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Odds of Using Cord Blood

Odds of a child having a condition that can be treated by Cord Blood Stem Cells

Table researched by Frances Verter, PhD ©2014-2024; References Below

References

  • Lifetime Probability of Stem Cell Transplant in USA: Nietfeld JJ, Pasquini MC, Logan, BR, Verter, F, Horowitz MM. Lifetime Probabilities of Hematopoietic Stem Cell Transplantation in the U.S. BBMT 2008; 14(3)316–322. doi:10.1016/j.bbmt.2007.12.493
  • Thalassemia Statistics Worldwide: News Medical Life Sciences. Thalassemia Prevalence. Last updated 2021-05-22
  • Thalassemia Statistics India: Colah R, Italia K, Gorakshakar A. Burden of thalassemia in India: The road map for control.  Pediatric Hematology Oncology J 2017; 2(4):79-84. doi.org/10.1016/j.phoj.2017.10.002
  • Autism: Statistic 1 in 36 children age 8 have autism spectrum disorders is 2021 USA prevalence from Centers for Disease Control (CDC).
  • Autism review of latest cord blood trial: Kurtzberg J. Results from the Duke ACT Study of Cord Blood for Autism: Highlights for Parents. Parent's Guide to Cord Blood Foundation Newsletter Published 2020-07 
  • Cerebral Palsy: Statistic 1 in 345 children age 8 is USA prevalence from Centers for Disease Control (CDC).
  • Cerebral Palsy: Incidence of 1.5 in 1000 births in Australia according to Cerebral Palsy Alliance.
  • Cerebral Palsy: Incidence increases with prematurity. The rate is about 1.4 per 1000 babies at 36 weeks gestation and increases to 15% among babies born between 24-27 weeks gestation. See Stavsky M, Mor O, Mastrolia SA, Greenbaum S, Than G, Erez O. Cerebral Palsy—Trends in Epidemiology and Recent Development in Prenatal Mechanisms of Disease, Treatment, and Prevention. Frontiers Pediatrics 2017; 5:21. doi:10.3389/fped.2017.00021
  • Cerebral Palsy review of all cell therapy trials: Paton MCB, Finch‐Edmondson M, Fahey MC, London J, Badawi N, Novak I. Fifteen years of human research using stem cells for cerebral palsy: A review of the research landscape. J Paediatrics Child Health 2021; 57:295-296. doi.org/10.1111/jpc.15329
  • Cerebral Palsy review of allogeneic cord blood trials: Paton MCB, Wall DA, Elwood N, Chiang KY, Cowie G, Novak I, Finch-Edmondson M. Safety of allogeneic umbilical cord blood infusions for the treatment of neurological conditions: a systematic review of clinical studies. Cytotherapy 2021; 8 pages. doi.org/10.1016/j.jcyt.2021.07.001
  • Hypoxic Ischemic Encephalopathy (HIE): Statistics 2 per 1000 are from Smith, J. etal. BJOG 2000;107(4):461-6 doi: 10.1111/j.1471-0528.2000.tb13262.x
  • Expanded Access Program clinical trial NCT03327467 offers cord blood therapy (both autologous and sibling) to children with brain injuries including: Cerebral Palsy (CP), Hypoxic Ischemic Encephalopathy (HIE), Apraxia, and others. Apply here.
  • Congenital Heart Defects: Statistic 9.4 per 1000 births from Liu Y, Chen S, Zuhlke L, Black GC, Choy MK, Li N, Keavney BD. Global birth prevalence of congenital heart defects 1970–2017: updated systematic review and meta-analysis of 260 studies. International Journal of Epidemiology. 2019; 48(2):455–463. doi:10.1093/ije/dyz009
  • Congenital Heart Defects requiring surgery: Statistics 1 in 200 births from Yale Medicine Dept. Pediatric Congenital Heart Surgery
  • Congenital Heart Defects: Statistic 1 million children and 1.4 million adults living with CHD is USA prevalence in 2010. Number living with CHD is rising because more babies survive. Gilboa SM, Devine OJ, Kucik JE, Oster ME, Riehle-Colarusso T, Nembhard WN, ...  Marelli AJ. Congenital Heart Defects in the United States: Estimating the Magnitude of the Affected Population in 2010. Circulation 2016; 134(2):101-109. doi:10.1161/CIRCULATIONAHA.115.019307 
  • Congenital Heart Defect surgery with autologous cord blood: Chasovskyi, K., Fedevych, O., Vorobiova, G., Zhovnir, V., Maksimenko, A., Boychenko, O., Lysak, Y., Cohen, G. and Yemets, I., 2012. Arterial switch operation in the first hours of life using autologous umbilical cord blood. Annals Thoracic Surgery 2012; 93(5):1571-1576. doi:10.1016/j.athoracsur.2012.01.104
  • Premature Lungs: Statistic BronchoPulmonary Dysplasia (BPD) 25% babies born weighing under 1500gm from Van Marter LJ. Epidemiology of bronchopulmonary dysplasia. Semin Fetal Neonatal Med. 2009;14(6):358-366 doi: 10.1016/j.siny.2009.08.007.
  • Premature Lungs review of novel treatments: Bonadies L, Zaramella P, Porzionato A, Perilongo G, Muraca M, Baraldi E. Present and Future of Bronchopulmonary Dysplasia. J Clin Med 2020; 9(5):1539. doi.org/10.3390/jcm9051539
  • Premature Lungs PNEUMOSTEM® product for preventive treatment of bronchopulmonary dysplasia (BPD) manufactured in South Korea
  • Cartilage Tear: Statistics on occurrence from Louw QA, Manilall J, Grimmer KA. Epidemiology of knee injuries among adolescents: a systematic review. Brit. J Sports Med 2008;42(1)2-10. doi:10.1136/bjsm.2007.035360
  • Cartilage Tear CARTISTEM® product approved in South Korea for treatment of repetitive and/or traumatic cartilage degeneration including degenerative osteoarthritis(OA) without age limit