Jump to content

Arofylline

From Wikipedia, the free encyclopedia
Arofylline
Names
IUPAC name
3-(4-Chlorophenyl)-1-propyl-7H-purine-2,6-dione
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • CCCN1C(=O)C2=C(N=CN2)N(C1=O)C3=CC=C(C=C3)Cl
Properties
C14H13ClN4O2
Molar mass 304.73 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Arofylline (codenamed LAS 31025) is a phosphodiesterase inhibitor.[1]

References

[edit]
  1. ^ Ferrer, L; Alberola, J; Queralt, M; Brazís, P; Rabanal, R; Llenas, J; Puigdemont, A (1999). "Clinical anti-inflammatory efficacy of arofylline, a new selective phosphodiesterase-4 inhibitor, in dogs with atopic dermatitis". The Veterinary Record. 145 (7): 191–4. PMID 10501583.