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SMG7

From Wikipedia, the free encyclopedia
SMG7
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesSMG7, C1orf16, EST1C, SGA56M, nonsense mediated mRNA decay factor, SMG7 nonsense mediated mRNA decay factor
External IDsOMIM: 610964; MGI: 2682334; HomoloGene: 32235; GeneCards: SMG7; OMA:SMG7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001005507
NM_001160256
NM_001160257
NM_001359257

RefSeq (protein)

NP_001005507
NP_001153728
NP_001153729
NP_001346186

Location (UCSC)Chr 1: 183.47 – 183.6 MbChr 1: 152.71 – 152.78 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein SMG7 is a protein that in humans is encoded by the SMG7 gene.[5][6][7][8]


References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000116698Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042772Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Ohnishi T, Yamashita A, Kashima I, Schell T, Anders KR, Grimson A, et al. (November 2003). "Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7". Molecular Cell. 12 (5): 1187–200. doi:10.1016/S1097-2765(03)00443-X. PMID 14636577.
  6. ^ Fukuhara N, Ebert J, Unterholzner L, Lindner D, Izaurralde E, Conti E (February 2005). "SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway". Molecular Cell. 17 (4): 537–47. doi:10.1016/j.molcel.2005.01.010. PMID 15721257.
  7. ^ "Entrez Gene: SMG7 Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)".
  8. ^ Yang L, Kraft VA, Pfeiffer S, Merl-Pham J, Bao X, An Y, et al. (June 2020). "Nonsense-mediated decay factor SMG7 sensitizes cells to TNFα-induced apoptosis via CYLD tumor suppressor and the noncoding oncogene Pvt1". Molecular Oncology. 14 (10): 2420–2435. doi:10.1002/1878-0261.12754. PMC 7530794. PMID 32602581.

Further reading

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