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DYNLT1

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DYNLT1
Identifiers
AliasesDYNLT1, CW-1, TCTEL1, tctex-1, dynein light chain Tctex-type 1, TCTEX1
External IDsOMIM: 601554; MGI: 98643; HomoloGene: 4754; GeneCards: DYNLT1; OMA:DYNLT1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006519
NM_001291602
NM_001291603

NM_009342

RefSeq (protein)

NP_001278531
NP_001278532
NP_006510

NP_001160099
NP_001186877
NP_001160102
NP_001160101
NP_033368

Location (UCSC)Chr 6: 158.64 – 158.64 MbChr 17: 6.7 – 6.7 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Dynein light chain Tctex-type 1 is a protein that in humans is encoded by the DYNLT1 gene.[5][6][7]

Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. TCTEX1 is a dynein light chain involved in cargo binding (Chuang et al., 2005).[supplied by OMIM][7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000146425Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000096255Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Watanabe TK, Fujiwara T, Shimizu F, Okuno S, Suzuki M, Takahashi E, Nakamura Y, Hirai Y (Jul 1996). "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q". Cytogenet Cell Genet. 73 (1–2): 153–6. doi:10.1159/000134329. PMID 8646886.
  6. ^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (Nov 2005). "Cytoplasmic dynein nomenclature". J Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMC 2171247. PMID 16260502.
  7. ^ a b "Entrez Gene: DYNLT1 dynein, light chain, Tctex-type 1".

Further reading

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