AU6105300A - Vinyl ether lipids with cleavable hydrophilic headgroups - Google Patents

Vinyl ether lipids with cleavable hydrophilic headgroups

Info

Publication number
AU6105300A
AU6105300A AU61053/00A AU6105300A AU6105300A AU 6105300 A AU6105300 A AU 6105300A AU 61053/00 A AU61053/00 A AU 61053/00A AU 6105300 A AU6105300 A AU 6105300A AU 6105300 A AU6105300 A AU 6105300A
Authority
AU
Australia
Prior art keywords
vinyl ether
ether lipids
hydrophilic headgroups
cleavable hydrophilic
cleavable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61053/00A
Inventor
Jeremy A. Boomer
Robert Haynes
David H Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of AU6105300A publication Critical patent/AU6105300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
AU61053/00A 1999-07-16 2000-07-17 Vinyl ether lipids with cleavable hydrophilic headgroups Abandoned AU6105300A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14430199P 1999-07-16 1999-07-16
US60144301 1999-07-16
US14655299P 1999-07-30 1999-07-30
US60146552 1999-07-30
PCT/US2000/019430 WO2001005375A1 (en) 1999-07-16 2000-07-17 Vinyl ether lipids with cleavable hydrophilic headgroups

Publications (1)

Publication Number Publication Date
AU6105300A true AU6105300A (en) 2001-02-05

Family

ID=26841867

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61053/00A Abandoned AU6105300A (en) 1999-07-16 2000-07-17 Vinyl ether lipids with cleavable hydrophilic headgroups

Country Status (3)

Country Link
EP (1) EP1202714A1 (en)
AU (1) AU6105300A (en)
WO (1) WO2001005375A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162319A0 (en) 2001-12-04 2005-11-20 Univ Ben Gurion Amphiphilic compounds and vesicles/liposomes for organ-specific drug targeting
EP1498420B1 (en) 2002-03-29 2017-02-01 Nof Corporation Phospholipid derivative
WO2004029104A1 (en) * 2002-09-30 2004-04-08 Nof Corporation Phospholipid derivative
WO2004060899A1 (en) 2003-01-06 2004-07-22 Nof Corporation Phospholipid derivatives and process for the production there
US7399877B2 (en) 2003-03-20 2008-07-15 Nof Corporation Phospholipid derivative
NZ733634A (en) 2009-12-01 2022-10-28 Translate Bio Inc Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
LT2717893T (en) 2011-06-08 2019-08-12 Translate Bio, Inc. Lipid nanoparticle compositions and methods for mrna delivery
AU2012267578B2 (en) 2011-06-08 2017-04-20 Translate Bio, Inc. Cleavable lipids
US9546128B2 (en) 2012-03-29 2017-01-17 Shire Human Genetic Therapies, Inc. Ionizable cationic lipids
EP2830596B1 (en) * 2012-03-29 2020-12-30 Translate Bio, Inc. Lipid-derived neutral nanoparticles
EP3536787A1 (en) 2012-06-08 2019-09-11 Translate Bio, Inc. Nuclease resistant polynucleotides and uses thereof
PL3467108T3 (en) 2013-03-14 2024-09-30 Translate Bio, Inc. Methods for purification of messenger rna
CN115154620A (en) 2013-03-14 2022-10-11 夏尔人类遗传性治疗公司 CFTR MRNA compositions and related methods and uses
AU2014340092B2 (en) 2013-10-22 2019-09-19 Translate Bio, Inc. mRNA therapy for Argininosuccinate Synthetase Deficiency
EA034103B1 (en) 2013-10-22 2019-12-27 Транслейт Био, Инк. METHOD OF TREATING PHENYLKETONURIA USING mRNA
AU2014340155B2 (en) 2013-10-22 2018-11-01 Massachusetts Institute Of Technology Lipid formulations for delivery of messenger RNA
AU2015249312B2 (en) 2014-04-25 2021-07-29 Translate Bio, Inc. Methods for purification of messenger RNA
ES2750686T3 (en) 2014-05-30 2020-03-26 Translate Bio Inc Biodegradable lipids for nucleic acid administration
KR102559979B1 (en) 2014-06-24 2023-07-25 샤이어 휴먼 지네틱 테라피즈 인크. Stereochemically enriched compositions for delivery of nucleic acids
CA3041345A1 (en) * 2016-11-10 2018-05-17 Shrirang KARVE Improved process of preparing mrna-loaded lipid nanoparticles
EP3585417B1 (en) 2017-02-27 2023-02-22 Translate Bio, Inc. Method of making a codon-optimized cftr mrna
EP3624824B1 (en) 2017-05-16 2024-07-10 Translate Bio, Inc. Codon-optimized mrna encoding cftr for use in treating cystic fibrosis
KR20210060480A (en) 2018-08-24 2021-05-26 트랜슬레이트 바이오 인코포레이티드 Method for purifying messenger RNA
WO2021127641A1 (en) 2019-12-20 2021-06-24 Translate Bio, Inc. Improved process of preparing mrna-loaded lipid nanoparticles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5277913A (en) * 1991-09-09 1994-01-11 Thompson David H Liposomal delivery system with photoactivatable triggered release

Also Published As

Publication number Publication date
EP1202714A1 (en) 2002-05-08
WO2001005375A1 (en) 2001-01-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase