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Citryl-CoA lyase

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citryl-CoA lyase
Identifiers
EC no.4.1.3.34
CAS no.131095-35-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
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The enzyme citryl-CoA lyase (EC 4.1.3.34) catalyzes the chemical reaction

(3S)-citryl-CoA acetyl-CoA + oxaloacetate

This enzyme belongs to the family of lyases, specifically the oxo-acid-lyases, which cleave carbon–carbon bonds. The systematic name of this enzyme class is (3S)-citryl-CoA oxaloacetate-lyase (acetyl-CoA-forming). This enzyme is also called (3S)-citryl-CoA oxaloacetate-lyase. This enzyme participates in citrate cycle (tca cycle).

References

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  • Dimroth P, Loyal R, Eggerer H (1977). "Characterization of the isolated transferase subunit of citrate lyase as a CoA-Transferase. Evidence against a covalent enzyme-substrate intermediate". Eur. J. Biochem. 80 (2): 479–88. doi:10.1111/j.1432-1033.1977.tb11903.x. PMID 336371.
  • Lill U, Schreil A, Eggerer H (1982). "Isolation of enzymically active fragments formed by limited proteolysis of ATP citrate lyase". Eur. J. Biochem. 125 (3): 645–50. doi:10.1111/j.1432-1033.1982.tb06731.x. PMID 6749502.