CN105662532A - Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same - Google Patents
Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same Download PDFInfo
- Publication number
- CN105662532A CN105662532A CN201610006988.1A CN201610006988A CN105662532A CN 105662532 A CN105662532 A CN 105662532A CN 201610006988 A CN201610006988 A CN 201610006988A CN 105662532 A CN105662532 A CN 105662532A
- Authority
- CN
- China
- Prior art keywords
- taking
- thrombus
- semi
- bolt device
- embolectomy device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 208000007536 Thrombosis Diseases 0.000 title claims abstract description 69
- 210000004204 blood vessel Anatomy 0.000 title abstract description 30
- 238000013156 embolectomy Methods 0.000 title abstract 13
- 239000003146 anticoagulant agent Substances 0.000 claims description 10
- 239000008280 blood Substances 0.000 claims description 10
- 210000004369 blood Anatomy 0.000 claims description 10
- 238000011161 development Methods 0.000 claims description 10
- 230000010102 embolization Effects 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 7
- 229940030225 antihemorrhagics Drugs 0.000 claims description 6
- 230000000025 haemostatic effect Effects 0.000 claims description 6
- 238000011084 recovery Methods 0.000 claims description 6
- 230000001225 therapeutic effect Effects 0.000 claims description 5
- 229940127219 anticoagulant drug Drugs 0.000 claims description 4
- 239000012781 shape memory material Substances 0.000 claims description 4
- 229940127218 antiplatelet drug Drugs 0.000 claims description 3
- 230000008859 change Effects 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- 230000000007 visual effect Effects 0.000 claims description 3
- 238000003466 welding Methods 0.000 claims description 3
- 208000005189 Embolism Diseases 0.000 abstract description 14
- 230000006378 damage Effects 0.000 abstract description 4
- 230000000740 bleeding effect Effects 0.000 abstract 2
- 208000001435 Thromboembolism Diseases 0.000 description 10
- 238000000034 method Methods 0.000 description 10
- 230000008901 benefit Effects 0.000 description 8
- 238000007917 intracranial administration Methods 0.000 description 8
- 230000002537 thrombolytic effect Effects 0.000 description 8
- 230000008569 process Effects 0.000 description 7
- 230000033001 locomotion Effects 0.000 description 5
- 238000013461 design Methods 0.000 description 4
- 230000017531 blood circulation Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 230000002093 peripheral effect Effects 0.000 description 3
- 230000009424 thromboembolic effect Effects 0.000 description 3
- 102000003978 Tissue Plasminogen Activator Human genes 0.000 description 2
- 108090000373 Tissue Plasminogen Activator Proteins 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 206010008118 cerebral infarction Diseases 0.000 description 2
- 208000026106 cerebrovascular disease Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 238000013151 thrombectomy Methods 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 201000001429 Intracranial Thrombosis Diseases 0.000 description 1
- 208000032382 Ischaemic stroke Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 102000003990 Urokinase-type plasminogen activator Human genes 0.000 description 1
- 108090000435 Urokinase-type plasminogen activator Proteins 0.000 description 1
- 208000024248 Vascular System injury Diseases 0.000 description 1
- 208000012339 Vascular injury Diseases 0.000 description 1
- 229910001080 W alloy Inorganic materials 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 230000036783 anaphylactic response Effects 0.000 description 1
- 208000003455 anaphylaxis Diseases 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000002583 angiography Methods 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000008602 contraction Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 229910003460 diamond Inorganic materials 0.000 description 1
- 239000010432 diamond Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000003527 fibrinolytic agent Substances 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000001361 intraarterial administration Methods 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 238000010253 intravenous injection Methods 0.000 description 1
- 230000000302 ischemic effect Effects 0.000 description 1
- 230000006386 memory function Effects 0.000 description 1
- 210000003657 middle cerebral artery Anatomy 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- -1 platinoiridita Chemical compound 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- ZONODCCBXBRQEZ-UHFFFAOYSA-N platinum tungsten Chemical compound [W].[Pt] ZONODCCBXBRQEZ-UHFFFAOYSA-N 0.000 description 1
- 229950000845 politef Drugs 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000250 revascularization Effects 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 229960005356 urokinase Drugs 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 238000004804 winding Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
- A61B2017/22042—Details of the tip of the guide wire
- A61B2017/22044—Details of the tip of the guide wire with a pointed tip
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
- A61B2017/2215—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having an open distal end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1052—Balloon catheters with special features or adapted for special applications for temporarily occluding a vessel for isolating a sector
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
The invention relates to a blood-vessel embolectomy device with a semi-closed structure and a thrombus treating apparatus with the same. The blood-vessel embolectomy device comprises an embolectomy device body, a developing loop located at the near end of the embolectomy device body and developing rings located at the far end of the embolectomy device body. The embolectomy device body is of a web-tubular or cage-shaped structure composed of a plurality of connected unit grids; the near end of the embolectomy device body is of the closed conical structure; a longitudinal gap is formed in the side face of the far end of the embolectomy device body. The thrombus treating apparatus comprises the blood-vessel embolectomy device with the semi-closed structure, a protecting sheath tube, a conveying wire, a micro guide tube, a guiding guide tube and a rotating bleeding stopping valve. The micro guide tube is pushed to a thrombus embolism in the guiding guide tube along the guiding guide tube, the protecting sheath tube is communicated with the micro guide tube through the rotating bleeding stopping valve, and the embolectomy device body is placed in the protecting sheath tube, pushed into the micro guide tube through the conveying wire and pushed to the thrombus embolism. According to the blood-vessel embolectomy device with the semi-closed structure and the thrombus treating apparatus, flexibility is good, the embolectomy device body can pass through the bent blood vessel or reach the blood vessel with the thin far end, and harm to the blood vessel wall is small.
Description
Technical field
The present invention relates to a kind of taking thrombus device with semi-closed structure and thrombus treating apparatus thereof, specifically, particularly to a kind of medical apparatus and instruments getting involved blood vessel, for when acute ischemic stroke occurs, eliminating mechanically and be blocked in endovascular thrombosis to reach the Therapeutic Method of instant recovery blood flow, what be particularly suited for intracranial vessel takes bolt.
Background technology
Cerebral infarction is once occur, it is necessary within the shortest time, (effective time window) makes revascularization. At present, the Therapeutic Method of Intracranial thrombus mainly has two kinds: medicine thrombolytic and machinery take bolt.
Medicine thrombolytic is with thrombus by intravenous injection rt-PA (tissue-type plasminogen activator) or urokinase, it is possible to by intra-arterial contact thrombolysis, antiplatelet aggregation and anticoagulant treatment etc. Although thromboembolism treatment has been shown to improve preferably neurological outcome, but, according to US National sacred disease and apoplexy institute (TheNationalInstituteNeurologicalDisordersandStrokert-PAS trokeStudyGroup, NINDS) research is thought, intravenous thrombolysis should carry out within falling ill 3 hours, Arterial thrombolysis time window should within 6 hours, and the patient that so short thrombolytic time window causes only 4.5%-6.3% can accept thromboembolism treatment; Secondly, thromboembolism treatment is suitable only for the thrombosis of small volume, and the therapeutic effect of large volume thromboembolism is unsatisfactory; And, thrombolytic drug is had anaphylaxis by some patients, is not suitable for thromboembolism treatment.
In order to solve the problem of said medicine thrombolytic, for exceeding thrombolytic time window and not tolerating the patient of thromboembolism treatment, adopt machinery to take bolt and remove the thrombosis of blocking. In the prior art, it has been disclosed that machinery as described below takes pin device:
In the patent of invention that the patent No. is CN104000635A " take bolt device and take pin device " that China announces, have and multiple stretch into the cancellated intraluminal interior female rod with three-D profile, tube chamber is fixed at its two ends, in removal process after catching thrombosis, it is possible to by interior female rod fix blood bolt.
The patent of invention " for removing the device of thrombosis from blood vessel " that the patent No. disclosed in China is CN101340849A, by a caged or tubular structure, one distal member with the fiber extended radially out is taken in wherein, and safely eliminate thrombosis from Ink vessel transfusing under the help of fiber.
In the patent of invention " Intravascular Thrombus and embolus resectoscope " that the patent No. disclosed in China is CN101396295A; there is the thrombectomy device of a thrombectomby spring and the basket in contraction or release conditions; basket is positioned at the far-end of thrombectomy device; arrest thrombosis by the winding of thrombectomby spring, and take out to protect the far-end of blood vessel with basket together with thrombosis fragment by taking the clot of generation in bolt process.
In the patent of invention that the patent No. is CN102316809A " endovascular thrombosis grabber " that China announces, having the line main body haunted freely and be located at the thrombosis capture portion of its front end, the motion of the elastica circle body by being erected between fixed part and movable part removes, to catch, the thrombosis being attached to blood vessel wall.
In the patent of invention " device for removal of thromboses " that the patent No. disclosed in China is CN101035474A, there is the guide wire that a far-end is equipped with the fiber component of an orthohormbic structure, from body cavity and blood vessel, take out foreign body and thrombosis by the motion before and after it.
In the patent of invention that the patent No. is CN102014772A " method and apparatus for restoration of blood flow " that China announces, have a self expandable taper overlay structure by the cancellated parts of interconnective line or filament or pillar, by microtubular with push after wire is introduced into inaccessible blood vessel self expandable to recover blood flow.
In the patent of invention " for treating the system and method for cerebral infarction " that the patent No. disclosed in China is CN101027004A, there is guiding and occlusion catheter, conveying and draw catheter, lift suction pump, thromboembolic receiver and thromboembolic separator, lift suction pump passes through draw catheter by Biochemical analyzer to thromboembolic receiver, thus withdrawing from external.
In the utility model that the patent No. is ZL200620164685.4 " taking bolt device " of China's bulletin, there is the umbrella of the three-jaw short by two length one of elastic memory function, with periphery have net formed a circular configuration take pin device, by drawing push-pull bar to make three-jaw close up outward, thrombosis pocket is recovered in trocar sheath in umbrella portion, thrombosis is taken out.
In the patent of invention that the patent No. is US7931659B2 " SystemandMethodforTreatingIschemicStroke " of U.S. Publication, there is a receptor being surrounded into hollow tubular by many filaments being fixed on an elongated extension tube end, by extension tube, receptor is placed in blood vessel embolism position, and thrombosis taken in the intracavity of receptor hollow and takes out external.
In the patent of invention that the patent No. is US2006/0047286A1 " ClotRetrieverDevice " of U.S. Publication, there is one and be fixed on the expansible of pusher end and the recovery basket shunk, it has a tinsel that can pass through to be fixed on basket end control the uncovered in order to be caught in basket by thrombosis of opening and closing.
In the patent of invention that the patent No. is US2002/0049452A1 " ClotRetrieverDevice " of U.S. Publication, have one or more be fixed on slender conduit can in compression element movable have a shape memory take latch, after being transported to thromboembolism position by slender conduit, take in latch is flared out thrombosis is caught and is wrapped in.
In the patent of invention that the patent No. is US2009/0240238A1 " ClotRetrievalMechanism " of U.S. Publication, have one be fixed on a slender axles end can the snare of self-expanding and an attached to it folding sack being made up of flexible non-porous material, by slender axles, device is placed in thromboembolism position along internal passage, opens sack by thrombosis bag in the inner.
Various machineries described above take pin device, all there is open defect: when thrombosis cannot be looked at straight, the catching device of basket or web form tends not to entangle blood clot and causes taking bolt failure, and its volume is often excessive, cannot use in the cerebral arterieies such as thinner middle cerebral artery M1, M2 section of blood vessel diameter, when catching recovery after thrombosis, thrombosis is fixed insecure, it is easy to come off; Although although the pin device that takes having solves the problem of thrombus breaks loose, but its structure is complicated, the interior female rod structure for fixing thrombosis of increase makes the compliance taking pin device overall greatly reduce, so as to tortuous intracranial vessel can not be passed through.
On the other hand, although it is safe that the mode of existing negative pressure absorbing takes bolt, but only that relatively soft thromboembolism is effective by drawing removal; In order to strengthen drawing effect, adopt rotating blade or resectoscope fragmentation thrombosis, although this rotating blade feature improves the effect of this aspiration technique, but considerably increased the risk that blood vessel wall is caused damage; Although laser and ultrasound wave are cleaning and the effective energy, but such as misoperation, very easily peripheral vessels are caused damage, and energy is too low then invalid, too high then injured blood vessel, therefore it is difficult to determine that giving how high-octane laser intensity can be only achieved optimum curative effect.
Accordingly, it would be desirable to prior art is further improved, it is desirable to the intracranial vessel designing a kind of improvement takes bolt device, one, and volume should be sufficiently small, compliance should be enough good, so that device can enter the distal vessels that intracranial is thinner; Its two, capture rate is high, and thrombosis is grip good, fixation in taking bolt removal process, difficult drop-off; Its three, radially support force is little, and blood vessel wall and Peripheral Vascular Injuries is little.
Summary of the invention
The technical problem to be solved is in that, a kind of taking thrombus device with semi-closed structure and thrombus treating apparatus thereof are provided, take bolt device and be provided with half-open semi-enclosed structure, not only there is good pulling property but also there is overall compliance better, take during bolt the chucking power of thrombosis is sufficiently large, take thrombosis in bolt process and do not slip; Compliance is good, takes bolt device and can pass through curved blood vessel or arrive the blood vessel that far-end is thinner; Radially support force is little, takes in bolt process and causes damage to be preferably minimized blood vessel wall and peripheral vessels.
The present invention is realized in, a kind of taking thrombus device with semi-closed structure is provided, can be used for intracranial, cervical region, including taking bolt device, it is positioned at the developing ring taking bolt device near-end and is positioned at the development circle taking bolt device far-end, described take webmaster shape or the cage structure that bolt device includes being made up of multiple unit grids being coupled to each other, each described unit grid by interconnective muscle around forming, this webmaster shape or cage structure can be collapsed folding under pressure and have self-expanding recovery capability in a free state, and, this webmaster shape or collapsing of cage structure fold and expand and can mutually change without difficulty, the proximal end taking bolt device described under self-expanding state is arranged to pyramidal structure, its proximate expand gradually, the described near-end pyramidal structure taking bolt device is to close, and is provided with axial clearance on the side of its far-end. this device can be used for human vas, and other adapts to position.
Further, described in take bolt device there is oblong shape or oblong shape under self-expanding state, its length range is between 5 millimeters to 60 millimeters, and its diameter range is between 2 millimeters to 6 millimeters.
Further, the ratio of the length of described unit grid and height is more than 1 and less than 2.
Further, the surface-coated taking bolt device described in has the coating containing anticoagulant or antiplatelet drug.
Further, described developing ring and development circle all by can be visual under X ray material make.
Further, described developing ring and development circle are connected with taking bolt device by modes such as welding or crimp or be cementing.
Further, take bolt device described in be made up of shape-memory material.
The invention also discloses a kind of thrombus treating apparatus; employ the aforesaid taking thrombus device with semi-closed structure; this therapeutic instrument also includes protection sheath pipe, conveying silk, microtubular, guiding catheter and rotates haemostatic valve; the external diameter of described microtubular is less than the internal diameter of guiding catheter; described microtubular is pushed to blood embolization place along guiding catheter in guiding catheter; described protection sheath pipe is interconnected with microtubular by rotating haemostatic valve; the described bolt device that takes is placed in protection sheath pipe; it is pushed in microtubular by described conveying silk, and is pushed to blood embolization place.
Further, described conveying silk is made up of the soft tinsel with certain rigidity.
Further, described protection sheath pipe is made up of polymeric material.
Compared with prior art, taking thrombus device with semi-closed structure and the thrombus treating apparatus thereof of the present invention provide the benefit that: by taking the pyramidal structure of bolt device near-end closing and the design with axial clearance that far-end is open, make to take the advantage that bolt device has opening and sealing concurrently simultaneously, maintain the advantage that open cell grid compliance is good, add simultaneously and close the feature that tapered portion propelling movement property is good. Meanwhile, far-end semi-open, semi-enclosed can limitedly fold, and makes thrombosis be less susceptible to come off. On the other hand, structurally do not increase extra parts, just can reach this purpose only by changing shape, it is easy to processing.
Accompanying drawing explanation
Fig. 1 is the structural representation of the thrombus treating apparatus of the blood vessel with semi-closed structure of the present invention;
The bolt device that takes that Fig. 2 is in Fig. 1 is accommodated in the viewgraph of cross-section protected in sheath pipe;
Fig. 3 is the schematic perspective view taking bolt device of the present invention;
Fig. 4 is the expansion schematic diagram taking bolt device first embodiment of Fig. 3;
Fig. 5 be Fig. 4 take the schematic perspective view that bolt device is under free state;
Fig. 6 is the expansion schematic diagram taking bolt device the second embodiment of Fig. 3;
Fig. 7 be Fig. 6 take the schematic perspective view that bolt device is under free state;
Fig. 8 is the size relationship schematic diagram of the unit grid of Fig. 4.
Detailed description of the invention
In order to make the technical problem to be solved, technical scheme and beneficial effect clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated. Should be appreciated that specific embodiment described herein is only in order to explain the present invention, is not intended to limit the present invention.
In the terms of the present invention, " far-end " and " near-end " is appreciated that and observes from the direction of the doctor in charge. Far-end is remote from the side of the doctor in charge, and it relates to the parts of the apparatus of the present invention being advanced in vascular system further, and near-end represents towards the doctor in charge, i.e. it is not far that the nearside arrangement component of this device is introduced in blood vessel.
In the present invention, if phrase " longitudinal direction " is with in this document, it is to be understood as the direction representing that apparatus of the present invention are pushed into, and the longitudinal axis of this device also overlaps along the longitudinal axis of its blood vessel moved forward with this device.It is defined as axially with longitudinally perpendicular direction.
Shown in Fig. 1 and Fig. 3, a kind of taking thrombus device with semi-closed structure of the present invention, including taking bolt device 100, being positioned at the developing ring 300 taking bolt device 100 near-end and be positioned at the development circle 200 taking bolt device 100 far-end. Take webmaster shape or cage structure that bolt device 100 includes being made up of multiple unit grids 170 being coupled to each other, each unit grid 170 by interconnective muscle 120 around forming. This webmaster shape or cage structure can be collapsed folding under pressure and have self-expanding recovery capability in a free state, and, this webmaster shape or collapsing of cage structure fold and expand and can mutually change without difficulty.
The proximal end taking bolt device 100 described under self-expanding state is arranged to pyramidal structure 130, its proximate expand gradually. In the present invention, the tapering of pyramidal structure 130 is 30 ° to 60 °. The near-end pyramidal structure 130 taking bolt device 100 is to close, and is provided with axial clearance 160 on the side of its far-end. Open be interpreted as unit grid 170 be interconnected to do not close, there are webmaster shape or the cage structure of open axial clearance 160 in its side, this axial clearance 160 has at least a place, it is possible to design has many places. The axial clearance 160 embodiment design of the present invention is a place, as shown in figure 5 and figure 7. Utilizing this structure, the pyramidal structure 130 taking bolt device 100 closing can fold easily, and when taking bolt device 100 and moving, can play good supporting role; Open unit grid 170 can make to take bolt device 100 entirety and become submissiveer, tortuous blood vessel can be easily passed through, and open far-end can fold more by a small margin, strengthen and take the bolt device 100 grasping ability to thrombosis, make thrombosis be less susceptible to come off, effectively prevent thrombus breaks loose from flowing to the blood vessel that far-end is more tiny.
The open architecture of the axial clearance 160 taking bolt device 100 has numerous embodiments, The present invention gives following several embodiment:
Embodiment one, as shown in Figures 3 to 5: the pyramidal structure 130 taking bolt device 100 is to close, and remainder is wide-open, and axial clearance 160 is the longest. With this structure, the pyramidal structure 130 of closing can keep good pulling property, makes to take bolt device 100 and can draw in microtubular easily, also can for taking the bolt device 100 support advancing offer good in microtubular. Open unit grid 170 makes to take bolt device 100 entirety and becomes submissiveer, can be easier to by tortuous blood vessel, and can slightly fold at far-end, make thrombosis be less susceptible to come off.
Embodiment two, as shown in Fig. 6 and Fig. 7: it is one semi-open, one semiclosed for taking the unit grid 170 of bolt device 100, and the length of axial clearance 160 occupies about the half of bolt device 100. So can so that take the advantage that bolt device 100 has opening and sealing concurrently simultaneously, the advantage that open cell grid 170 easily folds can be had, also can have the advantage that closed cell lattice 170 propelling movement property is good, further, the quantity (being equivalent to adjust the length of axial clearance 160) of the unit grid 170 closed by adjustment regulates the overall compliance taking bolt device and propelling movement property.
The near-end taking bolt device 100 is arranged to pyramidal structure 130, proximate expand gradually, and its tapering is 30 ° to 60 °. The advantage of this design is can greatly to reduce propelling resistance when taking bolt device 100 and reclaiming into guiding catheter.
Taking bolt device 100 and have oblong shape or oblong shape under self-expanding state, its length range is between 5 millimeters to 60 millimeters, and its diameter range is between 2 millimeters to 6 millimeters, to adapt to the anatomical structure of patient's intracranial vessel.
Refer to shown in Fig. 8, the ratio of the length L1 of unit grid 170 and height H1, more than 1 and less than 2, is similar to diamond structure, and the advantage of this structure is easy to deformation, taking bolt device self-expanding expansion and retraction can be readily accomplished when subsiding folding.
The surface-coated taking bolt device 100 has the coating containing anticoagulant or antiplatelet drug, to strengthen the mobility of blood, it is simple to take pushing of bolt device.
Developing ring 300 and development circle 200 all by can be visual under X ray material make, it is preferable that for platinum, platinoiridita, platinum-tungsten alloys, gold, silver etc. The not transmission X-ray label of the type adds to be located at and takes bolt device 100 proximally and distally so that the doctor in charge can monitor by imaging device location relative to each other and therapeutic advance thus improve the accuracy taking bolt. Being connected to the label developing ring with not transmission X-ray taking bolt device two ends and development circle, making to take bolt device can operate visually under the support of digital subtraction angiography system, and makes to take bolt accurately and reliably. Doctor only advances and withdraws this device and just can complete to take bolt operation, with traditional take bolt operation compared with, operation process is greatly simplified, and has both alleviated the workload of doctor, get again the treatment time of preciousness for patient, strive for the more time for reversible ischemic tissue of brain.
Developing ring 300 and development circle 200 are connected with taking bolt device 100 by modes such as welding or crimp or be cementing. This connection should reach certain intensity, it is prevented that takes bolt device 100 and comes off in taking bolt process.
Take bolt device 100 to be made up of shape-memory material. The shape-memory material of indication of the present invention refer in particular to generation be NiTi evanohm. Taking bolt device 100 is adopt NiTi evanohm to make via cut.
Shown in Fig. 1 and Fig. 2; the invention also discloses a kind of thrombus treating apparatus; employ the above-mentioned taking thrombus device with semi-closed structure; this therapeutic instrument also includes protection sheath pipe 400, conveying silk 500, microtubular 600, guiding catheter (not shown) and rotates haemostatic valve (not shown), and the external diameter of microtubular 600 is less than the internal diameter of guiding catheter. Microtubular 600 is pushed to blood embolization place along guiding catheter in guiding catheter; protection sheath pipe 400 is interconnected with microtubular 600 by rotating haemostatic valve; take bolt device 100 and be placed in protection sheath pipe 400, conveying silk 500 be pushed in microtubular 600, and be pushed to blood embolization place. Guiding catheter has ratio for placing protection sheath pipe 400 and the bigger internal diameter of microtubular 600. So, whole thrombosis and be in the bolt device 100 that takes of its swelling state and can move and be placed in guiding catheter. During treating, microtubular 600 is also advanced to usually by guiding catheter, although guiding catheter can be pushed ahead until blood embolization position, but in the blood vessel that inner chamber is little especially, especially in intracranial area, only with the microtubular 600 that diameter is only small, take bolt device 100 and be placed in microtubular 600 and be transported to the enforcement of blood embolization position take bolt operation.
Conveying silk 500 is made up of the soft tinsel with certain rigidity. Should be appreciated that to expect purpose, the far-end of conveying silk 500; especially into intracranial vessel section, it is necessary to have enough rigidity, but simultaneously must be sufficiently flexible or flexible; make them can pass protection sheath pipe 400 or guiding catheter, and be damaged from blood vessel wall. Its length dimension should ensure that and will take pin device and be delivered to the position of thromboembolism.Protection sheath pipe 400 is made up of polymeric material. This polymeric material is politef. The internal diameter of protection sheath pipe 400 and length dimension should ensure that and the soft taking bolt device 100 and conveying silk 500 far-end is held protection wherein.
The foregoing is only presently preferred embodiments of the present invention, not in order to limit the present invention, all any amendment, equivalent replacement and improvement etc. made within the spirit and principles in the present invention, should be included within protection scope of the present invention.
Claims (10)
1. the taking thrombus device with semi-closed structure, including taking bolt device (100), it is positioned at the developing ring (300) taking bolt device (100) near-end and is positioned at the development circle (200) taking bolt device (100) far-end, it is characterized in that, described take webmaster shape or the cage structure that bolt device (100) includes being made up of multiple unit grids (170) being coupled to each other, one or more described unit grids (170) and other adjacent cells grid (170) are formed by connecting, this webmaster shape or cage structure can be collapsed folding under pressure and have self-expanding recovery capability in a free state, and, this webmaster shape or collapsing of cage structure fold and expand and can mutually change, the proximal end taking bolt device (100) described under self-expanding state is arranged to pyramidal structure (130), its proximate expand gradually, the described near-end pyramidal structure (130) taking bolt device (100) is to close, and is provided with axial clearance (160) on the side of its far-end.
2. the taking thrombus device with semi-closed structure as claimed in claim 1, it is characterized in that, the described bolt device (100) that takes has oblong shape or oblong shape under self-expanding state, its length range is between 5 millimeters to 60 millimeters, and its diameter range is between 2 millimeters to 6 millimeters.
3. the taking thrombus device with semi-closed structure as claimed in claim 2, it is characterised in that the length (L1) of described unit grid (170) and the ratio of height (H1) are more than 1 and less than 2.
4. the taking thrombus device with semi-closed structure as claimed in claim 1, it is characterised in that described in take the surface-coated of bolt device (100) and have the coating containing anticoagulant or antiplatelet drug.
5. the taking thrombus device with semi-closed structure as claimed in claim 1, it is characterised in that described developing ring (300) and development enclose (200) all by can be visual under X ray material make.
6. the taking thrombus device with semi-closed structure as claimed in claim 5, it is characterised in that described developing ring (300) and development circle (200) are connected with taking bolt device (100) by modes such as welding or crimp or be cementing.
7. the taking thrombus device with semi-closed structure as claimed in claim 1, it is characterised in that described in take bolt device (100) and be made up of shape-memory material.
8. a thrombus treating apparatus, it is characterized in that, employ the taking thrombus device with semi-closed structure as described in any one in Claims 1-4, this therapeutic instrument also includes protection sheath pipe (400), conveying silk (500), microtubular (600), guiding catheter and rotation haemostatic valve, the external diameter of described microtubular (600) is less than the internal diameter of guiding catheter, described microtubular (600) is pushed to blood embolization place along guiding catheter in guiding catheter, described protection sheath pipe (400) is interconnected with microtubular (600) by rotating haemostatic valve, the described bolt device (100) that takes is placed in protection sheath pipe (400), it is pushed in microtubular (600) by described conveying silk (500), and it is pushed to blood embolization place.
9. thrombus treating apparatus as claimed in claim 8, it is characterised in that described conveying silk (500) is made up of the soft tinsel with certain rigidity.
10. thrombus treating apparatus as claimed in claim 8, it is characterised in that described protection sheath pipe (400) is made up of polymeric material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610006988.1A CN105662532A (en) | 2016-01-06 | 2016-01-06 | Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610006988.1A CN105662532A (en) | 2016-01-06 | 2016-01-06 | Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105662532A true CN105662532A (en) | 2016-06-15 |
Family
ID=56299209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610006988.1A Pending CN105662532A (en) | 2016-01-06 | 2016-01-06 | Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105662532A (en) |
Cited By (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105997314A (en) * | 2016-06-30 | 2016-10-12 | 魏诗荣 | Thrombus removing system with compound function |
| CN106580397A (en) * | 2016-12-20 | 2017-04-26 | 北京久事神康医疗科技有限公司 | Sectional thrombus extraction device and thrombus extraction method making use of thrombus extraction device |
| CN106725723A (en) * | 2016-12-14 | 2017-05-31 | 苏州斯恩维医疗科技有限公司 | One kind takes bolt mounting system |
| CN106859729A (en) * | 2017-03-10 | 2017-06-20 | 上海心玮医疗科技有限公司 | One kind takes bolt mounting system |
| CN106955140A (en) * | 2017-05-09 | 2017-07-18 | 心凯诺医疗科技(上海)有限公司 | One kind takes bolt support and thrombus withdrawing device |
| CN107137125A (en) * | 2017-06-20 | 2017-09-08 | 微创神通医疗科技（上海）有限公司 | Take bolt support and take pin device |
| CN107361816A (en) * | 2017-08-16 | 2017-11-21 | 朱玉红 | A kind of pulmonary embolism protection dispels device with thrombus |
| CN109124837A (en) * | 2018-07-06 | 2019-01-04 | 淮阴工学院 | A kind of encephalic of imitative fish scale-shaped takes bolt bracket |
| CN109793553A (en) * | 2019-02-02 | 2019-05-24 | 恩脉（上海）医疗科技有限公司 | One kind taking bolt rack and takes pin device |
| CN109906058A (en) * | 2016-09-06 | 2019-06-18 | 尼尔拉维有限公司 | Clot retrieval device for removing an occluded clot from a blood vessel |
| CN109938801A (en) * | 2017-12-21 | 2019-06-28 | 新昕医药科技（上海）有限公司 | A kind of thrombus takes bolt device |
| CN110711011A (en) * | 2018-07-12 | 2020-01-21 | 先健科技(深圳)有限公司 | Thrombus taking device |
| CN111956301A (en) * | 2020-09-07 | 2020-11-20 | 北京阳立医疗科技有限公司 | Thrombus extraction device and manufacturing method thereof |
| CN112438777A (en) * | 2019-08-28 | 2021-03-05 | 尤东侠 | Minimally invasive thrombus extraction device for treating vascular embolism |
| CN112674839A (en) * | 2020-12-31 | 2021-04-20 | 北京管桥医疗科技有限公司 | Thrombus taking device for pulmonary artery embolism |
| US11103264B2 (en) | 2013-03-14 | 2021-08-31 | Neuravi Limited | Devices and methods for removal of acute blockages from blood vessels |
| US11246612B2 (en) | 2010-10-22 | 2022-02-15 | Neuravi Limited | Clot engagement and removal system |
| US11253278B2 (en) | 2014-11-26 | 2022-02-22 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
| US11259824B2 (en) | 2011-03-09 | 2022-03-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| US11395669B2 (en) | 2020-06-23 | 2022-07-26 | Neuravi Limited | Clot retrieval device with flexible collapsible frame |
| US11406416B2 (en) | 2018-10-02 | 2022-08-09 | Neuravi Limited | Joint assembly for vasculature obstruction capture device |
| US11439418B2 (en) | 2020-06-23 | 2022-09-13 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| CN115317077A (en) * | 2022-10-13 | 2022-11-11 | 成都百瑞恒通医疗科技有限公司 | Thrombus taking device |
| US11517340B2 (en) | 2019-12-03 | 2022-12-06 | Neuravi Limited | Stentriever devices for removing an occlusive clot from a vessel and methods thereof |
| US11529157B2 (en) | 2008-07-22 | 2022-12-20 | Neuravi Limited | Clot capture systems and associated methods |
| US11547427B2 (en) | 2013-03-14 | 2023-01-10 | Neuravi Limited | Clot retrieval devices |
| US11712256B2 (en) | 2014-11-26 | 2023-08-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| US11712231B2 (en) | 2019-10-29 | 2023-08-01 | Neuravi Limited | Proximal locking assembly design for dual stent mechanical thrombectomy device |
| US11717308B2 (en) | 2020-04-17 | 2023-08-08 | Neuravi Limited | Clot retrieval device for removing heterogeneous clots from a blood vessel |
| US11730501B2 (en) | 2020-04-17 | 2023-08-22 | Neuravi Limited | Floating clot retrieval device for removing clots from a blood vessel |
| US11737771B2 (en) | 2020-06-18 | 2023-08-29 | Neuravi Limited | Dual channel thrombectomy device |
| US11839392B2 (en) | 2013-03-14 | 2023-12-12 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11857210B2 (en) | 2014-11-26 | 2024-01-02 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11864781B2 (en) | 2020-09-23 | 2024-01-09 | Neuravi Limited | Rotating frame thrombectomy device |
| US11871946B2 (en) | 2020-04-17 | 2024-01-16 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11937837B2 (en) | 2020-12-29 | 2024-03-26 | Neuravi Limited | Fibrin rich / soft clot mechanical thrombectomy device |
| US11937836B2 (en) | 2020-06-22 | 2024-03-26 | Neuravi Limited | Clot retrieval system with expandable clot engaging framework |
| US11974764B2 (en) | 2021-06-04 | 2024-05-07 | Neuravi Limited | Self-orienting rotating stentriever pinching cells |
| US11998223B2 (en) | 2011-03-09 | 2024-06-04 | Neuravi Limited | Clot retrieval device for removing a clot from a blood vessel |
| US12029442B2 (en) | 2021-01-14 | 2024-07-09 | Neuravi Limited | Systems and methods for a dual elongated member clot retrieval apparatus |
| US12064130B2 (en) | 2021-03-18 | 2024-08-20 | Neuravi Limited | Vascular obstruction retrieval device having sliding cages pinch mechanism |
| US12076037B2 (en) | 2011-03-09 | 2024-09-03 | Neuravi Limited | Systems and methods to restore perfusion to a vessel |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514273B1 (en) * | 2000-03-22 | 2003-02-04 | Endovascular Technologies, Inc. | Device for removal of thrombus through physiological adhesion |
| US20050267491A1 (en) * | 2003-04-02 | 2005-12-01 | James Kellett | Embolectomy devices |
| CN102596098A (en) * | 2009-07-08 | 2012-07-18 | 同心医疗公司 | Vascular and bodily duct treatment devices and methods |
| CN203379185U (en) * | 2013-06-04 | 2014-01-08 | 加奇生物科技(上海)有限公司 | Intracranial thrombus removing device |
| CN103547224A (en) * | 2011-05-13 | 2014-01-29 | 菲诺克斯有限公司 | Thrombectomy device |
| CN205359559U (en) * | 2016-01-06 | 2016-07-06 | 赵烜 | Blood vessel thrombectomy device and thrombus therapeutic instrument with semi -closed structure |
-
2016
- 2016-01-06 CN CN201610006988.1A patent/CN105662532A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514273B1 (en) * | 2000-03-22 | 2003-02-04 | Endovascular Technologies, Inc. | Device for removal of thrombus through physiological adhesion |
| US20050267491A1 (en) * | 2003-04-02 | 2005-12-01 | James Kellett | Embolectomy devices |
| CN102596098A (en) * | 2009-07-08 | 2012-07-18 | 同心医疗公司 | Vascular and bodily duct treatment devices and methods |
| CN103547224A (en) * | 2011-05-13 | 2014-01-29 | 菲诺克斯有限公司 | Thrombectomy device |
| CN203379185U (en) * | 2013-06-04 | 2014-01-08 | 加奇生物科技(上海)有限公司 | Intracranial thrombus removing device |
| CN205359559U (en) * | 2016-01-06 | 2016-07-06 | 赵烜 | Blood vessel thrombectomy device and thrombus therapeutic instrument with semi -closed structure |
Cited By (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11529157B2 (en) | 2008-07-22 | 2022-12-20 | Neuravi Limited | Clot capture systems and associated methods |
| US11871949B2 (en) | 2010-10-22 | 2024-01-16 | Neuravi Limited | Clot engagement and removal system |
| US11246612B2 (en) | 2010-10-22 | 2022-02-15 | Neuravi Limited | Clot engagement and removal system |
| US12076037B2 (en) | 2011-03-09 | 2024-09-03 | Neuravi Limited | Systems and methods to restore perfusion to a vessel |
| US11998223B2 (en) | 2011-03-09 | 2024-06-04 | Neuravi Limited | Clot retrieval device for removing a clot from a blood vessel |
| US12059164B2 (en) | 2011-03-09 | 2024-08-13 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| US11259824B2 (en) | 2011-03-09 | 2022-03-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| US11839392B2 (en) | 2013-03-14 | 2023-12-12 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11871945B2 (en) | 2013-03-14 | 2024-01-16 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11937835B2 (en) | 2013-03-14 | 2024-03-26 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11103264B2 (en) | 2013-03-14 | 2021-08-31 | Neuravi Limited | Devices and methods for removal of acute blockages from blood vessels |
| US11547427B2 (en) | 2013-03-14 | 2023-01-10 | Neuravi Limited | Clot retrieval devices |
| US11980379B2 (en) | 2014-11-26 | 2024-05-14 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
| US11253278B2 (en) | 2014-11-26 | 2022-02-22 | Neuravi Limited | Clot retrieval system for removing occlusive clot from a blood vessel |
| US11712256B2 (en) | 2014-11-26 | 2023-08-01 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| US11857210B2 (en) | 2014-11-26 | 2024-01-02 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| CN105997314A (en) * | 2016-06-30 | 2016-10-12 | 魏诗荣 | Thrombus removing system with compound function |
| US11147572B2 (en) | 2016-09-06 | 2021-10-19 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| CN109906058B (en) * | 2016-09-06 | 2022-06-07 | 尼尔拉维有限公司 | Clot retrieval device for removing an occluded clot from a blood vessel |
| CN109906058A (en) * | 2016-09-06 | 2019-06-18 | 尼尔拉维有限公司 | Clot retrieval device for removing an occluded clot from a blood vessel |
| US12133657B2 (en) | 2016-09-06 | 2024-11-05 | Neuravi Limited | Clot retrieval device for removing occlusive clot from a blood vessel |
| CN106725723A (en) * | 2016-12-14 | 2017-05-31 | 苏州斯恩维医疗科技有限公司 | One kind takes bolt mounting system |
| CN106580397A (en) * | 2016-12-20 | 2017-04-26 | 北京久事神康医疗科技有限公司 | Sectional thrombus extraction device and thrombus extraction method making use of thrombus extraction device |
| CN106859729A (en) * | 2017-03-10 | 2017-06-20 | 上海心玮医疗科技有限公司 | One kind takes bolt mounting system |
| CN106955140A (en) * | 2017-05-09 | 2017-07-18 | 心凯诺医疗科技(上海)有限公司 | One kind takes bolt support and thrombus withdrawing device |
| CN107137125B (en) * | 2017-06-20 | 2023-08-04 | 微创神通医疗科技（上海）有限公司 | Bolt taking support and bolt taking device |
| CN107137125A (en) * | 2017-06-20 | 2017-09-08 | 微创神通医疗科技（上海）有限公司 | Take bolt support and take pin device |
| CN107361816B (en) * | 2017-08-16 | 2023-08-22 | 朱玉红 | Pulmonary embolism protection and thrombus removing device |
| CN107361816A (en) * | 2017-08-16 | 2017-11-21 | 朱玉红 | A kind of pulmonary embolism protection dispels device with thrombus |
| CN109938801A (en) * | 2017-12-21 | 2019-06-28 | 新昕医药科技（上海）有限公司 | A kind of thrombus takes bolt device |
| CN109124837A (en) * | 2018-07-06 | 2019-01-04 | 淮阴工学院 | A kind of encephalic of imitative fish scale-shaped takes bolt bracket |
| CN110711011A (en) * | 2018-07-12 | 2020-01-21 | 先健科技(深圳)有限公司 | Thrombus taking device |
| US11963693B2 (en) | 2018-10-02 | 2024-04-23 | Neuravi Limited | Joint assembly for vasculature obstruction capture device |
| US11406416B2 (en) | 2018-10-02 | 2022-08-09 | Neuravi Limited | Joint assembly for vasculature obstruction capture device |
| CN109793553A (en) * | 2019-02-02 | 2019-05-24 | 恩脉（上海）医疗科技有限公司 | One kind taking bolt rack and takes pin device |
| CN112438777A (en) * | 2019-08-28 | 2021-03-05 | 尤东侠 | Minimally invasive thrombus extraction device for treating vascular embolism |
| US11712231B2 (en) | 2019-10-29 | 2023-08-01 | Neuravi Limited | Proximal locking assembly design for dual stent mechanical thrombectomy device |
| US12004731B2 (en) | 2019-10-29 | 2024-06-11 | Neuravi Limited | Proximal locking assembly design for dual stent mechanical thrombectomy device |
| US12023058B2 (en) | 2019-12-03 | 2024-07-02 | Neuravi Limited | Stentriever devices for removing an occlusive clot from a vessel and methods thereof |
| US11517340B2 (en) | 2019-12-03 | 2022-12-06 | Neuravi Limited | Stentriever devices for removing an occlusive clot from a vessel and methods thereof |
| US11871946B2 (en) | 2020-04-17 | 2024-01-16 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| US11717308B2 (en) | 2020-04-17 | 2023-08-08 | Neuravi Limited | Clot retrieval device for removing heterogeneous clots from a blood vessel |
| US12048446B2 (en) | 2020-04-17 | 2024-07-30 | Neuravi Limited | Clot retrieval device for removing heterogeneous clots from a blood vessel |
| US11730501B2 (en) | 2020-04-17 | 2023-08-22 | Neuravi Limited | Floating clot retrieval device for removing clots from a blood vessel |
| US11737771B2 (en) | 2020-06-18 | 2023-08-29 | Neuravi Limited | Dual channel thrombectomy device |
| US11937836B2 (en) | 2020-06-22 | 2024-03-26 | Neuravi Limited | Clot retrieval system with expandable clot engaging framework |
| US11395669B2 (en) | 2020-06-23 | 2022-07-26 | Neuravi Limited | Clot retrieval device with flexible collapsible frame |
| US11439418B2 (en) | 2020-06-23 | 2022-09-13 | Neuravi Limited | Clot retrieval device for removing clot from a blood vessel |
| CN111956301A (en) * | 2020-09-07 | 2020-11-20 | 北京阳立医疗科技有限公司 | Thrombus extraction device and manufacturing method thereof |
| US11864781B2 (en) | 2020-09-23 | 2024-01-09 | Neuravi Limited | Rotating frame thrombectomy device |
| US11937837B2 (en) | 2020-12-29 | 2024-03-26 | Neuravi Limited | Fibrin rich / soft clot mechanical thrombectomy device |
| CN112674839A (en) * | 2020-12-31 | 2021-04-20 | 北京管桥医疗科技有限公司 | Thrombus taking device for pulmonary artery embolism |
| US12029442B2 (en) | 2021-01-14 | 2024-07-09 | Neuravi Limited | Systems and methods for a dual elongated member clot retrieval apparatus |
| US12064130B2 (en) | 2021-03-18 | 2024-08-20 | Neuravi Limited | Vascular obstruction retrieval device having sliding cages pinch mechanism |
| US11974764B2 (en) | 2021-06-04 | 2024-05-07 | Neuravi Limited | Self-orienting rotating stentriever pinching cells |
| CN115317077A (en) * | 2022-10-13 | 2022-11-11 | 成都百瑞恒通医疗科技有限公司 | Thrombus taking device |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN205359559U (en) | Blood vessel thrombectomy device and thrombus therapeutic instrument with semi -closed structure | |
| CN105662532A (en) | Blood-vessel embolectomy device with semi-closed structure and thrombus treating apparatus with the same | |
| CN105662534A (en) | Blood vessel thrombus-taking device with spine-shaped structures and thrombus therapeutic instrument thereof | |
| CN105662533A (en) | Blood-vessel embolectomy device with helical structure and thrombus treating apparatus with the same | |
| CN103284775B (en) | Encephalic thrombosis removing device | |
| CN111904675B (en) | Thrombus taking support and thrombus capturing device | |
| CN106618676B (en) | Intravascular thrombus taking-out device | |
| CN205359560U (en) | Blood vessel thrombectomy device and thrombus therapeutic instrument with helical structure | |
| JP6873233B2 (en) | Blood clot collection device for the treatment of ischemic stroke | |
| JP5914432B2 (en) | Recovery system and method of use | |
| CN203379185U (en) | Intracranial thrombus removing device | |
| CN112384152A (en) | Device and method for removing substance from a patient | |
| CN216125035U (en) | Novel vein thrombus taking catheter | |
| CN213641088U (en) | Intravascular thrombus capture device | |
| WO2010146581A1 (en) | Method and apparatus for allowing blood flow through an occluded vessel | |
| WO2012009675A2 (en) | Retrieval systems and methods for use thereof | |
| CN114391917B (en) | Diameter-variable thrombus taking device and use method thereof | |
| CN105455878A (en) | Catching device | |
| CN205339057U (en) | Blood vessel thrombectomy device and thrombus therapeutic instrument with thorn column structure | |
| KR20210122134A (en) | Catheter funnel extension | |
| US20160089227A1 (en) | Clot and foreign body retrieval system and method for use | |
| CN217244648U (en) | Variable-diameter plug taking device | |
| CN206675575U (en) | A kind of Intravascular Thrombus withdrawing device | |
| CN115737059A (en) | Spiral type non-cutting bolt taking device | |
| CN111053594B (en) | Thrombus taking device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160711 Address after: 519000, building sixth, room 603, room 10, main building, No. 1, science and technology road, Harbour Road, Tang Wan Town, Guangdong, Zhuhai, Applicant after: Zhuhai trans Bridge Medical Technology Co., Ltd. Address before: 311121, No. 1, 18 science Avenue, Yuhang street, Yuhang District, Zhejiang, Hangzhou Applicant before: Zhao Hui |
|
| CB03 | Change of inventor or designer information |
Inventor after: Zhao Zhong Inventor before: Zhao Zhong Inventor before: Chen Zhigang Inventor before: Xu Bingke Inventor before: Shi Lei |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160615 |