Sameh Fayek
Working place
Andrology department, Kasr Al-Ainy Hospital, Cairo University
⦁ Resident of Andrology& STDs at Andrology department Cairo University (9/2003 up to 9/2006)
⦁ Clinical officer of Andrology& STDs (3/2008 till 7/2008)
⦁ Assistant lecturer of Andrology& STDs (7/2008 till 7/2012)
⦁ Lecturer of Andrology& STDs (7/2012 till now)
Postgraduate Degrees
⦁ MD of Andrology& STDs Cairo University (4/2012)
⦁ Master of Dermatology & STDs Cairo University (2/2008)
⦁ Diploma of Urology Al-Azhar University (11/2008)
⦁ Diploma of laser National Institute of Laser and Applicable Sciences (1/2010)
⦁ Diploma in total Quality management for health care reform AUC (6-2008)
⦁ Bachelor degree of medicine and surgery Cairo University(6/2002)
Andrology department, Kasr Al-Ainy Hospital, Cairo University
⦁ Resident of Andrology& STDs at Andrology department Cairo University (9/2003 up to 9/2006)
⦁ Clinical officer of Andrology& STDs (3/2008 till 7/2008)
⦁ Assistant lecturer of Andrology& STDs (7/2008 till 7/2012)
⦁ Lecturer of Andrology& STDs (7/2012 till now)
Postgraduate Degrees
⦁ MD of Andrology& STDs Cairo University (4/2012)
⦁ Master of Dermatology & STDs Cairo University (2/2008)
⦁ Diploma of Urology Al-Azhar University (11/2008)
⦁ Diploma of laser National Institute of Laser and Applicable Sciences (1/2010)
⦁ Diploma in total Quality management for health care reform AUC (6-2008)
⦁ Bachelor degree of medicine and surgery Cairo University(6/2002)
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Patients and methods: we prospectively recruited 60 patients with erectile dysfunction and controls between July 2015 and July 2016. The 30 patients were suffering from refractory veno-occlusive erectile dysfunction that was proven by investigations. They were scheduled for penile implant. The 30 controls were scheduled for repair of their fracture. We measured miRNAs (200a & 206) and nitric oxide (NO) in cavernous tissue and serum of both patients with erectile dysfunction and controls.
Results: a significant association was found between the two mentioned miRNAs and erectile dysfunction (p < 0.001). Mean level of nitric oxide (NO) in cavernous tissue of the controls was significantly higher than that in the patients (p < 0.001). miRNA 200a showed a cutoff value of 1.135 with 95% sensitivity and 100% specificity while miRNA 206 showed a cutoff value of 1.125 with 100% sensitivity and 100% specificity.
Conclusions: to the best of our knowledge, our study is the first report to measure the level of miRNAs in the cavernous tissue using a human tissue. Furthermore, this study can be considered a good step of deploying miRNAs through a blood test to detect early negative changes that lead to erectile dysfunction. Finally, we recommend more studies to be conducted to better understand if these miRNAs are involved in the pathophysiology of veno-occlusive erectile dysfunction.
outpatient clinic complaining of manifestations of partial androgen deficiency in aging males
(PADAM). In this study (750 mg/day) of Tribulus terrestris in 3 divided doses, each of 250 mg, as
an endogenous testosterone enhancer had been tried for a duration of 3 months and the evaluation of
its effect had been monitored for each patient concerning its effect on serum testosterone (total and
free) and luteinizing hormone (LH), as well as its impact on erectile function, which was evaluated
by the International Index of Erectile Function-5 (IIEF-5) questionnaire for those patients. Results
showed a statistically significant difference in the level of testosterone (total and free) and IIEF-5,
but no statistically significant difference in the level of LH before and after treatment. Also, the study
showed statistically significant correlation between testosterone (total and free) and IIEF-5, but no
statistically significant correlation between the level of LH and the IIEF-5 before and after treatment.
Books
Patients and methods: we prospectively recruited 60 patients with erectile dysfunction and controls between July 2015 and July 2016. The 30 patients were suffering from refractory veno-occlusive erectile dysfunction that was proven by investigations. They were scheduled for penile implant. The 30 controls were scheduled for repair of their fracture. We measured miRNAs (200a & 206) and nitric oxide (NO) in cavernous tissue and serum of both patients with erectile dysfunction and controls.
Results: a significant association was found between the two mentioned miRNAs and erectile dysfunction (p < 0.001). Mean level of nitric oxide (NO) in cavernous tissue of the controls was significantly higher than that in the patients (p < 0.001). miRNA 200a showed a cutoff value of 1.135 with 95% sensitivity and 100% specificity while miRNA 206 showed a cutoff value of 1.125 with 100% sensitivity and 100% specificity.
Conclusions: to the best of our knowledge, our study is the first report to measure the level of miRNAs in the cavernous tissue using a human tissue. Furthermore, this study can be considered a good step of deploying miRNAs through a blood test to detect early negative changes that lead to erectile dysfunction. Finally, we recommend more studies to be conducted to better understand if these miRNAs are involved in the pathophysiology of veno-occlusive erectile dysfunction.
outpatient clinic complaining of manifestations of partial androgen deficiency in aging males
(PADAM). In this study (750 mg/day) of Tribulus terrestris in 3 divided doses, each of 250 mg, as
an endogenous testosterone enhancer had been tried for a duration of 3 months and the evaluation of
its effect had been monitored for each patient concerning its effect on serum testosterone (total and
free) and luteinizing hormone (LH), as well as its impact on erectile function, which was evaluated
by the International Index of Erectile Function-5 (IIEF-5) questionnaire for those patients. Results
showed a statistically significant difference in the level of testosterone (total and free) and IIEF-5,
but no statistically significant difference in the level of LH before and after treatment. Also, the study
showed statistically significant correlation between testosterone (total and free) and IIEF-5, but no
statistically significant correlation between the level of LH and the IIEF-5 before and after treatment.