through when container unit is transferred to lower position from upper position described at least one
The plug of container.Aggregating apparatus can be relative to each aggregating apparatus with arranged in series and another aggregating apparatus complementation ground chain
Connect, to establish the uninterrupted supply of the fluid of the aggregating apparatus from link.First wing and are further included in aggregating apparatus
Two wings, first wing are configured for accommodating outlet port, which is configured for accommodating ingress port.Second wing
Shifted vertically relative to first wing.
It is considered in conjunction with the accompanying described in detail below, the skill of foregoing and the other aspect and feature of the disclosure for this area
Art personnel will become obvious.
Brief description of the drawings
Fig. 1 is the perspective view of the first embodiment of the aggregating apparatus of the present invention, depicts exemplary double containers for medical use units
With exemplary ejection pipe fitting group；
Fig. 2 is the plan of the aggregating apparatus of Fig. 1, depicts the Exemplary portals port for fluid conveying and the port of export
Mouth and the integration pin for being laterally positioned in the plug on the inner surface of aggregating apparatus for the corresponding containers for medical use of puncture
Nail；
Fig. 3 is the partial plan layout of the aggregating apparatus of Fig. 2, is depicted on the outer surface for be arranged on aggregating apparatus for can
Releasably it is connected to the exemplary outlet port of injection pipe fitting group；
Fig. 4 is the perspective view of the second embodiment of the aggregating apparatus of the invention with lock pin, is shown in connection
The exemplary arrangement of two preceding adjacent aggregating apparatus；
Fig. 5 is the perspective view of the aggregating apparatus of Fig. 4 after connection；
Fig. 6 is the front schematic view of the aggregating apparatus of Fig. 5, depicts the fluid path between the containers for medical use of connection
Graphical representation of exemplary；
Fig. 7 is the side view of the 3rd embodiment of the aggregating apparatus of the present invention, and showing has for lock pin and enter
Another exemplary arrangement of the aggregating apparatus of two connections of the different configuration of mouth port and outlet port；
Fig. 8 is the rear view of the aggregating apparatus of Fig. 7 when adjacent aggregating apparatus interconnection；
Fig. 9 is the rear view of the aggregating apparatus of Fig. 7 when adjacent aggregating apparatus disconnects；
Figure 10 is the front schematic view of the aggregating apparatus of Fig. 5, depicts with fluid connection assembly and is air connected group
The anti-leakage mechanism of part；
Figure 10 A are the front schematic views of the anti-leakage mechanism of Figure 10, depict the example combinations of two power actuating valves；
Figure 10 B are the front schematic views of the anti-leakage mechanism of Figure 10, depict power actuating valve and one way stop peturn valve shows
Example property combination；
Figure 10 C are the front schematic views of the anti-leakage mechanism of Figure 10, depict pin connector and access dome valve
Example combinations；
Figure 11 is the signal of the aggregating apparatus of Figure 10 when adjacent aggregating apparatus is connected with each other via anti-leakage mechanism
Property front view；
Figure 12 is the decomposition partial vertical section of the fluid connection assembly of Figure 10；
Figure 13 is the decomposition partial vertical section for being air connected component of Figure 10；
Figure 14 is the vertical cross-section of the anti-leakage mechanism of Figure 10, shows the fluid path of fluid connection assembly；
Figure 15 is the bottom view of the anti-leakage mechanism of Figure 10；
Figure 16 is configured for the bottom view of the anti-leakage mechanism of Figure 10 for promoting double containers for medical use units；
Figure 17 A are configured to the top perspective view for the exemplary cap remover being used together with the aggregating apparatus of Fig. 1；
Figure 17 B are the bottom perspective views of the cap remover of Figure 17 A；
Figure 17 C- Figure 17 D show the example of use of the cap remover of Figure 17 A；
Figure 18 is the front schematic view of the anti-leakage mechanism of Figure 10, depicts showing for hydrophobic filter and hydrophilic filter
Example property combination；
Figure 19 is the decomposition diagram for the exemplary tray that the aggregating apparatus of the present invention is combined with arranged in series；And
Figure 20 is the decomposition diagram of example modules unit, and depict with hydrophobic filter of the invention collects dress
Put.
Embodiment
Although the specific embodiment of the aggregating apparatus of the present invention already described herein, the aggregating apparatus with the present invention
Other alternate embodiments of relevant all components are interchangeable to adapt to different applications.The term used in this application
" aggregating apparatus " refer to for from one or more containers for medical use access medical fluid so as to by medical fluid infusion to patient's
Device.It is therefore contemplated that it is used for the aggregating apparatus for being transfused medical fluid from single container and multiple containers for medical use.
Referring now to Fig. 1-Fig. 3, this aggregating apparatus is designated generally by 10, and is designed to be labeled on the whole
Collect medical fluid or material for 12 containers for medical use unit, which has the first containers for medical use 14 and the second doctor
With container 16, which is configured for the first medical fluid of storage, which is constructed
Into for storing the second medical fluid.In certain embodiments, aggregating apparatus 10 of the invention is disposable unit, to avoid weight
Caused potential pollution is used again.As described above, described in commonly assigned U.S. Patent number 8,684,433 exemplary double
Containers for medical use unit 12, the United States Patent (USP) are incorporated herein by reference.While it is contemplated that other medical substances and the present apparatus 10 1
Rise and use, but in one embodiment, the first containers for medical use 16 accommodates the enzyme of the hole in the subcutaneous space for expanding patient.Hole
Expansion contribute to the large volume being contained in second container 14 relatively highly viscous IG fluids injection delivery.For example,
In the case of not having enzyme, it is about 50ml that the expection of IG fluids, which is injected at single position,.However, using the enzyme, can be in single note
Injection in the scope of 600ml can be realized by penetrating position.
Though it is shown that the container unit 12 with two containers for medical use 14,16, but also contemplate container unit tool
There is single container (for example, injection tube, bottle, bag film, ampoule etc.).In one embodiment, when viewed from above, this hair
Bright aggregating apparatus 10 has substantially rectangular shape, it is contemplated however that other suitable shapes, such as ellipse, square and
Other geometries.The remittance of the present invention can be used for by also contemplating any combinations of any quantity containers for medical use or containers for medical use
Acquisition means 10, to adapt to different applications.
Include ingress port 18 in the aggregating apparatus 10 of the present invention, which is configured for receiving medicinal
Fluid or ambient air, and the ingress port is arranged on the outer wall 20 of aggregating apparatus.In certain embodiments, it is as follows
As the more detailed description of face, when aggregating apparatus is linked together, ingress port 18 is received from adjacent aggregating apparatus
The medical fluid of (Fig. 4 and Fig. 5).Alternatively, ingress port 18 is not when aggregating apparatus 10 is linked to adjacent aggregating apparatus
Serve as the ventilating opening for extracting ambient air.As shown in below with reference to Fig. 6, linked together when by aggregating apparatus 10
When, it has been found that the appropriate ventilation between corresponding device and container improves the sequentially-fed of medicament.Depending on container
The construction of unit 12, ingress port 18 can have one or more access roades 22,24, one or more of access roades
22nd, 24 is corresponding with containers for medical use 14,16 during use.
In order to from 10 transporting medicinal liquids of aggregating apparatus, output port 26 be arranged on the outer wall 20 of aggregating apparatus with entering
On the opposite side in mouth port 18, and output port 26 is configured to medical fluid being transported to another medical annex, all
Such as adjacent aggregating apparatus or injection pipe fitting group 28.In certain embodiments, pipe fitting group 28 is injected at one end removably to connect
The outlet port 26 of aggregating apparatus 10 is connected to, and the pumping system of such as peristaltic pump is detachably connected in opposite end
(not shown) or injection device, to extract medical fluid from aggregating apparatus 10.Alternately, can be by injection tube (not shown)
Outlet port 26 is docked to, medical fluid will be evacuated from aggregating apparatus 10.
The flow for adjusting the medical fluid in pipe fitting group 28 be by the longitudinal axis relative to corresponding pipe fitting laterally
At least one pipe clamp 30 is adjusted to realize.As known in the art, it is contemplated to occlusion locations and non-blocking position it
Between other folders for shifting close device.As the situation of ingress port 18, outlet port 26 can have one or more outlets to lead to
Road 32,34, one or more of exit passageways 32,34 are corresponding with containers for medical use 14,16 during use.
In certain embodiments, each passage 22,24,32,34 have positioned at corresponding passage inlet can elasticity
The seal 36 of deformation, O-ring etc., to promote between the ingress port 18 of connection and outlet port 26 or export
Frictional fit between port 26 and injection pipe fitting group 28 is slidably connected.Removable 38 frictional fit of protection cap is contemplated to exist
On each port 18,26 or surrounding, to prevent corresponding access road and exit passageway 22,24,32,34 from being touched or air
Pollution.
In certain embodiments, the central opening or chamber for the insertion for being configured for accommodating containers for medical use unit 12 are set
Body 40, to collect the first and second medical fluids from the first and second containers for medical use 14,16.By containers for medical use unit
Before 12 are inserted into cavity 40, the top cap 42 of containers for medical use unit is removed to expose corresponding first and second container 14,16
The first and second plugs 44,46.The terminal sterilization of plug 44,46 is come using the disinfectant of alcohol, hydrogen peroxide etc.
Carry out.
First inner chamber pin or pin 48 are arranged in cavity 40, for piercing through the first plug 44 of the first containers for medical use 14,
And second inner chamber pin or pin 50 are arranged in chamber, for piercing through the second plug 46 of the second containers for medical use 16.Two pins
48th, 50 be preferably laterally integratedly attached to aggregating apparatus 10 base portion 54 inner surface 52 so that pin is vertically dashed forward from base portion
Go out, simultaneously to pierce through the first and second plugs 44,46 of corresponding first and second containers for medical use 14,16.In some situations
In, the first and second plugs 44,46 of corresponding first and second containers for medical use 14,16 are dividually pierced through different to adapt to
Using.In certain embodiments, the removable sleeve or sheath 56 that protectiveness is provided for each pin 48,50 are each sold with covering
The tip point of nail.
Beginning by for medical fluid conveying reverses container unit 12 and container unit is inserted into cavity 40, makes
Container unit from upper position is transferred to lower position to realize.Specifically, in the illustrated embodiment, in the insertion phase
Between, the first and second plugs 44,46 of the first and second containers 14,16 be pressed against the first and second inner cavity pins 48,
Pierced through on 50 and by the first and second inner cavity pins 48,50.The protection provided by sleeve 56 is be provided and is sealed in container list
The reversing of member 12 and while being downwardly into, are destroyed.The folder for the biasing being arranged in the illustrated embodiment on the inner wall 60 of cavity 40
Piece or clamp-type locking mechanism 58 are arranged to be used for container unit 12 being maintained at 54 top certain space of base portion so that container
14th, 16 pin 48,50 cannot be reached, unless container is correctly positioned above appropriate pin.
It is properly oriented within for the ease of container in unit 12, as shown in Fig. 2, cavity 40 is sized so that container
Unit 12 is by key connection to cavity so that container unit 12 can be only inserted into being correctly oriented.Once container 14,16 is correct
Ground is positioned in cavity 40, and locking intermediate plate 58 is radially outward pushed due to the presence of container, this allows 12 phase of container unit
Collapse, slide or move down for base portion 54, so as to realize engagement between container and the pin specified 48,50.Pin 48,
50 pierce through the plug 44,46 of corresponding container 14,16, and start the corresponding conveying for accommodating medical fluid.
In order to promote the fluid of the first medical fluid to convey, the first pin 48 has the first pin passage 62, first pin
Nail channel 62 is connected to first entrance passage 22 via corresponding pipe fitting 64.In addition, the first pin 48 has the second pin passage
66, which is connected to first outlet passage 32 via corresponding pipe fitting 64.In a preferred embodiment, at least one
A check-valves 68 is inserted into or optionally controls the directed flow of medical fluid in pipe fitting 64.It is contemplated that
Term " pipe (tube) " or " pipe fitting (tubing) " include or be related to be separated or integral times with the aggregating apparatus 10 of the present invention
That what is fixed or flexible fluid passage or path, such as groove etc., it depends on application with building method and with various sections
Face shape (for example, circular, square or other shapes).
Contemplate pipe fitting 64 to be configured to ingress port 18, pin 48,50 and outlet port 26 being connected with each other, such as ability
As known in domain.As a result, when activating aggregating apparatus 10, established and first from ingress port 18 to outlet port 26
The continuous flow path that container 14 is in fluid communication.It is more fully described Ru following in the paragraph related with such as Figure 10-Figure 16
, it is also contemplated that hydrophobic filter is used in other suitable positions of pipe fitting 64 or aggregating apparatus 10, to allow air to lead to
Cross, but prevent medical fluid from being leaked from aggregating apparatus.Other check-valves may be mounted at the lower section of base portion 54, medicinal to prevent
Fluid advances to the adjacent cells of connection via pin 48,50.
More specifically, as shown in Fig. 2, being not linked to the structure of another aggregating apparatus in aggregating apparatus 10 of the invention
In making, ambient air is sold under the action of pumping system via first entrance passage 22, corresponding pipe fitting 64 and first
First pin passage 62 of nail 48 is sucked into the first container 14 (shown in broken lines in fig. 2).As a result, in the first container 14
The first medical fluid be transported to first outlet via the second pin passage 66 and corresponding pipe fitting 64 of the first pin 48 and lead to
Road 32.The exemplary flowpath of air and the first medical fluid is represented with dotted arrow A.
When the conveying of the first medical fluid is completed, can be started by controlling the opening and closing (Fig. 3) of pipe clamp 30
The conveying of second medical fluid.In order to promote the fluid of the second medical fluid to convey, the second pin 50 has the first pin passage
70, which is connected to second entrance passage 24 via corresponding pipe fitting 64.In addition, the second pin 50 has the
Two pin passages 72, the second pin passage 72 are connected to second outlet passage 34 via corresponding pipe fitting 64.Therefore, activating
During aggregating apparatus 10, establish from ingress port 18 to outlet port 26 and connect with second container 16 (shown in broken lines in Fig. 2) fluid
Logical continuous flow path.
Specifically, as the situation of the first pin 48, ambient air is under the action of pumping system via
Two access roades 24, the first pin passage 70 of 64 and second pin 50 of corresponding pipe fitting are sucked into second container 16.
As a result, 64 quilt of the second pin passage 72 and corresponding pipe fitting of the second medical fluid in second container 16 via the second pin 50
It is transported to second outlet passage 34.The exemplary flowpath of air and the second medical fluid is represented with dotted arrow B.
Referring now to Fig. 2 and Fig. 4-Fig. 6, another embodiment of aggregating apparatus 10 of the invention is designated generally by
74a、74b、74c.In Fig. 4-Fig. 6, the corresponding component attached drawing mark of first, second, and third aggregating apparatus 74a, 74b, 74c
Note is represented plus first three alphabetical (i.e. " a ", " b " and " c ") label.With the identical attached drawing of the shared component of aggregating apparatus 10
Mark represents.In specific embodiment shown in aggregating apparatus 74a, 74b, 74c, there are the first and second containers 14,16
Containers for medical use unit 12 is attached to aggregating apparatus 74a, 74b, 74c as prefabricated unit.
More specifically, the first and second plugs 44,46 of container 14,16 are inserted into aggregating apparatus 74a, 74b, 74c
Cavity 40 in, and prepare by the first and second pins 48,50 (Fig. 2) pierce through.The present invention aggregating apparatus 74a, 74b,
In 74c, it is contemplated to carry out terminal sterilization to each device 74 by γ radiation etc. to ensure sterile fluid path.Pin
48th, 50 protective sheath 56 is equipped with, when container 14,16 is pressed, protective sheath 56 is pierced and compresses, thus before the use
Keep pin clean and keep fluid path sterile.
Then, device 74 and container unit 12 are assembled and are sealed in ventilative packaging, and with such as peroxidating
The disinfectant processing of hydrogen steam etc., plug 44,46 and pin 48,50 are kept the state in disinfection before the use.
In such configuration, be prepositioned or be pre-positioned in will quilt for the first and second plugs 44,46 of container 14,16
In the upper position that first and second pins 48,50 pierce through.However, it is configured for preventing container unit 12 from upper position
Being transferred to the lockable mechanism of lower position or pin 76 prevents (for example, during transport and processing) before the use premature activation from converging
Acquisition means 74a, 74b, 74c.Therefore, pin 76 performs the function similar to locking intermediate plate 58 discussed above.Contemplate lock pin
76 are inserted into the slot 78 on the body 80 for the container unit 12 being arranged between the first and second containers 14,16, still
Contemplate other suitable constructions of lock pin.
After lock pin 76 is departed from by the way that lock pin 76 is pulled out from body 80, at the top of container unit 12
It is upper setting press strip 82, the press strip 82 have be used for grasp enhancing purpose multiple grooves 84, and push down on press strip 82 so that
Container unit is transferred to lower position from upper position.This of container unit 12 moves down the first and for causing container 14,16
Second plug 44,46 is pierced through by corresponding first and second pin 48,50.
In some embodiments of the aggregating apparatus of the present invention, in embodiment as in the depicted, 74a, 74b, 74c, two
A or more aggregating apparatus can be linked together relative to the longitudinal axis of each aggregating apparatus with complementary relationship series connection, be used
To establish the uninterrupted supply of medical fluid from the aggregating apparatus linked.For example, as shown in Figure 4 and Figure 5, the first aggregating apparatus
The ingress port 18a of 74a is inserted into the outlet port 26b of the second aggregating apparatus 74b and is complementary to connect.Second collects
The ingress port 18b of device 74b is then inserted into the outlet 26c of the 3rd aggregating apparatus 74c, collects dress with promote all-links
Put the uninterrupted connection of the fluid path between 74a, 74b, 74c.
In this configuration, first, second, and third aggregating apparatus 74a, 74b, 74c is connected or chain with being in fluid communication with each other
Connect, to provide the path of the uninterrupted continuous conveying for medical fluid between aggregating apparatus.For example, linked first
The first medical fluid of container 14a, 14b, 14c can be transfused to user in the case where not interrupting or not manipulating container.Class
As, the second medical fluid of second container 16a, 16b, 16c for being linked can then be transfused to user.Contemplate and collect
Device 74a, 74b, 74c can be arranged in any other suitable way, to promote the infusion of medical fluid.In addition, the first He
Second medical fluid can be conveyed to user in reverse order to adapt to apply.
Referring now to Fig. 5 and Fig. 6, for illustrative purposes, show band be useful for three links the first container 14a,
The embodiment of the flow path of 14b, 14c.In this configuration, ambient air is via ingress port 18c and the first pin 48c
The first pin passage 62c be sucked into right side the first container 14c in.The second pin passage 66c of first pin 48c is connected
The first pin passage 62b for the first pin 48b being connected in the first container 14b of centre.Similarly, the of the first pin 48b
Two pin passage 66b are connected to the first pin passage 62a of the first pin 48a in the first container 14a on the left side.
Then, the second pin passage 66a of the first pin 48a in Fig. 6 via showing on the left side of the first container 14a
Outlet port 26a is connected to pumping system.Another flow path of second container 16a, 16b, 16c of three links are with similar
Mode establish.
In operation, caused to come from three first by the port 26a negative pressure produced or swabbing pressure by pumping system
The uninterrupted sequentially-fed of the first medical fluid of container 14a, 14b, 14c.System 74a-c has built-in air/fluid pipe
Feature is managed, for providing the sequentially-fed of the medicament from cell therefor 14a-c.For example, initially, the first container in left side
The swabbing pressure for the fluid contents that fluid in 14a is applied to container 14a via port 26a and pin passage 66a is downward
Suction, vacuum is produced above the level of the fluid in container 14a.The foundation of the vacuum pressure is via pin passage
62a and access road 18a to exit passageway 26b and fluidly connecting for pin passage 66b and the fluid contents of container 14b are produced
Raw suction pressure.
Next, the swabbing pressure on the fluid contents being applied in the first container 14b of centre is downward by inclusion
Suction, until the horizontal top of fluid in this embodiment forms similar vacuum.Once produced in two containers 14a and 14b
Raw vacuum, just via pin passage 62b and access road 18b to exit passageway 26c and fluidly connecting for pin passage 66c and
Swabbing pressure is produced on the fluid contents of container 14c.Due to container 14c by pipeline 18c to surrounding environment ventilation, so
Slight vacuum pressure is only produced above the fluid contents of container 14c.On the contrary, the swabbing pressure produced will lead to via pin
Road 62c and ingress port 18c and environment, and air will be caused to be sucked into container 14c, and the container
To be emptying first.
Container 14c will be empty, until liquid level is reached below the entrance of pin passage 66c, thus next container 14b
Inside will be exposed to surrounding environment via container 14c, so as to allow the fluid contents of container 14b in the suction force of pumping system
Under the action of be drained.Finally, after container 14b is drained, then container 14a is drained in a similar way.Therefore, three
A container 14a, 14b, 14c are sequentially transfused automatically with order from far near, until all containers are all empty.
The different cubical contents of each container 14a, 14b, 14c do not interfere with the fluid delivery process of the order.Standard vial
Exemplary cubical content include 25 milliliters, 50 milliliters, 100 milliliters, 200 milliliters and 300 milliliters, it is contemplated that any other conjunction
Suitable size or the containers for medical use of combination.Referring now to Fig. 2 and Fig. 7-9, another (3rd) of aggregating apparatus 74 of the invention
Embodiment is designated generally by 86a, 86b.In Fig. 7-Fig. 9, the corresponding component of first and second aggregating apparatus 86a, 86b is used
Reference numeral is represented plus the first two alphabet (i.e. " a " and " b ") label.With the component that aggregating apparatus 74 shares with identical attached
Icon note represents.Main distinguishing feature in aggregating apparatus 86a, 86b is that aggregating apparatus is relative to the vertical of each aggregating apparatus
Linked to axis with serial arrangement or chrysanthemum links together.
More specifically, each aggregating apparatus 86a, 86b include first or left wing 88a, 88b and second or right flank 90a,
90b, this first or left wing 88a, 88b be configured for accommodating outlet port 26a, 26b, this second or right flank 90a, 90b quilt
It is configured to be used to accommodate ingress port 18a, 18b.On the first aggregating apparatus 86a shown in Fig. 9, first entrance passage 22a
It is arranged on second entrance passage 24a on the second wing 90a, first outlet passage 32a and second outlet passage 34a are arranged on first
On wing 88a.Second aggregating apparatus 86b has the same configuration for corresponding access road and exit passageway.
As shown in Figure 8 and Figure 9, in order to establish the daisy chain connection of two adjacent aggregating apparatus 86a, 86b, first collects
The first wing 88b of the second wing 90a and the second aggregating apparatus 86b of device 86a are complementally connected.More specifically, preferred real
Apply in example, the second wing 90a is relative to the axis location of the longitudinal axis transverse to aggregating apparatus 86a, 86b into higher than first wing
88b.Contemplate the relative position of first and second wing 88b, 90a and be configured to opposite with above-mentioned orientation.
It is also preferred that first entrance passage 22a and second entrance passage 24a prolongs downwards from the lower surface of the second wing 90a
Stretch, and first outlet passage 32b and second outlet passage 34b is upwardly extended from the upper surface of the first wing 88b.Therefore, pass through
By the second wing 90a of the first aggregating apparatus downward onto on the first wing 88b of the second aggregating apparatus so that the first aggregating apparatus
Access road 22a, 24a be inserted into exit passageway 32b, 34b of the second aggregating apparatus and realized with complementary arrangement
The daisy chain connection of aggregating apparatus 86a, 86b.
Return to Fig. 2, Fig. 7 and Fig. 9, aggregating apparatus 86a, 86b another feature is that, protection cap 38 has elongated
Body, the slender body are configured to accommodate first wing and the shape or profile of right flank 88a, 88b, 90a, 90b.Alternatively, protect
Lid 38 has auxiliary port 92, which is configured for passing through medical fluid from container 16a and 16b corresponding
Outlet port 26a, 26b, which is transported to, to be for example docked in the injection tube of auxiliary port 92.Protection cap 38 also has pipe fitting group, the pipe
Part group be configured for by the medical fluid delivery from other container 14a and 14b to the syringe pump for being connected to patient with
Injected.Instead of lock pin 76 (Fig. 5), locking spacer 94 is set to prevent container unit 12 to be transferred to lower position.Most
Just, locking spacer 94 is inserted into the annular for the circumferentially extending being arranged on the top 98 of corresponding aggregating apparatus 86a, 86b
In groove 96, container unit 12 is locked in upper position.
Similarly operated with lock pin 76, by pull be attached to the ring 100 of distance piece by locking spacer 94 from
After aggregating apparatus 86a, 86b are removed, the press strip 82 of container unit 12 is pushed down on so that container unit is shifted from upper position
To lower position.This move down of container unit 12 causes the first and second plugs 44,46 of container 14,16 corresponding
First and second pins 48,50 pierce through.
Referring now to shown in Fig. 2, Fig. 6 and Figure 10, exemplary anti-leakage mechanism is designated generally by 102, and by
It is designed to prevent undesirable air or fluid from leaking from aggregating apparatus 10.With the component that aggregating apparatus 10 shares with identical attached
Icon note represents.The fluid connection assembly that includes being designated generally by 104 in anti-leakage mechanism 102 and generally labeled
Component is air connected for 106, which is configured for the fluid path in control aggregating apparatus 10, the sky
Gas connection component is configured for the ventilation path in control aggregating apparatus.The anti-leakage mechanism 102 is contemplated to can be applied to
All embodiments of above-mentioned aggregating apparatus 10,74,86.
In a preferred embodiment, fluid connection assembly 104 includes first fluid valve 108, and the first fluid valve 108 is by one
Into the outlet port 26 of the first aggregating apparatus 74, to be selectively adjusted the fluid of the medical fluid from the first container 14
Flowing.When first fluid valve 108 is not linked to another device or Tube jointer, first fluid valve 108 is normally closed
, and when first fluid valve 108 is connected to another device or tube connector, first fluid valve 108 be mechanically opened with
Fluid is allowed to be flowed via connector 114.Fluid connection assembly 104 includes second fluid check-valves 110, the second fluid non-return
Valve 110 is connected to the ingress port 18 of the first aggregating apparatus 74, to be selectively adjusted the medicinal stream of the first container 14
The orientation fluid flowing of body.
It is check valve to contemplate fluid check valve 110, it allows the fluid path for being only oriented towards the first container 14 so that when
One and second fluid check-valves when being in resting position, the medical fluid in the first container will not let out from container.First
Valve 108 has first fluid path connector 112, which is configured in complementary fashion
It is releasably connected to the second check-valve 110 of another aggregating apparatus.Alternatively, second check-valve 110 has second fluid
Path connector 114, the second fluid path connector 114 are configured for being releasably connected in complementary fashion another
The first check-valve 108 of a aggregating apparatus.
During use, first fluid valve 108 prevents the fluid when aggregating apparatus 74 is not connected to another aggregating apparatus
Flowed from the first container 14.The valve is mechanically opened when being connected to another device 74, to allow free fluid to flow.Second
Fluid check valve 110 is prevented when device 74 is not linked to another aggregating apparatus from the leakage of connector 114, and is also prevented
Undesirable leakage between the aggregating apparatus 74 of connection.The exemplary Opening pressure of fluid check valve 110 is about 3-5 pounds every
Square inch (PSI), to allow to open valve by the Fluid pressure that the pump by connecting produces.
In order to be selectively adjusted the orientation air flow of aggregating apparatus 74, being air connected component 106 includes air path
Connector 116, the air path connector 116 are connected to the ingress port of the first aggregating apparatus 74 via hydrophobic filter 118
18.Specifically, hydrophobic filter 118 is connected to air path connector 116 at one end, and is connected in opposite end
Pin 48 in 110 downstream of fluid check valve.As it is known in the art, hydrophobic filter 118 allows air to pass through but anti-fluid stopping
Body passes through filter.Therefore, hydrophobic filter 118 prevents medical fluid from undesirably being leaked from air path connector 116.Can
Alternatively, it is also contemplated that other suitable hydrophilic filters are to adapt to different applications.
Air path connector or end piece 120 with blind chamber 122 are provided with component 106 is air connected, and
The air path connector or end piece 120 are configured for being releasably connected to another aggregating apparatus in complementary fashion
Air path connector 116.When air path connector 120 matchingly or is complementally connected with air path connector 116,
Ventilation path in aggregating apparatus 74 is blocked or is blocked by blind chamber 122, thus effectively prevents air from leaking.
Referring now to Fig. 2, Fig. 6 and Figure 11, it is contemplated to which the first aggregating apparatus 74a is linked or chrysanthemum is linked to second and collects
Device 74b (Figure 11).The corresponding component of anti-leakage mechanism 102a, 102b and first and second aggregating apparatus 74a, 74b are with attached
Icon note is represented plus alphabetical (i.e. " a " and " the b ") label of the first two.In this configuration, the second sky for being air connected component 106b
Gas circuit footpath connector 120b is matched ground or is complementally connected to the first air path connector 116a for being air connected component 106a.
Therefore, when first and second aggregating apparatus 74a, 74b links or chrysanthemum link, except the farthest side in the device of chrysanthemum link
Device ventilation path (for example, the vent passage limited by the second air path connector 116b for being air connected component 106b
Footpath) outside, the ventilation path of the aggregating apparatus of connection closes automatically or obstruction.
As for fluid path, the first fluid path connector of the first fluid valve 108b of second fluid connection component 104b
112b is matched ground or is complementally connected to the second fluid of the second fluid check-valves 110a of first fluid connection component 104a
Path connector 114a.Also contemplate pumping system and be connected to the first fluid connection component being in fluid communication with container 14a
The first fluid path connector 112a of the first fluid valve 108a of 104a.
In this configuration, first valve 108a, 108b of connection by first fluid path connector 112a, 112b mechanically
Open, to allow the fluid communication between pumping system and aggregating apparatus 74a, 74b.However, second check-valve 110a, 110b
All need not mechanically it open, because unidirectional second check-valve 110a has been provided for converging from the second aggregating apparatus 74b to first
The fluid flowing of acquisition means 74a.First valve 108a, 108b of fluid outflow container 14a, 14b is not only allowed mechanically to be beaten
Open.
Describe as similarly described above, ambient air is via the air path connector 116b for being air connected component 106b
It is sucked into hydrophobic filter 118b in the container 14b of the second aggregating apparatus 74b.Meanwhile second aggregating apparatus 74b second
The second check-valve 110b of fluid connection assembly 104b prevents fluid from being leaked from container 14b.As a result, produced by pumping system negative
Pressure (such as vacuum) causes the uninterrupted sequentially-fed of the medical fluid from container 14a, 14b, is not intended to flow without any
Body leaks.
Referring now to shown in Figure 10 and Figure 12, it is preferred that fluid connection assembly 104 includes having female member openings
126 female component 124, it is configured to the insertion for accommodating the male member 128 of fluid connection assembly.In order to by female component
124 are fixedly attached to male member 128, in fluid connection assembly 104 set be designated generally by 130 it is snap-fitted
Component locking mechanism, and the snap-fitted component locking mechanism is configured for female component 124 and male member 128
It is releasably coupled together.
In a preferred embodiment, locking mechanism 130 includes being arranged on the inner surface of side wall 134 of female component 124
At least one lock tabs or projection 132 and at least one depression or the groove being arranged on the outer surface of male member 128
136.When male member 128 is slidably inserted into female member openings 126,132 He of lock tabs of locking mechanism 130
Corresponding depression 136 female component 124 and male member 128 are firmly held in place, is thus opened by ordinatedly breech lock
The orientation fluid flowing of medical fluid indicated by beginning arrow C.Contemplate other locking mechanism structures, such as annular locking and
Discharge groove, flank etc..
One importance of fluid connection assembly 104 is, female component 124 has the first sealing clamp 138, first
Sealing clamp 138 is attached to the external upper of female component, for providing the compression seal of Fluid Sealing.It is close to contemplate first
Binder tool 138 has the first concave side 140 and the first opposite convex side 142, and the seal is designed to when pressure is applied to
It is opened when in the first concave side or convex side 140,142.Preferably, the first sealing clamp 138 has a general dome shape, and by
Flexible elastomeric material is made.Contemplate the first slit with predetermined length or gap 144 is arranged on the first sealing clamp
138 approximate center so that slit tight closure when static, but when pressure be applied to the first concave side or convex side 140,
Opened when on 142.
More specifically, when the first sealing clamp is in resting position, the first slit 144 of the first sealing clamp 138
Prevent the fluid of medical fluid from flowing.However, when the negative pressure produced by pumping system is applied to the convex side of the first sealing clamp 138
When 142, the first slit 144 is opened to allow the fluid of medical fluid to flow, as shown in arrow C.Contemplate other suitable classes
The check-valves of type, such as spring-loaded ball check valve, duckbill valve, umbrella valve, diaphragm valve etc., to adapt to apply.
Also contemplating female component 124 has tubular post 146, the female of the tubular post 146 out of female member openings 126
The approximate centre of the inside upper surface of component 124 is dangled along the longitudinal axis of female component.Preferably, tubular post 146 has
With the inclination or sloping outer surface 148 for introducing geometry, so as to form funnel shaped outer wall.Specifically, tubular post 146
The inside upper surface of outside diameter towards female component 124 gradually increase.Also contemplate other suitable geometric forms for column 146
Shape, such as square, rectangle, hexagon.
Another importance of fluid connection assembly 104 is, male member 128 is generally tubular and with second
Sealing clamp 150, the second sealing clamp 150 is attached to the inner surface of male member, for providing the compression seal of Fluid Sealing.
As the first sealing clamp 138, the second sealing clamp 150 has the second concave side 152 and the second opposite convex side 154.As above
Described, the second sealing clamp 150 has the construction identical with the first sealing clamp 138, and with identical with the first sealing clamp
Mode operate.It is noted, however, that the first and second sealing clamps 138,150 are set with opposite orientation, to prevent fluid
Leaked from fluid connection assembly 104.
More specifically, the first sealing clamp 138 is arranged on the outer upper surface of female component 124 so that the first convex side
142 along the longitudinal axis of female component on fluid flow direction as indicated by arrow c upwardly.On the contrary, the second sealing
Fixture 150 is arranged on the inner surface of male member 128 so that the second convex side 154 along male member longitudinal axis against
Fluid flow direction as indicated by arrow c is downwards.Therefore, when static, the second slit of the second sealing clamp 150 or gap
156 prevent medical fluid from being flowed from the fluid of male member 128, and the first slit of the first sealing clamp 138 or gap 144
Prevent medical fluid from being flowed from the fluid of female component 124.
Also contemplating male member 128 has female member openings 158, which is configured for
Accommodate the insertion of the tubular post 146 of female component 124.Resilient support packing ring 160 with central through hole 162 is arranged on male form structure
Near the upper end of the inner surface of part 128.Since the center through hole 162 of supporting bead 160 is sized to receive female structure
The insertion of the tubular post 146 of part 124, so the internal diameter of through hole is slightly less than the minimum outer diameter of tubular post.Therefore, in female component
When 124 tubular post 146 is gradually inserted in the center through hole 162 of supporting bead 160, the shape between tubular post and supporting bead
Into the interference fit of Fluid Sealing.When tubular post 146 is fully inserted into, it forces slit 156 to be opened, and allows in female
Fluid communication between component 124 and male member 128.
Referring now to Figure 10 and Figure 13, it is preferred that being air connected component 106 is included with female member openings 166
Female component 164, the female member openings 166 are configured for accommodating the insertion for the male member 168 for being air connected component.
An importance for being air connected the female component 164 of component 106 is that hydrophobic filter 118 is arranged on female component 164
Inner surface lower end.For example, hydrophobic filter 118 can by chemical adhesive, solvent bonding, ultrasonic bonding or
Other conventional tightening technologies and be attached to the inner surface of female component 164.
The rigid cylindrical body 170 of male member 168 is wrapped by the flexible elastic body jacket 172 with annular projection 174
Enclose so that when male member 168 is gradually inserted in female member openings 166, annular projection is in sheath and female component
Airtight interference fit is formed between 164.It is preferred, therefore, that the outside diameter of annular projection 174 is less times greater than female member openings
166 internal diameter., can will be any suitable although showing the hollow inside 176 of male member 168 for illustrative purposes
Solid or semi-solid material be individually inserted into the inside of male member or be integrally formed with the inside of male member
To adapt to apply.
Referring now to Fig. 2, Figure 10-12 and Figure 14, figure 14 illustrates the exemplary fluid road of fluid connection assembly 104
Footpath.As described above, it is contemplated to which pumping system is connected to the male member 128 of fluid connection assembly 104.Pumping system will have
Pipe fitting group, the pipe fitting group carry Female Connector 124, it is similar to the Female Connector 124 on aggregating apparatus.When the moon will be carried
When the pipe fitting group of type connector 124 is connected to aggregating apparatus, the tubular post 146 of the inside of Female Connector 124 is by positive opening
Slit 156 in the Male Connector 128 of aggregating apparatus, thus allows medical fluid to lead to from containers for medical use 14 via the second pin
Road 66 and the flowing of the fluid of outlet port 26.
When the male member that the female component 124 of fluid connection assembly 104 is connected to another adjacent aggregating apparatus 74
When 128, negative pressure causes the first sealing clamp 138 of female component to be opened.As a result, the medical fluid from adjacent aggregating apparatus
It will be flowed into via the first pin passage 62 and ingress port 18 in containers for medical use 14, to establish from link or daisy chain
The uninterrupted supply of the medical fluid of the aggregating apparatus of connection.Sealing clamp 138,150 and packing ring 160 are contemplated by flexible bullet
Property material (synthetic resin or plastics, rubber etc.) is made.Also contemplate the other suitable materials for adapting to the application.
The fluid path for contemplating the medical fluid of aggregating apparatus 74 is attached to the group of injection molding as integrated unit
In part.For example, in certain embodiments, the male member 128 of fluid connection assembly 104, which is preferably integratedly laterally attached to, to be collected
The base portion 54 of device 74 so that male member is vertically protruded from base portion.In this configuration, such as Fig. 8 and Fig. 9 similarly institute
Show, when female component and male member 124,128 are connected to each other, realize the reliable connection of the enhancing of the aggregating apparatus of link
Connect, the device for thus preventing from linking is not intended to dismantle.Also contemplate the relative position of female component 124 and male member 128
Be configured to it is opposite with above-mentioned orientation.
Referring now to Figure 10-12, Figure 14 and Figure 15, it is contemplated to which multiple fluids and air path groove 178 are molded into remittance
In the base portion 54 of acquisition means 74, to form at least a portion of the fluid path of medical fluid.In this configuration, ingress port
18 and outlet port 26 be integral in groove 178 as individual unit so that from pin 48 to fluid and be air connected component
104th, 106 fluid and air path seamlessly shift.
More specifically, for fluid path, the female member openings 126 of the female component 124 of fluid connection assembly 104
The first pin passage 62 of pin 48, and the of pin 48 are connected to via the groove 178 being in fluid communication with containers for medical use 14
Two pin passages 66 are connected to the male member opening 158 of the male member 128 of fluid connection assembly using another groove, by
This forms the continuous fluid path from female component 124 to male member 128.
For ventilation path, be air connected component 106 female component 164 female member openings 166 via with it is medical
The groove 178 that container 14 is in fluid communication is connected to the first pin passage 62 of pin 48 so that when the female for being air connected component
When the male member 168 that component is not air connected component blocks, ambient air is sucked into containers for medical use 14.
In certain embodiments, cover and seal the fluid and sky that are limited by groove 178 using protection board 180 (Figure 14)
Gas circuit footpath.Plate 180 is attached to by base by chemical adhesive, solvent bonding, ultrasonic bonding or other conventional tightening technologies
Portion 54.Depending on the shape of groove, the shape of plate 180 is variable, it is contemplated however that other suitable geometries (for example,
Square, rectangle or ellipse) to adapt to apply.
Referring now to Fig. 1, Fig. 2, Figure 14 and Figure 16, another for showing the groove 178 of anti-leakage mechanism 102 is exemplary
Layout, wherein, groove is constructed and arranged to promote double containers for medical use units 12.The correspondence portion of fluid connection assembly 104
Part is represented with reference numeral plus the first two alphabet (i.e. " a " and " b ") label.The importance of the groove structure is, though
So include two single or different fluid connection assembly 104a, 104b in the anti-leakage mechanism 102, but only include
One is air connected component 106 and this is air connected component 106 and is shared by the first and second pins 48,50.
Specifically, the female member openings 166 for being air connected the female component 164 of component 106 are connected via groove 178
To the first pin passage 62 of the first pin 48 and the first pin passage 70 of the second pin 50 so that by being air connected component
The ambient air that receives of female component simultaneously flow into first and second containers for medical use 14,16 in both.Although in order to
The purpose of explanation shows the "T"-shaped ventilation path layout of groove 178, it is contemplated however that other suitable arrangement (such as Y-shapeds
It is laid out with " V " shape) to adapt to apply.
Referring now to Fig. 2, Figure 10 A-10C and Figure 14, it is also contemplated that fluid connection assembly 104 includes first power actuating valve
182 (Figure 10 A), first power actuating valve 182 is connected to the outlet port 26 of aggregating apparatus 74, for being selectively adjusted stream
The orientation fluid flowing of body.In similar construction, fluid connection assembly 104 includes the second power actuating valve 184 (Figure 10 A), should
Second power actuating valve 184 is connected to the ingress port 18 of aggregating apparatus 74, for being selectively adjusted the orientation fluid of fluid
Flowing.
For example, as shown in Figure 10 B, the second power actuating valve 184 be arranged on 110 and first pin 48 of second fluid check-valves it
Between, and it is connected to ingress port 18 so that the stream from connector 114 is controlled by the operation of the second power actuating valve 18
Body flows, to prevent fluid from being leaked from fluid connection assembly 104.Preferably, one way stop peturn valve 186, which is connected to, collects dress
Put it is at least one in 74 ingress port 18 and outlet port 26, to be selectively adjusted the orientation fluid of fluid flowing.
Specifically, in order to activate the second power actuating valve 184 and therefore allow fluid to be flowed in ingress port 18, the
One containers for medical use 14 is urged downwardly the first containers for medical use is transferred to lower position from upper position, as indicated by arrow d
(Figure 10 B).This of first containers for medical use 14 moves down and causes the top 188 of the first containers for medical use 14 to push the actuating of corresponding power
Valve 184, and allow fluid to be flowed from connector 114.On the contrary, when the second power actuating valve 184 is not activated, it is therefore prevented that enter
Fluid flowing in mouth port 18.Also contemplate along the fluid or air stream for being connected to ingress port 18 and outlet port 26
Other suitable positions, to adapt to different applications.
Similarly, the actuating of the first or second power actuating valve 182,184 shown in Figure 10 A is by making aggregating apparatus 74
The first fluid path connector 112 of fluid connection assembly 104 and the second of the fluid connection assembly 104 of another aggregating apparatus
Fluid path connector 114 matchingly or is complementally connected with each other to realize.As discussed above, figure 11 illustrates two phases
The exemplary interconnection of adjacent aggregating apparatus 74a, 74b.
At least one pin in pin 48,50 is also contemplated by the bag (shown in broken lines in fig. 14) of pin sheath 190
Enclose, which is configured for the ingress port 18 of aggregating apparatus 74 and outlet port 26 connecting into fluid company
It is logical.For example, in initial position, pin sheath 190 surrounds simultaneously and securely the first pin passage 62 of the first pin 48
With the second pin passage 66, thus allow air flow between the ingress port 18 of aggregating apparatus 74 and outlet port 26 or
Fluid flows.
But as shown in Figure 10 B, pin sheath 190 can be pierced and compress when container 14 is pressed down.As above institute
State, when the first containers for medical use 14 is transferred to lower position from upper position as shown by arrow D, pin sheath 190 is also by container
Upper position of 14 top 188 shown in Figure 14 is pushed down on to the lower position shown in Figure 10 B.Pass through this of container 14
Kind movement, pin sheath 190 is destroyed, and realizes the flowing of the fluid between ingress port and outlet port 18,26.
Referring now to Figure 10 C and Figure 14, fluid connection assembly 104 includes pin connector 192 and access dome valve 194.
Preferably, pin connector 192 is connected to the ingress port 18 of aggregating apparatus 74, and entrance dome valve 194 is connected to remittance
The outlet port 26 of acquisition means.As described above, access dome valve 194 has and the snap-fitted locking mechanism 130 shown in Figure 14
The similar construction of the second sealing clamp 150.In such configuration, access dome valve 194 has opening or through hole 162, this is opened
Mouth or through hole 162 are configured for accommodating the insertion of pin connector 192 with complementary relationship.
Referring now to Fig. 1, Fig. 8 and Figure 17 A- Figure 17 D, aggregating apparatus 74 includes cap remover 198, the cap remover 198
At least one aggregating apparatus for being attached in aggregating apparatus and it is configured for removing the top cap 42 of corresponding container.
In preferred embodiment, cap remover 198 includes the center cavity 200 with head zone 202 and tail region 204, wherein, institute
Head zone and tail region is stated preferably inwardly to set with the reciprocal cavity that is oriented around.In use, cap remover
198 head zone 202 engages or catches top cap 42, and the point for leaning around caudad region 204 pivots, and top cap is opened,
(Figure 17 C) as shown by arrow E.Although for illustrative purposes cap remover 198 is shown as substantially justifying in Figure 17 A-17C
The shape of shape or ellipse, it is contemplated however that other suitable shapes or designs, such as polygon or irregular shape, to adapt to
Using.
As shown in figure 17d, it is also contemplated that base portion of the head zone 202 of cap remover 198 preferably with aggregating apparatus 10
54 are integrally formed.In such configuration, the head zone 202 of cap remover 198 is fixedly attached to the base of aggregating apparatus 10
Portion 54, and there is no tail region 204.During use, the top cap 42 of containers for medical use unit 12 close to aggregating apparatus 10 be inverted
Position positions so that the head zone 202 at base portion 54 can be tightly engaged into or coordinate with the top cap of container.Next, container
14 pivot relative to top cap 42 around the point opposite with head zone 202 so that container is pulled open with by top cap from aggregating apparatus 10
Open, as shown in arrow E'.
Referring now to Fig. 1, Figure 10 and Figure 18, it is contemplated to which in certain embodiments, fluid connection assembly 104 includes hydrophobic mistake
It is at least one in filter 206 and hydrophilic filter 208.In certain embodiments, hydrophobic filter 206, which is connected to, collects dress
10 ingress port 18 is put, to be selectively adjusted the flowing of the orientation air/fluid of aggregating apparatus.On the contrary, hydrophilic filter
Device 208 is connected to the outlet port 26 of aggregating apparatus 10, to be selectively adjusted the orientation fluid of aggregating apparatus and air
Flowing.
In the representative configuration for being constructed and arranged to Figure 18 for promoting double containers for medical use units 12, the first hydrophobic mistake
Filter 206' is connected to the first entrance port for the first containers for medical use 14 for being configured for the first medical fluid of storage
18'.Similarly, the second hydrophobic filter 206 " is connected to the second medical appearance for being configured for the second medical fluid of storage
The second entrance port 18 " of device 16.It is therefore advantageous that the first hydrophobic filter 206' and the second hydrophobic filter 206 " are permitted
Perhaps air discharge is leaked without any undesirable fluid from ingress port 18', 18 ".
In order to optionally control the orientation fluid of the first or second medical fluid to flow, hydrophilic filter 208 is connected
To the first outlet port 26' of the first containers for medical use 14 and the second outlet port 26 " of the second containers for medical use 16.In this construction
In, hydrophilic filter 208 advantageouslys allow for air to discharge, until it is soaked by the first or second medical fluid, hereafter hydrophilic mistake
Filter only allows medical fluid to be advanced through fluid path connector 112.
Only as an example, when the first containers for medical use 14 empties fluid, hydrophilic filter 208 prevents air from passing through hydrophilic mistake
Filter and it is infused into patient's body.This air bound is also prevented from any fluid and flows and cause pump to send alarm, should
Alarm sends signal with running fix valve 216 to be opened to the flow path of the second containers for medical use 16 to patient/nursing staff.Connect
, recover pump operating, to be transfused the inclusion of the second containers for medical use 16.If hydrophilic filter 208 is also mounted at outlet port
In 216 ", then when containers for medical use 16 empties, hydrophilic filter prevents air by filter and is infused into patient body.
This air bound prevents any fluid to flow, and causes pump to send alarm, which sends the to patient/nursing staff
The signal that two kinds of medical fluid injections are completed.Also contemplate hydrophobic filter 206 and other suitable cloth of hydrophilic filter 208
Put to adapt to different applications.
Referring now to Fig. 1, Fig. 6, Fig. 7, Figure 10, Figure 11 and Figure 19, it is contemplated to which tray component 210 is included with arranged in series chain
At least one aggregating apparatus 74 of the invention connect, so that aggregating apparatus is attached to tray component in a manner of being in fluid communication
In.In Figure 19, although a aggregating apparatus 74 in four (4) is incorporated into tray component 210, it is contemplated however that any quantity or
The aggregating apparatus of embodiment is to adapt to apply.Flowing lid 212 with least one flow path or path 214 is attached to support
Disk component 210 is to promote the fluid communication between aggregating apparatus 74.Preferably, the first flow passage 214' is set to be used to connect
First containers for medical use 14, and set the second separated flow passage 214 " be used for connect the second containers for medical use 16.In the example
In, tray component 210 includes multiple aggregating apparatus 74 that fluid flow communication is attached in tray component.In addition, tray component 210
Including two sseparated pipelines or path 214', 214 ", described two separated pipelines or passage 214', 214 " are configured to use
In two kinds of single fluids are transported to outlet port 52 from the first and second containers for medical use 14,16.With Fig. 1, Fig. 6 and Figure 11 institute
The component that the aggregating apparatus 10 shown shares is presented with like reference characters.
Preferred trays component 210 includes normal valve 216, which is configured for selectively allowing for or adjusts
Save the fluid path of at least one containers for medical use in the first and second containers for medical use 14,16.For example, normal valve 216 is
With the manual switch or plug valve for reversing valve, it is configured for selectively allowing for and prevents to come from first and/or the
The fluid flowing of two containers for medical use 14,16.Also contemplate when pipe fitting group 28 is separated from tray component 210, normal valve 216 provides
Valve accesses, to prevent fluid from flowing.In a preferred embodiment, lug cap 218 is set to protect pin sheath 190 and pin
48、50.As an example, in Figure 19, it is used for a path to the fluid path connector 112 in another path at point 108
Valve 216 is positioned to replace.Normal valve 216 is contemplated with luer lock connector and can axial-rotation so that user is controlled
Which kind of fluid is conveyed to user by system.
Referring now to Fig. 1, Fig. 4, Fig. 7-Fig. 9 and Figure 20, it is preferred that aggregating apparatus 74,86a are constructed and arranged to can
Stack, linkable modular unit.It is presented with like reference characters with aggregating apparatus 10,74, the 86a component shared.Such as
It is similarly shown in Fig. 4 and Fig. 7-Fig. 9, it is contemplated to which that aggregating apparatus 86a includes the first wing 88a and the second wing 90a, first wing
88a is configured for accommodating outlet port 26a, and second wing 90a is configured for accommodating ingress port 18a.
The first and second medical fluids are not intended to leak in order to prevent, as shown in figure 20, for example, the first hydrophobic filter
118' is arranged at ingress port 18a and is connected to the first pin 48, and the second hydrophobic filter 118 " is arranged on second
At wing 90a and it is connected to the second minute hand 50.It is different to be adapted to contemplate hydrophobic filter 118', 118 " other suitably-arrangeds
Using.
As shown in figure 20, it is contemplated to aggregating apparatus 86a includes having at least one Moveable path or path 214',
214 " flowing lid 212, to promote fluid to be flowed from corresponding pin 48,50.Each flow path 214', 214 ", which use, to be divided
Every component 220 according to 62,66,70,72 bifurcated of pin passage of corresponding pin 48,50 or separation.Also contemplate setting at least
One protection board or lid 222 are with the fluid or air path or path of the sealing exposure associated with aggregating apparatus 86a.In addition,
At least one cap component 224 is set removably to block the fluid associated with aggregating apparatus 86a or air path or path.
Although the specific embodiment of the aggregating apparatus of the present invention already described herein, those skilled in the art will
It will be appreciated that can be in the case of the broader aspect without departing from the disclosure and as set forth in the appended claims to it
Make a change and change.
Claims (56)
1. one kind is used for the aggregating apparatus [10] for collecting the fluid from container unit [12], the container unit [12] has extremely
A few container [14,16], the aggregating apparatus includes：
Ingress port [18], the ingress port [18] have at least one access road [22,24], the ingress port [18]
It is configured for receiving fluid or ambient air；
Outlet port [26], the outlet port [26] have at least one exit passageway [32,34], the outlet port [26]
It is configured for delivering the fluid to annex, the ingress port and the outlet port are arranged on the aggregating apparatus
On；
Cavity [40], the cavity [40] are configured for the insertion of holding said container unit [12], are come to collect
The fluid of at least one container [14,16]；And
At least one pin [48,50], at least one pin [48,50] are arranged in the cavity, and it is described extremely
A few pin [48,50] is configured for when the container unit is transferred to lower position from upper position described in puncture
The plug [44,46] of at least one container.
2. aggregating apparatus according to claim 1, wherein, the ingress port [18] is connected to via corresponding pipe [64]
The outlet port [26] being in fluid communication with least one pin [48,50].
3. aggregating apparatus according to claim 1 or 2, wherein, at least one pin [48,50] has the first pin
Passage [62,70], the first pin passage [62,70] are connected at least one access road [22,24].
4. the aggregating apparatus according to any one of preceding claims, wherein, at least one pin [48,50] tool
Have the second pin passage [66,72], the second pin passage [66,72] be connected at least one exit passageway [32,
34]。
5. the aggregating apparatus according to any one of preceding claims, wherein, the ingress port and the port of export
At least one in mouthful [18,26] has protection cap [38], and the protection cap [38] is for protecting the corresponding access road
With exit passageway [22,24；32nd, 34] from pollution.
6. the aggregating apparatus according to any one of preceding claims, wherein, at least one pin [48,50] from
The inner surface [52] of the base portion [54] of the aggregating apparatus [10] vertically protrudes.
7. the aggregating apparatus according to any one of preceding claims, wherein, the aggregating apparatus [10] has locking
Mechanism [58], the locking mechanism [58] are configured for during use being firmly held in the container unit [12]
In the cavity [40].
8. aggregating apparatus according to claim 7, wherein, the locking mechanism [58] is arranged on the cavity [40]
On inner wall [60].
9. the aggregating apparatus according to any one of preceding claims, wherein, the cavity [40] is configured for
The insertion of holding said container unit [12], to collect the fluid for coming from single container [14,16].
10. the aggregating apparatus according to any one of preceding claims, wherein, at least one container [14,16]
Storage fluid is configured to, and the container unit [12] is attached to the aggregating apparatus [10].
11. the aggregating apparatus according to any one of preceding claims, wherein, the aggregating apparatus [10] includes locking
Mechanism [76], the lockable mechanism [76] are configured for preventing the container unit [12] from being transferred to from the upper position
The lower position.
12. the aggregating apparatus according to any one of preceding claims, wherein, the container unit [12] includes locking
Sell [76], the lock pin [76] is inserted into the slot [78] being arranged on the body [80] of the container unit [12]
In.
13. the aggregating apparatus according to any one of preceding claims, wherein, at the top of the container unit [12]
On be provided with press strip [82], to by push down on the press strip make the container unit [12] from the upper position turn
Move on to the lower position.
14. the aggregating apparatus according to any one of preceding claims, wherein, the aggregating apparatus [10] can be with mutual
Benefit relation is connected with another aggregating apparatus and is linked, to establish the fluid of the aggregating apparatus [74a, 74b, 74c] from link
Uninterrupted supply.
15. the aggregating apparatus according to any one of preceding claims, wherein, the first aggregating apparatus [74a] it is described
Ingress port is configured to be inserted into the outlet port [26b] of the second aggregating apparatus [74b] with complementary relationship.
16. the aggregating apparatus according to any one of preceding claims, wherein, the first aggregating apparatus [74a] and second
Aggregating apparatus [74b] is linked together relative to the longitudinal axis of each aggregating apparatus with complementary relationship series connection.
17. the aggregating apparatus according to any one of preceding claims, wherein, the aggregating apparatus [10] is moved including cap
Except device [198], the cap remover [198] is attached at least one container [14,16] and is configured for moving
Except the top cap [42] of at least one container.
18. the aggregating apparatus according to any one of preceding claims, further includes anti-leakage mechanism [102], described anti-
Leakage mechanism [102] has fluid connection assembly [104] and is air connected component [106], fluid connection assembly [104] quilt
It is configured to be used to control the fluid path in the aggregating apparatus [10], the component [106] that is air connected is configured for
Control the ventilation path in the aggregating apparatus.
19. aggregating apparatus according to claim 18, wherein, the component [106] that is air connected connects including air path
Device [116] is connect, the air path connector [116] is connected to the aggregating apparatus [10] via hydrophobic filter [118]
The ingress port [18].
20. aggregating apparatus according to claim 18, wherein, the fluid connection assembly [104] is stopped including first fluid
Valve [108] is returned, the first fluid check-valves [108] is connected to the outlet port [26] of the aggregating apparatus [10],
To be selectively adjusted the flowing of the orientation fluid of fluid.
21. aggregating apparatus according to claim 18, wherein, the fluid connection assembly [104] is stopped including second fluid
Valve [110] is returned, the second fluid check-valves [110] is connected to the ingress port [18] of the aggregating apparatus [10],
To be selectively adjusted the flowing of the orientation fluid of fluid.
22. aggregating apparatus according to claim 20, wherein, the first fluid check-valves [108] has first fluid
Path connector [112], the first fluid path connector [112] are configured for being releasably attached in complementary fashion
To the second check-valve [110] of another aggregating apparatus.
23. aggregating apparatus according to claim 21, wherein, the second fluid check-valves [110] has second fluid
Path connector [114], the second fluid path connector [114] are configured for being releasably attached in complementary fashion
To the first fluid check-valves [108] of another aggregating apparatus.
24. aggregating apparatus according to claim 20, wherein, the first fluid check-valves [108] and the second
The Opening pressure of body check-valves [110] is in 3 pound per square inches into the scope of 5 pound per square inches.
25. aggregating apparatus according to claim 18, wherein, the component [106] that is air connected includes having blind chamber
[122] air path connector [120], the air path connector [120] are configured for releasably connecting in complementary fashion
It is connected to the air path connector [116] of another aggregating apparatus.
26. aggregating apparatus according to claim 18, wherein, the fluid connection assembly [104] includes having first the moon
First female component [124] of type member openings [126], the first female member openings [126] are configured for accommodating
The insertion of the first male member [128] of the fluid connection assembly.
27. aggregating apparatus according to claim 26, wherein, the fluid connection assembly [104] includes component locking machine
Structure [130], the component locking mechanism [130] are configured for the first female component of the fluid connection assembly
It is releasably attached with first male member.
28. aggregating apparatus according to claim 26, wherein, the first female component has the first sealing clamp
[138], first sealing clamp [138] is configured for preventing the orientation fluid of fluid from flowing.
29. aggregating apparatus according to claim 26, wherein, first male member has the second sealing clamp
[150], second sealing clamp [150] is configured for preventing the orientation fluid of fluid from flowing.
30. aggregating apparatus according to claim 26, wherein, the first female component has from the first female structure
The column [146] of the inside upper surface pendency of part [124].
31. aggregating apparatus according to claim 30, wherein, first male member has supporting bead [160], institute
Stating supporting bead [160] has center through hole [162], and the center through hole [162] is sized to receive described first
The insertion of the column of female component.
32. aggregating apparatus according to claim 18, wherein, the component that is air connected includes having the second female component
Second female component [164] of opening [166], the second female member openings [166] are configured for accommodating the sky
The insertion of the second male member [168] of gas connection component.
33. aggregating apparatus according to claim 32, wherein, hydrophobic filter [118] is arranged on second female
In the second female member openings of component.
34. aggregating apparatus according to claim 32, wherein, second male member is configured in the shield
Airtight interference fit is formed between set and the second female component.
35. aggregating apparatus according to claim 32, wherein, second male member is by with annular projection [174]
Sheath [172] surround.
36. aggregating apparatus according to claim 18, wherein, multiple fluids and air are provided with the aggregating apparatus
Path tube [64], the path tube are constructed and arranged to the ventilation path for making the aggregating apparatus and the fluid
At least one in path is in fluid communication with each other.
37. aggregating apparatus according to claim 36, wherein, it is described to be air connected component [106] while be connected to described
At least two containers of aggregating apparatus and shared by least two container.
38. aggregating apparatus according to claim 18, wherein, the fluid connection assembly [104] activates including the first power
Valve [182], the first power actuating valve [182] is connected to the outlet port of the aggregating apparatus, to optionally
Adjust the orientation fluid flowing of fluid.
39. aggregating apparatus according to claim 18, wherein, the fluid connection assembly [104] activates including the second power
Valve [184], the second power actuating valve [184] is connected to the ingress port of the aggregating apparatus, to optionally
Adjust the orientation fluid flowing of fluid.
40. aggregating apparatus according to claim 18, wherein, the fluid connection assembly [104] includes one way stop peturn valve
[186], the one way stop peturn valve [186] is connected to the ingress port of the aggregating apparatus, to be selectively adjusted
The orientation fluid flowing of fluid.
41. aggregating apparatus according to claim 18, wherein, at least one pin is surrounded by pin sheath [190],
The pin sheath [190] is configured for connecting the ingress port and the institute of the aggregating apparatus with fluid communication
State outlet port.
42. aggregating apparatus according to claim 18, wherein, the fluid connection assembly includes pin connector [192]
With access dome valve [194].
43. aggregating apparatus according to claim 42, wherein, the access dome valve [194], which has, to be configured for
The opening of the insertion of the pin connector [192] is accommodated with complementary relationship.
44. aggregating apparatus according to claim 18, wherein, the fluid connection assembly include hydrophobic filter [118,
206] it is at least one and in hydrophilic filter [208].
45. aggregating apparatus according to claim 44, wherein, the hydrophobic filter [118,206] is connected to described
The ingress port of aggregating apparatus, to be selectively adjusted the orientation air flow of the aggregating apparatus.
46. aggregating apparatus according to claim 44, wherein, the hydrophilic filter [208] is connected to described collect
The outlet port of device, to be selectively adjusted the flowing of the orientation fluid of the aggregating apparatus.
47. the aggregating apparatus according to any one of preceding claims, further includes tray component [210], the pallet
Component [210] includes at least one aggregating apparatus being attached to fluid communication in the tray component.
48. aggregating apparatus according to claim 47, wherein, the tray component [210] includes flowing lid [212], institute
Stating flowing lid [212] has at least one flow passage and is attached to the tray component for promoting to be in fluid communication.
49. aggregating apparatus according to claim 47, wherein, the tray component [210] includes normal valve [216], institute
Normal valve [216] is stated to be configured for being selectively adjusted the flow path from least one container.
50. the aggregating apparatus according to any one of preceding claims, wherein, at least one hydrophobic filter [118,
206] it is connected at least one in the ingress port and the outlet port.
51. the aggregating apparatus according to any one of preceding claims, wherein, at least one hydrophilic filter [208]
It is connected at least one in the ingress port and the outlet port.
52. the aggregating apparatus according to any one of preceding claims, further includes tray component [210], the pallet
Component [210] includes the multiple aggregating apparatus being attached to fluid communication in the tray component.
53. aggregating apparatus according to claim 52, wherein, the tray component [210] includes two independent pipes
[64], described two independent pipes [64] are configured for two kinds of independent fluids being transported to from the multiple aggregating apparatus
The outlet port.
54. a kind of aggregating apparatus [10] for being used to collect medical fluid, including：
Container unit [12], the container unit [12] have at least one container [14,16] for being configured to storage fluid, institute
State container unit and be attached to the aggregating apparatus；
Ingress port [18], the ingress port [18] have at least one access road [22,24], the ingress port [18]
It is configured for receiving fluid or ambient air；
Outlet port [26], the outlet port [26] have at least one exit passageway [32,34], the outlet port [26]
It is configured for delivering the fluid to annex, the ingress port and the outlet port are arranged on the aggregating apparatus
On；
Cavity [40], the cavity [40] are configured for the insertion of holding said container unit [12], are come to collect
The fluid of at least one container [14,16]；And
At least one pin [48,50], at least one pin [48,50] are arranged in the cavity, and it is described extremely
A few pin [48,50] is configured for when the container unit is transferred to lower position from upper position described in puncture
The plug [44,46] of at least one container,
Wherein, the aggregating apparatus [10] can be complementary with arranged in series and another aggregating apparatus relative to each aggregating apparatus
Ground links, to establish the uninterrupted supply of the fluid of the aggregating apparatus from link.
55. aggregating apparatus according to claim 54, wherein, the aggregating apparatus [10] includes first wing [88] and second
The wing [90], first wing [88] are configured for accommodating the outlet port, and second wing [90] is configured for
Accommodate the ingress port.
56. the aggregating apparatus according to claim 54 or 55, wherein, second wing [90] is relative to first wing
[88] vertically shift.
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| US201562182099P | 2015-06-19 | 2015-06-19 | |
| US62/182,099 | 2015-06-19 | ||
| PCT/US2016/038136 WO2016205687A1 (en) | 2015-06-19 | 2016-06-17 | Pooling device for single or multiple containers |
Publications (1)
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|---|---|
| CN108040465A true CN108040465A (en) | 2018-05-15 |
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| CN201680035766.0A Pending CN108040465A (en) | 2015-06-19 | 2016-06-17 | Aggregating apparatus for single or multiple containers |
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| US (3) | US11219578B2 (en) |
| EP (3) | EP4434555A2 (en) |
| JP (4) | JP6993965B2 (en) |
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| CO (1) | CO2017012908A2 (en) |
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| MY (1) | MY184064A (en) |
| PL (1) | PL3310321T3 (en) |
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| RU (1) | RU2737287C2 (en) |
| SI (1) | SI3310321T1 (en) |
| TR (1) | TR201910248T4 (en) |
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