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Etamiphylline

From Wikipedia, the free encyclopedia
Etamiphylline
Ball-and-stick model of the etamiphylline molecule
Names
Preferred IUPAC name
7-[2-(Diethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.005.678 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C13H21N5O2/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3/h9H,5-8H2,1-4H3 ☒N
    Key: AWKLBIOQCIORSB-UHFFFAOYSA-N ☒N
  • CCN(CC)CCn1cnc2c1c(=O)n(c(=O)n2C)C
Properties
C13H21N5O2
Molar mass 279.33814
Pharmacology
R03DA06 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Etamiphylline or etamiphyllin (INN)[1] is a xanthine intended for use as an anti-asthma agent. It has shown poor to absent effects in human clinical trials.[2][3]

References

[edit]
  1. ^ "International Non-Proprietary Names for Pharmaceutical Preparations. Recommended International Non-Proprietary Names (Rec. I.N.N.): List 3" (PDF). World Health Organization. p. 467. Retrieved 29 December 2016.
  2. ^ Vazquez, C; Labayru, T; Rodriguez-Soriano, J (1984). "Poor bronchodilator effect of oral etamiphylline in asthmatic children". Lancet. 1 (8382): 914. doi:10.1016/s0140-6736(84)91380-1. PMID 6143224.
  3. ^ Addis, GJ (1984). "Absence of bronchodilatory effect from etamiphylline". Lancet. 1 (8385): 1083. doi:10.1016/s0140-6736(84)91497-1. PMID 6144017.