CA1025856A - Quinoline-3-carboxamidotetrazole derivatives - Google Patents
Quinoline-3-carboxamidotetrazole derivativesInfo
- Publication number
- CA1025856A CA1025856A CA193,476A CA193476A CA1025856A CA 1025856 A CA1025856 A CA 1025856A CA 193476 A CA193476 A CA 193476A CA 1025856 A CA1025856 A CA 1025856A
- Authority
- CA
- Canada
- Prior art keywords
- carboxamidotetrazole
- quinoline
- derivatives
- carboxamidotetrazole derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB924973A GB1433774A (en) | 1973-02-26 | 1973-02-26 | Heterocyclic compounds apparatus for conveying articles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1025856A true CA1025856A (en) | 1978-02-07 |
Family
ID=9868317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA193,476A Expired CA1025856A (en) | 1973-02-26 | 1974-02-26 | Quinoline-3-carboxamidotetrazole derivatives |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5029574A (en) |
| AT (1) | AT329562B (en) |
| AU (1) | AU474797B2 (en) |
| BE (1) | BE811246A (en) |
| CA (1) | CA1025856A (en) |
| CH (1) | CH602707A5 (en) |
| DE (1) | DE2407744A1 (en) |
| FR (1) | FR2218896B1 (en) |
| GB (1) | GB1433774A (en) |
| IE (1) | IE38886B1 (en) |
| LU (1) | LU69479A1 (en) |
| NL (1) | NL7402613A (en) |
| SE (1) | SE7401984L (en) |
| ZA (1) | ZA74883B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8765957B2 (en) | 2009-03-20 | 2014-07-01 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
| US9931334B2 (en) | 2005-12-28 | 2018-04-03 | Vertex Pharmaceuticals Incorporated | Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US10272046B2 (en) | 2012-02-27 | 2019-04-30 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US10646481B2 (en) | 2008-08-13 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2324304A2 (en) * | 1975-09-22 | 1977-04-15 | Roussel Uclaf | Analgesic (4)-hydroxy-quinoline-(3)-amides - prepd. from a quinoline-(3)-carboxyl chloride and an amine |
| US4186201A (en) | 1977-02-07 | 1980-01-29 | Riker Laboratories, Inc. | Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds |
| US4390541A (en) | 1980-12-19 | 1983-06-28 | Lilly Industries Limited | Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease |
| FR2509728A1 (en) * | 1981-07-17 | 1983-01-21 | Roussel Uclaf | NOVEL QUINOLINE DERIVATIVES, THEIR SALTS, PREPARATION METHOD, MEDICAMENT APPLICATION AND COMPOSITIONS COMPRISING THE SAME |
| US4377579A (en) | 1981-12-03 | 1983-03-22 | Minnesota Mining And Manufacturing Company | N-(Tetrazol-5-yl)phenazine-1-carboxamides |
| FR2537140B1 (en) * | 1982-12-07 | 1986-07-18 | Roussel Uclaf | NOVEL 4-HYDROXY-3-QUINOLEINE CARBOXAMIDE DERIVATIVES, SALTS THEREOF, PROCESS FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS, AND COMPOSITIONS CONTAINING THEM |
| EP0298134B1 (en) * | 1987-01-20 | 1992-11-11 | Dainippon Pharmaceutical Co., Ltd. | Aromatic heterocyclic carboxylic acid amide derivatives, process for their preparation, and pharmaceutical composition containing same |
| US4959363A (en) * | 1989-06-23 | 1990-09-25 | Sterling Drug Inc. | Quinolonecarboxamide compounds, their preparation and use as antivirals. |
| US6034100A (en) * | 1993-03-10 | 2000-03-07 | Otsuka Pharmaceutical Co., Ltd. | Method for inhibiting cytokine secretion |
| US6143760A (en) | 1997-08-25 | 2000-11-07 | Neurogen Corporation | Substituted 4-oxo-napthyridine-3-carboxamides: GABA brain receptor ligands |
| WO1999010347A1 (en) * | 1997-08-25 | 1999-03-04 | Neurogen Corporation | Substituted 4-oxo-napthyridine-3-carboxamides as gaba brain receptor ligands |
| WO1999043661A2 (en) * | 1998-02-26 | 1999-09-02 | Neurogen Corporation | Substituted cycloalkyl-4-oxonicotinic carboxamides; gaba brain receptor ligands |
| JP4532263B2 (en) * | 2002-05-14 | 2010-08-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Substituted quinolone carboxylic acids, derivatives thereof, sites of action, and uses thereof |
| CN100471842C (en) | 2003-07-24 | 2009-03-25 | 安斯泰来制药有限公司 | Quinolone derivative or its salt |
| LT2489659T (en) | 2004-06-24 | 2018-03-26 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| SI2502911T1 (en) * | 2004-06-24 | 2017-07-31 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
| RU2525115C2 (en) * | 2004-06-24 | 2014-08-10 | Вертекс Фармасьютикалз Инкорпорейтед | Method of modulating transporters of atp-binding cassette |
| US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
| US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
| EP2821401B1 (en) | 2012-03-02 | 2020-09-09 | Takeda Pharmaceutical Company Limited | Dihydroquinolinone compounds as modulators of the muscarininc m1 receptor |
| EP2921480B1 (en) | 2012-11-19 | 2017-10-11 | Takeda Pharmaceutical Company Limited | Nitrogen-containing heterocyclic compound |
| CN105330602B (en) * | 2015-12-07 | 2018-02-09 | 江南大学 | A kind of deccox analog and its application |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1383088A (en) * | 1972-07-03 | 1975-02-05 | Allen & Hanburys Ltd | Pharmacologically active quinaldamide derivatives |
-
1973
- 1973-02-26 GB GB924973A patent/GB1433774A/en not_active Expired
-
1974
- 1974-02-08 IE IE00249/74A patent/IE38886B1/en unknown
- 1974-02-11 ZA ZA740883A patent/ZA74883B/en unknown
- 1974-02-14 AU AU65592/74A patent/AU474797B2/en not_active Expired
- 1974-02-14 SE SE7401984A patent/SE7401984L/xx unknown
- 1974-02-18 DE DE19742407744 patent/DE2407744A1/en active Pending
- 1974-02-18 CH CH224374A patent/CH602707A5/xx not_active IP Right Cessation
- 1974-02-19 BE BE141102A patent/BE811246A/en unknown
- 1974-02-22 LU LU69479A patent/LU69479A1/xx unknown
- 1974-02-25 AT AT149974A patent/AT329562B/en not_active IP Right Cessation
- 1974-02-25 FR FR7406327A patent/FR2218896B1/fr not_active Expired
- 1974-02-25 JP JP49022232A patent/JPS5029574A/ja active Pending
- 1974-02-26 NL NL7402613A patent/NL7402613A/xx not_active Application Discontinuation
- 1974-02-26 CA CA193,476A patent/CA1025856A/en not_active Expired
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9931334B2 (en) | 2005-12-28 | 2018-04-03 | Vertex Pharmaceuticals Incorporated | Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US10537565B2 (en) | 2005-12-28 | 2020-01-21 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US11291662B2 (en) | 2005-12-28 | 2022-04-05 | Vertex Pharmaceuticals Incorporated | Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
| US10646481B2 (en) | 2008-08-13 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US8765957B2 (en) | 2009-03-20 | 2014-07-01 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US8835639B2 (en) | 2009-03-20 | 2014-09-16 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US9371287B2 (en) | 2009-03-20 | 2016-06-21 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US9751839B2 (en) | 2009-03-20 | 2017-09-05 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| US10272046B2 (en) | 2012-02-27 | 2019-04-30 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US11147770B2 (en) | 2012-02-27 | 2021-10-19 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US11752106B2 (en) | 2012-02-27 | 2023-09-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2218896A1 (en) | 1974-09-20 |
| LU69479A1 (en) | 1975-05-21 |
| FR2218896B1 (en) | 1977-09-09 |
| AT329562B (en) | 1976-05-25 |
| SE7401984L (en) | 1974-08-27 |
| AU6559274A (en) | 1975-08-14 |
| BE811246A (en) | 1974-08-19 |
| DE2407744A1 (en) | 1974-08-29 |
| NL7402613A (en) | 1974-08-28 |
| ZA74883B (en) | 1974-12-24 |
| IE38886L (en) | 1974-08-26 |
| IE38886B1 (en) | 1978-06-21 |
| ATA149974A (en) | 1975-08-15 |
| CH602707A5 (en) | 1978-07-31 |
| AU474797B2 (en) | 1976-08-05 |
| JPS5029574A (en) | 1975-03-25 |
| GB1433774A (en) | 1976-04-28 |
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