CN105125338A - Medical instrument for relieving eyeground vasculopathy and control method of medical instrument - Google Patents
Medical instrument for relieving eyeground vasculopathy and control method of medical instrument Download PDFInfo
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- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
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Abstract
The invention discloses a medical instrument for relieving eyeground vasculopathy and a control method of the medical instrument, aiming to solve the problem that existing devices affect sleeping of users. The medical instrument comprises an MCU (micro-programmed control unit), an optical treatment module, a wearing state monitoring module, a sleeping monitoring module and a power module. The MCU is used for centralized module control and processing. The optical treatment module comprises an optical source driving module and an optical source array. The optical source driving module is used for receiving control commands generated by the MCU, amplifying power and driving the optical source array. The wearing state monitoring module is used for monitoring the wearing state of the instrument in real time. The sleeping monitoring module is used for measuring pulse wave signals of patients, performing AD (analog to digital) conversion on the signals and transmitting the converted signals to the MCU which monitors the sleeping states of the patients according to a sleeping state monitoring algorithm. The power module provides a stable power supply for the instrument. The medical instrument has the advantages that the optical treatment mode is adjusted according to the sleeping states of the users, disturbance on sleeping quality of the users is avoided and the like.
Description
Technical field
The present invention relates to a kind of medical treatment device, what be specifically related to is a kind of medical treatment device alleviating Fundus oculi lesion, and provides the control method of this device.
Background technology
The harm of diabetic eye disease: diabetic eye disease is the modal complication of diabetes, comprises diabetic macular edema, retinopathy etc. is the blind most common cause of adult's preventability.Epidemiological investigation data according to diabetology branch of Chinese Medical Association and Society of Ophthalmology shows, in China, within more than 20 years old, adult's diabetes prevalence is 9.7%, be the country [1] that diabetics number is maximum in the world, the prevalence of retinopathy in diabetics crowd is 24.7% ~ 37.5%.
The pathogeny of diabetic eye disease: Medical bound pair lacks comprehensively understanding in the pathogeny of diabetic ophthalmic, but a large amount of clinical test results shows, diabetics a series of chain reactions of causing of Advanced Glycation end-product (AGEs) with it, VEGF (VEGF) undue growth can be aggravated, and then cause retinopathy and vision decline.
Traditional treatment means and shortcoming: the outer treatment means for diabetic eye disease of Present Domestic is mainly divided into two kinds: laser surgery and VEGF suppress (anti-VEGF) medicine intravitreal injection.But laser therapy is poor effect in vision restoration, even if successful surgery, patient's vision declines and usually also can aggravate after five years.Anti-VEGF medicine (as Lucentis) costly, and needs to implement repeatedly vitreous body drug injection, causes whole treatment cost very high.The more important thing is, these two kinds of methods all could can only be implemented when retinopathy is comparatively serious usually.
The know-why of new treatment means and advantage: the computer MSR Information system of Britain ophthalmologist professor GeoffreyBernardArden leader thinks that histanoxia that retinal rod dark adaptation causes is the main cause of VEGF undue growth, and by the clinical research of nearly 20 years, demonstrate and can weaken columnar cell dark adaptation process by phototherapy, suppress VEGF undue growth, and then reach the object of diabetes-alleviating retinopathy.For laser surgery and these two kinds of traditional treatment modes of vitreous body drug injection, phototherapy be diabetic eye disease provide a kind of complete noinvasive, with low cost, easy to implement, can just carry out the new treatment means of intervening in early days in pathological changes.
The deficiency of new treatment means: phototherapy of the prior art is all adopt the mode of direct irradiation to treat ophthalmic, cannot regulate intensity of illumination, and in the similar device disclosed in WO2011/135362, CN103596621 and CN104245047, it improves in comfort level and motility, by place luminous source box body, have less caloric value luminous source (OLED lamp), the controller of luminous source parameter (as brightness, operating time etc.) and determining device can be regulated whether to be formed by the sensor nucleus module worn.But the light source still existing defects that device after this improvement is launched, namely do not sleep or shallow dormancy state time, stronger light intensity to producing interference to the sleep of wearer, or surprisingly wake the wearer fallen asleep up.
Summary of the invention
The object of the invention is to overcome device in prior art to regulate intensity of illumination according to user's sleep quality, and then affect the problem of user rest; A kind of device alleviating Fundus oculi lesion solved the problem is provided, and discloses the control method of this device.
For achieving the above object, technical scheme of the present invention is as follows:
Alleviate a medical treatment device for Fundus oculi lesion, comprising:
MCU controller: center controls and processing module;
Light treatment module: wherein comprise light source driver module and array of source two parts, the control instruction that light source driver module generates for receiving MCU controller, carry out power amplification and driving light source array light-emitting, in the present invention, light source is the device can launching device desirable strength and wavelength light, and it can use but be not limited only to the light-emitting components such as LED and OLED;
Wearing state monitoring modular: Real-Time Monitoring is carried out to the wearing state of device, whether this module can fit with human body by induction installation preferably, thus monitoring wearing state, it can use but be not limited only to the elements such as capacitive touch sensor, infrared ray proximity switch and pressure transducer;
Sleep monitor module: measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm, and regulate light Therapeutic mode according to sleep state; This module can not affect in patient sleeps's situation for all, and non-invasively measure the sensor assembly of patient pulse's ripple signal, it includes but are not limited to photoplethysmographic sensor;
Power module: for device provides stable power supply.
The principle alleviating Fundus oculi lesion is: suppress principle based on retinal rod dark adaptation, thus helps diabetics relieving retina pathological changes.The present invention measures patient pulse's ripple signal by sleep monitor module, and according to detecting that pulse wave signal realizes continuous detecting and the tracking of patient sleeps's state by sleep state monitoring algorithm, and then the light source parameters of module is treated according to patient sleeps's status adjustment light, effectively avoid illumination to the state of not sleeping and high light the wearer to shallow dormancy state sleep produce interference, strengthen the intensity of illumination under parasomnia simultaneously, improve therapeutic effect.
The invention also discloses a kind of control method alleviating the medical treatment device of Fundus oculi lesion, it specifically comprises the following steps:
(1) adopt the wear condition of wearing state monitoring modular checkout gear, if do not wear, then proceed monitoring, if worn, then enter next step;
(2) adopt sleep monitor module to measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm;
(3) if do not enter sleep state, then light treatment module is not opened; If enter sleep state, then judge that this sleep state is rapid-eye-movement sleep (REM sleep) state or nonrapid eye movements,sleep state, open light treatment module according to sleep state.
Further, device of the present invention also comprises:
Control terminal: the usage data passed back for receiving system, and wirelessly device is controlled;
Data transmission module: in order to follow the transmitting-receiving carrying out control instruction and usage data between control terminal with communication, it can use but be not limited only to bluetooth module, WIFI module etc.;
Data recordin module: the usage data of recording user;
Clock module: for generation of system time and date and time information, namely for obtaining the information such as use initial time, use duration of user;
Described power module is rechargable power supplies module, and it is made up of rechargeable type lithium battery and peripheral charge-discharge circuit.Wherein clock module, data recordin module and data transmission module are all integrated in device.
Before device is worn, first can be arranged by the running parameter of control terminal to light treatment module, and then wear, detailed process is:
A () is by data transmission module connection control terminal and device;
(b) running parameter of setting device on control terminal, and by data transmission module, running parameter is sent in MCU controller, after wearing, control according to the monitoring result of running parameter and wearing state monitoring modular and sleep monitor module the work that light treats module again, and treated the work service condition of module by data recordin module recording light;
C, after () light treatment module from service, the work service condition of recording light being treated module is transferred to control terminal by data transmission module.
Further, in order to improve level of comfort when wearing while being effective, described device is arranged in the eye hood configuration be made up of three-decker, and the three-decker of this hood configuration is respectively internal layer, middle level and skin; Wherein, internal layer eyes place respectively arranges a luminescence window, and this internal layer upper left quarter is provided with wears monitoring sensor arrangement window, and internal layer upper right quarter is then provided with sleep monitor module and settles window; This middle level is hardware layer, connected by holding wire by two pieces of circuit boards, described circuit board is provided with light with luminescence window correspondence position and treats module, with wear monitoring sensor and settle window correspondence position that wearing state monitoring modular is installed, settle window correspondence position that sleep monitor module is installed with sleep monitor module, this circuit board is gone back integrated power supply module, MCU controller, data transmission module, data recordin module and clock module; Described skin arranges heat dissipation region; The eye hood configuration left and right sides is connected by elastic band.
Because the pulse wave signal of sleep detection instrument in prior art is all record from toe or finger position, if gather pulse wave signal from toe or finger position, pass to MCU controller again to monitor sleep state, then destroy the integrity of device, and can affect greatly user sleep.
Thus in order to intensifier integrity and avoid impacting user sleep, sleep detection appliance requires of the present invention is in a device integrated, around eye, obtain the pulse wave signal of measurement simultaneously.
The wide variety of pulse wave harvester, is made up of a pair light emitting diode (LED) and receiving tube usually.Luminous tube launch constant light source, wavelength is about the infrared light of 940nm, this infrared light upper epidermis and and skin corium arrive arteries, then through reflection or transmission after arrive receiving tube.Because transmitting illuminant is constant, receive the impact of intensity by arteries volume change of light, therefore can extract arteries capacity in the regular pollex information of each cardiac cycle from the change of receiving light power degree, i.e. pulse wave signal.
Because of forehead position blood vessel comparatively horn of plenty, prop up before comprising blood vessel on left temporo blood vessel, right temporo blood vessel, socket of the eye, Temporal Artery.In order to strengthen the accuracy of measurement of pulse wave signal, the instrument measuring patient pulse's ripple signal described in the present invention is preferably reflection type photoelectricity volume pulsation wave sensor, all can record pulse wave signal by this reflection type photoelectricity volume pulsation wave sensor in left temporo, right temporo and forehead middle and lower part, meet user demand.
Because tempori sinistro effective range is wider, the amount of movement that wearer such as to stand up at the eyeshield caused is limited, and so long as not generation eyeshield severe detachment, sensor still can record pulse wave signal.Thus the present invention selects to place sensor measurement pulse wave signal in tempori sinistro position.
In order to improve accuracy of measurement, present invention optimizes sleep state monitoring algorithm, adopt more careful signal processing algorithm and decision tree mechanism, only need to use pulse wave signal just can distinguish awakening, rapid eye movement phase sleep (shallow sleep), nonrapid eye movements (NREM) phase sleep (deep sleep) three kinds of states.The process of the monitoring algorithm of sleep state described in the present invention is:
(1) digital band-pass filter of 0.05Hz ~ 20Hz is adopted to carry out Filtering Processing to pulse wave signal; After above-mentioned pretreatment, effectively can eliminate low frequency movement interfering signal and high-frequency circuit interfering signal, improve the precision of pulse wave signal; , move by a small margin because eyeshield in use has, this moves among a small circle can bring certain low-frequency disturbance to pulse wave signal, but by after above-mentioned pretreatment, can effectively avoid this interference meanwhile; Namely this interference effectively can be removed by wave filter in the Signal Pretreatment link of algorithm.
(2) detect each cardiac cycle pulse wave peak value, and extract IPP sequence;
(3) the IPP average Mean_IPP in special time window is asked for;
(4) cubic spline interpolation algorithm is to IPP sequence interpolations;
(5) 4Hz sample rate is to IPP sequential sampling after interpolation;
(6) period map method tries to achieve IPP sequence power spectrum;
(7) extract LF and HF two partial power compose and calculate energy;
(8) the energy ratio LF/HF of LF and HF is asked for;
(9) when LF/HF is greater than threshold value 1, rapid-eye-movement sleep (REM sleep) state is judged to be; When LF/HF is less than or equal to threshold value 1, then enter lower step;
(10) when LF/HF is greater than threshold value 2, nonrapid eye movements,sleep state is judged to be; When LF/HF is less than or equal to threshold value 2, be then judged to be wakefulness.
Two parameter LF/HF that the present invention uses identification best and Mean_IPP implementation decision tree judge, greatly reduce computation complexity, use periodic sequence between step (5) middle 4Hz resampling technique process arteries and veins, improve the precision of power Spectral Estimation.
Further, described threshold value 1 is 1.71, and threshold value 2 is 0.996.Proved by many experiments, under the setting of this threshold value, sleep state monitoring accuracy of the present invention reaches more than 99%.
The present invention compared with prior art, has the following advantages and beneficial effect:
1, the present invention measures patient pulse's ripple signal by sleep monitor module, and realized continuous detecting and the tracking of patient sleeps's state by sleep state monitoring algorithm according to the pulse wave signal detected, and then the light source parameters of module is treated according to patient sleeps's status adjustment light, effectively avoid illumination to the state of not sleeping and high light the wearer to shallow dormancy state sleep produce interference, strengthen the intensity of illumination under parasomnia simultaneously, improve therapeutic effect;
2, the present invention adopts more careful signal processing algorithm and decision tree mechanism, only needs to use pulse wave signal just can distinguish awakening, rapid eye movement phase sleep (shallow sleep), nonrapid eye movements (NREM) phase sleep (deep sleep) three kinds of states; The testing result accuracy rate obtained by above-mentioned signal processing algorithm is better than prior art;
3, the instrument measuring patient pulse's ripple signal in the present invention is preferably reflection type photoelectricity volume pulsation wave sensor, by the setting of this reflection type photoelectricity volume pulsation wave sensor, effective realization obtains the object of patient pulse's ripple signal around eye socket, simultaneously, this arranges the integrity of effective intensifier, and avoid to user sleep impact, improve use comfort.
Accompanying drawing explanation
Fig. 1 is the structure principle chart of the embodiment of the present invention 3.
Fig. 2 is the structural representation of the embodiment of the present invention 4.
Fig. 3 is the flow chart of sleep state monitoring algorithm in the present invention.
Wherein, the parts name that in figure, Reference numeral is corresponding is called:
1-luminescence window, 2-heat dissipation region, 3-wears monitoring sensor and settles window, 4-sleep monitor module settles window, 5-circuit board, 6-holding wire, 7-light treatment module, 8-wearing state monitoring modular, 9-sleep monitor module, 10-power module, 11-MCU controller, 12-data transmission module, 13-data recordin module, 14-clock module.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited thereto.
Embodiment 1
Alleviate a device for Fundus oculi lesion, comprising:
MCU controller: center controls and processing module;
Light treatment module: wherein comprising LED drive module and LED array two parts, the control instruction that LED drive module generates for receiving MCU controller, carrying out power amplification and driving LED array;
Wearing state monitoring modular: use capacitive touch sensor, Real-Time Monitoring is carried out to the wearing state of device;
Sleep monitor module: measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm; This module can not affect in patient sleeps's situation for all, non-invasively measures the sensor assembly of patient pulse's ripple signal.
Power module: for device provides stable power supply.
The work process of device described in the present embodiment is as follows:
(1) adopt the wear condition of wearing state monitoring modular checkout gear, if do not wear, then proceed monitoring, if worn, then enter next step;
(2) adopt sleep monitor module to measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm;
(3) if do not enter sleep state, then light treatment module is not opened; If enter sleep state, then judge that this sleep state is rapid-eye-movement sleep (REM sleep) state or nonrapid eye movements,sleep state, open light treatment module according to sleep state.
By above-mentioned work process, can effectively be confirmed whether to open light treatment module according to the sleep state of user.Namely when sleep state be in do not sleep time, then do not open light treatment module, there is no illumination, can effectively impel user to enter sleep state fast, when user is in either shallow sleep state, then open the part LED in the LED array of light treatment module, reach the object for the treatment of, when user is in deep sleep, then increase the unlatching quantity of the LED in LED array, increase intensity of illumination, effectively improve therapeutic effect.
Embodiment 2
The present embodiment is on the basis of embodiment 1, optimize the instrument measuring patient pulse's ripple signal, and the instrument measuring patient pulse's ripple signal described in the present embodiment is reflection type photoelectricity volume pulsation wave sensor.
Present embodiments provide a kind of sleep state monitoring algorithm, effective simplified operation complexity, improves the accuracy rate of testing result simultaneously, and as shown in Figure 3, this sleep state monitoring algorithm concrete operation process is as follows:
(1) digital band-pass filter of 0.05Hz ~ 20Hz is adopted to carry out Filtering Processing to pulse wave signal;
(2) detect each cardiac cycle pulse wave peak value, and extract IPP sequence;
(3) the IPP average Mean_IPP in special time window is asked for;
(4) cubic spline interpolation algorithm is to IPP sequence interpolations;
(5) 4Hz sample rate is to IPP sequential sampling after interpolation;
(6) period map method tries to achieve IPP sequence power spectrum;
(7) extract LF and HF two partial power compose and calculate energy;
(8) the energy ratio LF/HF of LF and HF is asked for;
(9) when LF/HF is greater than threshold value 1, rapid-eye-movement sleep (REM sleep) state is judged to be; When LF/HF is less than or equal to threshold value 1, then enter lower step, described threshold value 1 is 1.71;
(10) when LF/HF is greater than threshold value 2, nonrapid eye movements,sleep state is judged to be; When LF/HF is less than or equal to threshold value 2, be then judged to be wakefulness; Described threshold value 2 is 0.996.
Wherein, LF(low-frequency range) scope: 0.05 ~ 0.15Hz; HF(high band) scope: 0.15 ~ 0.4Hz; And cubic spline interpolation algorithm, the middle 4Hz sample rate resampling of step (4), the middle period map method of step (5), the middle extracting method of power spectrum of step (6) and the computational methods of energy in step (4) are prior art, therefore repeat no more in this document.
Embodiment 3
The present embodiment adds control terminal on the basis of embodiment 2, and optimize the structure of device, and as shown in Figure 1, it specifically arranges as follows:
Described control terminal, for the usage data that receiving system is passed back, and wirelessly controls device, and the control terminal in the present embodiment is the external control system shown in Fig. 1.
Described device also comprises:
Data transmission module: be Bluetooth communication modules, in order to follow the transmitting-receiving carrying out control instruction and usage data between control terminal;
Data recordin module: the usage data of recording user;
Clock module: for generation of system time and date and time information;
Described power module is rechargable power supplies module, and it is made up of rechargeable type lithium battery and peripheral charge-discharge circuit.
In the present embodiment, a kind of concrete control method alleviating the medical treatment device of Fundus oculi lesion is as follows:
(1) before wearable device, by data transmission module connection control terminal and device;
(2) running parameter of setting device on control terminal, and by data transmission module, running parameter is sent in MCU controller;
(3) adopt the wear condition of wearing state monitoring modular checkout gear, if do not wear, then proceed monitoring, if worn, then enter next step;
(4) adopt sleep monitor module to measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm;
If do not enter sleep state, then do not open light treatment module; If enter sleep state, then judge that this sleep state is rapid-eye-movement sleep (REM sleep) state or nonrapid eye movements,sleep state;
(5) control according to the monitoring result of running parameter and wearing state monitoring modular and sleep monitor module the work that light treats module, and treated the work service condition of module by data recordin module recording light;
(6), after light treatment module from service, the work service condition of recording light being treated module is transferred to control terminal by data transmission module.
Both effectively can have been realized effective setting for the treatment of time, treatment light intensity by above-mentioned setting, the situation avoiding treatment time inadequate or long occurs, and then adapts to the use of different crowd.
Embodiment 4
The present embodiment optimizes the carrying carrier structure of device on the basis of embodiment 3, device described in the present embodiment is arranged in the eye hood configuration be made up of three-decker, the three-decker of this hood configuration is respectively internal layer, middle level and skin, as shown in Figure 2, specifically arranges as follows:
This internal layer eyes place respectively arranges a luminescence window 1, and this internal layer upper left quarter is provided with wears monitoring sensor arrangement window 3, and internal layer upper right quarter is then provided with sleep monitor module and settles window 4;
This middle level is hard layer, connected by holding wire 6 by two pieces of circuit boards 5, described circuit board 5 is provided with light with luminescence window 1 correspondence position and treats module 7, with wear monitoring sensor and settle window 3 correspondence position that wearing state monitoring modular 8 is installed, settle window 4 correspondence position that sleep monitor module 9 is installed with sleep monitor module, this circuit board 5 is gone back integrated power supply module 10, MCU controller 11, data transmission module 12, data recordin module 13 and clock module 14;
Described skin is arranged heat dissipation region 2; The eye hood configuration left and right sides is connected by elastic band.
By the setting of said structure, effectively can ensure the level of comfort worn, reduce the interference to user's sleep substantially, and effectively can also meet monitoring sleep status by this setting and effectively regulate the object of the eye intensity of light source, and then effectively reach the effect for the treatment of.
Above-described embodiment is only the preferred embodiments of the present invention, not limiting the scope of the invention, as long as adopt design principle of the present invention, and the change carried out non-creativeness work on this basis and make, all should belong within protection scope of the present invention.
Claims (10)
1. alleviate a medical treatment device for Fundus oculi lesion, it is characterized in that, comprising:
MCU controller: center controls and processing module;
Light treatment module: wherein comprising light source driver module and array of source two parts, the control instruction that light source driver module generates for receiving MCU controller, carrying out power amplification and driving light source array light-emitting;
Wearing state monitoring modular: Real-Time Monitoring is carried out to the wearing state of device;
Sleep monitor module: measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm, and regulate light Therapeutic mode according to sleep state;
Power module: for device provides stable power supply.
2. a kind of medical treatment device alleviating Fundus oculi lesion according to claim 1, is characterized in that, also comprise:
Control terminal: the usage data passed back for receiving system, and wirelessly device is controlled;
Data transmission module: in order to follow the transmitting-receiving carrying out control instruction and usage data between control terminal;
Data recordin module: the usage data of recording user;
Clock module: for generation of system time and date and time information;
Described power module is rechargable power supplies module, and it is made up of rechargeable type lithium battery and peripheral charge-discharge circuit.
3. a kind of medical treatment device alleviating Fundus oculi lesion according to claim 2, is characterized in that, described device is arranged in the eye hood configuration be made up of three-decker, and the three-decker of this hood configuration is respectively internal layer, middle level and skin, wherein, internal layer eyes place respectively arranges a luminescence window (1), and this internal layer upper left quarter is provided with wears monitoring sensor arrangement window (3), and internal layer upper right quarter is then provided with sleep monitor module and settles window (4), this middle level is hardware layer, connected by holding wire (6) by two pieces of circuit boards (5), upper and luminescence window (1) correspondence position of described circuit board (5) is provided with light and treats module (7), with wear monitoring sensor and settle window (3) correspondence position that wearing state monitoring modular (8) is installed, settle window (4) correspondence position that sleep monitor module (9) is installed with sleep monitor module, this circuit board (5) is gone back integrated power supply module (10), MCU controller (11), data transmission module (12), data recordin module (13) and clock module (14), described skin is arranged heat dissipation region (2), the eye hood configuration left and right sides is connected by elastic band.
4. a kind of medical treatment device alleviating Fundus oculi lesion according to claim 1, is characterized in that, the instrument of described measurement patient pulse ripple signal is photoplethysmographic sensor.
5. a kind of medical treatment device alleviating Fundus oculi lesion according to any one of Claims 1 to 4, is characterized in that, the process of described sleep state monitoring algorithm is:
(1) digital band-pass filter of 0.05Hz ~ 20Hz is adopted to carry out Filtering Processing to pulse wave signal;
(2) detect each cardiac cycle pulse wave peak value, and extract IPP sequence;
(3) the IPP average Mean_IPP in special time window is asked for;
(4) cubic spline interpolation algorithm is to IPP sequence interpolations;
(5) 4Hz sample rate is to IPP sequential sampling after interpolation;
(6) period map method tries to achieve IPP sequence power spectrum;
(7) extract LF and HF two partial power compose and calculate energy;
(8) the energy ratio LF/HF of LF and HF is asked for;
(9) when LF/HF is greater than threshold value 1, rapid-eye-movement sleep (REM sleep) state is judged to be; When LF/HF is less than or equal to threshold value 1, then enter lower step;
(10) when LF/HF is greater than threshold value 2, nonrapid eye movements,sleep state is judged to be; When LF/HF is less than or equal to threshold value 2, be then judged to be wakefulness.
6. a kind of medical treatment device alleviating Fundus oculi lesion according to claim 5, is characterized in that, described threshold value 1 is 1.71, and threshold value 2 is 0.996.
7. alleviate a control method for the medical treatment device of Fundus oculi lesion, it is characterized in that, comprising:
(1) adopt the wear condition of wearing state monitoring modular checkout gear, if do not wear, then proceed monitoring, if worn, then enter next step;
(2) adopt sleep monitor module to measure patient pulse's ripple signal, and import MCU controller into after signal is carried out AD conversion, monitor patient sleeps's state by MCU controller by sleep state monitoring algorithm;
(3) if do not enter sleep state, then light treatment module is not opened; If enter sleep state, then judge that this sleep state is rapid-eye-movement sleep (REM sleep) state or nonrapid eye movements,sleep state, regulate light Therapeutic mode according to sleep state.
8. a kind of control method alleviating the medical treatment device of Fundus oculi lesion according to claim 7, is characterized in that, before device is worn, arranged the running parameter of light treatment module by control terminal, operating process is:
A () is by data transmission module connection control terminal and device;
(b) running parameter of setting device on control terminal, and by data transmission module, running parameter is sent in MCU controller, monitoring result according to running parameter and wearing state monitoring modular and sleep monitor module controls the work that light treats module, and is treated the working condition of module by data recordin module recording light;
C, after () light treatment module from service, the working condition of recording light being treated module is transferred to control terminal by data transmission module.
9. a kind of control method alleviating the medical treatment device of Fundus oculi lesion according to claim 7 or 8, is characterized in that, the process of described sleep state monitoring algorithm is:
(1) digital band-pass filter of 0.05Hz ~ 20Hz is adopted to carry out Filtering Processing to pulse wave signal;
(2) detect each cardiac cycle pulse wave peak value, and extract IPP sequence;
(3) the IPP average Mean_IPP in special time window is asked for;
(4) cubic spline interpolation algorithm is to IPP sequence interpolations;
(5) 4Hz sample rate is to IPP sequential sampling after interpolation;
(6) period map method tries to achieve IPP sequence power spectrum;
(7) extract LF and HF two partial power compose and calculate energy;
(8) the energy ratio LF/HF of LF and HF is asked for;
(9) when LF/HF is greater than threshold value 1, rapid-eye-movement sleep (REM sleep) state is judged to be; When LF/HF is less than or equal to threshold value 1, then enter lower step;
(10) when LF/HF is greater than threshold value 2, nonrapid eye movements,sleep state is judged to be; When LF/HF is less than or equal to threshold value 2, be then judged to be wakefulness.
10. a kind of control method alleviating the medical treatment device of Fundus oculi lesion according to claim 9, is characterized in that, described threshold value 1 is 1.71, and threshold value 2 is 0.996.
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| CN201510476196.6A CN105125338A (en) | 2015-08-06 | 2015-08-06 | Medical instrument for relieving eyeground vasculopathy and control method of medical instrument |
| PCT/CN2016/089400 WO2017020682A1 (en) | 2015-08-06 | 2016-07-08 | Medical device for relieving fundus blood vessel diseases, and control method therefor |
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| WO2017020682A1 (en) * | 2015-08-06 | 2017-02-09 | 成都康拓邦科技有限公司 | Medical device for relieving fundus blood vessel diseases, and control method therefor |
| CN108430309A (en) * | 2016-11-30 | 2018-08-21 | 华为技术有限公司 | A kind of sleep monitor method, apparatus and terminal |
| CN108464837A (en) * | 2018-05-04 | 2018-08-31 | 重庆大学 | A kind of blood viscosity optics diagnosis and treatment integrated instrument and method towards domestic medicine |
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| CN116095922B (en) * | 2023-03-13 | 2023-08-18 | 广州易而达科技股份有限公司 | Lighting lamp control method and device, lighting lamp and storage medium |
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